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European Journal of Neuroscience, ISSN 0953-816X, 04/2004, Volume 19, Issue 7, pp. 1826 - 1836
A major goal of research on addiction is to identify the molecular mechanisms of long-lasting behavioural alterations induced by drugs of abuse. Cocaine and... 
Nucleus accumbens | Drug of abuse | D1 receptors | Dopamine | CD-1 mice | Extended amygdala | NEUROCHEMICAL SENSITIZATION | CONDITIONED PLACE PREFERENCE | BEHAVIORAL SENSITIZATION | nucleus accumbens | SYNAPTIC PLASTICITY | NEUROSCIENCES | MICE LACKING | drug of abuse | MEDIATED TRANSCRIPTION | PSYCHOMOTOR STIMULANT | SINGLE EXPOSURE | extended amygdala | LONG-TERM POTENTIATION | dopamine | SIGNAL-REGULATED KINASE | Central Nervous System Stimulants - pharmacology | Analgesics, Non-Narcotic - pharmacology | Analgesics, Opioid - pharmacology | Male | Nicotine - pharmacology | Brain - metabolism | Scopolamine Hydrobromide - pharmacology | Desipramine - pharmacology | Muscarinic Antagonists - pharmacology | Caffeine - pharmacology | Neurons - metabolism | Dronabinol - pharmacology | Neurons - drug effects | Nicotinic Agonists - pharmacology | Fluoxetine - pharmacology | Brain - cytology | Morphine - pharmacology | Benzazepines - pharmacology | Enzyme Activation - drug effects | Brain - drug effects | Immunohistochemistry - methods | Cocaine - pharmacology | Animals | Dopamine Antagonists - pharmacology | Adrenergic Uptake Inhibitors - pharmacology | Mice | Serotonin Uptake Inhibitors - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Index Medicus | Life Sciences | Cognitive Sciences | Neurons and Cognition
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2003, Volume 462, Issue 1, pp. 193 - 198
The cytokine interleukin-17 may play a role in the recruitment of airway neutrophils, and interleukin-17 protein is increased in the airways of patients with... 
C-X-C chemokine | Interleukin-17 | Bronchial epithelial cell | human | Human | ACTIVATION | PROTEIN | MECHANISMS | CYTOKINE | NEUTROPHIL RECRUITMENT | bronchial epithelial cell, human | interleukin-17 | IN-VITRO | IL-17 | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | AIRWAYS | CYCLOSPORINE | Epithelial Cells - metabolism | Albuterol - pharmacology | Cyclosporine - pharmacology | Epithelial Cells - drug effects | Humans | Receptors, Glucocorticoid - metabolism | Interleukin-17 - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Bronchi - drug effects | Dose-Response Relationship, Drug | Calcineurin Inhibitors | Bronchi - metabolism | Interleukin-8 - secretion | Flavonoids - pharmacology | Intercellular Signaling Peptides and Proteins - secretion | Receptors, Adrenergic, beta - drug effects | Receptors, Adrenergic, beta - metabolism | Receptors, Glucocorticoid - drug effects | Bronchi - cytology | Chemotactic Factors - secretion | p38 Mitogen-Activated Protein Kinases | Chemokines - secretion | Enzyme Inhibitors - pharmacology | Adrenergic beta-Agonists - pharmacology | Imidazoles - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Chemokines, CXC - secretion | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Chemokine CXCL1 | Hydrocortisone - pharmacology | Pyridines - pharmacology | Chemokine CXCL6 | Cell Line, Transformed | Index Medicus | Chemokines/secretion | Albuterol/pharmacology | Flavonoids/pharmacology | Adrenergic | beta/drug effects/metabolism | Epithelial Cells/drug effects/metabolism | Enzyme Inhibitors/pharmacology | Transformed | Adrenergic beta-Agonists/pharmacology | Ca(2+)-Calmodulin Dependent Protein Kinase/antagonists & inhibitors | Receptors | Imidazoles/pharmacology | Chemotactic Factors/secretion | Cyclosporine/pharmacology | Lungmedicin och allergi | Respiratory Medicine and Allergy | Bronchi/cytology/drug effects/metabolism | Drug | Intercellular Signaling Peptides and Proteins/secretion | Cell Line | P-Glycoprotein/antagonists & inhibitors | Interleukin-8/secretion | Hydrocortisone/pharmacology | Glucocorticoid/drug effects/metabolism | CXC/secretion | Interleukin-17/pharmacology | Mitogen-Activated Protein Kinases/antagonists & inhibitors | Calcineurin/antagonists & inhibitors | Dose-Response Relationship | Chemokines | Pyridines/pharmacology
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 08/2014, Volume 73, pp. 51 - 59
Microglia are the resident immune cells in the brain. Microglial activation is characteristic of several inflammatory and neurodegenerative diseases including... 
