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Cell Stem Cell, ISSN 1934-5909, 01/2017, Volume 20, Issue 1, pp. 135 - 148
Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. Most of the approaches currently under development involve... 
Parkinson's disease | good manufacturing practice | MHB | GMP | STN | diencephalon | FGF8 | ventral midbrain | subthalamic nucleus | dopaminergic neurons | transplantation | VM | midbrain-hindbrain boundary | hESCs | human embryonic stem cells | PROGENITORS | EMBRYONIC STEM-CELLS | MOUSE | MIDBRAIN DOPAMINE NEURONS | GENERATION | SPECIFICATION | MODEL | MORPHOLOGY | BRAIN | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Laminin - pharmacology | Parkinson Disease - therapy | Human Embryonic Stem Cells - transplantation | Mesencephalon - metabolism | Human Embryonic Stem Cells - cytology | Humans | Extracellular Matrix - metabolism | Subthalamic Nucleus - metabolism | Cell Lineage - drug effects | Subthalamic Nucleus - cytology | Dopaminergic Neurons - cytology | Stem Cell Transplantation | Fibroblast Growth Factor 8 - metabolism | Time Factors | Human Embryonic Stem Cells - drug effects | Dopaminergic Neurons - metabolism | Dopaminergic Neurons - drug effects | Female | Dopamine - metabolism | Biomarkers - metabolism | Reproducibility of Results | Extracellular Matrix - drug effects | Translational Medical Research | Cells, Cultured | Treatment Outcome | Rats, Sprague-Dawley | Animals | Sequence Analysis, RNA | Cell Differentiation - drug effects | Index Medicus | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Neurovetenskaper | Basic Medicine | Neurologi | Clinical Medicine | Neurology | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Journal of the Neurological Sciences, ISSN 0022-510X, 09/2019, Volume 404, pp. 40 - 43
Journal Article
Parkinsonism & Related Disorders, ISSN 1353-8020, 07/2019
INTRODUCTIONIn the present study, midbrain atrophy and the pons-to-midbrain area ratio (P/M ratio) were investigated as diagnostic markers for presymptomatic... 
Journal Article
Brain Structure and Function, ISSN 1863-2653, 1/2016, Volume 221, Issue 1, pp. 535 - 561
Journal Article
06/2012
Perturbations of the complex intrinsic and extrinsic factors that contribute to cellular differentiation can have many consequences ranging from... 
0379 | Histone deacetylase inhibitors | mammalian midbrain | 0307 | 0317
Dissertation
Journal Article
Clinical Imaging, ISSN 0899-7071, 11/2019, Volume 58, pp. 170 - 176
In a recent study, it was found that, although intrinsic midbrain signal abnormality (IMSA) on MRI is associated with Parinaud's syndrome (PS) in patients with... 
Dorsal midbrain syndrome | Pineal mass | Hydrocephalus | Parinaud's syndrome | Intrinsic midbrain signal | Index Medicus
Journal Article
Cell Stem Cell, ISSN 1934-5909, 2011, Volume 8, Issue 3, pp. 267 - 280
Studies of Parkinson's disease (PD) have been hindered by lack of access to affected human dopaminergic (DA) neurons. Here, we report generation of induced... 
