Chinese Chemical Letters, ISSN 1001-8417, 05/2019, Volume 30, Issue 5, pp. 1071 - 1074
Two fluorescent “off-on” probes YYH1 and YYH2 were used for bioimaging mitochondrial polarity and viscosity. Two fluorescent “off-on” probes YYH1 and YYH2 were...
Microviscosity | Mitochondria | Micropolarity | Fluorescent probe
Microviscosity | Mitochondria | Micropolarity | Fluorescent probe
Journal Article
ACS Nano, ISSN 1936-0851, 05/2018, Volume 12, Issue 5, pp. 4398 - 4407
Microscopic viscosity (microviscosity) is a key determinant of diffusion in the cell and defines the rate of biological processes occurring at the nanoscale,...
diffusion | fluorescence | molecular rotors | cell biophysics | organelle | microviscosity | FLIM | MATERIALS SCIENCE, MULTIDISCIPLINARY | MEMBRANE MICROVISCOSITY | MITOCHONDRIA | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | VISCOSITY | MICROSCOPY | LIVE CELLS | CHEMISTRY, MULTIDISCIPLINARY | BIOLOGY | ENDOPLASMIC-RETICULUM | LIVING CELLS
diffusion | fluorescence | molecular rotors | cell biophysics | organelle | microviscosity | FLIM | MATERIALS SCIENCE, MULTIDISCIPLINARY | MEMBRANE MICROVISCOSITY | MITOCHONDRIA | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | VISCOSITY | MICROSCOPY | LIVE CELLS | CHEMISTRY, MULTIDISCIPLINARY | BIOLOGY | ENDOPLASMIC-RETICULUM | LIVING CELLS
Journal Article
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Full Text
Front Cover: Fluorescent Molecular Rotors for Viscosity Sensors (Chem. Eur. J. 52/2018)
Chemistry – A European Journal, ISSN 0947-6539, 09/2018, Volume 24, Issue 52, pp. 13688 - 13688
Fluorescent molecular rotors (FMRs) can act as viscosity sensors in various media. A review of recently developed FMRs with their design strategies for...
fluorescence dynamics | molecular rotors | fluorescent molecular rotors | microviscosity | viscosity sensors
fluorescence dynamics | molecular rotors | fluorescent molecular rotors | microviscosity | viscosity sensors
Journal Article
Angewandte Chemie (International ed. in English), ISSN 1433-7851, 7/2018, Volume 57, Issue 29, pp. 8891 - 8895
The measurement of physicochemical parameters in living cells can provide information specific to individual cell organelles, helping us to understand...
Mitochondria | Cellular Polarity | Cellular Microviscosity | Fluorescent Probes
Mitochondria | Cellular Polarity | Cellular Microviscosity | Fluorescent Probes
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 09/2018, Volume 24, Issue 52, p. n/a
Recently developed fluorescent molecular rotors (FMRs) acting as viscosity sensors in various media, such as biological and microfluidic environments, are...
fluorescence dynamics | molecular rotors | fluorescent molecular rotors | microviscosity | viscosity sensors | Sensors | Viscosity | Fluorescence | Chromophores | Derivatives | Rotors
fluorescence dynamics | molecular rotors | fluorescent molecular rotors | microviscosity | viscosity sensors | Sensors | Viscosity | Fluorescence | Chromophores | Derivatives | Rotors
Journal Article
The Journal of Physical Chemistry B, ISSN 1520-6106, 01/2018, Volume 122, Issue 1, pp. 181 - 193
The thermoreversible sol–gel transition of pluronic F127 is markedly altered even with addition of submicellar concentration of sodium dodecyl sulfate (SDS)...
TRIBLOCK COPOLYMER | IONIC SURFACTANTS | ABA BLOCK-COPOLYMERS | MICROPOLARITY | DRUG-DELIVERY | FORMULATIONS | CHEMISTRY, PHYSICAL | MEDIA | F-127 GELS | MICROVISCOSITY | AQUEOUS-SOLUTION
TRIBLOCK COPOLYMER | IONIC SURFACTANTS | ABA BLOCK-COPOLYMERS | MICROPOLARITY | DRUG-DELIVERY | FORMULATIONS | CHEMISTRY, PHYSICAL | MEDIA | F-127 GELS | MICROVISCOSITY | AQUEOUS-SOLUTION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 23, pp. 9225 - 9230
Encapsulated microbubbles are well established as highly effective contrast agents for ultrasound imaging. There remain, however, some significant challenges...
