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Cell, ISSN 0092-8674, 2009, Volume 139, Issue 4, pp. 719 - 730
The licensing of eukaryotic DNA replication origins, which ensures once-per-cell-cycle replication, involves the loading of six related minichromosome... 
DNA | MINICHROMOSOME MAINTENANCE PROTEIN | RECOGNITION COMPLEX INTERACTS | IN-VITRO | BUDDING YEAST | HELICASE ACTIVITY | STRUCTURAL-CHANGES | DORMANT ORIGINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SACCHAROMYCES-CEREVISIAE | ATP-HYDROLYSIS | T-ANTIGEN | CELL BIOLOGY | Chromosomal Proteins, Non-Histone - isolation & purification | Nuclear Proteins - isolation & purification | Minichromosome Maintenance Complex Component 6 | Minichromosome Maintenance Complex Component 7 | Origin Recognition Complex - metabolism | Minichromosome Maintenance Complex Component 3 | Minichromosome Maintenance Complex Component 4 | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Saccharomyces cerevisiae Proteins - isolation & purification | Cell Cycle Proteins - isolation & purification | Chromosomal Proteins, Non-Histone - metabolism | Cell Cycle Proteins - metabolism | Models, Molecular | DNA Replication | Nuclear Proteins - metabolism | DNA - metabolism | DNA-Binding Proteins - isolation & purification | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | DNA Helicases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Chromosomal Proteins, Non-Histone - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Proteins | DNA replication | Research | Oncology, Experimental | Cancer | Index Medicus
Journal Article
Journal of biochemistry, ISSN 0021-924X, 12/2018, Volume 164, Issue 6, pp. 449 - 460
The amino-terminal region of eukaryotic MCM4 is characteristic of the presence of a number of phosphorylation sites for CDK and DDK, suggesting that the region... 
replication | COMPLEX | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | DNA-REPLICATION | INHIBITION | ROLES | DNA | CELL-CYCLE | helicase | protein kinases/CDKs | phosphorylation | BINDING | Minichromosome Maintenance Complex Component 4 - genetics | Phosphorylation | Humans | Minichromosome Maintenance Complex Component 7 - chemistry | Protein Multimerization | Recombinant Fusion Proteins - metabolism | Gene Deletion | S Phase | Minichromosome Maintenance Complex Component 6 - chemistry | Minichromosome Maintenance Complex Component 4 - chemistry | Oligopeptides - chemistry | Peptide Fragments - genetics | Cyclin-Dependent Kinase 2 - metabolism | Peptide Fragments - metabolism | Mutagenesis, Site-Directed | Minichromosome Maintenance Complex Component 6 - genetics | Cyclin A - metabolism | Oligopeptides - genetics | Enzyme Stability | Oligopeptides - metabolism | Recombinant Fusion Proteins - chemistry | Arginine - chemistry | Minichromosome Maintenance Complex Component 6 - metabolism | Point Mutation | Minichromosome Maintenance Complex Component 4 - metabolism | Peptide Fragments - chemistry | Minichromosome Maintenance Complex Component 7 - metabolism | Minichromosome Maintenance Complex Component 7 - genetics | Protein Processing, Post-Translational | HeLa Cells | Amino Acid Substitution | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 6/2006, Volume 173, Issue 5, pp. 673 - 683
In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2-7 (Mcm2-7).... 
