X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (20965) 20965
Newspaper Article (340) 340
Book Chapter (242) 242
Magazine Article (30) 30
Book / eBook (18) 18
Dissertation (8) 8
Trade Publication Article (4) 4
Newsletter (3) 3
Conference Proceeding (1) 1
Publication (1) 1
Reference (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (15426) 15426
animals (14783) 14783
life sciences & biomedicine (13574) 13574
mitochondria (11741) 11741
rats (6622) 6622
humans (6522) 6522
male (6239) 6239
mitochondria - metabolism (6103) 6103
mitochondria - drug effects (4356) 4356
apoptosis (4190) 4190
cell biology (4085) 4085
biochemistry & molecular biology (3669) 3669
oxidative stress (3559) 3559
mice (3443) 3443
mitochondria, heart - drug effects (3124) 3124
mitochondria, heart - metabolism (3032) 3032
proteins (2783) 2783
mitochondrial dna (2696) 2696
reactive oxygen species - metabolism (2524) 2524
metabolism (2309) 2309
female (2308) 2308
physiology (2186) 2186
rodents (2061) 2061
physiological aspects (1904) 1904
apoptosis - drug effects (1901) 1901
reactive oxygen species (1899) 1899
rats, wistar (1890) 1890
research article (1856) 1856
science & technology - other topics (1839) 1839
myocardium - metabolism (1819) 1819
calcium - metabolism (1794) 1794
medicine (1793) 1793
rats, sprague-dawley (1786) 1786
multidisciplinary sciences (1745) 1745
research (1723) 1723
pharmacology & pharmacy (1717) 1717
heart (1690) 1690
cells, cultured (1687) 1687
oxidative stress - drug effects (1560) 1560
cardiovascular system & cardiology (1519) 1519
analysis (1513) 1513
neurosciences (1506) 1506
signal transduction (1506) 1506
antioxidants (1480) 1480
gene expression (1477) 1477
in vitro techniques (1468) 1468
phosphorylation (1466) 1466
kinases (1437) 1437
ischemia (1425) 1425
heart - drug effects (1388) 1388
neurosciences & neurology (1352) 1352
cardiac & cardiovascular systems (1347) 1347
enzymes (1347) 1347
biology (1345) 1345
science (1329) 1329
oxygen consumption - drug effects (1291) 1291
oxidation-reduction (1275) 1275
biochemistry (1261) 1261
adenosine triphosphate - metabolism (1224) 1224
cell death (1224) 1224
health aspects (1194) 1194
disease models, animal (1193) 1193
cancer (1161) 1161
cell line (1148) 1148
mice, inbred c57bl (1113) 1113
kinetics (1103) 1103
cattle (1092) 1092
life sciences (1078) 1078
calcium (1071) 1071
dose-response relationship, drug (1070) 1070
membrane potential, mitochondrial - drug effects (1069) 1069
diabetes (1054) 1054
oncology (1034) 1034
myocytes, cardiac - metabolism (1028) 1028
myocytes, cardiac - drug effects (1022) 1022
energy metabolism (1005) 1005
time factors (1003) 1003
permeability (991) 991
inflammation (987) 987
homeostasis (984) 984
oxidative phosphorylation (983) 983
chemistry (980) 980
mitochondria, liver - drug effects (976) 976
medicine, research & experimental (971) 971
research & experimental medicine (971) 971
mitochondria, liver - metabolism (969) 969
biochemistry, general (962) 962
mitochondria - physiology (959) 959
endocrinology & metabolism (948) 948
aging (944) 944
review (940) 940
biophysics (938) 938
mitochondria - enzymology (911) 911
electron transport (903) 903
studies (895) 895
mitochondria - pathology (890) 890
mitochondria, heart - enzymology (880) 880
membrane potential (861) 861
cardiomyocytes (855) 855
liver (843) 843
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (5) 5
Earth Sciences (Noranda) - Circulation Desk (2) 2
Earth Sciences (Noranda) - Oversize (2) 2
Earth Sciences (Noranda) - Stacks (2) 2
Gerstein Science - Circulation Desk (2) 2
Gerstein Science - Reserve desk (2) 2
St. Michael's College (John M. Kelly) - 2nd Floor (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (2) 2
Trinity College (John W Graham) - Stacks (2) 2
UofT at Mississauga - Circulation Desk (2) 2
Victoria University E.J. Pratt - Circulation Desk (2) 2
Victoria University E.J. Pratt - Oversize (2) 2
Online Resources - Online (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (21224) 21224
