X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (563) 563
animals (334) 334
momordica charantia (222) 222
humans (209) 209
male (191) 191
rats (190) 190
momordica-charantia (188) 188
momordica charantia - chemistry (169) 169
biochemistry & molecular biology (163) 163
plant extracts - pharmacology (163) 163
mice (161) 161
diabetes (151) 151
pharmacology & pharmacy (129) 129
food science & technology (105) 105
chemistry, medicinal (96) 96
glucose (94) 94
bitter melon (90) 90
phytotherapy (89) 89
nutrition & dietetics (86) 86
insulin (83) 83
diabetes mellitus (80) 80
diabetes mellitus, experimental - drug therapy (80) 80
oxidative stress (78) 78
hypoglycemic agents - pharmacology (77) 77
integrative & complementary medicine (77) 77
plant sciences (76) 76
female (75) 75
proteins (74) 74
research (67) 67
seeds (65) 65
health aspects (64) 64
fruit (63) 63
hypoglycemic agents - therapeutic use (62) 62
metabolism (62) 62
analysis (61) 61
rats, wistar (61) 61
plant extracts - therapeutic use (60) 60
amino acid sequence (59) 59
in-vitro (59) 59
momordica - chemistry (58) 58
blood glucose - metabolism (57) 57
hypoglycemic activity (56) 56
plant extracts - chemistry (56) 56
chemistry, applied (54) 54
expression (54) 54
molecular sequence data (53) 53
seeds - chemistry (53) 53
plants (52) 52
dose-response relationship, drug (51) 51
insulin-resistance (51) 51
cell line, tumor (48) 48
extract (48) 48
obesity (46) 46
bitter gourd (45) 45
rodents (45) 45
enzymes (44) 44
antioxidants (43) 43
apoptosis (43) 43
insulin resistance (43) 43
plant proteins - metabolism (42) 42
research article (42) 42
biotechnology & applied microbiology (41) 41
care and treatment (41) 41
diabetes mellitus, experimental - blood (40) 40
fruit - chemistry (40) 40
medicinal plants (40) 40
mellitus (40) 40
diet (39) 39
fruits (39) 39
medicine (39) 39
physiological aspects (39) 39
streptozotocin (39) 39
blood glucose - drug effects (37) 37
cell biology (37) 37
hypoglycemic agents - chemistry (37) 37
liver - metabolism (37) 37
plant extracts - administration & dosage (37) 37
cancer (36) 36
momordica charantia - metabolism (36) 36
rats, sprague-dawley (36) 36
apoptosis - drug effects (35) 35
cucurbitaceae (35) 35
hyperglycemia (35) 35
liver (35) 35
plant proteins - chemistry (35) 35
glucose-tolerance (34) 34
gourd momordica-charantia (34) 34
herbal medicine (34) 34
momordica-cochinchinensis (34) 34
antioxidant (33) 33
medicine, herbal (33) 33
oncology (33) 33
cells (32) 32
gene expression (32) 32
inflammation (32) 32
medicine, botanic (32) 32
endocrinology & metabolism (31) 31
streptozocin (31) 31
body weight (30) 30
extracts (30) 30
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nutrients, ISSN 2072-6643, 12/2016, Volume 8, Issue 12, p. 805
We previously reported that bitter melon seed oil (BMSO) was an effective anti-steatosis and antiobesity agent. Since the major fatty acid alpha-eleostearic... 
