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The Journal of clinical investigation, ISSN 0021-9738, 07/2010, Volume 120, Issue 7, pp. 2457 - 2473
Journal Article
Biochemical journal, ISSN 0264-6021, 12/2007, Volume 408, Issue 3, pp. 297 - 315
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | drug discovery | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | inhibitor specificity | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | anti-cancer drugs | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | protein kinase | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | kinase profiling | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Journal Article
Developmental cell, ISSN 1534-5807, 11/2012, Volume 23, Issue 5, pp. 1020 - 1031
Journal Article
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 11/2014, Volume 10, Issue 11, pp. 1937 - 1952
ACTB, actin, beta | MYD88, myeloid differentiation primary response 88 | PELI3 | CHX, cycloheximide | BECN1, Beclin 1, autophagy related | TICAM1, toll-like receptor adaptor molecule 1 | LPS | RIPK1, receptor (TNFRSF)-interacting serine-threonine kinase 1 | TUBB, tubulin, beta class I | PRRs, pattern recognition receptors | UBB, ubiquitin B | IRAKs, interleukin-1 receptor-associated kinases | HBSS, Hank's balanced salt solution | ATG7, autophagy-related 7 | MAP1LC3B, microtubule-associated protein 1 light chain 3 beta | TLRs, toll-like receptors | Baf A1, bafilomycin A | WT, wildtype | autophagy | TNF, tumor necrosis factor | MAPK14, mitogen-activated protein kinase 14 | NFKB, nuclear factor of kappa light polypeptide gene enhancer in B-cells | MAPK1/3, mitogen-activated protein kinase 1/3 | Epoxo, epoxomycin | TRAF6, TNF receptor-associated factor 6, E3 ubiquitin protein ligase | IL1B, interleukin 1, beta | MTOR, mechanistic target of rapamycin (serine/threonine kinase) | TABs, TGF-beta activated kinase 1/MAP3K7 binding protein 1/2/3 | Wortm, wortmannin | PELI3, pellino E3 ubiquitin protein ligase family member 3 | MAPK8/9, mitogen-activated protein kinase 8/9 | SQSTM1, sequestosome 1 | NFE2L2, nuclear factor, erythroid 2-like 2 | NLRP3, NLR family, pyrin domain containing 3 | LAMP2, lysosomal-associated membrane protein 2 | LPS, lipopolysaccharide | MAP3K14, mitogen-activated protein kinase kinase kinase 14 | MΦ, macrophages | Rapa, rapamycin | SQSTM1 | TBK1, TANK-binding kinase 1 | Torin2 | MAP3K7, mitogen-activated protein kinase kinase kinase 7 | Autophagy | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | Cytokines - metabolism | Signal Transduction | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Adenosine Triphosphatases - metabolism | Lipopolysaccharides - metabolism | Inflammation | Immunity, Innate | RNA, Messenger - metabolism | Toll-Like Receptor 4 - metabolism | Point Mutation | Macrophages - metabolism | Animals | Interleukin-1beta - metabolism | Sepsis - metabolism | Mice | Naphthyridines - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 08/2020, Volume 79, Issue 3, pp. 376 - 389.e8
Journal Article