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JACC: Cardiovascular Interventions, ISSN 1936-8798, 07/2016, Volume 9, Issue 13, pp. 1361 - 1371
Objectives This study sought to evaluate the outcomes of the early experience of transcatheter mitral valve replacement (TMVR) with balloon-expandable valves... 
mitral annular calcification | mitral valve disease | transcatheter valve replacement | calcific mitral stenosis | mitral valve replacement | CARDIAC & CARDIOVASCULAR SYSTEMS | IMPLANTATION | PROSTHESIS | South America | Heart Valve Prosthesis Implantation - instrumentation | Postoperative Complications - etiology | Humans | Middle Aged | Calcinosis - diagnostic imaging | Male | Mitral Valve - surgery | Tomography, X-Ray Computed | Heart Valve Diseases - surgery | Cardiac Catheterization - mortality | Postoperative Complications - mortality | Prosthesis Design | Calcinosis - surgery | North America | Mitral Valve - physiopathology | Patient Selection | Time Factors | Cardiac Catheterization - methods | Aged, 80 and over | Heart Valve Diseases - mortality | Adult | Female | Registries | Retrospective Studies | Severity of Illness Index | Heart Valve Diseases - physiopathology | Risk Assessment | Europe | Heart Valve Prosthesis | Risk Factors | Calcinosis - mortality | Cardiac Catheterization - adverse effects | Heart Valve Prosthesis Implantation - methods | Heart Valve Prosthesis Implantation - mortality | Treatment Outcome | Cardiac Catheterization - instrumentation | Balloon Valvuloplasty | Mitral Valve - diagnostic imaging | Heart Valve Prosthesis Implantation - adverse effects | Aged | Calcinosis - physiopathology | Heart Valve Diseases - diagnostic imaging | Index Medicus
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 06/2013, Volume 6, Issue 6, pp. 598 - 605
Objectives The purpose of this study was to report the results of percutaneous valve-in-valve therapy using the Melody valve (Medtronic, Minneapolis,... 
percutaneous valve | valve-in-valve | bioprosthetic valve | tricuspid stenosis | mitral stenosis | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | CLINICAL-TRIAL | CONDUIT | DEGENERATED BIOPROSTHESES | TRANSCATHETER PULMONARY VALVE | REPLACEMENT | POSITION | DEFINITIONS | HIGH-RISK PATIENTS | LEFT-VENTRICULAR PUNCTURE | Heart Valve Prosthesis Implantation - instrumentation | Radiography, Interventional | Echocardiography, Transesophageal | Humans | Middle Aged | Bioprosthesis | Male | Mitral Valve - surgery | Prosthesis Design | Mitral Valve - physiopathology | Feasibility Studies | Prosthesis Failure | Tricuspid Valve - surgery | Tricuspid Valve Insufficiency - etiology | Tricuspid Valve Insufficiency - therapy | Aged, 80 and over | Adult | Female | Retrospective Studies | Child | Heart Valve Prosthesis | Cardiac Catheterization - adverse effects | Echocardiography, Three-Dimensional | Heart Valve Prosthesis Implantation - methods | Treatment Outcome | Tricuspid Valve - physiopathology | Mitral Valve Insufficiency - therapy | Cardiac Catheterization - instrumentation | Mitral Valve Insufficiency - diagnosis | Tricuspid Valve Insufficiency - diagnosis | Tricuspid Valve Insufficiency - physiopathology | Heart Valve Prosthesis Implantation - adverse effects | Adolescent | Aged | Hemodynamics | Mitral Valve Insufficiency - etiology | Mitral Valve Insufficiency - physiopathology | Index Medicus
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 11/2015, Volume 8, Issue 13, pp. 1735 - 1744
Journal Article
Circulation, ISSN 0009-7322, 02/2014, Volume 129, Issue 6, pp. 673 - 682
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 09/2014, Volume 7, Issue 9, pp. 1022 - 1032
Objectives The aim of this study was to determine the impact of the degree of residual aortic regurgitation (AR) and acuteness of presentation of AR after... 