Obesity | Bitter melon seed oil | α-eleostearic acid | Hepatic steatosis | PPARα | PPAR-ALPHA | M2 MACROPHAGES | PUNICIC ACID | CONJUGATED LINOLEIC-ACID | PPAR alpha | hepatic steatosis | OBESE MICE | WHITE ADIPOSE-TISSUE | BODY-FAT | NUTRITION & DIETETICS | GENE | ACYL-COA OXIDASE | alpha-eleostearic acid | ADAPTIVE RESPONSE | obesity | bitter melon seed oil | Tyrosine 3-Monooxygenase - metabolism | Acyl-CoA Oxidase - metabolism | Momordica charantia - chemistry | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Linoleic Acids, Conjugated - metabolism | Linolenic Acids - metabolism | Phytotherapy | Plant Oils - administration & dosage | Cyclic AMP-Dependent Protein Kinases - metabolism | Dyslipidemias - drug therapy | Adiposity - drug effects | Uncoupling Protein 1 - metabolism | Liver - metabolism | Mice, Inbred C57BL | PPAR alpha - genetics | Fatty Liver - drug therapy | Mice, Knockout | Triglycerides - metabolism | Oxidoreductases Acting on CH-CH Group Donors - metabolism | Animals | Signal Transduction - drug effects | PPAR alpha - physiology | Dyslipidemias - metabolism | Mice | PPAR alpha - metabolism | Plant Oils - chemistry | Adipose Tissue, White - drug effects | Protein kinase A | Adipose tissue | Body fat | Liver | Lipids | Kinases | Acyl-CoA oxidase | Tyrosine 3-monooxygenase | AMP-activated protein kinase | High fat diet | Proteins | Vitamin A | Signal transduction | Uncoupling protein 1 | Rodents | Lipid metabolism | Tyrosine | Enzymes | AMP | Hydroxylase | Cyclic AMP | Metabolism | Fatty acids | Steatosis | Oil | Fats and oils | Phagocytosis | Apoptosis | Index Medicus
Journal Article
by Kang, JM and Kim, N and Kim, B and Kim, JH and Lee, BY and Park, JH and Lee, MK and Lee, HS and Jang, IJ and Kim, JS and Jung, HC and Song, IS
DIGESTIVE DISEASES AND SCIENCES, ISSN 0163-2116, 12/2009, Volume 54, Issue 12, pp. 2549 - 2560
Cochinchina momordica seed extract (SK-MS10), which is composed of the major compounds momordica saponins, has been evaluated for its gastroprotective effects... 
Gastroprotection | AFFERENT NEURONS | MUCIN GENE-EXPRESSION | SENSITIVE SENSORY NEURONS | INCREASES | Cochinchina momordica | RAT GASTRIC-MUCOSA | Calcitonin gene-related peptide | Nitric oxide | EARLY VASCULAR INJURY | NITRIC-OXIDE | ETHANOL | GASTROENTEROLOGY & HEPATOLOGY | MUCUS GEL THICKNESS | CAPSAICIN | Tumor Necrosis Factor-alpha - metabolism | Seeds | Plant Extracts - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Stomach Ulcer - pathology | Gastric Mucosa - pathology | Male | RNA, Messenger - metabolism | Hexosamines - metabolism | Stomach Ulcer - etiology | Stomach Ulcer - enzymology | Group IV Phospholipases A2 - metabolism | Nitric Oxide Synthase Type I | Time Factors | Interleukin-1beta - metabolism | Gastric Mucosa - drug effects | Inflammation Mediators - metabolism | Leukotriene B4 - metabolism | Restraint, Physical | Calcitonin Gene-Related Peptide - blood | Sensory Receptor Cells - metabolism | Calcitonin Gene-Related Peptide - metabolism | Stomach Ulcer - prevention & control | Cytoprotection | Disease Models, Animal | Arachidonate 5-Lipoxygenase - metabolism | Ethanol | Down-Regulation | Gastric Mucosa - enzymology | Rats | Calcitonin Gene-Related Peptide - genetics | Rats, Sprague-Dawley | Momordica | Dinoprostone - metabolism | Gastrointestinal Agents - pharmacology | Animals | Sensory Receptor Cells - drug effects | Signal Transduction - drug effects | Cyclooxygenase 2 - metabolism | Mucin 5AC - metabolism | Nitric Oxide Synthase - metabolism | Nitric Oxide - metabolism | Mucin-6 - metabolism | Peroxidase - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 2017, Volume 17, Issue 1, pp. 319 - 319
Background: Hypercholesterolemia is a serious diseases associated with type-2 diabetes, atherosclerosis, cardiovascular disorders and liver diseases. Humans... 
