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Apoptosis (London), ISSN 1360-8185, 3/2008, Volume 13, Issue 3, pp. 343 - 353
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 09/2017, Volume 77, Issue 17, pp. 4602 - 4612
Identifying critical factors involved in the metastatic progression of hepatocellular carcinoma (HCC) may offer important therapeutic opportunities. Here, we... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Prognosis | Humans | Lung Neoplasms - metabolism | Tumor Protein p73 - genetics | Gene Expression Profiling | Tumor Protein p73 - metabolism | Heat-Shock Proteins - genetics | Neoplasm Metastasis | Lung Neoplasms - secondary | Carcinoma, Hepatocellular - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Dual-Specificity Phosphatases - genetics | Liver Neoplasms - pathology | Tumor Cells, Cultured | Lung Neoplasms - genetics | Liver Neoplasms - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Dual-Specificity Phosphatases - metabolism | Heat-Shock Proteins - metabolism | Mitogen-Activated Protein Kinase Phosphatases - genetics | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Mice, Nude | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Protein Array Analysis | Mice | Mice, Inbred BALB C | Carcinoma, Hepatocellular - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinase Phosphatases - metabolism | Liver | Extracellular signal-regulated kinase | Hepatocellular carcinoma | Metastasis | Metastases | Liver cancer | Signal transduction | Signaling | Stress response | Binding sites | Cellular stress response | Tumors | Apoptosis | Cancer | Index Medicus | Liver Neoplasms | Lung Neoplasms | Life Sciences | Tumor Protein p73 | Heat-Shock Proteins | Mitogen-Activated Protein Kinase Phosphatases | Carcinoma, Hepatocellular | Dual-Specificity Phosphatases | Mitogen-Activated Protein Kinase 1 | Mitogen-Activated Protein Kinase 3 | Carrier Proteins
Journal Article
Oncogene, ISSN 1476-5594, 05/2007, Volume 26, Issue 22, pp. 3227 - 3239
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 4, pp. 893 - 902.e2
Background Many airway cells manifest signs of chronic activation in asthma. The mechanism of this chronic activation is unknown. Objectives We sought to study... 
Allergy and Immunology | mitogen-activated protein kinase | chemokines | epithelial function | bronchial biopsy | Asthma | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Phosphorylation | Bronchi - enzymology | Humans | Middle Aged | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Enzyme Induction - immunology | MAP Kinase Signaling System - immunology | Enzyme Activation - immunology | Respiratory Mucosa - pathology | Chemokines - antagonists & inhibitors | Mitogen-Activated Protein Kinase 3 - biosynthesis | Adult | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Bronchi - pathology | Respiratory Mucosa - secretion | Chemokines - biosynthesis | Chemokines - secretion | Mitogen-Activated Protein Kinase 1 - physiology | p38 Mitogen-Activated Protein Kinases - physiology | Asthma - enzymology | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Respiratory Mucosa - enzymology | Mitogen-Activated Protein Kinase 3 - physiology | Mitogen-Activated Protein Kinase 1 - biosynthesis | Mitogen-Activated Protein Kinase 3 - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinases - physiology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Asthma - pathology | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Protein kinases | Proteins | Studies | Signal transduction | Cell culture | Rodents | Cloning | Smooth muscle | Kinases | Index Medicus | Abridged Index Medicus
Journal Article
Nature chemical biology, ISSN 1552-4469, 09/2014, Volume 10, Issue 10, pp. 853 - 860
Activation of the ERK pathway is a hallmark of cancer, and targeting of upstream signaling partners led to the development of approved drugs. Recently,... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Gene Expression Regulation, Neoplastic | Intracellular Signaling Peptides and Proteins - metabolism | Piperazines - chemistry | Mitogen-Activated Protein Kinase 1 - chemistry | Enzyme Inhibitors - chemistry | Mitogen-Activated Protein Kinase 1 - genetics | Mitogen-Activated Protein Kinase 8 - genetics | Antineoplastic Agents - pharmacology | Mitogen-Activated Protein Kinase 3 - chemistry | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Gene Expression | Indazoles - chemistry | Mitogen-Activated Protein Kinase 3 - genetics | Protein Structure, Secondary | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Mitogen-Activated Protein Kinase 8 - chemistry | Mitogen-Activated Protein Kinase 8 - metabolism | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Antineoplastic Agents - chemistry | Piperazines - pharmacology | Indazoles - pharmacology | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Intracellular Signaling Peptides and Proteins - chemistry | Cell Line, Tumor | Protein Binding | Protein-Serine-Threonine Kinases - chemistry | Kinetics | Mitogen-Activated Protein Kinase 1 - metabolism | Signal transduction | Binding sites | Pharmaceutical sciences | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 2/2006, Volume 103, Issue 6, pp. 1705 - 1710
Amino acid racemases catalyze the stereoinversion of the chiral Cα to produce the D-enantiomers that participate in biological processes, such as cell wall... 
T lymphocytes | Enzymes | Solvents | B lymphocytes | Atoms | Amino acids | Biochemistry | Catalysis | Monomers | Crystal structure | Epimerases | Titration calorimetry | Enzyme-inhibitor complex | B cell mitogen | Pyridoxal phosphate-independent proline racemase | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Mitogens - pharmacology | Amino Acid Isomerases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mitogens - metabolism | Models, Molecular | Crystallography, X-Ray | Amino Acid Isomerases - pharmacology | Pyrrolidines - chemistry | Trypanosoma cruzi - enzymology | Thermodynamics | Animals | Amino Acid Isomerases - metabolism | Amino Acid Isomerases - chemistry | Lymphocytes - drug effects | Mitogens - genetics | Protein Structure, Quaternary | Cell Proliferation - drug effects | Mice | Binding Sites | Mitogens - chemistry | Volumetric analysis | Prokaryotes | Analysis | Crystals | Physiological aspects | Genetic aspects | Structure | Mitogens | Index Medicus | Lymphocytes/drug effects | Mitogens/metabolism | Mitogens/genetics | Trypanosoma cruzi/enzymology | Enzyme Inhibitors/pharmacology | Mitogens/pharmacology | Life Sciences | Biomolecules | Pyrrolidines/chemistry | Cell Proliferation/drug effects | Amino Acid Isomerases/antagonists & inhibitors | Biochemistry, Molecular Biology | Mitogens/chemistry | Amino Acid Isomerases/pharmacology | Amino Acid Isomerases/metabolism | Amino Acid Isomerases/chemistry | Biological Sciences | titration calorimetry | enzyme–inhibitor complex | pyridoxal phosphate-independent proline racemase | epimerases
Journal Article