Replication origin | Molecules | Chromatin | Spermatozoa | DNA replication | Gels | Interphase | DNA | Small interfering RNA | Ova | CYCLIN-DEPENDENT KINASES | REPLICON INITIATION | RECOGNITION COMPLEX | XENOPUS EGG EXTRACTS | PREREPLICATION COMPLEX | EUKARYOTIC DNA-REPLICATION | MINICHROMOSOME MAINTENANCE PROTEINS | ULTRAVIOLET-LIGHT | SACCHAROMYCES-CEREVISIAE | S-PHASE CHECKPOINT | CELL BIOLOGY | Cell Cycle Proteins - drug effects | Chromatin - metabolism | Hydroxyurea - pharmacology | DNA Replication - drug effects | Oxidative Stress - physiology | Adenosine Triphosphatases - drug effects | Minichromosome Maintenance Complex Component 7 | Carrier Proteins - drug effects | Minichromosome Maintenance Complex Component 2 | Minichromosome Maintenance Complex Component 3 | Minichromosome Maintenance Complex Component 4 | DNA-Binding Proteins - metabolism | Aphidicolin - pharmacology | Time Factors | Caffeine - pharmacology | Nuclear Proteins - drug effects | Chromatin - drug effects | Cell Survival - drug effects | Xenopus Proteins - drug effects | Caenorhabditis elegans - growth & development | Xenopus laevis | Cell Cycle Proteins - metabolism | DNA-Binding Proteins - drug effects | Adenosine Triphosphatases - metabolism | Nuclear Proteins - metabolism | Animals | Caenorhabditis elegans - drug effects | Carrier Proteins - metabolism | DNA Replication - physiology | Replication Origin | Xenopus Proteins - metabolism | Dormancy (Biology) | Research | Index Medicus
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 11/2000, Volume 20, Issue 22, pp. 8602 - 8612
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 04/2006, Volume 98, Issue 7, pp. 472 - 482
Background. Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective collections of frozen tumors.... 
GEMININ | INHIBITION | ONCOLOGY | METASTASES | CLASSIFICATION | MALIGNANT-MELANOMA | MICROARRAYS | CANCER | PROGRESSION | DNA-REPLICATION | REVEALS | Immunohistochemistry | Multivariate Analysis | Predictive Value of Tests | Up-Regulation | Cell Cycle Proteins - analysis | Nuclear Proteins - analysis | Prognosis | Follow-Up Studies | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Skin Neoplasms - chemistry | Child, Preschool | DNA-Binding Proteins - analysis | Infant | Male | Minichromosome Maintenance Complex Component 6 | Gene Expression Profiling | Minichromosome Maintenance Complex Component 3 | Minichromosome Maintenance Complex Component 4 | Melanoma - genetics | Skin Neoplasms - mortality | Cell Division | Aged, 80 and over | Cell Cycle Proteins - genetics | Adult | Female | Geminin | alpha Karyopherins - analysis | Child | Melanoma - chemistry | Skin Neoplasms - pathology | Biomarkers, Tumor - analysis | Proportional Hazards Models | Melanoma - pathology | Reverse Transcriptase Polymerase Chain Reaction | Disease-Free Survival | RNA, Complementary - analysis | Skin Neoplasms - genetics | Adolescent | Survival Analysis | Aged | Biomarkers, Tumor - genetics | Cohort Studies | Melanoma - mortality | Genetic aspects | Research | Gene expression | Melanoma | Cancer | Oncology | Clinical outcomes | Tumors | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 05/2014, Volume 111, Issue 18, pp. E1899 - E1908
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2017, Volume 45, Issue 1, pp. 169 - 180
DNA replication is tightly regulated to occur once and only once per cell cycle. How chromatin, the physiological substrate of DNA replicationmachinery,... 
RECRUITMENT | HBO1 HISTONE ACETYLASE | DAMAGE SITES | METHYLATION | INSTABILITY | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMBRYONIC STEM | PERICENTRIC HETEROCHROMATIN | GENOME | Minichromosome Maintenance Complex Component 4 - genetics | Cell Cycle - genetics | Chromatin - metabolism | NIH 3T3 Cells | RNA, Small Interfering - genetics | DNA Polymerase III - genetics | Lamin Type B - genetics | Humans | Cell Nucleus - metabolism | Proliferating Cell Nuclear Antigen - genetics | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Osteoblasts - cytology | Chromatin - chemistry | HCT116 Cells | Cell Cycle Proteins - metabolism | DNA Replication | Jumonji Domain-Containing Histone Demethylases - genetics | Proto-Oncogene Proteins c-myc - metabolism | Lamin Type B - metabolism | Minichromosome Maintenance Complex Component 4 - metabolism | Animals | Histones - genetics | Cell Nucleus - genetics | Cell Line, Tumor | Mice | Proto-Oncogene Proteins c-myc - genetics | HeLa Cells | Histones - metabolism | DNA Polymerase III - metabolism | Methylation | Osteoblasts - metabolism | Proliferating Cell Nuclear Antigen - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Gene regulation, Chromatin and Epigenetics
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 6/2004, Volume 165, Issue 6, pp. 789 - 800
Journal Article