Viscosity | Histograms | Bubbles | Dyes | Imaging | Ultrasonography | Fluorescence | Lipids | Chemical composition | Coatings | Microviscosity | FLIM | MODEL | MULTIDISCIPLINARY SCIENCES | microviscosity | Microbubbles - standards | Models, Chemical | Molecular Dynamics Simulation | Optical Imaging - methods | Viscoelasticity | Microbubbles | Usage | Properties | Fluorescence microscopy | Physical Sciences
Viscosity | Histograms | Bubbles | Dyes | Imaging | Ultrasonography | Fluorescence | Lipids | Chemical composition | Coatings | Microviscosity | FLIM | MODEL | MULTIDISCIPLINARY SCIENCES | microviscosity | Microbubbles - standards | Models, Chemical | Molecular Dynamics Simulation | Optical Imaging - methods | Viscoelasticity | Microbubbles | Usage | Properties | Fluorescence microscopy | Physical Sciences
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2007, Volume 5, Issue 11, pp. 1669 - 1678
Viscosity is a measure of the resistance of a fluid against gradients in flow ( shear rate). Both flow and viscosity play an important role in all biological...
PLASMA VISCOSITY | ENDOTHELIAL-CELLS | MEMBRANE-FLUIDITY | CHEMISTRY, ORGANIC | RHEOLOGY | SMOKING | MICROVISCOSITY | BLOOD-VISCOSITY | PHOTOBLEACHING RECOVERY | PHOSPHOLIPID-BILAYERS | PROBES | Viscosity | Spectrometry, Fluorescence | Molecular Probes - analysis | Biosensing Techniques - methods | Molecular Probes - chemistry | Rheology - methods
PLASMA VISCOSITY | ENDOTHELIAL-CELLS | MEMBRANE-FLUIDITY | CHEMISTRY, ORGANIC | RHEOLOGY | SMOKING | MICROVISCOSITY | BLOOD-VISCOSITY | PHOTOBLEACHING RECOVERY | PHOSPHOLIPID-BILAYERS | PROBES | Viscosity | Spectrometry, Fluorescence | Molecular Probes - analysis | Biosensing Techniques - methods | Molecular Probes - chemistry | Rheology - methods
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2018, Volume 57, Issue 29, pp. 8891 - 8895
The measurement of physicochemical parameters in living cells can provide information on individual cellular organelles, helping us to understand subcellular...
cellular polarity | cellular microviscosity | mitochondria | fluorescent probes | ORGANELLES | COPPER | MICROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | DEPOLARIZATION | FLUORESCENT SENSOR | VISCOSITY DEPENDENCE | LIVING CELLS | REVEALS | ZN2 | Fluorescence | Organic chemistry | Mitochondria | Organelles | Morphology
cellular polarity | cellular microviscosity | mitochondria | fluorescent probes | ORGANELLES | COPPER | MICROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | DEPOLARIZATION | FLUORESCENT SENSOR | VISCOSITY DEPENDENCE | LIVING CELLS | REVEALS | ZN2 | Fluorescence | Organic chemistry | Mitochondria | Organelles | Morphology
Journal Article
Biology of the Cell, ISSN 0248-4900, 11/2018, Volume 110, Issue 11, pp. 249 - 255
An important function of the endoplasmic reticulum (ER) is to serve as a site of secretory protein folding. When the accumulation of misfolded proteins...
ER stress | ER overload | Microviscosity | ROVI | α1‐Antitrypsin | Antitrypsin
ER stress | ER overload | Microviscosity | ROVI | α1‐Antitrypsin | Antitrypsin
Journal Article
Biophysical Journal, ISSN 0006-3495, 05/2019, Volume 116, Issue 9, pp. 1682 - 1691
The dynamics of phosphocholine and maltoside micelles, detergents frequently used for membrane protein structure determination, were investigated using...
