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Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Index Medicus | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Brain Research, ISSN 0006-8993, 2009, Volume 1311, pp. 189 - 196
Journal Article
Molecular Plant, ISSN 1674-2052, 08/2015, Volume 8, Issue 8, pp. 1237 - 1252
Natural illumination conditions are highly variable and because of their sessile life style, plants are forced to acclimate to them at the cellular and... 
Arabidopsis thaliana | early redox-regulated gene | plastidial redox signaling | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUSTARD SINAPIS-ALBA | PHOTOSYSTEM STOICHIOMETRY ADJUSTMENT | PLANT SCIENCES | MESSENGER-RNA | HIGHER-PLANTS | MITOCHONDRIAL RETROGRADE REGULATION | PHOTOSYNTHETIC ELECTRON-TRANSPORT | CHLOROPLAST DEVELOPMENT | STATE TRANSITIONS | MG-PROTOPORPHYRIN IX | NAC TRANSCRIPTION FACTOR | Transcription, Genetic - drug effects | Arabidopsis - physiology | Electron Transport - drug effects | Reactive Oxygen Species - metabolism | Electron Transport - radiation effects | Genes, Plant | Oxidation-Reduction - radiation effects | Chromatin Assembly and Disassembly - genetics | RNA, Messenger - metabolism | Chromatin Assembly and Disassembly - drug effects | Arabidopsis - radiation effects | Chromatin Assembly and Disassembly - radiation effects | Photosynthesis - genetics | Time Factors | Cell Nucleus - radiation effects | Light | Oxidation-Reduction - drug effects | Plastids - drug effects | Mitochondria - radiation effects | Plastids - metabolism | Signal Transduction - radiation effects | Photosynthesis - radiation effects | Dibromothymoquinone - pharmacology | RNA, Messenger - genetics | Mitochondria - metabolism | Signal Transduction - genetics | Tetrapyrroles - metabolism | Mitochondria - drug effects | Mutation - genetics | Regulatory Sequences, Nucleic Acid - genetics | Arabidopsis - genetics | Gene Expression Regulation, Plant - drug effects | Cell Nucleus - genetics | Signal Transduction - drug effects | Photosynthesis - drug effects | Acclimatization - genetics | Plastids - radiation effects | Acclimatization - drug effects | Cell Nucleus - drug effects | Index Medicus | Life Sciences | Biochemistry, Molecular Biology | Vegetal Biology
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, pp. e50778 - e50778
Background: Hypoxia/reoxygenation(H/R)-induced apoptosis of cardiomyocytes plays an important role in myocardial injury. Lycopene is a potent antioxidant... 
ISCHEMIA-REPERFUSION INJURY | INFARCT SIZE | OXYGEN | INDUCED ACTIVATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | DISEASE | CAROTENOIDS | ANEMIC RATS | AMERICAN-HEART-ASSOCIATION | CELL-DEATH | Animals, Newborn | Cell Survival - drug effects | Cell Hypoxia - drug effects | Mitochondrial Membrane Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - metabolism | Myocytes, Cardiac - cytology | Apoptosis - drug effects | Mice, Inbred C57BL | Protein Conformation - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Carotenoids - pharmacology | Oxygen - metabolism | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Cytoprotection - drug effects | Myocytes, Cardiac - metabolism | Mice | Oxidative Stress - drug effects | Cytochrome c | Infants (Newborn) | Antioxidants | Analysis | Heart cells | Permeability | Lycopene | Apoptosis | Cytochrome | Neonates | Reactive oxygen species | Heart attacks | Mitochondrial permeability transition pore | Membrane permeability | Cardiovascular disease | Activation | Caspase-3 | Neurotoxicity | Mitochondria | Reperfusion | Carotenoids | Ischemia | Rodents | Penicillin | Occupational health | Membrane potential | Pretreatment | Cardiology | Cardiovascular system | Caspase | Cardiomyocytes | Cultures | Pharmacology | Malondialdehyde | Hypotheses | Hospitals | Hypoxia | MPTP | Laboratory animals | Cytoplasm | Index Medicus
Journal Article
Plant, Cell & Environment, ISSN 0140-7791, 04/2014, Volume 37, Issue 4, pp. 886 - 898
Plant respiration responses to elevated CO 2 concentration ( [ CO 2 ] ) have been studied for three decades without consensus about the mechanism of response.... 