Peroxynitrite | Free radicals | Protein radical | Inducible nitric oxide synthase | Lipopolysaccharide | Nitrone adducts | Parkinson disease | Microglia | NADPH OXIDASE | OXIDATIVE STRESS | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INOS EXPRESSION | KAPPA-B | LIPOPOLYSACCHARIDE-ACTIVATED MICROGLIA | REACTIVE OXYGEN | ENDOCRINOLOGY & METABOLISM | GENERATION | TYROSINE NITRATION | PARKINSONS-DISEASE | Microglia - metabolism | Metalloporphyrins - pharmacology | Lipopolysaccharides | Thiocarbamates - pharmacology | RNA Interference | Nitric Oxide Synthase Type II - antagonists & inhibitors | Spin Trapping | Acetophenones - pharmacology | Free Radicals - metabolism | Proline - pharmacology | Microglia - cytology | NG-Nitroarginine Methyl Ester - pharmacology | NF-kappa B - antagonists & inhibitors | Proline - analogs & derivatives | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Antioxidants - pharmacology | Neurodegenerative Diseases - metabolism | Coumarins - pharmacology | Animals | Nitric Oxide Synthase Type II - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Peroxynitrous Acid - metabolism | Amidines - pharmacology | Mice | Pyridines - pharmacology | RNA, Small Interfering | Benzylamines - pharmacology | Cell Line, Transformed | Boronic Acids - pharmacology | Nitric Oxide Synthase Type II - metabolism | Nitration | Nervous system diseases | Multiple sclerosis | Analysis | Nitric oxide | Environmental health | Physiological aspects | Alzheimer's disease | Index Medicus | Inducible nitric | oxide synthase | LPS | Parkinson’s disease
Journal Article
Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 7, pp. 726 - 733
Altered gap junction coupling of cardiac myocytes during ischemia may contribute to development of lethal arrhythmias. The phosphoprotein connexin 43 (Cx43) is... 
Ischemia | Gap junctions | Glycolysis | Okadaic acid | Protein phosphatases | Connexin43 | Protein phosphorylation | AMP kinase | gap junctions | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | connexin43 | PHOSPHORYLATION | GAP JUNCTIONAL COMMUNICATION | glycolysis | CARDIAC MYOCYTES | ACTIN GENE | protein phosphorylation | okadaic acid | ischemia | IN-VITRO | INTERCELLULAR COMMUNICATION | PERIPHERAL VASCULAR DISEASE | JUN KINASE | protein phosphatases | RAT VENTRICULAR MYOCYTES | HEMATOLOGY | ADRENERGIC REGULATION | Okadaic Acid - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Recombinant Fusion Proteins - physiology | Myocardial Contraction - drug effects | Brefeldin A - pharmacology | Phenanthridines - pharmacology | Antimycin A - pharmacology | Aminoimidazole Carboxamide - pharmacology | Cell Hypoxia | Ribonucleotides - pharmacology | Alkaloids | Protein Processing, Post-Translational - drug effects | Adenosine Triphosphate - metabolism | Deoxyglucose - pharmacology | Tacrolimus - pharmacology | Indoles - pharmacology | Flavonoids - pharmacology | Potassium Cyanide - pharmacology | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Ouabain - pharmacology | Cells, Cultured - drug effects | Connexin 43 - metabolism | Rats | Imidazoles - pharmacology | Cycloheximide - pharmacology | Pyrroles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Benzophenanthridines | JNK Mitogen-Activated Protein Kinases - physiology | Myocytes, Cardiac - metabolism | Cells, Cultured - metabolism | Pyridines - pharmacology | Carbazoles - pharmacology | Staurosporine - pharmacology | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2000, Volume 118, Issue 6, pp. 1149 - 1156
Circulating levels of angiotensin II (ANGII), a powerful vasoconstrictor factor, are frequently increased in chronic liver diseases. In these conditions,... 