Russian (211) 211
Japanese (148) 148
Chinese (90) 90
German (56) 56
Ukrainian (42) 42
Italian (33) 33
French (30) 30
Slovak (28) 28
Portuguese (20) 20
Spanish (15) 15
Polish (10) 10
Norwegian (7) 7
Czech (6) 6
Dutch (6) 6
Korean (3) 3
Bulgarian (2) 2
Hungarian (2) 2
Croatian (1) 1
Persian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature medicine, ISSN 1546-170X, 11/2016, Volume 22, Issue 12, pp. 1428 - 1438
Journal Article
Nature medicine, ISSN 1546-170X, 04/2016, Volume 22, Issue 5, pp. 547 - 556
Doxorubicin is an anthracycline chemotherapy agent effective in treating a wide range of malignancies, but it causes a dose-related cardiotoxicity that can lead to heart failure in a subset of patients... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Mitochondria, Heart - metabolism | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Calcium - metabolism | Humans | Middle Aged | Transcriptome | Antibiotics, Antineoplastic - adverse effects | Mitochondria, Heart - drug effects | Membrane Potential, Mitochondrial - drug effects | Flow Cytometry | Adult | Female | Real-Time Polymerase Chain Reaction | Cardiotoxicity - genetics | DNA Damage - drug effects | Cell Survival - drug effects | Disease Susceptibility | Heart Failure - genetics | Breast Neoplasms - drug therapy | Myocytes, Cardiac - drug effects | Fluorescent Antibody Technique | Myocytes, Cardiac - metabolism | Aged | Polymorphism, Single Nucleotide | Oxidative Stress - drug effects | Induced Pluripotent Stem Cells | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Heart Failure - chemically induced | Complications and side effects | Patient outcomes | Stem cells | Development and progression | Breast cancer | Transplantation | Cardiovascular diseases | Drug therapy | Doxorubicin | Methods | Heart failure | Chemotherapy | Toxicity | Index Medicus
Journal Article
Nature medicine, ISSN 1546-170X, 07/2006, Volume 12, Issue 8, pp. 908 - 916
.... Here we report ten individuals who developed severe congestive heart failure while on imatinib and we show that imatinib-treated mice develop left ventricular contractile dysfunction... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Mitochondria, Heart - ultrastructure | Piperazines - administration & dosage | Calcium - metabolism | Mitochondria, Heart - pathology | Sarcoplasmic Reticulum - drug effects | Humans | Piperazines - toxicity | Antineoplastic Agents - administration & dosage | Mitochondria, Heart - drug effects | Ventricular Dysfunction, Left - chemically induced | Antineoplastic Agents - toxicity | Dose-Response Relationship, Drug | Mitochondrial Membranes - drug effects | Pyrimidines - toxicity | Time Factors | Adenosine Triphosphatases - analysis | Antineoplastic Agents - adverse effects | Sarcoplasmic Reticulum - ultrastructure | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Membrane Potentials - drug effects | Severity of Illness Index | Cytochromes c - secretion | Echocardiography | Pyrimidines - administration & dosage | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Adenosine Triphosphatases - metabolism | Heart Failure - pathology | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - adverse effects | Piperazines - pharmacology | Ventricular Dysfunction, Left - physiopathology | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Cell Membrane Permeability - drug effects | Pyrimidines - adverse effects | Sarcoplasmic Reticulum - pathology | Mice | Benzamides | Myocytes, Cardiac - ultrastructure | Heart Failure - chemically induced | Heart failure | Chemotherapy | Side effects | Inhibitor drugs | Toxicity | Cardiovascular disease | Cancer | Index Medicus
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 11/2013, Volume 305, Issue 10, pp. H1440 - H1450
Xanthine oxidase (XO) is increased in human and rat left ventricular (LV) myocytes with volume overload (VO) of mitral regurgitation and aortocaval fistula... 