PLURIPOTENT STEM-CELLS | KINASE-ACTIVITY | ALZHEIMERS-DISEASE | ANIMAL-MODELS | HUMAN FIBROBLASTS | ALPHA-SYNUCLEIN | LEWY-BODY-DISEASE | SUBSTANTIA-NIGRA | MIDBRAIN DOPAMINERGIC-NEURONS | PARKINSONS-DISEASE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neurons - pathology | Humans | Middle Aged | rho-Associated Kinases - antagonists & inhibitors | Amino Acid Substitution - drug effects | Oxidopamine - pharmacology | rho-Associated Kinases - metabolism | Female | Cell Death - drug effects | Neurons - drug effects | Dopamine - metabolism | Protein-Serine-Threonine Kinases - metabolism | Induced Pluripotent Stem Cells - metabolism | Mesencephalon - pathology | Amides - pharmacology | Induced Pluripotent Stem Cells - pathology | Parkinson Disease - pathology | Induced Pluripotent Stem Cells - drug effects | Hydrogen Peroxide - pharmacology | Protein-Serine-Threonine Kinases - genetics | Parkinson Disease - genetics | Mutation - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Leupeptins - pharmacology | Phenotype | Animals | Cell Differentiation - drug effects | Parkinson Disease - enzymology | Mice | Pyridines - pharmacology | Oxidative Stress - drug effects | Index Medicus | α-synuclein(SNCA) | 6-hydroxydopamine | p.G2019S | hydrogen peroxide | Leucine Rich Repeat Kinase 2 (LRRK2) | human embryonic stem cells (hESCs) | induced pluripotent stem cells (iPSCs) | midbrain dopaminergic neurons (mDA) | Parkinson’s disease | MG-132
Journal Article
12/2011
Rosette-forming glioneuronal tumor, a mixed glial and neuronal tumor, is a relatively new entity in tumors of the central nervous system, included in 2007... 
midbrain and suprasellar location | rosette-forming | Glioneuronal tumor
Web Resource
Brainstem gliomas – A clinicopathological study of 45 cases with p53 immunohistochemistry, 10/2004
BACKGROUND: Brainstem tumors represent 10% of central nervous system tumors, accounting for 30% of pediatric posterior fossa tumors. AIMS: The aim of this... 
p53, brainstem, astrocytoma, glioblastoma multiforme, pons, midbrain, medulla, gliomas. cn04033 | Botany
Journal
Journal of neurophysiology, ISSN 0022-3077, 06/2019, Volume 121, Issue 6, pp. 2126 - 2139
The inferior colliculus (IC) is a large midbrain nucleus that integrates inputs from many auditory brainstem and cortical structures. Despite its prominent... 
auditory midbrain | GABA | inferior colliculus | glutamate | HCN channels
Journal Article
Journal Article
03/2008
Cyclopentolate is a synthetic anti-cholinergic agent widely used in ophthalmology clinics. It can cause cardiovascular side-effects such as hypertension,... 
midbrain hemorrhage | systemic anticholinergic toxicity | Cyclopentolate
Web Resource
Scientific Reports, ISSN 2045-2322, 08/2016, Volume 6, Issue 1, pp. 31380 - 31380
GBA gene mutations are the greatest cause of Parkinson disease (PD). GBA encodes the lysosomal enzyme glucocerebrosidase (GCase) but the mechanisms by which... 
UNFOLDED PROTEIN RESPONSE | CA2+ STORES | DROSOPHILA MODEL | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | MIDBRAIN DOPAMINE NEURONS | ENDOPLASMIC-RETICULUM | ALPHA-SYNUCLEIN | GLUCOCEREBROSIDASE MUTATIONS | GAUCHER-DISEASE | LYSOSOMAL BIOGENESIS | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2006, Volume 103, Issue 4, pp. 1059 - 1064
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 12/2017, Volume 174, Issue 24, pp. 4725 - 4737
BACKGROUND AND PURPOSE Vasoactive intestinal peptide (VIP) is an important modulator of hippocampal synaptic transmission that influences both GABAergic... 
MIDBRAIN DOPAMINERGIC NEURON | CONCISE GUIDE | EMBRYONIC STEM-CELLS | IN-VIVO | CATENIN | PHARMACOLOGY & PHARMACY | VENTRAL MIDBRAIN | INT-1 PROTOONCOGENE | SYNTHASE KINASE 3 | PARKINSONS-DISEASE | TRANSPLANTATION
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 03/2018, Volume 119, Issue 3, pp. 1235 - 1247
Journal Article
Neuroscience, ISSN 0306-4522, 05/2018, Volume 379, pp. 302 - 315
Phosphorylation of α-synuclein at serine 129 (P-Ser 129 α-syn) is involved in the pathogenesis of Parkinson’s disease (PD) and Lewy body (LB) formation.... 
pathogenesis | neocortex | midbrain | MPTP | phosphorylated α-synuclein | Parkinson’s disease
Journal Article
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