FAT-STORING CELLS | RAT-LIVER | GLOMERULAR MESANGIAL CELLS | DEPENDENT CONTRACTILITY | NITRIC-OXIDE | GROWTH-FACTOR | ITO CELLS | GASTROENTEROLOGY & HEPATOLOGY | SMOOTH-MUSCLE CELLS | PORTAL-HYPERTENSION | ALDOSTERONE SYSTEM | Receptor, Angiotensin, Type 1 | Receptors, Angiotensin - metabolism | Receptor, Angiotensin, Type 2 | Antihypertensive Agents - pharmacology | Iodine Radioisotopes | Liver - enzymology | Humans | Penicillamine - analogs & derivatives | Sodium Nitrite - pharmacology | Liver - drug effects | Thymidine - pharmacology | Nitric Oxide Donors - pharmacology | Radioligand Assay | Thymidine - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Dinoprostone - pharmacology | Angiotensin II - pharmacology | Angiotensin II - metabolism | Cell Size - drug effects | Penicillamine - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Losartan - pharmacology | Rats | Imidazoles - pharmacology | Cell Division - drug effects | Indomethacin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Animals | Vasoconstrictor Agents - metabolism | Liver - cytology | Pyridines - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Cell research | Liver diseases | Platelet-derived growth factor | Prostaglandins E | Nitric oxide | Angiotensin | Physiological aspects | Bookbinding | DNA synthesis | Peptide hormones | Protein kinases | Index Medicus | Abridged Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2011, Volume 440, Issue 3, pp. 355 - 365
Binding of specific microbial epitopes [MAMPs (microbe-associated molecular patterns)] to PRRs (pattern recognition receptors) and subsequent receptor kinase... 
Ionotropic glutamate receptor channel | Elicitor | Microbe-associated molecular pattern | Calcium channel | Calcium signature | Plant immunity | calcium channel | calcium signature | DEFENSE | GATED ION-CHANNEL | microbe-associated molecular pattern | SIGNATURES | elicitor | BIOCHEMISTRY & MOLECULAR BIOLOGY | CA2+ CHANNELS | PLANT-CELLS | ionotropic glutamate receptor channel | PLASMA-MEMBRANE | ROOT HAIRS | PERCEPTION | GENES | PATTERN-RECOGNITION RECEPTORS | plant immunity | Calcium Channels - metabolism | Seedlings - genetics | Type C Phospholipases - metabolism | Type C Phospholipases - antagonists & inhibitors | Arabidopsis Proteins - metabolism | Diltiazem - pharmacology | Estrenes - pharmacology | Plants, Genetically Modified | Pyrrolidinones - pharmacology | Gene Expression Regulation, Plant | Neomycin - pharmacology | Transcription, Genetic | Kynurenic Acid - pharmacology | Dideoxyadenosine - pharmacology | Arabidopsis Proteins - genetics | Nifedipine - pharmacology | Arabidopsis - drug effects | Receptors, Ionotropic Glutamate - metabolism | Aequorin - chemistry | Seedlings - drug effects | Calcium Channel Blockers - pharmacology | Chitin - pharmacology | Verapamil - pharmacology | Arabidopsis - metabolism | Arabidopsis - genetics | Receptors, Pattern Recognition | Bacterial Proteins - pharmacology | Calcium Signaling - drug effects | Alloxan - pharmacology | Mitogen-Activated Protein Kinases - genetics | Enzyme Activation | Arabidopsis Proteins - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Seedlings - metabolism | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 12/2009, Volume 105, Issue 12, pp. 1204 - 1212
RATIONALE:Angiotensin (Ang) II–induced apoptosis was reported to be mediated by different signaling molecules. Whether these molecules are either... 
Reactive oxygen species | CaMKII | Angiotensin II | Apoptosis | CARDIAC & CARDIOVASCULAR SYSTEMS | P38 MAPK | INHIBITION PROTECTS | apoptosis | VENTRICULAR MYOCYTES | CELL-DEATH | PHOSPHOLAMBAN PHOSPHORYLATION | HEART-DISEASE | METHIONINE OXIDATION | angiotensin II | reactive oxygen species | PERIPHERAL VASCULAR DISEASE | INDEPENDENT ACTIVATION | HEMATOLOGY | Free Radical Scavengers - pharmacology | Tiopronin - pharmacology | Reactive Oxygen Species - metabolism | Rats, Wistar | Species Specificity | Apoptosis - drug effects | Calcium - metabolism | NADPH Oxidases - metabolism | Peptides - genetics | Myocytes, Cardiac - enzymology | Time Factors | Egtazic Acid - analogs & derivatives | p38 Mitogen-Activated Protein Kinases - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Cats | Calmodulin - metabolism | Angiotensin II - metabolism | Cell Survival | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Chelating Agents - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Peptides - pharmacology | Myocytes, Cardiac - pathology | Animals | Egtazic Acid - pharmacology | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Enzyme Activation | Oxidative Stress - drug effects | Benzylamines - pharmacology | Calmodulin - antagonists & inhibitors | Index Medicus
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2009, Volume 296, Issue 2, pp. 470 - 479
Bacterial endotoxin lipopolysaccharide (LPS) is responsible for the multiorgan dysfunction that characterizes septic shock and is causal in the myocardial... 
