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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 10/2007, Volume 293, Issue 4, pp. 2009 - 2023
Hypertension commonly occurs in conjunction with insulin resistance and other components of the cardiometabolic syndrome. Insulin resistance plays a... 
C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | SPONTANEOUSLY HYPERTENSIVE-RATS | NITRIC-OXIDE SYNTHASE | FATTY-ACID-METABOLISM | NECROSIS-FACTOR-ALPHA | VASCULAR SMOOTH-MUSCLE | MYOCARDIAL BLOOD-FLOW | GROWTH-FACTOR I | ACUTE ENDOTHELIAL DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | Kidney Diseases - physiopathology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Metabolic Syndrome - metabolism | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Renin-Angiotensin System | Myocardium - metabolism | Metabolic Syndrome - physiopathology | Kidney Diseases - complications | Diabetes Mellitus, Type 2 - complications | Kidney Diseases - metabolism | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Angiotensin II - metabolism | Cardiovascular Diseases - metabolism | Mineralocorticoids - metabolism | Signal Transduction | Risk Factors | Endothelium, Vascular - physiopathology | Insulin Resistance | Hypertension - physiopathology | Metabolic Syndrome - complications | Hypertension - metabolism | Insulin - metabolism | Animals | Diabetes Mellitus, Type 2 - physiopathology | Endothelium, Vascular - metabolism | Muscle, Skeletal - physiopathology | Receptor, Angiotensin, Type 1 - metabolism | Hypertension - complications | Chronic Disease | Insulin-Like Growth Factor I - metabolism
Journal Article
Journal of the American Heart Association, ISSN 2047-9980, 10/2016, Volume 5, Issue 10, p. n/a
Background Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1)... 
caveolin 1 | mineralocorticoid receptor | dyslipidemia | insulin resistance | aldosterone | eplerenone | Insulin resistance | Caveolin 1 | Eplerenone | Aldosterone | Mineralocorticoid receptor | Dyslipidemia | METABOLIC SYNDROME | OXIDATIVE STRESS | CAVEOLIN-1-DEFICIENT MICE | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | VASCULAR RELAXATION | MINERALOCORTICOID RECEPTOR BLOCKADE | DIETARY-SODIUM | INSULIN-RESISTANCE | ADIPOCYTE DYSFUNCTION | ALDOSE REDUCTASE | Dyslipidemias - genetics | Aldehyde Reductase - genetics | Hypertriglyceridemia - genetics | Resistin - genetics | Receptors, Mineralocorticoid - metabolism | Humans | Middle Aged | Lipoproteins, HDL - metabolism | Homeostasis | Male | RNA, Messenger - metabolism | Young Adult | Adipose Tissue - metabolism | Aldosterone - metabolism | Spironolactone - pharmacology | Mineralocorticoid Receptor Antagonists - pharmacology | Adult | Aldehyde Reductase - metabolism | Female | Lipid Metabolism - genetics | Retinol-Binding Proteins, Plasma - metabolism | Spironolactone - analogs & derivatives | Resistin - metabolism | NADPH Oxidase 4 - genetics | Signal Transduction | Gene Frequency | Liver - metabolism | Caveolin 1 - genetics | Hypertriglyceridemia - metabolism | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Triglycerides - metabolism | Blood Glucose - drug effects | Insulin - metabolism | NADPH Oxidase 4 - metabolism | Animals | Adolescent | Insulin Resistance - genetics | Dyslipidemias - metabolism | Glucose - metabolism | Aged | Mice | Polymorphism, Single Nucleotide | Retinol-Binding Proteins, Plasma - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49036
We have previously shown that the eye is a mineralocorticoid-sensitive organ and we now question the role of mineralocorticoid receptor (MR) in ocular... 
