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Clinical pharmacology and therapeutics, ISSN 1532-6535, 2014, Volume 96, Issue 3, pp. 349 - 359
.... It is therefore important to precisely and reliably evaluate their in vivo activity (phenotyping). A cocktail approach involving the administration of multiple CYP‐ or P‐gp... 
P4502B6 ACTIVITY | VORICONAZOLE | LC-MS/MS | SINGLE-POINT | ORAL MIDAZOLAM | VOLUNTEERS | IN-VIVO | PHARMACOLOGY & PHARMACY | DRUG-METABOLIZING-ENZYMES | KAROLINSKA COCKTAIL | BUPROPION HYDROXYLATION | Predictive Value of Tests | Pharmaceutical Preparations - blood | Caffeine - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Dried Blood Spot Testing | Humans | Omeprazole - blood | Bupropion - blood | Midazolam - administration & dosage | Substrate Specificity | Male | Chromatography, High Pressure Liquid | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Coffee | Terfenadine - administration & dosage | Caffeine - pharmacokinetics | Feasibility Studies | Enzyme Inhibitors - administration & dosage | Young Adult | Chromatography, Reverse-Phase | Tandem Mass Spectrometry | Capsules | Spectrometry, Mass, Electrospray Ionization | Flurbiprofen - administration & dosage | Adult | Dextromethorphan - pharmacokinetics | Terfenadine - blood | ATP-Binding Cassette, Sub-Family B, Member 1 - blood | Pharmaceutical Preparations - administration & dosage | Terfenadine - pharmacokinetics | Bupropion - pharmacokinetics | Flurbiprofen - pharmacokinetics | Cytochrome P-450 Enzyme System - blood | Administration, Oral | Isoenzymes | Caffeine - blood | Omeprazole - administration & dosage | Terfenadine - analogs & derivatives | Omeprazole - pharmacokinetics | Carbonated Beverages | Midazolam - pharmacokinetics | Bupropion - administration & dosage | Dextromethorphan - blood | Flurbiprofen - blood | Phenotype | Pilot Projects | Midazolam - blood | Dextromethorphan - administration & dosage | Usage | Glycoproteins | Liquid chromatography | Research | Pharmacokinetics | Cytochrome P-450 | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of emergency medicine, ISSN 0736-4679, 2017, Volume 53, Issue 1, pp. 38 - 48
Abstract Background Intranasal (IN) medication delivery is a viable alternative to other routes of administration, including intravenous (IV) and intramuscular (IM) administration... 
Emergency | nasal | intranasal | medication | prehospital | emergency department | RECTAL DIAZEPAM | STATUS EPILEPTICUS | LACERATION REPAIR | RANDOMIZED CONTROLLED-TRIAL | PROCEDURAL SEDATION | POSTOPERATIVE PAIN MANAGEMENT | ACUTE SEIZURES | EMERGENCY MEDICINE | DOUBLE-BLIND | OPIOID OVERDOSE | INTRAVENOUS LORAZEPAM | Fentanyl - administration & dosage | Anesthetics, Dissociative - therapeutic use | Emergency Service, Hospital - trends | Narcotic Antagonists - administration & dosage | Fentanyl - therapeutic use | Humans | Hypnotics and Sedatives - administration & dosage | Haloperidol - administration & dosage | Midazolam - administration & dosage | Anticonvulsants - administration & dosage | Narcotics - therapeutic use | Antidotes - administration & dosage | Hypnotics and Sedatives - therapeutic use | Ketamine - administration & dosage | Lorazepam - therapeutic use | Administration, Intranasal - methods | Antipsychotic Agents - therapeutic use | Emergency Service, Hospital - organization & administration | Flumazenil - administration & dosage | Midazolam - therapeutic use | Ketamine - therapeutic use | Dexmedetomidine - administration & dosage | Dexmedetomidine - therapeutic use | Anesthetics, Dissociative - administration & dosage | Anticonvulsants - therapeutic use | Haloperidol - therapeutic use | Naloxone - therapeutic use | Lorazepam - administration & dosage | Antipsychotic Agents - administration & dosage | Flumazenil - therapeutic use | Hydromorphone - administration & dosage | Narcotics - administration & dosage | Narcotic Antagonists - therapeutic use | Hydromorphone - therapeutic use | Naloxone - administration & dosage | Antidotes - therapeutic use | Drugs | Usage | Emergency service | Hospitals | Emergency medicine
Journal Article
British journal of clinical pharmacology, ISSN 0306-5251, 2013, Volume 76, Issue 3, pp. 455 - 466
.../2J2 , P ‐gp and Bcrp ( ABCG2 ). However, the pharmacokinetic effects and implications of the co‐administration of rivaroxaban and medications that interfere... 
