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Molecular & Cellular Oncology, ISSN 2372-3556, 05/2019, Volume 6, Issue 3, pp. 1600350 - 1600350
In our recent publication, we describe a mechanism by which peroxisomes are protected from degradation by autophagy under basal conditions. Taking a page from... 
pexophagy | Mitophagy
Journal Article
MOVEMENT DISORDERS, ISSN 0885-3185, 09/2016, Volume 31, Issue 9, pp. 1340 - 1340
Journal Article
Genes and Development, ISSN 0890-9369, 2015, Volume 29, Issue 10, pp. 989 - 999
In this review, Durcan and Fon discuss how post-translational modifications are at the heart of how PARKIN and PINK1 function in mitochondrial quality control.... 
Ubiquitin | PARKIN | Phosphorylation | PINK1 | Mitophagy | Deubiquitination | mitophagy | deubiquitination | Review | phosphorylation | ubiquitin
Journal Article
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 04/2014, Volume 1841, Issue 4, pp. 525 - 534
Normal cellular function is dependent on a number of highly regulated homeostatic mechanisms, which act in concert to maintain conditions suitable for life.... 
GCN5L1 | Sirt3 | Acetylation | Mitophagy | Autophagy
Journal Article
Autophagy, ISSN 1554-8627, 2019, pp. 1 - 16
Mitophagy, which is a conserved cellular process for selectively removing damaged or unwanted mitochondria, is critical for mitochondrial quality control and... 
PGAM5 | PINK1-PRKN | Mitophagy | PHB2 | PARL
Journal Article
Autophagy, ISSN 1554-8627, 2019, pp. 1 - 19
Mitochondrial dynamics is highly implicated in a plethora of cellular processes including apoptosis and mitophagy. However, little is known about the scope and... 
BAX | mitophagy | MIEF1 | mitochondria | Apoptosis
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2019, Volume 42, Issue 3, pp. 401 - 410
Ridaifen (RID)-B is an analog derived from tamoxifen (TAM). TAM has an antitumor effect by acting as an antagonist to estrogen receptor (ER). However, TAM is... 
Journal Article
by Kim, YY and Um, JH and Yoon, JH and Kim, H and Lee, DY and Lee, YJ and Jee, HJ and Kim, YM and Jang, JS and Jang, YG and Chung, J and Park, HT and Finkel, T and Koh, H and Yun, J
FASEB JOURNAL, ISSN 0892-6638, 09/2019, Volume 33, Issue 9, pp. 9742 - 9751
Mitophagy has been implicated in mitochondrial quality control and in various human diseases. However, the study of in vivo mitophagy remains limited. We... 
PROTEIN | in vivo mitophagy | BIOCHEMISTRY & MOLECULAR BIOLOGY | quantitation of mitophagy | NEURODEGENERATION | PINK1/PARKIN MITOPHAGY | CELL BIOLOGY | FLY | PINK1 | Drosophila model | DISEASES | GENE | confocal microscopy | BIOLOGY | MITOCHONDRIAL DYSFUNCTION | MELANOGASTER | PROGRAMMED AUTOPHAGY | Index Medicus
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 08/2018, Volume 50, pp. 217 - 224
Hematotoxicity of benzene is derived mainly from its active metabolite, 1,4-Benzoquinone (1,4-BQ), which induces cell apoptosis and mitochondrial damage.... 
Benzene | Mitophagy | Autophagy | 1,4-Benzoquinone | Apoptosis
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 2019
Increased oxidative stress in patients with type 2 diabetes mellitus (T2DM) results in abnormalities in cell repair processes, such as mitophagy, which... 
T2DM | AMPK | metformin | mitophagy | PBMCs | Index Medicus
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2019, Volume 1865, Issue 7, pp. 1905 - 1914
Mitochondrial dysfunction contributes to heart failure induced mortality in approximately 80% of diabetic patients. Mitophagy degrades defective mitochondria... 
Sirt3 | Diabetic cardiomyopathy | Mitophagy | Mst1 | Parkin
Journal Article
Autophagy, ISSN 1554-8627, 06/2019, Volume 15, Issue 6, pp. 1112 - 1114
Our latest publication on the inhibition of Alzheimer disease (AD) through mitophagy consolidates the 'defective mitophagy hypothesis of AD etiology'. Dementia... 
memory | mitochondria | aging | Mitophagy | Alzheimer's disease
Journal Article
International Journal of Cardiology, ISSN 0167-5273, 07/2019
Journal Article
ACS Applied Materials and Interfaces, ISSN 1944-8244, 04/2017, Volume 9, Issue 15, pp. 13304 - 13314
Phosphorescent Ir(III) complexes are expected to be new multifunctional theranostic platforms that enable the integration of imaging capabilities and... 
phosphorescent emission | mitophagy | iridium(III) complex | theranostic | mitochondria | PHOTODYNAMIC ANTICANCER | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | MECHANISMS | DEATH | DEGRADATION | AGENTS | STRESS | AUTOPHAGY MITOPHAGY | PROBE | DERIVATIVES
Journal Article
BioScience Trends, ISSN 1881-7815, 2018
Mitochondrial damage is involved in the pathogenesis of osteoarthritis. Metformin, one of the most common prescriptions for patients with type 2 diabetes, can... 
mitophagy | Osteoarthritis | SIRT3
Journal Article
by Jee-hyun Um and and Jeanho Yun
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 6, p. 299
Mitophagy is a process of selective removal of damaged or unnecessary mitochondria using autophagic machinery. Mitophagy plays an essential role in maintaining... 
mitophagy activity | human diseases | Mitochondria dysfunctions | Mitophagy | human physiology
Journal Article
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