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Life Sciences, ISSN 0024-3205, 07/2011, Volume 89, Issue 1-2, pp. 57 - 64
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 57, Issue 3, pp. 628 - 636
Journal Article
Clinical pharmacokinetics, ISSN 0312-5963, 2017, Volume 56, Issue 10, pp. 1231 - 1244
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2007, Volume 35, Issue 11, pp. 2119 - 2126
Predicting drug-drug interactions requires an assessment of the drug concentration available to the enzyme active site, both in vivo, and within an in vitro... 
Tolbutamide - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 CYP3A | Microsomes, Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Male | Fluconazole - metabolism | Quinine - pharmacology | Microsomes, Liver - enzymology | Tolbutamide - metabolism | Fluoxetine - pharmacology | Dextromethorphan - pharmacology | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Fluvoxamine - pharmacokinetics | Ketoconazole - pharmacokinetics | Rats | Rats, Sprague-Dawley | Catalysis - drug effects | Miconazole - pharmacokinetics | Miconazole - pharmacology | Fluoxetine - metabolism | Cytochrome P-450 CYP2D6 - metabolism | Kinetics | Midazolam - pharmacology | Hepatocytes - enzymology | Cytochrome P-450 CYP2D6 Inhibitors | Quinine - pharmacokinetics | Fluconazole - pharmacology | Tolbutamide - pharmacokinetics | Fluoxetine - pharmacokinetics | Ketoconazole - metabolism | Hepatocytes - metabolism | Ketoconazole - pharmacology | Hepatocytes - cytology | Enzyme Inhibitors - pharmacokinetics | Phenytoin - pharmacology | Dextromethorphan - pharmacokinetics | Phenytoin - metabolism | Quinine - metabolism | Fluvoxamine - metabolism | Cells, Cultured | Midazolam - pharmacokinetics | Fluvoxamine - pharmacology | Miconazole - metabolism | Fluconazole - pharmacokinetics | Animals | Midazolam - metabolism | Phenytoin - pharmacokinetics
Journal Article
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 08/2018, Volume 40, Issue 8, pp. 1322 - 1337
Red ginseng is one of the world's most popular herbal medicines; it exhibits a wide range of pharmacologic activities and is often co-ingested with other... 
pharmacokinetics | cytochrome P450 | red ginseng | drug interaction | OATP1B1 | CYTOCHROME-P450 | PANAX-GINSENG | TRANSPORTERS | DISPOSITION | COCKTAIL APPROACH | DISEASES | ENZYMES | PHARMACOLOGY & PHARMACY | GINSENOSIDES | EXTRACT | Caffeine - metabolism | Panax | Omeprazole - metabolism | Humans | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Male | Omeprazole - pharmacokinetics | Losartan - metabolism | Random Allocation | Midazolam - pharmacokinetics | Cytochrome P-450 CYP1A2 - metabolism | Caffeine - pharmacokinetics | Liver-Specific Organic Anion Transporter 1 - metabolism | Young Adult | Drug Interactions | Cytochrome P-450 CYP3A - metabolism | Plant Preparations - pharmacology | Cytochrome P-450 CYP2D6 - metabolism | Midazolam - metabolism | Adult | Cytochrome P-450 CYP2C19 - metabolism | Dextromethorphan - pharmacokinetics | Losartan - pharmacokinetics | Medical research | Medicine, Botanic | Analysis | Drug interactions | Cytochrome P-450 | Medicine, Experimental | Medicine, Herbal | Cytochrome | Laboratories | Liver | Dextromethorphan | Hepatitis | Metabolites | Cryopreservation | Trademarks | Drug interaction | Drug dosages | CYP2D6 protein | Caffeine | Enzymes | Cytochrome P450 | Pharmacology | CYP1A2 protein | Substrates | Catheters | Microsomes | Omeprazole | Herbal medicine | Organic anion transporting polypeptide | Hepatocytes | Cytochromes | In vivo methods and tests | Midazolam | Ginseng | Transporter
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2008, Volume 107, Issue 5, pp. 1358 - 1368
The human brain endothelial capillary cell line hCMEC/D3 has been developed recently as a model for the human blood‐brain barrier. In this study a further... 
transendothelial transport | p‐glycoprotein | blood‐brain barrier | ABCB1 | permeability | ABCG2 | p-glycoprotein | Transendothelial transport | Permeability | Blood-brain barrier | blood-brain barrier | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | MICROVESSEL ENDOTHELIUM | TRANSFERRIN RECEPTOR | IN-VITRO MODEL | SITES | MULTIDRUG-RESISTANCE | ASTROCYTIC FACTORS | EXPRESSION | CULTURE MODEL | CANCER RESISTANCE PROTEIN | Flow Cytometry - methods | Humans | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Brain - blood supply | ATP-Binding Cassette Transporters - genetics | Biological Transport | Sucrose - metabolism | ATP-Binding Cassette Transporters - metabolism | Multidrug Resistance-Associated Proteins - genetics | Receptors, Transferrin - genetics | Neoplasm Proteins - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Cell Line | Brain - cytology | Endothelial Cells - metabolism | RNA, Messenger - genetics | Receptors, Transferrin - metabolism | ATP Binding Cassette Transporter, Subfamily B | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | Blood-Brain Barrier - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Analysis of Variance | Endothelial Cells - cytology | Midazolam - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Proteins | Propranolol hydrochloride | Medical colleges | Brain | Transferrin | Messenger RNA | Analysis | Morphine | Oligosaccharides | Endothelium | Dyes and dyeing | Neurology | Cell culture | Biochemistry | Pharmacology
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