respiratory metabolism | genomic | transcriptome | rabidopsis | climate change | Climate change | Respiratory metabolism | Arabidopsis | Genomic | Transcriptome | ARABIDOPSIS-THALIANA | PHOTOSYNTHETIC ACCLIMATION | USE EFFICIENCY | PLANT RESPIRATION | PLANT SCIENCES | ATMOSPHERIC CARBON-DIOXIDE | DARK RESPIRATION | CENTRAL METABOLISM | LONG-TERM GROWTH | GENE-EXPRESSION | SOURCE LEAVES | Transcription, Genetic - drug effects | Arabidopsis - physiology | Electron Transport - drug effects | Electron Transport - radiation effects | Genes, Plant | Starch - metabolism | Transcription, Genetic - radiation effects | Citric Acid Cycle - radiation effects | Cell Respiration - radiation effects | Biomass | RNA, Messenger - metabolism | Arabidopsis - radiation effects | Cell Respiration - genetics | Light | Cell Respiration - drug effects | Mitochondria - radiation effects | Nitrogen - pharmacology | Plant Leaves - drug effects | Photosynthesis - radiation effects | Gene Expression Regulation, Plant - radiation effects | Arabidopsis - drug effects | RNA, Messenger - genetics | Citric Acid Cycle - drug effects | Mitochondria - metabolism | Plant Leaves - radiation effects | Mitochondria - drug effects | Arabidopsis - genetics | Gene Expression Regulation, Plant - drug effects | Analysis of Variance | Plant Leaves - genetics | Photosynthesis - drug effects | Carbon Dioxide - pharmacology | Plant Leaves - physiology | Arabidopsis thaliana | Global temperature changes | Phytochemistry | Protein biosynthesis | Genetic aspects | Genetic transcription | Photosynthesis | Atmospheric carbon dioxide | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 2014, Volume 23, Issue 17, pp. 4491 - 4509
A novel mutation in the alpha-Synuclein (alpha-Syn) gene "G51D" was recently identified in two familial cases exhibiting features of Parkinson's disease (PD)... 
WILD-TYPE | INCLUSION FORMATION | OXIDATIVE STRESS | HUMAN PLASMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | RAT-BRAIN NEURONS | MONOCLONAL-ANTIBODY | SOLUTION NMR-SPECTROSCOPY | PULSED ESR MEASUREMENTS | TRANSGENIC MICE | PHOSPHOLIPID-BINDING | Neurons - pathology | Humans | alpha-Synuclein - ultrastructure | Saccharomyces cerevisiae - drug effects | Protein Transport - drug effects | Brain - metabolism | Saccharomyces cerevisiae - metabolism | Cell Nucleus - metabolism | Protein Binding - drug effects | Sodium Dodecyl Sulfate - pharmacology | Cell Membrane - metabolism | Neurons - metabolism | alpha-Synuclein - genetics | Phosphorylation - drug effects | Buffers | Inclusion Bodies - metabolism | Neurons - drug effects | Protein Aggregation, Pathological - genetics | Cell Membrane - drug effects | Neuroblastoma - pathology | Protein Aggregates - drug effects | Cell Line | Parkinson Disease - pathology | Protein Structure, Secondary | Subcellular Fractions - drug effects | Cells, Cultured | Inclusion Bodies - drug effects | Mitochondria - metabolism | alpha-Synuclein - secretion | Mitochondria - drug effects | Parkinson Disease - genetics | Mutation - genetics | Subcellular Fractions - metabolism | alpha-Synuclein - chemistry | Brain - drug effects | Unilamellar Liposomes - metabolism | Nuclear Envelope - metabolism | Nuclear Envelope - drug effects | Cell Differentiation - drug effects | Brain - pathology | Cell Nucleus - drug effects | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2016, Volume 24, Issue 6, pp. 795 - 806
NAD availability decreases with age and in certain disease conditions. Nicotinamide mononucleotide (NMN), a key NAD intermediate, has been shown to enhance NAD... 