transcatheter aortic valve implantation | transcatheter aortic valve replacement | paravalvular leak | aortic regurgitation | mitral regurgitation | acute aortic regurgitation | MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | STENOSIS | LONG-TERM OUTCOMES | TRANSESOPHAGEAL ECHOCARDIOGRAPHY | VALVULAR REGURGITATION | HIGH-RISK PATIENTS | IMPLANTATION | PROGRESSION | DOPPLER-ECHOCARDIOGRAPHY | REGISTRY | Heart Valve Prosthesis Implantation - instrumentation | Ventricular Function, Left | Humans | Male | Cardiac Catheterization - mortality | Prosthesis Design | Mitral Valve - physiopathology | Aortic Valve Stenosis - mortality | Time Factors | Ultrasonography | Aged, 80 and over | Female | Balloon Valvuloplasty - adverse effects | Severity of Illness Index | Aortic Valve - diagnostic imaging | Risk Assessment | Heart Valve Prosthesis | Risk Factors | Aortic Valve Stenosis - physiopathology | Kaplan-Meier Estimate | Proportional Hazards Models | Aortic Valve - physiopathology | Aortic Valve Insufficiency - physiopathology | Cardiac Catheterization - adverse effects | Heart Valve Prosthesis Implantation - methods | Heart Valve Prosthesis Implantation - mortality | Treatment Outcome | Aortic Valve Stenosis - diagnosis | Aortic Valve Stenosis - therapy | Aortic Valve Insufficiency - etiology | Cardiac Catheterization - instrumentation | Mitral Valve Insufficiency - diagnosis | Spain | Stroke Volume | Canada | Mitral Valve - diagnostic imaging | Heart Valve Prosthesis Implantation - adverse effects | Aged | Aortic Valve Insufficiency - mortality | Mitral Valve Insufficiency - physiopathology | Aortic Valve Insufficiency - diagnosis | Index Medicus
Journal Article
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2015, Volume 149, Issue 5, pp. 1270 - 1275
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2016, Volume 9, Issue 11, pp. 1161 - 1174
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2015, Volume 8, Issue 1, pp. 83 - 91
Abstract Objectives This study sought to evaluate the feasibility of transfemoral transcatheter heart valve (THV) implantation in failed mitral bioprostheses... 
Cardiovascular | valve-in-valve | mitral valve | valve-in-ring | transcatheter valve implantation | Valve-in-valve | Mitral valve | Transcatheter valve implantation | Valve-in-ring | transcatheter valve implantation | CARDIAC & CARDIOVASCULAR SYSTEMS | FAILURE | MELODY VALVE | REPLACEMENT | REPAIR | INTERVENTIONS | RECOMMENDATIONS | EXPERIENCE | ECHOCARDIOGRAPHY | DYSFUNCTION | Mitral Valve Annuloplasty - instrumentation | Heart Valve Prosthesis Implantation - instrumentation | Humans | Middle Aged | Bioprosthesis | Male | Mitral Valve - surgery | Cardiac Catheterization - mortality | Prosthesis Design | Mitral Valve Insufficiency - mortality | Mitral Valve - physiopathology | Feasibility Studies | Young Adult | Prosthesis Failure | Time Factors | Cardiac Catheterization - methods | Aged, 80 and over | Adult | Female | Femoral Artery | Heart Valve Prosthesis | Risk Factors | Kaplan-Meier Estimate | Cardiac Catheterization - adverse effects | Heart Valve Prosthesis Implantation - methods | Heart Valve Prosthesis Implantation - mortality | Treatment Outcome | Mitral Valve Annuloplasty - mortality | Mitral Valve Insufficiency - therapy | Cardiac Catheterization - instrumentation | Mitral Valve Insufficiency - diagnosis | Heart Valve Prosthesis Implantation - adverse effects | Adolescent | Aged | Mitral Valve Insufficiency - etiology | Mitral Valve Insufficiency - physiopathology | Mitral Valve Annuloplasty - adverse effects | Paris | Index Medicus
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 04/2017, Volume 10, Issue 8, pp. 798 - 809
Objectives This study sought to use a new catheter technique to split the anterior mitral valve leaflet (AML) and prevent iatrogenic left ventricular outflow... 
