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Molecular Cell, ISSN 1097-2765, 01/2013, Volume 49, Issue 1, pp. 186 - 199
Journal Article
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 02/2013, Volume 41, Issue 4, pp. 2354 - 2369
Journal Article
Journal Article
Journal Article
Cell, ISSN 0092-8674, 11/2017, Volume 171, Issue 5, pp. 1072 - 1081.e10
Transcription in human mitochondria is driven by a single-subunit, factor-dependent RNA polymerase (mtRNAP). Despite its critical role in both expression and... 
Polymerase | Mitochondria | Transcription | TFAM | Initiation Complex | TFB2M | POLRMT | Initiation | TEFM | TRANSITION | RECOGNITION | ELONGATION COMPLEX | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | T7 RNA-POLYMERASE | PROMOTER | INHIBITOR | STRAND | RIBOSOME | CELL BIOLOGY | Methyltransferases - isolation & purification | Transcription Factors - chemistry | Humans | Methyltransferases - metabolism | DNA-Binding Proteins - metabolism | Mitochondrial Proteins - isolation & purification | Bacteriophage T7 - enzymology | Mitochondria - genetics | Mitochondrial Proteins - metabolism | Transcription, Genetic | Transcription Initiation, Genetic | DNA, Mitochondrial - chemistry | Amino Acid Sequence | Methyltransferases - chemistry | Promoter Regions, Genetic | DNA, Mitochondrial - metabolism | Gene Expression Regulation | Models, Molecular | Mitochondria - metabolism | DNA-Binding Proteins - isolation & purification | DNA-Binding Proteins - chemistry | Transcription Factors - metabolism | Multiprotein Complexes - chemistry | Sequence Alignment | Bacteriophage T7 - metabolism | Mitochondrial Proteins - chemistry | Transcription Factors - isolation & purification | DNA-Directed RNA Polymerases - metabolism | DNA replication | Analysis | Genes | Genomics | Crystals | Genetic research | DNA binding proteins | Genetic transcription | Structure | RNA polymerases | Cells | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e78648 - e78648
Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting approximately 1-2% of the general population over age 60. It is characterized by... 
RECESSIVE JUVENILE PARKINSONISM | DISEASE GENES | UBIQUITIN LIGASE | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIAL PATHOLOGY | PROTEIN INTERACTION NETWORKS | MUTATIONS | GENE ONTOLOGY | FUNCTIONAL SIMILARITY | DROSOPHILA | CELL-DEATH | Humans | Ubiquitin-Protein Ligases - metabolism | Parkinson Disease - genetics | Drosophila Proteins - metabolism | Nerve Tissue Proteins - genetics | Drosophila Proteins - isolation & purification | Nerve Tissue Proteins - metabolism | Animals | Nerve Tissue Proteins - isolation & purification | Cell Line, Tumor | Protein Binding | Ubiquitin-Protein Ligases - isolation & purification | Parkinson Disease - metabolism | Drosophila Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Drosophila melanogaster | Ubiquitin | Nervous system diseases | Parkinson's disease | Cell death | Genes | Genetic aspects | Medical screening | Binding proteins | Mass spectrometry | Protein-protein interactions | Protein binding | Basal ganglia | Immunoprecipitation | Ontology | Protein purification | Substantia nigra | Biology | Synuclein | Machinery | Data bases | Proteins | Depolarization | Mitochondria | Neurodegeneration | Protein folding | Cell cycle | Fusion protein | Bioinformatics | Informatics | Ubiquitin-protein ligase | Age | Movement disorders | Dopamine receptors | Dopamine | Purification | Neurodegenerative diseases | Neurons | Drosophila | Central nervous system diseases | Mass spectroscopy | Gene expression | Screens | Biological activity | Lewy bodies | Acids | Insects | Affinity | Parkin protein | Mutation | Protein interaction | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Nature Protocols, ISSN 1754-2189, 11/2006, Volume 1, Issue 4, pp. 1872 - 1878
We have shown that sample fractionation is an effective method for increasing the detection coverage of the proteome of complex samples, such as organs, by... 
MITOCHONDRIAL | EXPRESSION | MAP | MEMBRANE | MOUSE | BIOCHEMICAL RESEARCH METHODS | Proteomics - methods | Proteins - isolation & purification | Mass Spectrometry | Cell Fractionation - methods
Journal Article