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Apoptosis (London), ISSN 1360-8185, 3/2008, Volume 13, Issue 3, pp. 343 - 353
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2008, Volume 283, Issue 9, pp. 5533 - 5541
In response to diverse genotoxic stimuli ( e.g. UV and cisplatin), the mitogen-activated protein kinases ERK1/2, JNK1/2, and p38α/β... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Genome, Human - radiation effects | Mitogen-Activated Protein Kinase 8 - antagonists & inhibitors | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | DNA Repair - radiation effects | Genome, Human - drug effects | DNA Adducts - metabolism | Mitogen-Activated Protein Kinase 11 - metabolism | Flow Cytometry | Phosphorylation - drug effects | DNA Damage - drug effects | Cell Survival - drug effects | MAP Kinase Signaling System - radiation effects | DNA Repair - drug effects | Mitogen-Activated Protein Kinase 9 - metabolism | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Mitogen-Activated Protein Kinase 8 - metabolism | Mitogen-Activated Protein Kinase 11 - antagonists & inhibitors | Cell Survival - radiation effects | Ultraviolet Rays - adverse effects | Phosphorylation - radiation effects | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Mitogen-Activated Protein Kinase 9 - antagonists & inhibitors | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | DNA Damage - radiation effects | Cell Proliferation - radiation effects | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 1460-2105, 04/2011, Volume 103, Issue 8, pp. 645 - 661
Background Ionizing radiation (IR) is effectively used in cancer therapy. However, in subsets of patients, a few radioresistant cancer cells survive and cause disease relapse with metastatic progression... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Humans | Neoplasm Invasiveness - prevention & control | Radiation Tolerance | Receptors, Growth Factor - antagonists & inhibitors | NF-kappa B - metabolism | RNA, Messenger - metabolism | NF-kappa B - radiation effects | Receptors, Growth Factor - genetics | Proto-Oncogene Proteins c-met - radiation effects | Signal Transduction - radiation effects | Protein-Serine-Threonine Kinases - metabolism | Radiation, Ionizing | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - radiation effects | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - radiation effects | Receptors, Growth Factor - radiation effects | Proto-Oncogene Proteins c-met - drug effects | Ataxia Telangiectasia Mutated Proteins | Phosphorylation - radiation effects | Cell Line, Tumor | Mice | RNA, Small Interfering | Tumor Suppressor Proteins - radiation effects | Receptors, Growth Factor - metabolism | Neoplasms - metabolism | Proto-Oncogene Proteins c-met - metabolism | Apoptosis - radiation effects | Up-Regulation - radiation effects | Transcription, Genetic - radiation effects | Transplantation, Heterologous | Sulfones - pharmacology | DNA-Binding Proteins - metabolism | Chromatin Immunoprecipitation | Protein-Serine-Threonine Kinases - radiation effects | Tumor Suppressor Proteins - genetics | Polymerase Chain Reaction | Cell Cycle Proteins - genetics | Indoles - pharmacology | Neoplasms - radiotherapy | Gene Expression Regulation, Neoplastic - drug effects | In Situ Nick-End Labeling | Enzyme-Linked Immunosorbent Assay | Radiation-Sensitizing Agents - pharmacology | Gene Silencing | Protein-Serine-Threonine Kinases - genetics | DNA-Binding Proteins - genetics | Cell Survival - radiation effects | Cell Movement - radiation effects | Proto-Oncogene Proteins c-met - genetics | Blotting, Northern | Animals | NF-kappa B - genetics | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Receptors, Growth Factor - drug effects | DNA Damage - radiation effects | Mitogen-Activated Protein Kinases - metabolism | Ionizing radiation | Physiological aspects | Genetic aspects | Cancer invasiveness | Research | Gene expression | Radiotherapy | Health aspects | Radiation therapy | Kinases | Index Medicus
Journal Article
Cancer biology & therapy, ISSN 1538-4047, 08/2004, Volume 3, Issue 8, pp. 739 - 751