P‐glycoprotein | rivaroxaban | drug interactions | cytochrome P450 | healthy subjects | P-glycoprotein | Rivaroxaban | Healthy subjects | Cytochrome P450 | Drug interactions | BAY-59-7939 | SAFETY | PREVENTION | PHARMACODYNAMICS | PROTEASE INHIBITORS | IN-VITRO | FACTOR-XA INHIBITOR | ERYTHROMYCIN | PHARMACOLOGY & PHARMACY | LIVER-MICROSOMES | Anticoagulants - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Erythromycin - pharmacology | Ketoconazole - administration & dosage | Humans | Middle Aged | Cytochrome P-450 Enzyme System - metabolism | Midazolam - administration & dosage | Substrate Specificity | Metabolic Clearance Rate | Thiophenes - administration & dosage | Ketoconazole - pharmacology | Enzyme Inhibitors - administration & dosage | Young Adult | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Clarithromycin - pharmacokinetics | Clarithromycin - administration & dosage | Adult | Morpholines - administration & dosage | Enzyme Inhibitors - pharmacology | Ketoconazole - pharmacokinetics | Midazolam - pharmacokinetics | Cytochrome P-450 CYP3A - administration & dosage | Erythromycin - administration & dosage | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Thiophenes - pharmacokinetics | Erythromycin - pharmacokinetics | Cytochrome P-450 CYP3A - metabolism | Adolescent | Anticoagulants - pharmacokinetics | Morpholines - pharmacokinetics | Clarithromycin - pharmacology | Midazolam - pharmacology | Ketoconazole | Protease inhibitors | Fluconazole | Proteases | Cytochrome P-450 | Dosage and administration | Anticoagulants (Medicine) | Erythromycin | Thromboembolism
Journal Article
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2009, Volume 68, Issue 6, pp. 928 - 935
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Numerous cocktails using concurrent administration of several cytochrome P450 (CYP... 
in vivo drug-drug interaction | cocktail | CYP | in vivo drug–drug interaction | Cocktail | In vivo drug-drug interaction | DRUG | CAFFEINE | COMBINED PHENOTYPIC ASSESSMENT | METOPROLOL | OMEPRAZOLE TREATMENT | XANTHINE-OXIDASE | METABOLISM | ENZYMES | IN-VIVO | N-ACETYLTRANSFERASE-2 | PHARMACOLOGY & PHARMACY | Anti-Anxiety Agents - administration & dosage | Caffeine - administration & dosage | Anticoagulants - administration & dosage | Area Under Curve | Humans | Midazolam - administration & dosage | Cytochrome P-450 CYP1A2 - administration & dosage | Male | Metabolic Clearance Rate | Warfarin - administration & dosage | Caffeine - pharmacokinetics | Anti-Ulcer Agents - pharmacokinetics | Young Adult | Anti-Anxiety Agents - pharmacokinetics | Drug Interactions | Adult | Drug Therapy, Combination | Administration, Oral | Omeprazole - administration & dosage | Omeprazole - pharmacokinetics | Midazolam - pharmacokinetics | Anti-Ulcer Agents - administration & dosage | Central Nervous System Stimulants - pharmacokinetics | Anticoagulants - pharmacokinetics | Central Nervous System Stimulants - administration & dosage | Drug Combinations | Cytochrome P-450 CYP1A2 - pharmacokinetics | Omeprazole | Warfarin | Analysis | Drug interactions | Cytochrome P-450 | Physiological aspects | Liquid chromatography | Mass spectrometry | Caffeine | Drug Metabolism
Journal Article
Cochrane library, ISSN 1465-1858, 2018, Volume 2018, Issue 12, p. CD003877
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 2006, Volume 80, Issue 3, pp. 203 - 215
Journal Article