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Circulation research, ISSN 1524-4571, 04/2016, Volume 118, Issue 7, pp. 1151 - 1169
Heart failure is associated with generalized insulin resistance. Moreover, insulin-resistant states such as type 2 diabetes mellitus and obesity increases the risk of heart failure even after adjusting for traditional risk factors... 
heart failure | diabetes mellitus | myocardium | insulin receptor | insulin resistance | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Glucose Transporter Type 4 - metabolism | Insulin - physiology | Humans | Heart Failure - physiopathology | Heart Failure - prevention & control | Heart Failure - therapy | Insulin Resistance - physiology | Myocardial Ischemia - physiopathology | Fatty Acids - metabolism | Heart Failure - etiology | Myocytes, Smooth Muscle - metabolism | Diabetes Mellitus, Type 2 - complications | Disease Models, Animal | Hyperinsulinism - physiopathology | Endothelial Cells - metabolism | Obesity - complications | Risk Factors | Obesity - physiopathology | Receptor, Insulin - physiology | Ventricular Remodeling - physiology | Forecasting | Disease Progression | Protein Transport | Animals | Diabetes Mellitus, Type 2 - physiopathology | Mitochondria, Heart - physiology | Myocardial Ischemia - complications | Glucose - metabolism | Myocytes, Cardiac - metabolism | Signal Transduction - physiology | Dietary Fats - toxicity | Index Medicus | Metabolic Syndrome | Heart Failure | Remodeling | cardiac hypertrophy | Hypertrophy | Insulin action
Journal Article
Circulation (New York, N.Y.), ISSN 0009-7322, 05/2010, Volume 121, Issue 17, pp. 1912 - 1925
.... However, its pathophysiological role in cardiac remodeling and chronic heart failure (HF) is unknown. We hypothesized that induction of HO-1 in HF alleviates pathological remodeling... 
Heart failure | Carbon monoxide | Cardiac remodeling | Ventricular | Heme oxygenase-1 | Apoptosis | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Heme Oxygenase-1 - metabolism | Humans | Oxidative Stress - physiology | Heart Failure - physiopathology | Male | Carbon Monoxide - metabolism | Heme Oxygenase-1 - genetics | Gene Expression - physiology | Myocardial Infarction - pathology | Myocardium - metabolism | Up-Regulation - physiology | Ventricular Dysfunction, Left - pathology | Myocardial Infarction - physiopathology | Mice, Inbred C57BL | Stroke Volume - physiology | Mice, Transgenic | Myocardium - pathology | Cardiotonic Agents - pharmacology | Heart Failure - pathology | Ventricular Remodeling - physiology | Ventricular Dysfunction, Left - physiopathology | Heart Failure - drug therapy | Neovascularization, Physiologic - physiology | Animals | Myocardial Infarction - drug therapy | Ventricular Dysfunction, Left - drug therapy | Fibrosis | Mice | Apoptosis - physiology | Mitochondria - physiology | Chronic Disease | Organometallic Compounds - pharmacology | Prevention | Antioxidants | Usage | Care and treatment | Hemoproteins | Physiological aspects | Research | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article