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1. Full Text Middle East Respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease
by Chan, Jasper F. W and Lau, Susanna K. P and To, Kelvin K. W and Cheng, Vincent C. C and Woo, Patrick C. Y and Yue, Kwok-Yung
Clinical Microbiology Reviews, ISSN 0893-8512, 2015, Volume 28, Issue 2, pp. 465 - 522
The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife market civets and ultimately to bats. Subsequent hunting for novel... 
PUBLIC-HEALTH RESPONSE | COMMUNITY-ACQUIRED PNEUMONIA | SYNDROME MERS CORONAVIRUS | INNATE ANTIVIRAL RESPONSE | PAPAIN-LIKE PROTEASE | MICROBIOLOGY | INFLUENZA-A H7N9 | PIPISTRELLUS BAT CORONAVIRUS | CRITICALLY-ILL PATIENTS | RECEPTOR-BINDING DOMAIN | DIPEPTIDYL PEPTIDASE 4 | Middle East Respiratory Syndrome Coronavirus - classification | Antiviral Agents - therapeutic use | Humans | Infection Control | Zoonoses - therapy | Zoonoses - transmission | Zoonoses - virology | Coronavirus Infections - transmission | Zoonoses - pathology | Animals | Coronavirus Infections - epidemiology | Coronavirus Infections - virology | Coronavirus Infections - therapy | Zoonoses - epidemiology | Coronavirus Infections - pathology | Middle East Respiratory Syndrome Coronavirus - physiology | Disease Models, Animal | Reviews
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2. Full Text Middle East Respiratory Syndrome
by Arabi, Yaseen M and Balkhy, Hanan H and Hayden, Frederick G and Bouchama, Abderrezak and Luke, Thomas and Baillie, J. Kenneth and Al-Omari, Awad and Hajeer, Ali H and Senga, Mikiko and Denison, Mark R and Nguyen-Van-Tam, Jonathan S and Shindo, Nahoko and Bermingham, Alison and Chappell, James D and Van Kerkhove, Maria D and Fowler, Robert A
The New England Journal of Medicine, ISSN 0028-4793, 02/2017, Volume 376, Issue 6, pp. 584 - 594
The Middle East respiratory syndrome is caused by a coronavirus that was first identified in Saudi Arabia in 2012. Periodic outbreaks continue to occur in the... 
BROAD-SPECTRUM | MEDICINE, GENERAL & INTERNAL | TRANSMISSION | ACCESSORY PROTEINS | MOUSE MODEL | CORONAVIRUS MERS-COV | INFECTION | RIBAVIRIN | OUTBREAK | PNEUMONIA | SAUDI-ARABIA | Coronavirus Infections - transmission | Middle East | Animals | Coronavirus Infections - epidemiology | Coronavirus Infections - diagnosis | Coronavirus Infections - therapy | Humans | Risk Factors | Disease Transmission, Infectious | Middle East Respiratory Syndrome Coronavirus - physiology | Disease Models, Animal | Epidemiology | Control | Studies | Outbreaks | Infections | Laboratories | Respiratory diseases
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3. Full Text SARS and MERS: Recent insights into emerging coronaviruses
by De Wit, Emmie and Van Doremalen, Neeltje and Falzarano, Darryl and Munster, Vincent J
Nature Reviews Microbiology, ISSN 1740-1526, 08/2016, Volume 14, Issue 8, pp. 523 - 534
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronavirus into the... 
VIRAL LOAD | SYNERGISTICALLY INHIBIT | NEUTRALIZING ANTIBODIES | COV INFECTION | POSTEXPOSURE EFFICACY | RESPIRATORY SYNDROME-CORONAVIRUS | PAPAIN-LIKE PROTEASE | HUMAN MONOCLONAL-ANTIBODY | MICROBIOLOGY | CLINICAL-FEATURES | RECEPTOR-BINDING DOMAIN | Middle East Respiratory Syndrome Coronavirus - ultrastructure | Severe Acute Respiratory Syndrome - virology | Humans | Pandemics - prevention & control | Severe Acute Respiratory Syndrome - transmission | Severe Acute Respiratory Syndrome - immunology | Cross Infection | Coronavirus Infections - immunology | SARS Virus - pathogenicity | Coronavirus Infections - transmission | SARS Virus - ultrastructure | Camelus - virology | Travel | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Animals | Immune Evasion | Communicable Diseases, Emerging - prevention & control | Coronavirus Infections - virology | Virus Replication | Coronavirus Infections - therapy | Disease Outbreaks - prevention & control | SARS Virus - physiology | Communicable Diseases, Emerging - virology | Middle East Respiratory Syndrome Coronavirus - physiology | Evaluation | Medical research | Care and treatment | Severe acute respiratory syndrome | Medicine, Experimental | Development and progression | Infection control
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4. Full Text Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
by Dyall, Julie and Coleman, Christopher M and Hart, Brit J and Venkataraman, Thiagarajan and Holbrook, Michael R and Kindrachuk, Jason and Johnson, Reed F and Olinger Jr, Gene G and Jahrling, Peter B and Laidlaw, Monique and Johansen, Lisa M and Lear-Rooney, Calli M and Glass, Pamela J and Hensley, Lisa E and Frieman, Matthew B
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 2014, Volume 58, Issue 8, pp. 4885 - 4893
Outbreaks of emerging infections present health professionals with the unique challenge of trying to select appropriate pharmacologic treatments in the clinic... 
