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Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 9, p. e105339
Journal Article
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 54, Issue 4, pp. 773 - 794
Numerous investigations have shown that mitochondrial dysfunction is a major mechanism of drug-induced liver injury, which involves the parent drug or a... 
Gastroenterology and Hepatology | Drugs | Obesity | Oxidative stress | Mitochondria | Cell death | Lipids | Hepatotoxicity | Steatosis | TRIGLYCERIDE TRANSFER PROTEIN | DNA-POLYMERASE-GAMMA | PREGNANE X-RECEPTOR | PROLIFERATOR-ACTIVATED RECEPTOR | HEPATIC CYTOCHROME-P450 2E1 | ELEMENT-BINDING PROTEINS | FATTY-ACID OXIDATION | CONSTITUTIVE ANDROSTANE RECEPTOR | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RELATED PARAMETERS | GASTROENTEROLOGY & HEPATOLOGY | Carbohydrate Metabolism - drug effects | Reactive Oxygen Species - metabolism | Mitochondria, Liver - metabolism | Humans | Leptin - metabolism | Oxidative Phosphorylation - drug effects | Adipose Tissue - metabolism | Adiponectin - metabolism | Hepatitis C - complications | Cell Death - drug effects | Fatty Acids - metabolism | Chemical and Drug Induced Liver Injury - etiology | Diabetes Mellitus, Type 2 - complications | Genetic Predisposition to Disease | Fatty Liver - metabolism | Oxidation-Reduction | Obesity - complications | Insulin Resistance | Mitochondrial Membrane Transport Proteins - drug effects | Chemical and Drug Induced Liver Injury - genetics | Mitochondria, Liver - drug effects | Animals | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | Lipid Metabolism - drug effects | Alcoholic Intoxication - complications | Genome, Mitochondrial | Adipose Tissue - drug effects | Energy Metabolism - drug effects | Fatty Liver - etiology | Divalproex | Liver diseases | Thiols | Liver | Cytochrome P-450 | Mitochondrial DNA | Triglycerides | Stavudine | Permeability | Valproic acid | Fatty acids | Cells | Carnitine | Metabolites | Glutathione transferase | Acetaminophen | Physiological aspects | DNA polymerases | Health aspects | Zidovudine | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2018, Volume 154, Issue 5, pp. 1465 - 1479.e13
Cirrhosis results from accumulation of myofibroblasts derived from quiescent hepatic stellate cells (Q-HSCs); it regresses when myofibroblastic HSCs are... 
Metabolic Reprogramming | Liver Diseases | Hippo Pathway | Fibrogenesis | FIBROSIS | TRANSCRIPTIONAL ACTIVITY | PULMONARY-HYPERTENSION | FATTY LIVER-DISEASE | MECHANISMS | CANCER | METABOLISM | GLUCOSE | GROWTH | Fibro-genesis | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Liver - pathology | Cell Proliferation | Mitochondria, Liver - metabolism | Humans | Glutamine - metabolism | Hedgehog Proteins - metabolism | Hepatic Stellate Cells - metabolism | Smoothened Receptor - metabolism | Phosphoproteins - metabolism | Smoothened Receptor - genetics | Case-Control Studies | Cellular Reprogramming | Myofibroblasts - metabolism | Transfection | Hedgehog Proteins - genetics | RNA Interference | Time Factors | Liver Cirrhosis - metabolism | Liver Cirrhosis, Experimental - pathology | Cell Transdifferentiation | Ketoglutaric Acids - metabolism | Liver Cirrhosis - genetics | Hepatic Stellate Cells - pathology | Myofibroblasts - pathology | Mitochondria, Liver - pathology | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Rats | Glutaminase - metabolism | Liver Cirrhosis, Experimental - genetics | Phosphoproteins - genetics | Mice, Knockout | Phenotype | Animals | Energy Metabolism | Adaptor Proteins, Signal Transducing - genetics | Liver Cirrhosis - pathology | Adaptor Proteins, Signal Transducing - metabolism | Liver Cirrhosis, Experimental - metabolism | Glucose metabolism | Metabolites | RNA | Analysis | Liver | Physiological aspects | Genetic research | Verteporfin | Development and progression | Mice | Liver cirrhosis | Glutamine
Journal Article
Acta Physiologica, ISSN 1748-1708, 05/2009, Volume 196, Issue 1, pp. 81 - 98
As the liver is central in the maintenance of glucose homeostasis and energy storage, knowledge of the physiology as well as physiopathology of hepatic energy... 
hepatic glucose production | fatty liver | type 2 diabetes | AMP-activated protein kinase | liver | energy metabolism | Type 2 diabetes | Energy metabolism | Fatty liver | Hepatic glucose production | Liver | PHYSIOLOGY | LIPID-METABOLISM | CREB COACTIVATOR TORC2 | ACETYL-COA CARBOXYLASE | MICE LACKING ADIPONECTIN | LIVER-DISEASE | ISOLATED RAT HEPATOCYTES | SKELETAL-MUSCLE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | ADIPOSE-TISSUE | AMP-Activated Protein Kinases - metabolism | Liver - enzymology | Hypoglycemic Agents - metabolism | Humans | Homeostasis | Protein Subunits - metabolism | Liver Cirrhosis - metabolism | Aminoimidazole Carboxamide - metabolism | Energy Metabolism - physiology | Protein Subunits - genetics | Liver Cirrhosis - drug therapy | Dyslipidemias - drug therapy | Ribonucleotides - metabolism | Fatty Liver - metabolism | Fatty Liver - physiopathology | Lipid Metabolism | Mitochondria - metabolism | AMP-Activated Protein Kinases - chemistry | Fatty Liver - drug therapy | Gluconeogenesis - physiology | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Dyslipidemias - metabolism | Glucose - metabolism | Protein Conformation | Liver - cytology | Protein Subunits - chemistry | Liver Cirrhosis - physiopathology | AMP-Activated Protein Kinases - genetics | Dyslipidemias - physiopathology | Glucose metabolism | Enzymes | Liver diseases | Physiological aspects | Protein biosynthesis | Insulin resistance | Glucose | Protein kinases | Health aspects | Fatty acids | Dextrose | cytology | Protein Subunits | Dyslipidemias | AMP-Activated Protein Kinases | therapeutic | Hypoglycemic Agents | Aminoimidazole Carboxamide | Mitochondria | genetics | Gluconeogenesis | chemistry | drug therapy | physiology | Liver Cirrhosis | enzymology | Fatty Liver | physiopathology | Ribonucleotides | Energy Metabolism | analogs & derivatives | MP-activated protein kinase | metabolism
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2015, Volume 125, Issue 12, pp. 4447 - 4462
Journal Article