...; however only at higher concentrations did GST-MDA-7 reduce cell viability. The anti-proliferative and cytotoxic effects of GST-MDA-7 were enhanced by radiation in a greater than additive fashion that correlated with JNK1/2/3 activation... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | MDA-7 | Signaling | Glioblastoma | Radiation | Life Sciences & Biomedicine | Oncology | Science & Technology | Caspase 9 | Adjuvants, Immunologic - pharmacology | Caspase 8 | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Radiation Tolerance | JNK Mitogen-Activated Protein Kinases - metabolism | Genes, erbB-1 - physiology | Brain Neoplasms - metabolism | Interleukins - metabolism | Astrocytes - radiation effects | Mitogen-Activated Protein Kinase Kinases - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | MAP Kinase Kinase 4 | PTEN Phosphohydrolase | Adenoviridae - genetics | Glioblastoma - metabolism | Colony-Forming Units Assay | Interleukins - pharmacology | Tumor Cells, Cultured | Genes, Tumor Suppressor | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Astrocytes - drug effects | bcl-X Protein | Tumor Suppressor Proteins - metabolism | ErbB Receptors - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Radiation-Sensitizing Agents - pharmacology | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein | Enzyme Activation - drug effects | Caspase Inhibitors | Glioblastoma - therapy | Proto-Oncogene Proteins c-akt | Acetylcysteine - pharmacology | Brain Neoplasms - therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Phosphoric Monoester Hydrolases - metabolism | Cell Proliferation - radiation effects | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2009, Volume 15, Issue 9, pp. 3050 - 3057
.... The MAP kinase pathway is also activated after exposure to ionizing radiation. We investigated the effects of AZD6244 (ARRY-142886... 
RAS | MEK | radiosensitizer | Life Sciences & Biomedicine | Oncology | Science & Technology | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Lung Neoplasms - pathology | Male | Pancreatic Neoplasms - drug therapy | Female | Phosphorylation - drug effects | Prostatic Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - pathology | Prostatic Neoplasms - pathology | Tumor Stem Cell Assay | Lung Neoplasms - enzymology | Cell Cycle - radiation effects | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Pancreatic Neoplasms - pathology | Radiation-Sensitizing Agents - pharmacology | Adenocarcinoma - enzymology | Pancreatic Neoplasms - enzymology | Adenocarcinoma - drug therapy | Blotting, Western | Xenograft Model Antitumor Assays | Phosphorylation - radiation effects | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mice, Nude | X-Rays | Fluorescent Antibody Technique | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Cell Cycle - drug effects | In Vitro Techniques | Cell Proliferation - radiation effects | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2010, Volume 285, Issue 2, pp. 1283 - 1295
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 07/2002, Volume 22, Issue 13, pp. 4522 - 4534
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transcription Factor AP-1 - drug effects | Retinoid X Receptors | Tetradecanoylphorbol Acetate - pharmacology | Transcription Factor AP-1 - genetics | Humans | Mitogen-Activated Protein Kinase Kinases - radiation effects | Nuclear Receptor Co-Repressor 1 | Glycogen Synthase Kinase 3 | Transcription Factor AP-1 - metabolism | HeLa Cells - radiation effects | MAP Kinase Kinase 1 | Receptors, Retinoic Acid - genetics | Transcription Factors - drug effects | Glycogen Synthase Kinases | Calcium-Calmodulin-Dependent Protein Kinases - drug effects | Mitogen-Activated Protein Kinase Kinases - metabolism | MAP Kinase Kinase 4 | Ultraviolet Rays | Protein-Serine-Threonine Kinases - radiation effects | Trans-Activators - genetics | Nuclear Proteins - genetics | Dimerization | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Tretinoin - pharmacology | Receptors, Retinoic Acid - drug effects | Promoter Regions, Genetic | Response Elements | CREB-Binding Protein | Enzyme Inhibitors - pharmacology | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Receptors, Retinoic Acid - metabolism | DNA - metabolism | Transcription Factors - genetics | HeLa Cells - drug effects | Transcription Factors - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinase Kinases - drug effects | Protein-Serine-Threonine Kinases - drug effects | Anisomycin - pharmacology | Mitogen-Activated Protein Kinases - genetics | Trans-Activators - metabolism | Mutation | Retinoic Acid Receptor alpha | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Mitogen-Activated Protein Kinases - metabolism | AP1 protein | Index Medicus | Transcriptional Regulation
Journal Article