CELLS | TUMOR-NECROSIS-FACTOR | NITRIC-OXIDE SYNTHASE | RAT OCULAR-TISSUES | INFLAMMATION | SPIRONOLACTONE | MULTIDISCIPLINARY SCIENCES | DIABETIC-NEPHROPATHY | INHIBITOR | EXPRESSION | CILIARY BODY | Microglia - metabolism | Receptors, Mineralocorticoid - genetics | Ciliary Body - pathology | Intravitreal Injections | Spironolactone - administration & dosage | Receptors, Mineralocorticoid - metabolism | Humans | Endotoxins | Rats, Inbred Lew | Receptors, Glucocorticoid - metabolism | Anti-Inflammatory Agents - metabolism | Aldosterone - administration & dosage | Lipopolysaccharides | Aqueous Humor - metabolism | Spironolactone - pharmacology | Inflammation Mediators - metabolism | Iris - drug effects | Iris - enzymology | Anti-Inflammatory Agents - therapeutic use | Microglia - pathology | Female | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - genetics | Uveitis - metabolism | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Ciliary Body - enzymology | Uveitis - drug therapy | Rats | Aldosterone - pharmacology | Down-Regulation - drug effects | Iris - pathology | Down-Regulation - genetics | Animals | Signal Transduction - drug effects | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - metabolism | Receptors, Glucocorticoid - genetics | Chemokines - metabolism | Aqueous Humor - drug effects | Uveitis - chemically induced | Uveitis - pathology | Enzymes | Anti-inflammatory drugs | Corticosterone | Analysis | Uveitis | Inflammation | Aldosterone | Mitogens | Steroids | Glucocorticoids | Mortality | Adipocytes | Injection | Tumor necrosis factor-α | Macrophages | Gene expression | Microglia | Cell adhesion & migration | Eye | Iris | Rodents | Nitric oxide | γ-Interferon | Down-regulation | Structural damage | Tumor necrosis factor-TNF | Interferon | Diabetes
Journal Article
Journal Article
Psychoneuroendocrinology, ISSN 0306-4530, 2015, Volume 62, pp. 204 - 216
Highlights • Stress responses are greater in prenatally stressed F2 generation female offspring. • Stress responses are attenuated in prenatally stressed F2... 
Endocrinology & Metabolism | Psychiatry | Sex differences | Anxiety | HPA axis | Glucocorticoids | Trans-generational | Prenatal stress | PSYCHOLOGICAL STRESS | PSYCHIATRY | BRAIN-DEVELOPMENT | HORMONE-RECEPTOR 1 | NEUROSCIENCES | MATERNAL STRESS | MESSENGER-RNAS | CORTICOTROPIN-RELEASING-FACTOR | FEMALE RATS | ANXIETY-RELATED BEHAVIOR | ENDOCRINOLOGY & METABOLISM | PITUITARY-ADRENAL AXIS | ESTROUS-CYCLE | Receptors, Mineralocorticoid - genetics | Depression - physiopathology | Receptors, Mineralocorticoid - metabolism | Male | Receptors, Glucocorticoid - metabolism | Depression - metabolism | Stress, Psychological - metabolism | Female | Corticotropin-Releasing Hormone - genetics | Corticosterone - blood | Anxiety - metabolism | Hypothalamo-Hypophyseal System - physiopathology | Adrenocorticotropic Hormone - blood | Pituitary-Adrenal System - physiopathology | Pituitary-Adrenal System - metabolism | Anxiety - physiopathology | Rats | Behavior, Animal - physiology | Prenatal Exposure Delayed Effects - physiopathology | Rats, Sprague-Dawley | Corticotropin-Releasing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Prenatal Exposure Delayed Effects - metabolism | Pregnancy | Hippocampus - metabolism | Animals | Paraventricular Hypothalamic Nucleus - metabolism | Receptors, Glucocorticoid - genetics | Sex Factors | Stress, Psychological - physiopathology | Gene expression | Corticosteroids
Journal Article
Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 5/2016, Volume 468, Issue 5, pp. 895 - 908
Journal Article
Comparative Biochemistry and Physiology, Part A, ISSN 1095-6433, 11/2015, Volume 189, pp. 45 - 57
Interacting effects of feeding and stress on corticoid responses in fish were investigated in common carp fed 3.0% or 0.5% body mass (BM) which received no... 
Energy metabolism | Hydromineral balance | Corticoid receptors | Stress | Rhesus glycoprotein | Cyprinid | CORTICOSTEROID RECEPTORS | PHYSIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASMA-CORTISOL | WATER RAINBOW-TROUT | MESSENGER-RNA LEVELS | FRESH-WATER | MINERALOCORTICOID RECEPTOR | GLUCOCORTICOID-RECEPTOR | ZOOLOGY | HIGH ENVIRONMENTAL AMMONIA | SEAWATER ACCLIMATION | TROUT ONCORHYNCHUS-MYKISS | Lactates - blood | Receptors, Mineralocorticoid - genetics | Sodium-Potassium-Exchanging ATPase - genetics | Gene Expression - drug effects | Receptors, Mineralocorticoid - metabolism | Water-Electrolyte Balance - drug effects | Protein Transport - drug effects | Receptors, Glucocorticoid - metabolism | Fish Proteins - genetics | Gills - drug effects | Kidney - metabolism | Glycogen - metabolism | Liver - drug effects | Cation Transport Proteins - metabolism | Cation Transport Proteins - genetics | Energy Metabolism - physiology | Hydrocortisone - blood | Muscles - metabolism | Carps - physiology | Water-Electrolyte Balance - physiology | Kidney - drug effects | Liver - metabolism | Fish Proteins - metabolism | Gills - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Feeding Behavior - physiology | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Muscles - drug effects | Receptors, Glucocorticoid - genetics | Hydrocortisone - pharmacology | Blood Glucose - metabolism | Energy Metabolism - drug effects | Carp | Corticosteroids | Glycogen | Liver | Glucose | Dextrose | Adenosine triphosphatase | Steroids | Index Medicus
Journal Article
Hypertension, ISSN 0194-911X, 09/2011, Volume 58, Issue 3, pp. 479 - 488
Adipose tissue influences vascular function through adipocyte-derived factors, including components of the renin-angiotensin-aldosterone system. Molecular... 