EPR SPIN-PROBE | NMR | LIPID-BILAYERS | ACID | BIOPHYSICS | ANGLE X-RAY | LABEL | MICROVISCOSITY | MOLECULAR-DYNAMICS SIMULATIONS | MEMBRANE-PROTEINS | REGION | Detergents, Synthetic
EPR SPIN-PROBE | NMR | LIPID-BILAYERS | ACID | BIOPHYSICS | ANGLE X-RAY | LABEL | MICROVISCOSITY | MOLECULAR-DYNAMICS SIMULATIONS | MEMBRANE-PROTEINS | REGION | Detergents, Synthetic
Journal Article
Wuli Huaxue Xuebao/ Acta Physico - Chimica Sinica, ISSN 1000-6818, 08/2015, Volume 31, Issue 8, pp. 1452 - 1460
Journal Article
The Journal of Physical Chemistry B, ISSN 1520-6106, 12/2018, Volume 122, Issue 49, pp. 11381 - 11389
A protein’s folding or function depends on its mobility through the viscous environment that is defined by the presence of macromolecules throughout the cell....
GREEN FLUORESCENT PROTEIN | MOBILITY | NMR-SPECTROSCOPY | KINETICS | MYOGLOBIN | INTERNAL MICROVISCOSITY | CHEMISTRY, PHYSICAL | CROWDED ENVIRONMENT | ROTATIONAL DIFFUSION | ANISOTROPY | CYTOPLASMIC VISCOSITY
GREEN FLUORESCENT PROTEIN | MOBILITY | NMR-SPECTROSCOPY | KINETICS | MYOGLOBIN | INTERNAL MICROVISCOSITY | CHEMISTRY, PHYSICAL | CROWDED ENVIRONMENT | ROTATIONAL DIFFUSION | ANISOTROPY | CYTOPLASMIC VISCOSITY
Journal Article
Journal of Materials Chemistry B, ISSN 2050-7518, 03/2016, Volume 4, Issue 11, pp. 1968 - 1977
The applications of a bodipy based probe 1 for the identification of diseased cell population out of normal cells on the basis of changes in intracellular...
CELLULAR-VISCOSITY | MATERIALS SCIENCE, BIOMATERIALS | ELECTRON-TRANSFER | DYES | BIOLOGY | SENSOR | MICROVISCOSITY | FLUOROGENS | MOLECULAR ROTOR
CELLULAR-VISCOSITY | MATERIALS SCIENCE, BIOMATERIALS | ELECTRON-TRANSFER | DYES | BIOLOGY | SENSOR | MICROVISCOSITY | FLUOROGENS | MOLECULAR ROTOR
Journal Article
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Full Text
X-linked adrenoleukodystrophy: Clinical, metabolic, genetic and pathophysiological aspects
BBA - Molecular Basis of Disease, ISSN 0925-4439, 09/2012, Volume 1822, Issue 9, pp. 1465 - 1474
X-linked adrenoleukodystrophy (X-ALD) is the most frequent peroxisomal disease. The two main clinical phenotypes of X-ALD are adrenomyeloneuropathy (AMN) and...
Peroxisome | ELOVL1 | ALDP | Leukodystrophy | ABCD1 | VLCFA | BETA-OXIDATION | CEREBRAL ADRENOLEUKODYSTROPHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMBRANE MICROVISCOSITY | CULTURED SKIN FIBROBLASTS | PEROXISOMAL DISORDERS | LONG-CHAIN | BIOPHYSICS | CHAIN FATTY-ACIDS | MOUSE MODEL | ADRENO-LEUKODYSTROPHY | MYELIN PROTEOLIPID PROTEIN | Fatty acids | Genes
Peroxisome | ELOVL1 | ALDP | Leukodystrophy | ABCD1 | VLCFA | BETA-OXIDATION | CEREBRAL ADRENOLEUKODYSTROPHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMBRANE MICROVISCOSITY | CULTURED SKIN FIBROBLASTS | PEROXISOMAL DISORDERS | LONG-CHAIN | BIOPHYSICS | CHAIN FATTY-ACIDS | MOUSE MODEL | ADRENO-LEUKODYSTROPHY | MYELIN PROTEOLIPID PROTEIN | Fatty acids | Genes
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 09/2018, Volume 24, Issue 52, pp. 13706 - 13718
Fluorescent molecular rotors (FMRs) can act as viscosity sensors in various media including subcellular organelles and microfluidic channels. In FMRs, the...