NAD | NAD+ precursor | insulin sensitivity | eye function | anti-aging | mitochondria | aging | nicotinamide mononucleotide | glucose metabolism | NMN | energy metabolism | precursor | LIFE-SPAN | STEM-CELLS | ACTIVATION | MITOCHONDRIAL | NAD BIOSYNTHESIS | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | RIBOSIDE | SIRT1 | ADIPOSE-TISSUE | CELL BIOLOGY | Darkness | Aging - drug effects | Male | Muscle, Skeletal - metabolism | Nicotinamide Mononucleotide - administration & dosage | Aging - genetics | Time Factors | Lipids - blood | Muscle, Skeletal - drug effects | Cell Respiration - drug effects | Myeloid Cells - drug effects | Weight Gain - drug effects | NAD - metabolism | Physical Conditioning, Animal | Food | Lymphocytes - metabolism | Insulin - pharmacology | Administration, Oral | Mice, Inbred C57BL | Mitochondria - metabolism | Mitochondria - drug effects | Gene Expression Regulation - drug effects | Eating - drug effects | Bone Density - drug effects | Animals | Aging - physiology | Lymphocytes - drug effects | Myeloid Cells - metabolism | Nicotinamide Mononucleotide - pharmacology | Drinking - drug effects | Nicotinamide Mononucleotide - blood | Energy Metabolism - drug effects | Niacinamide | Medical colleges | Exercise | Pharmacy | Genes | Body weight | Physiological aspects | Muscles | Mice | Ophthalmology | Gene expression | Index Medicus
Journal Article
植物学报:英文版, ISSN 1672-9072, 2016, Volume 58, Issue 8, pp. 737 - 748
The physiological role of plant mitochondrial glutathione peroxidases is scarcely known. This study attempted to elucidate the role of a rice mitochondrial... 
Oryza sativa | redox homeostasis | photochemistry | assimilation | glutathione peroxidase | Glutathione peroxidase | Redox homeostasis | Photochemistry | CO2 assimilation | ARABIDOPSIS-THALIANA | OXIDATIVE DAMAGE | JATROPHA-CURCAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | LEAVES | MECHANISMS | PLANT SCIENCES | SALT STRESS | STRESS TOLERANCE | SUPEROXIDE-DISMUTASE | Lipid Peroxidation - radiation effects | Gene Silencing - drug effects | Gases - metabolism | Glutathione - metabolism | Sodium Chloride - pharmacology | Gene Silencing - radiation effects | Biomass | Oryza - radiation effects | Stress, Physiological - radiation effects | Plant Roots - drug effects | Light | Lipid Peroxidation - drug effects | Mitochondria - radiation effects | Cell Membrane - metabolism | Oxidative Stress - radiation effects | Plant Leaves - drug effects | Plant Proteins - metabolism | Stress, Physiological - drug effects | Cell Membrane - drug effects | Cell Membrane - radiation effects | Photosynthesis - radiation effects | Glutathione Peroxidase - metabolism | Plant Roots - metabolism | Oryza - physiology | Mitochondria - metabolism | Plant Leaves - radiation effects | Mitochondria - drug effects | Oryza - drug effects | Hydrogen Peroxide - metabolism | Salinity | Phenotype | Plant Leaves - metabolism | Photosynthesis - drug effects | Oxidative Stress - drug effects | Plant Roots - radiation effects | Phytochemistry | Physiological aspects | Water use | Mitochondrial DNA | Plants | Photosynthesis | Index Medicus
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 11/2013, Volume 45, Issue 11, pp. 2553 - 2562
In order to find a novel photosensitizer to be used in photodynamic therapy for cancer treatment, we have previously showed that the cationic zinc(II)... 