transcatheter mitral valve replacement | mitral valve | valvular heart disease | left ventricular outflow tract obstruction | structural heart disease | CARDIAC & CARDIOVASCULAR SYSTEMS | AORTIC-STENOSIS | IN-VALVE | RADIOFREQUENCY | PREDICTING LVOT OBSTRUCTION | ALCOHOL SEPTAL ABLATION | TRACT OBSTRUCTION | IMPLANTATION | ANNULAR CALCIFICATION | SAPIEN XT | ACCESS | Mitral Valve Annuloplasty - instrumentation | Heart Valve Prosthesis Implantation - instrumentation | Humans | Middle Aged | Male | Mitral Valve - surgery | Heart Valve Diseases - surgery | Iatrogenic Disease - prevention & control | Echocardiography, Doppler, Color | Prosthesis Design | Ventricular Outflow Obstruction - etiology | Mitral Valve - physiopathology | Protective Factors | Coronary Angiography - methods | Cardiac Catheterization - methods | Female | Ventricular Outflow Obstruction - diagnostic imaging | Mitral Valve Annuloplasty - methods | Heart Valve Diseases - physiopathology | Multidetector Computed Tomography | Heart Valve Prosthesis | Risk Factors | Cardiac Catheterization - adverse effects | Echocardiography, Three-Dimensional | Heart Valve Prosthesis Implantation - methods | Treatment Outcome | Cardiac Catheters | Ventricular Outflow Obstruction - prevention & control | Cardiac Catheterization - instrumentation | Michigan | Ventricular Outflow Obstruction - physiopathology | Mitral Valve - diagnostic imaging | Heart Valve Prosthesis Implantation - adverse effects | Aged | Georgia | Hemodynamics | Mitral Valve Annuloplasty - adverse effects | Heart Valve Diseases - diagnostic imaging | Index Medicus | left ventricular outglow tract obstruction
Journal Article
CARDIOVASCULAR RESEARCH, ISSN 0008-6363, 01/2017, Volume 113, Issue 1, pp. 40 - 51
Aims Myxomatous valve disease (MVD) is the most common aetiology of primary mitral regurgitation. Recent studies suggest that defects in heart valve... 
CARDIAC & CARDIOVASCULAR SYSTEMS | MOUSE | ECM remodelling | BETA-CATENIN | INTERSTITIAL-CELLS | Wnt/beta-catenin signalling | PATHOGENESIS | ORGANIZATION | Myxomatous valve disease | MARFAN-SYNDROME | Heart valve development | Axin2 | EXTRACELLULAR-MATRIX | DIFFERENTIATION | MITRAL-VALVE | UP-REGULATION | Axin Protein - deficiency | Cell Proliferation | Axin Protein - genetics | Aortic Valve - abnormalities | Extracellular Matrix - metabolism | Mitral Valve - metabolism | Mitral Valve - physiopathology | Mitral Valve Insufficiency - genetics | Morphogenesis | Heart Defects, Congenital - genetics | Bone Morphogenetic Proteins - metabolism | Gene Expression Regulation, Developmental | Fibrillin-1 - metabolism | Fibrillin-1 - genetics | Wnt Signaling Pathway | SOX9 Transcription Factor - metabolism | Aortic Valve Insufficiency - metabolism | Genetic Predisposition to Disease | Heart Defects, Congenital - pathology | Aortic Valve - physiopathology | Aortic Valve Insufficiency - physiopathology | Aortic Valve Insufficiency - pathology | Aggrecans - metabolism | Aortic Valve - metabolism | Marfan Syndrome - genetics | Mice, Knockout | Collagen - metabolism | Mitral Valve Insufficiency - pathology | Phenotype | Animals | Marfan Syndrome - metabolism | Marfan Syndrome - pathology | Heart Defects, Congenital - metabolism | Heart Defects, Congenital - physiopathology | Mutation | Extracellular Matrix - pathology | Mitral Valve Insufficiency - physiopathology | SOX9 Transcription Factor - genetics | Mitral Valve - abnormalities | Mitral Valve Insufficiency - metabolism | Index Medicus | β-catenin signalling | Original | Axin2 • Heart valve development • Myxomatous valve disease • ECM remodelling • Wnt
Journal Article
Circulation, ISSN 0009-7322, 07/2011, Volume 124, Issue 1, pp. 40 - 47
Journal Article
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 02/2016, Volume 87, Issue 3, pp. 478 - 487
BackgroundTranscatheter paravalvular leak closure (TPVLC) offers a viable alternative to reoperation but optimal technical strategy is still to be defined. We... 