fluorescence dynamics | molecular rotors | fluorescent molecular rotors | microviscosity | viscosity sensors | THIOFLAVIN-T | CELL-MEMBRANE | SENSITIVITY | LIPID-MEMBRANES | LIVE CELLS | CHEMISTRY, MULTIDISCIPLINARY | INTRAMOLECULAR CHARGE-TRANSFER | EXCITED-STATES | IMAGING VISCOSITY | SHEAR-STRESS | PROBE | Fluorescence | Microfluidics | Sensors | Viscosity | Rotors | Chromophores | Derivatives | Organelles
fluorescence dynamics | molecular rotors | fluorescent molecular rotors | microviscosity | viscosity sensors | THIOFLAVIN-T | CELL-MEMBRANE | SENSITIVITY | LIPID-MEMBRANES | LIVE CELLS | CHEMISTRY, MULTIDISCIPLINARY | INTRAMOLECULAR CHARGE-TRANSFER | EXCITED-STATES | IMAGING VISCOSITY | SHEAR-STRESS | PROBE | Fluorescence | Microfluidics | Sensors | Viscosity | Rotors | Chromophores | Derivatives | Organelles
Journal Article
Tetrahedron, ISSN 0040-4020, 01/2019, Volume 75, Issue 2, pp. 129 - 136
The mechanism of chiral bisphosphine iron-catalyzed C(sp )-C(sp ) cross-coupling reactions has been studied via the synthesis of novel radical-clock...
Mechanisms | DFT | Cross-coupling reactions | Bisphosphine-iron | Tandem cyclization-arylation reactions | PALLADIUM | REAGENTS | ENANTIOSELECTIVE SYNTHESIS | REACTIVITY | CHEMISTRY, ORGANIC | MICROVISCOSITY | ALKYL-HALIDES | RECOMBINATION EFFICIENCIES | BENZYL | LIGAND | DENSITY-FUNCTIONAL THEORY
Mechanisms | DFT | Cross-coupling reactions | Bisphosphine-iron | Tandem cyclization-arylation reactions | PALLADIUM | REAGENTS | ENANTIOSELECTIVE SYNTHESIS | REACTIVITY | CHEMISTRY, ORGANIC | MICROVISCOSITY | ALKYL-HALIDES | RECOMBINATION EFFICIENCIES | BENZYL | LIGAND | DENSITY-FUNCTIONAL THEORY
Journal Article
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, 01/2017, Volume 170, pp. 150 - 156
Organogels prepared from AOT/4-chlorophenol/m-xylene are immobile in the macroscopic sense, with a well-characterized internal structure. However, the...
Solvent relaxation | Microviscosity | Organogel | POLAR | SPECTROSCOPY | PHOTOISOMERIZATION | SOLVATION DYNAMICS | MICELLES | FEMTOSECOND | MICROSTRUCTURE | DCM
Solvent relaxation | Microviscosity | Organogel | POLAR | SPECTROSCOPY | PHOTOISOMERIZATION | SOLVATION DYNAMICS | MICELLES | FEMTOSECOND | MICROSTRUCTURE | DCM
Journal Article
Chemical Physics Letters, ISSN 0009-2614, 11/2019, Volume 735, p. 136754
Specific interaction of the chloride and perchlorate ions with F127 hydrogel is studied by fluorescence correlation spectroscopy and picoseconds dynamics. An...
Polymer hydrogel | Solvation | Specific ion effect | Micro-viscosity | FCS | BLOCK-COPOLYMERS | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | MICROVISCOSITY | GELATION | PEO TRIBLOCK COPOLYMER | HYDRATION | HOFMEISTER ANIONS | COUMARIN-153
Polymer hydrogel | Solvation | Specific ion effect | Micro-viscosity | FCS | BLOCK-COPOLYMERS | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | MICROVISCOSITY | GELATION | PEO TRIBLOCK COPOLYMER | HYDRATION | HOFMEISTER ANIONS | COUMARIN-153