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Cell (Cambridge), ISSN 0092-8674, 06/2010, Volume 141, Issue 6, pp. 1068 - 1079
Elucidation of molecular mechanisms that regulate synapse formation is required for the understanding of neural wiring, higher brain functions, and mental... 
PROTEINS | MOLNEURO | Proteins | Molneuro
Journal Article
Molecular cell, ISSN 1097-2765, 2006, Volume 22, Issue 6, pp. 795 - 806
The inositol 1,4,5-trisphosphate (IP 3) receptors (IP 3Rs) are IP 3-gated intracellular Ca 2+ channels. We previously identified an IP 3R binding protein,... 
MOLNEURO | SIGNALING
Journal Article
Cell (Cambridge), ISSN 0092-8674, 10/2009, Volume 139, Issue 2, pp. 380 - 392
Synapses are asymmetric cellular adhesions that are critical for nervous system development and function, but the mechanisms that induce their formation are... 
MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 06/2007, Volume 54, Issue 5, pp. 713 - 720
The apolipoprotein E (APOE) ε4 allele is the best established genetic risk factor for late-onset Alzheimer's disease (LOAD). We conducted genome-wide surveys... 
HUMDISEASE | MOLNEURO
Journal Article
Cell (Cambridge), ISSN 0092-8674, 04/2007, Volume 129, Issue 2, pp. 397 - 410
Spatial working memory (WM; i.e., “scratchpad” memory) is constantly updated to guide behavior based on representational knowledge of spatial position. It is... 
MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 06/2007, Volume 54, Issue 5, pp. 755 - 770
Ca2+ signaling plays a central role in activity-dependent regulation of dendritic arborization, but key molecular mechanisms downstream of calcium elevation... 
CELLBIO | DEVBIO | MOLNEURO
Journal Article
Developmental cell, ISSN 1534-5807, 2007, Volume 12, Issue 4, pp. 587 - 602
Neural activity regulates dendrite and synapse development, but the underlying molecular mechanisms are unclear. Ca 2+/calmodulin-dependent protein kinase II... 
PROTEINS | MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2007, Volume 53, Issue 3, pp. 439 - 452
Hallucinogens, including mescaline, psilocybin, and lysergic acid diethylamide (LSD), profoundly affect perception, cognition, and mood. All known drugs of... 
HUMDISEASE | MOLNEURO | SIGNALING
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 07/2007, Volume 55, Issue 1, pp. 25 - 36
Many biological functions depend critically upon fine details of tissue molecular architecture that have resisted exploration by existing imaging techniques.... 
CELLBIO | MOLNEURO | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Tomography | Physiological aspects | Proteins | Medical imaging | Architecture | Microscopy | Rodents | Arrays | Microscopes | Methods
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 12/2008, Volume 60, Issue 6, pp. 988 - 1009
β-site APP cleaving enzyme-1 (BACE1), the rate-limiting enzyme for β-amyloid (Aβ) production, is elevated in Alzheimer's disease (AD). Here, we show that... 
CELLBIO | HUMDISEASE | MOLNEURO | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 09/2007, Volume 55, Issue 6, pp. 859 - 873
NF-κB signaling has been implicated in neurodegenerative disease, epilepsy, and neuronal plasticity. However, the cellular and molecular activity of NF-κB... 
DEVBIO | MOLNEURO | SIGNALING
Journal Article
Cell (Cambridge), ISSN 0092-8674, 02/2010, Volume 140, Issue 4, pp. 567 - 578
The molecular mechanisms regulating the ubiquitin proteasome system (UPS) at synapses are poorly understood. We report that CaMKIIα—an abundant postsynaptic... 
CELLBIO | MOLNEURO | SIGNALING | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2007, Volume 55, Issue 6, pp. 942 - 957
Previously formed memories are susceptible to disruption immediately after recall due to a necessity to be reconsolidated after retrieval. Protein translation... 
SYSNEURO | DNA | MOLNEURO | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology
Journal Article