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Journal Article
Annual Review of Biochemistry, ISSN 0066-4154, 6/2017, Volume 86, pp. 193 - 224
Autophagy and the ubiquitin-proteasome system are the two major quality control pathways responsible for cellular homeostasis. As such, they provide protection... 
xenophagy | proteasome | mitophagy | autophagy | chaperone | ubiquitination | aggrephagy | organelle homeostasis | UPS | p62-Keap1-Nrf2 | proteostasis | P62-Keap1-Nrf2 | Ubiquitination | Xenophagy | Proteostasis | Aggrephagy | Chaperone | Organelle homeostasis | Mitophagy | Autophagy | Proteasome | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | YEAST 26S PROTEASOME | QUALITY-CONTROL | SELECTIVE AUTOPHAGY | TRANSCRIPTION FACTOR NRF1 | MITOCHONDRIAL DYNAMICS | SYNUCLEIN IMPAIRS MACROAUTOPHAGY | N-TERMINAL DOMAIN | UBIQUITIN LIGASE MARCH5 | Molecular Chaperones - metabolism | Humans | Ubiquitin - metabolism | Homeostasis | Eukaryotic Cells - metabolism | Kelch-Like ECH-Associated Protein 1 - chemistry | Mitochondrial Degradation - genetics | Kelch-Like ECH-Associated Protein 1 - genetics | Proteolysis | NF-E2-Related Factor 2 - genetics | Autophagy - genetics | Sequestosome-1 Protein - chemistry | Sequestosome-1 Protein - metabolism | Signal Transduction | Gene Expression Regulation | Molecular Chaperones - genetics | Kelch-Like ECH-Associated Protein 1 - metabolism | Ubiquitin - genetics | Sequestosome-1 Protein - genetics | NF-E2-Related Factor 2 - metabolism | Protein Conformation | Eukaryotic Cells - cytology | NF-E2-Related Factor 2 - chemistry | Proteasome Endopeptidase Complex - metabolism | Physiological aspects | Autophagy (Cytology) | Genetic aspects | Research | Ubiquitin-proteasome system
Journal Article
Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 10/2014, Volume 58, Issue 10, pp. 1931 - 1940
Scope Dietary polyphenols are suggested to play a role in the prevention of Alzheimer's disease, of which accumulation of aggregated beta amyloid (Aβ) is a key... 
Amyloid β peptide | Caenorhabditis elegans | Alzheimer's disease | Autophagy | Proteasome | Unfolded protein response | ALZHEIMERS-DISEASE | MEDITERRANEAN DIET | FOOD SCIENCE & TECHNOLOGY | NEURODEGENERATION | MODEL | IMPAIRMENT | GENE-EXPRESSION | Amyloid beta peptide | PRECURSOR PROTEIN | STRESS | AGGREGATION | Humans | Caenorhabditis elegans Proteins - metabolism | Lysosomes - enzymology | Lysosomes - metabolism | RNA Interference | Alzheimer Disease - prevention & control | Amyloid beta-Peptides - genetics | Protein Aggregation, Pathological - prevention & control | Proteolysis | Amyloid beta-Peptides - metabolism | Quercetin - administration & dosage | Muscles - metabolism | Peptide Fragments - genetics | Disease Models, Animal | Nerve Tissue Proteins - antagonists & inhibitors | Paralysis - chemically induced | Peptide Fragments - metabolism | Protein Aggregation, Pathological - enzymology | Animals, Genetically Modified | Quercetin - therapeutic use | Unfolded Protein Response | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Amyloid beta-Peptides - antagonists & inhibitors | Antioxidants - therapeutic use | Animals | Caenorhabditis elegans Proteins - antagonists & inhibitors | Muscles - enzymology | Peptide Fragments - antagonists & inhibitors | Paralysis - prevention & control | Alzheimer Disease - metabolism | Antioxidants - administration & dosage | Proteasome Endopeptidase Complex - metabolism | Caenorhabditis elegans Proteins - genetics | Dietary Supplements | Protein Aggregation, Pathological - metabolism | Proteins | Analysis | Polyphenols | Genetic engineering | Mitochondrial DNA | Paralysis
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2018, Volume 20, Issue 3, pp. 233 - 242
Macroautophagy, initially described as a non-selective nutrient recycling process, is essential for the removal of multiple cellular components. In the past... 
ACTIVATE PARKIN | SIGNALING PATHWAYS | REGULATES MITOPHAGY | VACUOLE TARGETING PATHWAY | ENDOPLASMIC-RETICULUM | RECEPTOR-MEDIATED MITOPHAGY | TAGS PEROXISOMES | SACCHAROMYCES-CEREVISIAE | MITOCHONDRIAL QUALITY-CONTROL | PARKINSONS-DISEASE | CELL BIOLOGY | Proteins | Degradation | Receptors | Organelles | Autophagy | Phagocytosis | stress | mitophagy | receptor | vacuole | yeast
Journal Article