BATS | CELLS | MONENSIN | VIRUS | REPLICATION | ENTRY | CHLORPROMAZINE | RECEPTOR | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | MERS-COV | INHIBITORS | Small Molecule Libraries - pharmacology | Virus Replication - drug effects | Antiviral Agents - pharmacology | Humans | Cercopithecus aethiops | Middle East Respiratory Syndrome Coronavirus - drug effects | SARS Virus - drug effects | Estrogen Antagonists - pharmacology | Drug Approval | Drug Repositioning | Animals | High-Throughput Screening Assays | Inhibitory Concentration 50 | SARS Virus - physiology | Antipsychotic Agents - pharmacology | Vero Cells | Middle East Respiratory Syndrome Coronavirus - physiology | Antiviral Agents
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5. Full Text Generation of a transgenic mouse model of middle east respiratory syndrome coronavirus infection and disease
by Agrawal, Anurodh Shankar and Garron, Tania and Tao, Xinrong and Peng, Bi-Hung and Wakamiya, Maki and Chan, Teh-Sheng and Couch, Robert B and Tseng, Chien-Te K
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 7, pp. 3659 - 3670
The emergence of Middle East respiratory syndrome-coronavirus (MERS-CoV) in the Middle East since 2012 has caused more than 900 human infections with similar... 
PATHOGENESIS | PEPTIDASE-IV | REPLICATION | INHIBITION | TROPISM | VIRUS | VIROLOGY | MICE | INDUCTION | EXPRESSION | SARS-CORONAVIRUS | Gene Expression | Dipeptidyl Peptidase 4 - biosynthesis | Humans | Dipeptidyl Peptidase 4 - genetics | Mice, Transgenic | Viral Load | Animals | Animal Structures - virology | Coronavirus Infections - virology | Time Factors | Coronavirus Infections - pathology | Middle East Respiratory Syndrome Coronavirus - physiology | Disease Models, Animal
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6. Full Text Further evidence for bats as the evolutionary source of middle east respiratory syndrome coronavirus
by Anthony, S.J and Gilardi, K and Menachery, V.D and Goldstein, T and Ssebide, B and Mbabazi, R and Navarrete-Macias, I and Liang, E and Wells, H and Hicks, A and Petrosov, A and Byarugaba, D.K and Debbink, K and Dinnon, K.H and Scobey, T and Randell, S.H and Yount, B.L and Cranfield, M and Johnson, C.K and Baric, R.S and Lipkin, W.I and Mazet, J.A.K
mBio, ISSN 2161-2129, 03/2017, Volume 8, Issue 2, p. e00373-17
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unknown. Current evidence suggests that insectivorous bats are... 
Spike | Uganda | Bat | MERS coronavirus | Zoonoses | ANTIBODIES | PROTEIN | zoonoses | RECEPTOR | MICROBIOLOGY | TO-HUMAN TRANSMISSION | COV | spike | DROMEDARY CAMELS | GROUP C BETACORONAVIRUS | SARS-LIKE CORONAVIRUS | bat | DIPEPTIDYL PEPTIDASE 4 | Genome, Viral | Middle East Respiratory Syndrome Coronavirus - classification | Chiroptera - virology | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Receptors, Virus - metabolism | Synteny | Phylogeny | Animals | Middle East Respiratory Syndrome Coronavirus - genetics | Middle East Respiratory Syndrome Coronavirus - isolation & purification | Virus Attachment | Middle East Respiratory Syndrome Coronavirus - physiology | Evolution, Molecular
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7. Full Text Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia
by Sabir, Jamal S.M and Lam, Tommy T.-Y and Ahmed, Mohamed M.M and Li, Lifeng and Shen, Yongyi and Abo-Aba, Salah E.M and Qureshi, Muhammad I and Abu-Zeid, Mohamed and Zhang, Yu and Khiyami, Mohammad A and Alharbi, Njud S and Hajrah, Nahid H and Sabir, Meshaal J and Mutwakil, Mohammed H.Z and Kabli, Saleh A and Alsulaimany, Faten A.S and Obaid, Abdullah Y and Zhou, Boping and Smith, David K and Holmes, Edward C and Zhu, Huachen and Guan, Yi
Science, ISSN 0036-8075, 01/2016, Volume 351, Issue 6268, pp. 81 - 84
Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir.... 