Green fluorescent protein- Microtubule-associated protein light chain 3 | Lipopolysaccharide | Oxidative stress | Hl-1 cardiac myocyte | TRANSCRIPTIONAL ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | HL-1 cardiac myocyte | CARDIAC MYOCYTES | NECROSIS-FACTOR-ALPHA | MYOCARDIAL DEPRESSION | PROGRAMMED CELL-DEATH | ENDOTOXEMIC RATS | SCAVENGER RECEPTOR | green fluorescent protein-microtubule-associated protein light chain 3 | SEPTIC SHOCK | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | lipopolysaccharide | NF-KAPPA-B | oxidative stress | Tumor Necrosis Factor-alpha - metabolism | Mitochondria, Heart - metabolism | Glutathione - metabolism | Mitochondria, Heart - pathology | Nitric Oxide Synthase - antagonists & inhibitors | omega-N-Methylarginine - pharmacology | Mitochondria, Heart - drug effects | Nitroprusside - pharmacology | Autophagy - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Donors - pharmacology | Cytoprotection | Animals, Newborn | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Sirolimus - pharmacology | Hydrogen Peroxide - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide Synthase - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Signal transduction | Bacteria | Oxidation | Biochemistry | Cytokines | Sugar | Index Medicus
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2014, Volume 40, Issue 7, pp. 937 - 942
Abstract Introduction Biodentine (Septodont, Saint-Maur-des-Fossès, France), a new tricalcium silicate cement formulation, has been introduced as a bioactive... 
Endocrinology & Metabolism | Dentistry | Biodentine | biosilicate cement | calcium-/calmodulin-dependent protein kinase II | mitogen-activated protein kinase pathway | pathway | human dental pulp stem cells | nuclear factor-kappa B pathway | BONE-MARROW | MINERAL TRIOXIDE AGGREGATE | IN-VITRO | REPAIR | DENTISTRY, ORAL SURGERY & MEDICINE | NF-KAPPA-B | EXPRESSION | SILICATE | Nitriles - pharmacology | Humans | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - drug effects | Integrin-Binding Sialoprotein - analysis | Extracellular Matrix Proteins - analysis | Pyrrolidines - pharmacology | Young Adult | Thiocarbamates - pharmacology | Phosphoproteins - analysis | Alkaline Phosphatase - analysis | Adult | Cell Culture Techniques | Pulp Capping and Pulpectomy Agents - pharmacology | Osteocalcin - analysis | Calcium Compounds - pharmacology | Silicates - pharmacology | Butadienes - pharmacology | NF-kappa B - antagonists & inhibitors | Dental Pulp - cytology | Dental Pulp - drug effects | Imidazoles - pharmacology | Sulfonamides - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Anthracenes - pharmacology | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Adolescent | Odontoblasts - drug effects | Stem Cells - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Sialoglycoproteins - analysis | Benzylamines - pharmacology | NF-kappa B - drug effects | Cell differentiation | Mitogens | Protein kinases | Calmodulin | Stem cells
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2014, Volume 193, Issue 4, pp. 1954 - 1965
Canonical neutrophil antimicrobial effector mechanisms, such as degranulation, production of reactive oxygen species, and release of neutrophil extracellular... 
MAMMALIAN TARGET | NADPH OXIDASE | NETTING NEUTROPHILS | SIGNALING PATHWAYS | RESPIRATORY BURST | SYNOVIAL-FLUID | SUPEROXIDE-PRODUCTION | IN-VIVO | IMMUNOLOGY | RECEPTOR-III | CELL-DEATH | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - immunology | Macrophage-1 Antigen - immunology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Receptors, IgG - antagonists & inhibitors | Protein-Tyrosine Kinases - immunology | Lymphocyte Function-Associated Antigen-1 - immunology | Macrophage-1 Antigen - metabolism | Syk Kinase | CD11a Antigen - metabolism | Butadienes - pharmacology | Neutrophil Activation - immunology | GPI-Linked Proteins - immunology | Cell Degranulation | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | src-Family Kinases - antagonists & inhibitors | Autoimmune Diseases - immunology | Cells, Cultured | Neutrophils - immunology | Imidazoles - pharmacology | Inflammation - immunology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Pyrimidines - pharmacology | Receptors, IgG - immunology | src-Family Kinases - immunology | CD18 Antigens - metabolism | Mesalamine - pharmacology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Aminopyrine - pharmacology | Ascorbic Acid - pharmacology | Pyridines - pharmacology | Antigen-Antibody Complex - immunology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 403, pp. 48 - 58
Abstract Mesenchymal-type cancers after epithelial mesenchymal transition (EMT) were recently shown to acquire chemoresistance through expressing EMT specific... 