Adipocyte-secreted factors | corticosteroid receptors | inflammation | vascular smooth muscle cells | KINASE | PHENOTYPE | ANGIOTENSIN-II | adipocyte-secreted factors | OBESITY | PERIPHERAL VASCULAR DISEASE | ALDOSTERONE | HYPERTENSION | PERIVASCULAR ADIPOSE-TISSUE | EXPRESSION | Fadrozole - pharmacology | Receptors, Glucocorticoid - antagonists & inhibitors | Muscle, Smooth, Vascular - metabolism | Receptors, Mineralocorticoid - metabolism | Culture Media, Conditioned - chemistry | Adipocytes - cytology | Culture Media, Conditioned - pharmacology | Receptors, Glucocorticoid - metabolism | Adipocytes - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Aldosterone - metabolism | Spironolactone - pharmacology | Phosphorylation - drug effects | Spironolactone - analogs & derivatives | Myocytes, Smooth Muscle - drug effects | Mineralocorticoid Receptor Antagonists | Myocytes, Smooth Muscle - metabolism | Angiotensin II - metabolism | Mice, Inbred C57BL | Cells, Cultured | 3T3-L1 Cells | Muscle, Smooth, Vascular - cytology | Blotting, Western | Fibronectins - metabolism | Hormone Antagonists - pharmacology | Animals | Adipocytes - metabolism | Receptor, Angiotensin, Type 1 - metabolism | Corticosterone - metabolism | Mice | Mifepristone - pharmacology | Proliferating Cell Nuclear Antigen - metabolism | Culture Media, Conditioned - metabolism | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 06/2016, Volume 301, pp. 31 - 41
Hypertension is accompanied by perturbations to the endocannabinoid and antioxidant systems. Thus, potential pharmacological treatments for hypertension should... 
Hypertension | URB597 | Oxidative stress | Endocannabinoid system | Liver | LIPID-PEROXIDATION | NADPH OXIDASE ACTIVITY | BLOOD-PRESSURE | CELL-DEATH | ACID AMIDE HYDROLASE | INDUCED OXIDATIVE STRESS | CARDIOVASCULAR FUNCTION | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | NF-KAPPA-B | SUPEROXIDE-DISMUTASE | Amidohydrolases - metabolism | Endocannabinoids - metabolism | Glutathione Peroxidase - metabolism | Reactive Oxygen Species - metabolism | Rats, Wistar | Glutathione - metabolism | Glutathione Transferase - metabolism | Amidohydrolases - antagonists & inhibitors | Desoxycorticosterone Acetate | Male | Phospholipases A2 - metabolism | Glutathione Disulfide - metabolism | Hypertension - metabolism | Catalase - metabolism | Monoacylglycerol Lipases - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Liver - drug effects | Hypertension - chemically induced | Benzamides - pharmacology | Superoxide Dismutase - metabolism | Carbamates - pharmacology | Antioxidants | Lipase | Fatty acids | Index Medicus | OXIDATION | TRANSCRIPTION FACTORS | HOMEOSTASIS | LIPASES | ANTIOXIDANTS | GLYCEROL | RATS | 60 APPLIED LIFE SCIENCES | METABOLISM | GLUTATHIONE | ACTIVITY LEVELS | INFLAMMATION | LIVER | CHRONIC INTAKE | DOPAMINE | CARBOXYLIC ACIDS | MINERALOCORTICOIDS | HYPERTENSION | RECEPTORS | AMIDES | LIPIDS | PEROXIDASES | VITAMIN E
Journal Article
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 4105 - 4114
Journal Article
Cell Metabolism, ISSN 1550-4131, 11/2013, Volume 18, Issue 5, pp. 660 - 671
Journal Article