percutaneous closure | occlude | aortic valve | mitral valve | valve prosthesis dysfunction | perivalvular leak | REPAIR | CARDIAC & CARDIOVASCULAR SYSTEMS | SURGICAL-CORRECTION | THROMBUS FORMATION | AORTIC-VALVE IMPLANTATION | RISK | Heart Valve Prosthesis Implantation - instrumentation | Echocardiography, Transesophageal | Prospective Studies | Patient Readmission | Humans | Middle Aged | Heart Failure - physiopathology | Bioprosthesis | Male | Heart Valve Diseases - surgery | Cardiac Catheterization - mortality | Echocardiography, Doppler, Color | Equipment Design | Mitral Valve Insufficiency - mortality | Vascular Closure Devices | Mitral Valve - physiopathology | Heart Failure - therapy | Prosthesis Failure | Time Factors | Peptide Fragments - blood | Female | Registries | Heart Failure - diagnostic imaging | Stents | Natriuretic Peptide, Brain - blood | Heart Failure - mortality | Hemolysis | Heart Valve Diseases - physiopathology | Aortic Valve Insufficiency - diagnostic imaging | Aortic Valve - diagnostic imaging | Heart Valve Prosthesis | Risk Factors | Aortic Valve - physiopathology | Aortic Valve Insufficiency - physiopathology | Cardiac Catheterization - adverse effects | Echocardiography, Three-Dimensional | Heart Valve Prosthesis Implantation - mortality | Treatment Outcome | Biomarkers - blood | Mitral Valve Insufficiency - therapy | Cardiac Catheterization - instrumentation | Mitral Valve - diagnostic imaging | Heart Valve Prosthesis Implantation - adverse effects | Aortic Valve Insufficiency - therapy | Aged | Mitral Valve Insufficiency - diagnostic imaging | Aortic Valve Insufficiency - mortality | Mitral Valve Insufficiency - physiopathology | Heart failure | Implants, Artificial | Prosthesis | Index Medicus
Journal Article
Heart, ISSN 1355-6037, 12/2017, Volume 103, Issue 24, pp. 1970 - 1976
ObjectivesTranscatheter aortic valve implantation (TAVI) has been implemented into the care of elderly patients suffering from severe symptomatic aortic... 
transcatheter valve interventions | endovascular procedures for aortic and vascular disease | REPLACEMENT | SURGERY | HIGH-RISK PATIENTS | CARDIAC & CARDIOVASCULAR SYSTEMS | LONG-TERM OUTCOMES | DISEASE | MITRAL REGURGITATION | PROSTHESIS | REGISTRY | Multivariate Analysis | Humans | Male | Aortic Valve - surgery | Prosthesis Design | Aortic Valve Stenosis - mortality | Time Factors | Aged, 80 and over | Mitral Valve Insufficiency - complications | Female | Registries | Aortic Valve Stenosis - surgery | Transcatheter Aortic Valve Replacement - adverse effects | Transcatheter Aortic Valve Replacement - instrumentation | Heart Valve Prosthesis | Risk Factors | Aortic Valve Stenosis - physiopathology | Kaplan-Meier Estimate | Proportional Hazards Models | Aortic Valve - physiopathology | Aortic Valve Insufficiency - physiopathology | Logistic Models | Treatment Outcome | Aortic Valve Insufficiency - etiology | Aortic Valve Stenosis - complications | Aged | Transcatheter Aortic Valve Replacement - mortality | Mitral Valve Insufficiency - physiopathology | Germany | Aged patients | Usage | Care and treatment | Aortic valve stenosis | Heart valve replacement | Heart | Prostheses | Working groups | Mortality | Values | Electrocardiography | Interdisciplinary aspects | Cardiology | Patients | Index Medicus | Abridged Index Medicus
Journal Article