Heart failure | Xanthine oxidase | Mitochondria | Volume overload | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Sarcoplasmic Reticulum - drug effects | Heart Failure - enzymology | Heart Failure - physiopathology | Systole - drug effects | Heart Ventricles - diagnostic imaging | Sarcoplasmic Reticulum - enzymology | Myocytes, Cardiac - enzymology | Time Factors | Adenosine Triphosphate - metabolism | Heart Ventricles - enzymology | Ultrasonography | Diastole - drug effects | Heart Failure - etiology | Xanthine Oxidase - antagonists & inhibitors | Disease Models, Animal | Xanthine Oxidase - metabolism | Ventricular Function, Left - drug effects | Enzyme Inhibitors - pharmacology | Ventricular Pressure - drug effects | Rats | Stroke Volume - drug effects | Cardiotonic Agents - pharmacology | Rats, Sprague-Dawley | Heart Failure - drug therapy | Animals | Myocytes, Cardiac - drug effects | Heart Ventricles - physiopathology | Calcium Signaling - drug effects | Oxygen Consumption - drug effects | Creatine Kinase - metabolism | Allopurinol - pharmacology | Hemodynamics - drug effects | Energy Metabolism - drug effects | Heart Ventricles - drug effects | Oxidases | Physiological aspects | Xanthine | Health aspects | Heart ventricle, Left | Index Medicus | Call for Papers | volume overload | heart failure | xanthine oxidase | mitochondria
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2009, Volume 296, Issue 5, pp. 1466 - 1483
Doxorubicin (DOX) is a potent available antitumor agent; however, its clinical use is limited because of its cardiotoxicity. Cell death is a key component in... 
Heart failure | Hemodynamics | Inducible nitric oxide synthase | Apoptosis | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Free Radical Scavengers - pharmacology | Antibiotics, Antineoplastic - toxicity | Mitochondria, Heart - metabolism | Heart Diseases - metabolism | Apoptosis - drug effects | Mitochondria, Heart - pathology | Antioxidants - metabolism | Myocardial Contraction - drug effects | Heart Diseases - prevention & control | Male | Mitochondria, Heart - drug effects | Tyrosine - analogs & derivatives | Necrosis | Dose-Response Relationship, Drug | Matrix Metalloproteinase 9 - metabolism | Nitric Oxide Synthase Type II - antagonists & inhibitors | Superoxides - metabolism | Nitric Oxide Donors - pharmacology | Heart Diseases - chemically induced | Cell Line | Heart Diseases - physiopathology | Matrix Metalloproteinase 2 - metabolism | Mice, Inbred C57BL | Nitric Oxide Synthase Type II - deficiency | Ventricular Function, Left - drug effects | Enzyme Inhibitors - pharmacology | Ventricular Pressure - drug effects | Doxorubicin - toxicity | Mice, Knockout | Myocytes, Cardiac - pathology | Poly(ADP-ribose) Polymerases - metabolism | Tyrosine - metabolism | Animals | Myocytes, Cardiac - drug effects | Nitric Oxide Synthase Type II - genetics | Peroxynitrous Acid - metabolism | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide - metabolism | Heart Diseases - pathology | Index Medicus | heart failure | apoptosis | hemodynamics | inducible nitric oxide synthase
Journal Article
Circulation. Heart failure, ISSN 1941-3289, 12/2017, Volume 10, Issue 12
Journal Article
Journal of the American Heart Association, ISSN 2047-9980, 07/2016, Volume 5, Issue 7, p. n/a
Journal Article