Phthalocyanine | Bcl-2 family proteins | Photodynamic therapy | Apoptosis | Lysosomal proteases | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTEINE CATHEPSINS | CLEAVAGE | CELL BIOLOGY | PROGRAMMED CELL-DEATH | BAX | CYTOCHROME-C RELEASE | MEMBRANE PERMEABILIZATION | Cell Death - radiation effects | Reactive Oxygen Species - metabolism | Membrane Potential, Mitochondrial - radiation effects | Humans | Dermatitis, Phototoxic - pathology | Protein Transport - drug effects | Membrane Potential, Mitochondrial - drug effects | Photochemotherapy | Lysosomes - radiation effects | Caspases - metabolism | Lysosomes - metabolism | Mitochondria - radiation effects | Intracellular Membranes - radiation effects | Cell Death - drug effects | Signal Transduction - radiation effects | Cathepsins - antagonists & inhibitors | Radiation, Ionizing | Lysosomes - drug effects | Permeability - drug effects | Organometallic Compounds - toxicity | Cytochromes c - metabolism | bcl-2-Associated X Protein - metabolism | Indoles - toxicity | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Enzyme Activation - radiation effects | Permeability - radiation effects | Signal Transduction - drug effects | Cathepsins - metabolism | Dermatitis, Phototoxic - metabolism | Models, Biological | Protein Transport - radiation effects | Cell Line, Tumor | Organometallic Compounds - chemistry | Intracellular Membranes - drug effects | Indoles - chemistry | Intracellular Membranes - metabolism | Zinc | Phthalocyanins | Index Medicus | Proteins | Membranes | Pathways | Protease | Cationic | Lysosomes | Cleavage | Activation
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 07/2007, Volume 27, Issue 13, pp. 4953 - 4967
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
TRANSCRIPTIONAL COACTIVATOR PGC-1 | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | ACETYL-COA | OVEREXPRESSING SPERMIDINE/SPERMINE N-1-ACETYLTRANSFERASE | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | MUSCLE-CELLS | MICROARRAY DATA | TRANSGENIC MICE | CELL BIOLOGY | Gene Expression Regulation, Enzymologic - drug effects | Acetyltransferases - metabolism | Multienzyme Complexes - metabolism | Adipocytes - drug effects | Glucose Intolerance | AMP-Activated Protein Kinases | Oxidative Phosphorylation - drug effects | Adipose Tissue, White - cytology | Body Composition - drug effects | Isoenzymes - metabolism | Adenosine Triphosphate - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Food Deprivation | p38 Mitogen-Activated Protein Kinases - metabolism | Homeostasis - drug effects | Phosphorylation - drug effects | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Isoenzymes - genetics | Hydrogen Peroxide - pharmacology | Protein-Serine-Threonine Kinases - genetics | Mitochondria - metabolism | Multienzyme Complexes - genetics | Macrophages - cytology | Mitochondria - drug effects | Feeding Behavior - drug effects | Polyamines - metabolism | Macrophages - metabolism | Organ Size - drug effects | Animals | Adipocytes - metabolism | Fibroblasts - drug effects | Adipose Tissue, White - enzymology | Adipose Tissue, White - growth & development | Glucose - metabolism | Macrophages - drug effects | Trans-Activators - metabolism | Mice | Transcription Factors | Adipose Tissue, White - drug effects | Energy Metabolism - drug effects | Index Medicus | White/cytology/drug effects/enzymology/growth | Hydrogen Peroxide/pharmacology | Macrophages/cytology/drug effects/metabolism | Mitochondria/drug effects/metabolism | Fibroblasts/drug effects/metabolism | p38 Mitogen-Activated Protein Kinases/metabolism | MEDICIN OCH HÄLSOVETENSKAP | Homeostasis/drug effects | Multienzyme Complexes/genetics/metabolism | Protein-Serine-Threonine Kinases/genetics/metabolism | Trans-Activators/genetics/metabolism | Enzymologic/drug effects | Glucose/metabolism | Adipose Tissue | Feeding Behavior/drug effects | Organ Size/drug effects | Oxidative Phosphorylation/drug effects | MEDICAL AND HEALTH SCIENCES | development | Acetyltransferases/metabolism | Adipocytes/drug effects/metabolism | Gene Expression Regulation | Adenosine Triphosphate/metabolism | Body Composition/drug effects | Polyamines/metabolism | Energy Metabolism/drug effects | Isoenzymes/genetics/metabolism | Phosphorylation/drug effects
Journal Article
Planta, ISSN 0032-0935, 6/2013, Volume 237, Issue 6, pp. 1509 - 1525