Hematology, Oncology and Palliative Medicine | BCL2 | Druggable target | Chemoradioresistance | Mesenchymal cancer cells | LAMTOR3 | ERK | SURVIVAL | METASTASIS | CELL INVASION | DEATH | TRANSITION | ONCOLOGY | RESISTANCE | INHIBITORS | PROMOTES | EXPRESSION | CONTRIBUTES | Up-Regulation | Adenocarcinoma - pathology | Diphenylamine - pharmacology | Adenocarcinoma of Lung | Humans | Radiation Tolerance | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Peptide Fragments - pharmacology | Chemoradiotherapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Diphenylamine - analogs & derivatives | Proto-Oncogene Proteins c-bcl-2 - metabolism | Molecular Mimicry | Transfection | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | RNA Interference | Adenocarcinoma - genetics | Benzamides - pharmacology | Signal Transduction - radiation effects | Lung Neoplasms - genetics | Proto-Oncogene Proteins - pharmacology | A549 Cells | Cell Survival - drug effects | MAP Kinase Kinase 1 - antagonists & inhibitors | Aniline Compounds - pharmacology | Lung Neoplasms - enzymology | Mitogen-Activated Protein Kinase 3 - genetics | Adenocarcinoma - enzymology | Etoposide - pharmacology | MAP Kinase Kinase 1 - metabolism | Lung Neoplasms - therapy | Sulfonamides - pharmacology | Piperazines - pharmacology | Adenocarcinoma - therapy | Mitogen-Activated Protein Kinase 3 - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - drug effects | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Mitogen-Activated Protein Kinases - metabolism | Medical research | Care and treatment | Lung cancer | Analysis | Stem cells | Medicine, Experimental | DNA binding proteins | Drug approval | Cancer | Adenocarcinoma | Drugs | Transcription factors | Immunoglobulins | Mesenchyme | Lung | Manufacturers | Chemoresistance | Extracellular signal-regulated kinase | MAP kinase | Breast cancer | Metastasis | Kinases | Gene expression | Drug resistance | Cancer therapies | Patients | Proteins | Cell growth | Pancreatic cancer | Trends | Apoptosis | Index Medicus
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 08/2002, Volume 174, Issue 2, pp. 233 - 246
Glucose-dependent insulinotropic polypeptide (GIP) acts as a glucose-dependent growth factor for beta-cells. Here we show that GIP and glucose also act... 
PATHWAYS | IGF-I | RECEPTOR TYROSINE KINASES | ACTIVATED PROTEIN-KINASE | PHOSPHATIDYLINOSITOL 3-KINASE | MAP KINASE | ENDOCRINOLOGY & METABOLISM | ELEMENT-BINDING PROTEIN | INS-1 CELLS | GROWTH-FACTOR | FACTOR-I | Apoptosis - drug effects | Calcium - metabolism | Humans | Maleimides - pharmacology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | MAP Kinase Kinase 1 | Isoquinolines - pharmacology | Deoxyglucose - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Flavonoids - pharmacology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Gastric Inhibitory Polypeptide - pharmacology | B-Lymphocytes - metabolism | Cell Line | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Arginase - genetics | Protein Kinase C - antagonists & inhibitors | Chelating Agents - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Sulfonamides - pharmacology | Egtazic Acid - pharmacology | MAP Kinase Signaling System - drug effects | Mitosis - drug effects | Androstadienes - pharmacology | Signal Transduction - drug effects | Glucokinase - antagonists & inhibitors | Plasmids | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Genistein - pharmacology | Glucose - metabolism | Alloxan - pharmacology | Benzylamines - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
CELL DEATH & DISEASE, ISSN 2041-4889, 12/2017, Volume 8, Issue 12, pp. 1 - 13
Multiple target inhibition has gained considerable interest in combating drug resistance in glioblastoma, however, understanding the molecular mechanisms of... 
CELL BIOLOGY | Phosphorylation | Hepatocyte growth factor | Transforming growth factor | Glioblastoma | Extracellular signal-regulated kinase | MAP kinase | AKT protein | Gene expression | Drug resistance | Kinases | 1-Phosphatidylinositol 3-kinase | c-Met protein | Signal transduction | Molecular modelling | Glioma cells | Stem cells | Growth factors | Index Medicus
Journal Article