X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (43849) 43849
Book Chapter (63) 63
Publication (26) 26
Dissertation (18) 18
Government Document (14) 14
Web Resource (12) 12
Book / eBook (9) 9
Newsletter (6) 6
Book Review (1) 1
Conference Proceeding (1) 1
Magazine Article (1) 1
Reference (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (35379) 35379
life sciences & biomedicine (33898) 33898
animals (28009) 28009
humans (21675) 21675
mitogen-activated protein kinases - metabolism (14074) 14074
biochemistry & molecular biology (12795) 12795
mice (12256) 12256
phosphorylation (11848) 11848
signal transduction (10189) 10189
rats (9865) 9865
cells, cultured (9604) 9604
cell biology (8914) 8914
male (8041) 8041
p38 mitogen-activated protein kinases - metabolism (7157) 7157
mitogen-activated protein kinase 1 - metabolism (6993) 6993
cell line (6404) 6404
enzyme activation (6211) 6211
enzyme inhibitors - pharmacology (6071) 6071
signal transduction - physiology (5466) 5466
apoptosis (5177) 5177
female (5011) 5011
mitogen-activated protein kinase 3 - metabolism (4954) 4954
signal transduction - drug effects (4918) 4918
neurosciences (4343) 4343
neurosciences & neurology (4236) 4236
cell line, tumor (3854) 3854
blotting, western (3845) 3845
jnk mitogen-activated protein kinases - metabolism (3774) 3774
rats, sprague-dawley (3661) 3661
physiology (3649) 3649
phosphorylation - drug effects (3581) 3581
p38 mitogen-activated protein kinases (3555) 3555
protein kinases (3344) 3344
enzyme activation - drug effects (3339) 3339
apoptosis - drug effects (3337) 3337
map kinase signaling system - physiology (3290) 3290
proteins (3214) 3214
transfection (3203) 3203
mitogen-activated protein kinases (3131) 3131
mitogen-activated protein kinase 3 (3129) 3129
kinases (3081) 3081
nf-kappa b - metabolism (2995) 2995
jnk mitogen-activated protein kinases (2967) 2967
mitogen-activated protein kinase (2951) 2951
dose-response relationship, drug (2904) 2904
time factors (2896) 2896
map kinase signaling system - drug effects (2852) 2852
mitogen-activated protein kinase kinases - metabolism (2812) 2812
abridged index medicus (2750) 2750
gene expression (2744) 2744
research (2742) 2742
mitogen-activated protein kinases - antagonists & inhibitors (2696) 2696
oncology (2672) 2672
protein-serine-threonine kinases - metabolism (2610) 2610
mice, inbred c57bl (2575) 2575
map kinase signaling system (2566) 2566
mitogen-activated protein kinases - physiology (2527) 2527
biophysics (2509) 2509
endocrinology & metabolism (2492) 2492
phosphatidylinositol 3-kinases - metabolism (2481) 2481
map kinase (2439) 2439
immunology (2435) 2435
physiological aspects (2404) 2404
flavonoids - pharmacology (2398) 2398
rna, messenger - metabolism (2397) 2397
calcium-calmodulin-dependent protein kinases - metabolism (2315) 2315
research article (2264) 2264
pharmacology & pharmacy (2252) 2252
imidazoles - pharmacology (2247) 2247
pyridines - pharmacology (2244) 2244
analysis (2168) 2168
apoptosis - physiology (2111) 2111
cell proliferation (2072) 2072
molecular sequence data (2048) 2048
mice, knockout (2029) 2029
extracellular signal-regulated map kinases - metabolism (2026) 2026
reactive oxygen species - metabolism (1955) 1955
inflammation (1942) 1942
protein binding (1922) 1922
tumor cells, cultured (1905) 1905
gene expression regulation (1899) 1899
proto-oncogene proteins c-akt - metabolism (1847) 1847
amino acid sequence (1800) 1800
p38 mitogen-activated protein kinases - antagonists & inhibitors (1783) 1783
mitogen-activated protein kinases - genetics (1760) 1760
oxidative stress (1759) 1759
models, biological (1754) 1754
mutation (1748) 1748
mapk (1746) 1746
reverse transcriptase polymerase chain reaction (1717) 1717
rats, wistar (1698) 1698
protein-tyrosine kinases - metabolism (1689) 1689
proto-oncogene proteins - metabolism (1675) 1675
disease models, animal (1667) 1667
protein kinase c - metabolism (1649) 1649
extracellular signal-regulated kinase (1606) 1606
cell survival - drug effects (1603) 1603
protein kinase inhibitors - pharmacology (1586) 1586
calcium - metabolism (1564) 1564
cell proliferation - drug effects (1563) 1563
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (43795) 43795
Japanese (475) 475
Chinese (273) 273
Russian (28) 28
French (23) 23
Portuguese (17) 17
Polish (10) 10
Korean (9) 9
Spanish (9) 9
Dutch (6) 6
German (5) 5
Norwegian (3) 3
Italian (2) 2
Czech (1) 1
Danish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Apoptosis (London), ISSN 1360-8185, 3/2008, Volume 13, Issue 3, pp. 343 - 353
Journal Article
Journal Article
Biochemical journal, ISSN 1470-8728, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | drug discovery | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | inhibitor specificity | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | anti-cancer drugs | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | protein kinase | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | kinase profiling | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Leukemia, ISSN 1476-5551, 04/2011, Volume 25, Issue 7, pp. 1080 - 1094
The Ras/Raf/mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK... 
targeted therapy | Ras | therapeutic sensitivity | Raf | resistance | ERK | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | ras Proteins - genetics | MAP Kinase Signaling System - physiology | Mitogen-Activated Protein Kinase Kinases - genetics | Apoptosis - drug effects | raf Kinases - antagonists & inhibitors | Humans | Neoplasm Proteins - physiology | Mitogen-Activated Protein Kinase Kinases - physiology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - genetics | Gene Expression Regulation, Leukemic - genetics | raf Kinases - physiology | MAP Kinase Signaling System - genetics | Drug Design | Antineoplastic Agents - pharmacology | Extracellular Signal-Regulated MAP Kinases - physiology | Neoplasm Proteins - genetics | raf Kinases - genetics | ras Proteins - physiology | Cell Division - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | ras Proteins - antagonists & inhibitors | Gene Expression Regulation, Leukemic - drug effects | Leukemia - drug therapy | Cell Division - drug effects | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | MAP Kinase Signaling System - drug effects | Models, Biological | Phosphatidylinositol 3-Kinases - physiology | Apoptosis - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Chemotherapy | Extracellular signal-regulated kinases | Leukemia | Physiological aspects | Genetic aspects | Research | Drug therapy | Health aspects | Mitogen-activated protein kinases | Cancer | Index Medicus
Journal Article