DROMEDARY CAMELS | ANTIBODIES | TRACT | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | LIVESTOCK | RESPIRATORY SYNDROME CORONAVIRUS | MIDDLE-EAST | Middle East Respiratory Syndrome Coronavirus - classification | Disease Reservoirs - virology | Humans | Molecular Sequence Data | Coinfection - epidemiology | Phylogeny | Coinfection - virology | Camelus - virology | Disease Reservoirs - veterinary | Animals | Coronavirus Infections - veterinary | Coronavirus Infections - epidemiology | Coronavirus Infections - virology | Epidemiological Monitoring | Middle East Respiratory Syndrome Coronavirus - genetics | Recombination, Genetic | Coinfection - veterinary | Saudi Arabia - epidemiology | Middle East Respiratory Syndrome Coronavirus - physiology | Genetic aspects | Coronaviruses | Host-virus relationships | Genetic recombination | Observations | Health aspects | Viruses | Respiratory diseases | Camels | Arabia | Disorders | Outbreaks | Reservoirs | Vaccines | Recombinant
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8. Full Text Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
by Jean Kaoru Millet and Gary R. Whittaker
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 42, pp. 15214 - 15219
Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified betacoronavirus causing high morbidity and mortality in humans. The coronavirus... 
Receptors | Coronavirus | Epithelial cells | Virions | Cell lines | Viruses | Cultured cells | Infections | SARS virus | Vero cells | Furin | Middle East respiratory syndrome coronavirus | Proteolytic activation | Spike protein | Virus entry | proteolytic activation | MECHANISM | MULTIDISCIPLINARY SCIENCES | spike protein | SUSCEPTIBILITY | TMPRSS2 | CLEAVAGE | MEMBRANE-FUSION | DISEASES | virus entry | INFLUENZA-VIRUS | furin | INFECTIOUS-BRONCHITIS VIRUS | 2 DISTINCT SITES | Genetic Predisposition to Disease | Spike Glycoprotein, Coronavirus - metabolism | Receptors, Virus - metabolism | Humans | Computational Biology | Gene Silencing | Cercopithecus aethiops | Furin - chemistry | Virus Internalization | Animals | Time Factors | HEK293 Cells | Cell Line, Tumor | Mutation | Vero Cells | Middle East Respiratory Syndrome Coronavirus - physiology | Peptide Hydrolases - metabolism | RNA, Small Interfering - metabolism | Host-parasite relationships | Research | Viral proteins | Virus research | Health aspects | Biological Sciences
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9. Full Text Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
by Wilde, Aiaan and Jochmans, Dirk and Posthuma, Clara and Zevenhoven-Dobbe, Jessika and Nieuwkoop, Stefan and Bestebroer, Theo and Hoogen, Bernadette and Neyts, J and Snijder, Eric
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2014, Volume 58, Issue 8, pp. 4875 - 4884
textabstractCoronaviruses can cause respiratory and enteric disease in a wide variety of human and animal hosts. The 2003 outbreak of severe acute respiratory... 
PHARMACOLOGICAL-TREATMENT | IN-VITRO | MERS-CORONAVIRUS | ENDOCYTIC PATHWAY | PAPAIN-LIKE | SARS CORONAVIRUS | HUMAN BETACORONAVIRUS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | FUNCTIONAL RECEPTOR | SAUDI-ARABIA | RHESUS MACAQUES | Cell Line | Coronavirus 229E, Human - drug effects | Small Molecule Libraries - pharmacology | Virus Replication - drug effects | Antiviral Agents - pharmacology | Lopinavir - pharmacology | Humans | Coronavirus 229E, Human - physiology | Cercopithecus aethiops | Loperamide - pharmacology | Middle East Respiratory Syndrome Coronavirus - drug effects | SARS Virus - drug effects | Chlorpromazine - pharmacology | Hepatocytes - pathology | Drug Approval | Chloroquine - pharmacology | Animals | High-Throughput Screening Assays | Hepatocytes - virology | Inhibitory Concentration 50 | SARS Virus - physiology | Vero Cells | Hepatocytes - drug effects | Middle East Respiratory Syndrome Coronavirus - physiology | Antiviral Agents
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