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Journal Article
Trends in Microbiology, ISSN 0966-842X, 2016, Volume 24, Issue 6, pp. 490 - 502
Human coronaviruses (HCoVs) were first described in the 1960s for patients with the common cold. Since then, more HCoVs have been discovered, including those... 
Internal Medicine | pathogenesis | coronavirus | SARS | recombination | evolution | MERS | Evolution | Recombination | Coronavirus | Pathogenesis | NATURAL RECOMBINATION | MOUSE HEPATITIS-VIRUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SARS CORONAVIRUS | INTESTINAL CELL INTERACTIONS | MICROBIOLOGY | TRANSMISSIBLE GASTROENTERITIS | CLINICAL-FEATURES | HONG-KONG | RESPIRATORY-SYNDROME CORONAVIRUS | SAUDI-ARABIA | ORGAN-CULTURES | Coronavirus - classification | Severe Acute Respiratory Syndrome - epidemiology | Humans | Severe Acute Respiratory Syndrome - transmission | Phylogeny | Coronavirus Infections - transmission | SARS Virus - genetics | Coronavirus Infections - epidemiology | Disease Outbreaks | Recombination, Genetic | Cross Infection - virology | Republic of Korea - epidemiology | Saudi Arabia - epidemiology | Cross Infection - epidemiology | Coronavirus - pathogenicity | Ecology | SARS Virus - pathogenicity | Middle East - epidemiology | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Coronavirus Infections - virology | Middle East Respiratory Syndrome Coronavirus - genetics | Respiratory Tract Diseases - epidemiology | Coronavirus - genetics | Respiratory Tract Diseases - virology | Evolution, Molecular | Virus diseases | Genetic research | Health aspects | Epidemiology | Lung diseases | Severe acute respiratory syndrome | Resveratrol
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 09/2014, Volume 16, Issue 3, pp. 328 - 337
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19403 - 19422
All coronaviruses, including the recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) from the beta-CoV subgroup, require the proteolytic... 
DIMER INTERFACE | DESIGN | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGICAL EVALUATION | MAIN PROTEASE | DIFFRACTION DATA | INHIBITORS | CATALYTIC-ACTIVITY | 3C-LIKE PROTEASE | SARS-CORONAVIRUS | Cysteine Endopeptidases - chemistry | Peptidomimetics - chemical synthesis | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Viral Proteins - metabolism | Cysteine Endopeptidases - metabolism | Antiviral Agents - chemistry | Escherichia coli - metabolism | Middle East Respiratory Syndrome Coronavirus - enzymology | Recombinant Proteins - metabolism | Amino Acid Sequence | Antiviral Agents - pharmacology | Gene Expression | Peptidomimetics - pharmacology | Viral Proteins - chemistry | Middle East Respiratory Syndrome Coronavirus - drug effects | Recombinant Proteins - chemistry | Viral Proteins - genetics | Viral Proteins - antagonists & inhibitors | Peptidomimetics - chemistry | Recombinant Proteins - genetics | Sequence Alignment | Escherichia coli - genetics | Middle East Respiratory Syndrome Coronavirus - genetics | Cysteine Endopeptidases - genetics | Antiviral Agents - chemical synthesis | Hydrophobic and Hydrophilic Interactions | Ligands | Molecular Docking Simulation | Kinetics | Protein Multimerization - drug effects | viral protease | X-ray crystallography | Protein Structure and Folding | analytical ultracentrifugation | monomer-dimer equilibrium | enzyme inhibitor | ligand-induced dimerization | β-CoV | enzyme inactivation | MERS-CoV 3CLpro | enzyme kinetics
Journal Article
Journal Article
Science, ISSN 0036-8075, 01/2016, Volume 351, Issue 6268, pp. 81 - 84
Journal Article
Journal Article
Journal of Virology, ISSN 0022-538X, 2017, Volume 91, Issue 1
Middle East respiratory syndrome coronavirus (MERS-CoV) is an important emerging pathogen that was first described in 2012. While the cell surface receptor for... 
DPP4 | Coronavirus | Immune response | Viral pathogenesis | Pathogenesis | MERS-CoV | Mouse model | MERS | ANTIBODIES | mouse model | coronavirus | SYNDROME CORONAVIRUS INFECTION | INDUCTION | PNEUMONIA | viral pathogenesis | pathogenesis | REPLICATION | VIROLOGY | immune response | MICE | GENERATION | FUNCTIONAL RECEPTOR | EXPRESSION | DIPEPTIDYL PEPTIDASE 4 | Humans | Transcriptome | Gene Expression Profiling | Lymphocyte Depletion | Receptors, Virus - genetics | Middle East Respiratory Syndrome Coronavirus - immunology | Virus Internalization | CD4-Positive T-Lymphocytes - immunology | Lung - virology | Macrophages - virology | CD4-Positive T-Lymphocytes - virology | Transgenes | Dipeptidyl Peptidase 4 - immunology | Macrophages - immunology | Disease Models, Animal | Promoter Regions, Genetic | Mice, Inbred C57BL | Gene Expression Regulation | Coronavirus Infections - genetics | Dipeptidyl Peptidase 4 - genetics | Mice, Transgenic | Coronavirus Infections - immunology | Host-Pathogen Interactions | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Animals | Coronavirus Infections - virology | Virus Replication | CD8-Positive T-Lymphocytes - virology | Middle East Respiratory Syndrome Coronavirus - genetics | Coronavirus Infections - pathology | Receptors, Virus - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Lung - immunology
Journal Article