Lipids | Carbohydrate | Gene expression | Hypercholesterolemia Karela | OXIDATIVE STRESS | HIGH-FAT DIET | PROLIFERATOR-ACTIVATED RECEPTORS | FED MICE | LIVER-DISEASE | HIGH-CHOLESTEROL DIET | INTEGRATIVE & COMPLEMENTARY MEDICINE | HYPOGLYCEMIC ACTIVITY | INSULIN-RESISTANCE | ADIPOCYTE DIFFERENTIATION | ADIPOSE-TISSUE | Fatty Acid Synthase, Type I - genetics | Hypercholesterolemia - diet therapy | Rats, Wistar | Humans | Liver - metabolism | Carbohydrate Metabolism | Rats | Lipid Metabolism | Male | Cholesterol - metabolism | Fatty Acid Synthase, Type I - metabolism | Momordica charantia - metabolism | Adipose Tissue - metabolism | Cholesterol 7-alpha-Hydroxylase - genetics | Animals | Anticholesteremic Agents - metabolism | Cholesterol 7-alpha-Hydroxylase - metabolism | Hypercholesterolemia - enzymology | Hypercholesterolemia - genetics | Hypercholesterolemia - metabolism | Carbohydrates | Care and treatment | Hypercholesterolemia | Research | Diagnosis | Bitter melon | Binding proteins | Adipose tissue | Liver | Disorders | Biochemistry | Adipocytes | Caspase-3 | Antioxidants | Deoxyribonucleic acid--DNA | Binding | Obesity | Enzymes | Liver diseases | Carbohydrate metabolism | Assessments | Metabolism | Fatty acids | Diseases | Carnitine | Studies | Diet | Arteriosclerosis | Bile | Access control | Drugs | Oxidative stress | Fas antigen | Transcription | Genes | Homeostasis | Superoxide dismutase | Tissues | Necrosis | Catalase | Rodents | Atherosclerosis | Coenzyme A | Glutathione | Food | Health | Diabetes mellitus | Caspase | Triglycerides | Pharmacology | Congestion | Cholesterol | Carnitine palmitoyltransferase | Insulin resistance | Diabetes | Index Medicus
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 12/2006, Volume 33, Issue 12, pp. 1150 - 1157
SUMMARY • Diabetes mellitus is a serious metabolic disorder with micro- and macrovascular complications that results in significant morbidity and mortality. •... 
Murraya koenigii | streptozotocin | Ocimum sanctum | Aegle marmelos | diabetes | antidiabetic activity | Mentha piperitae | Diabetes | Antidiabetic activity | Streptozotocin | PHYSIOLOGY | ADIPOCYTES | INSULIN BINDING | RENAL-FUNCTION | GLUCOSE-TRANSPORT | MELLITUS | EUGENIA-JAMBOLANA | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE | MOMORDICA-CHARANTIA | ENZYMES | LIVER | PHARMACOLOGY & PHARMACY | Diabetes Mellitus, Experimental - drug therapy | C-Peptide - blood | Rats, Wistar | Diabetes Mellitus, Experimental - enzymology | Glycogen Synthase - metabolism | Plant Extracts - pharmacology | Blood Urea Nitrogen | Glycated Hemoglobin A - metabolism | Body Weight - drug effects | Male | Insulin - blood | Liver Glycogen - metabolism | Diabetes Mellitus, Experimental - metabolism | Hypoglycemic Agents - therapeutic use | Carbohydrates | Glucose Tolerance Test | Plants, Medicinal - chemistry | Hemoglobins - metabolism | Rats | Creatinine - urine | Glycogen Phosphorylase - metabolism | India | Hypoglycemic Agents - isolation & purification | Animals | Blood Glucose - metabolism | Hemoglobins, metabolism | Plants, Medicinal, chemistry | Insulin, blood | Diabetes Mellitus, Experimental, enzymology | Hypoglycemic Agents, therapeutic use | Plant Extracts, pharmacology | Diabetes Mellitus, Experimental, drug therapy | Liver Glycogen, metabolism | Diabetes Mellitus, Experimental, metabolism | Creatinine, urine | Hemoglobin A, Glycosylated, metabolism | C-Peptide, blood | Blood Glucose, metabolism | Hypoglycemic Agents, isolation and purification | Body Weight, drug effects | Glycogen Phosphorylase, metabolism | Glycogen Synthase, metabolism | Plants | Index Medicus
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 07/2016, Volume 33, pp. 28 - 35
α-Eleostearic acid (α-ESA), or the -9, -11, -13 isomer of conjugated linolenic acid, is a special fatty acid present at high levels in bitter melon seed oil.... 
Sirtuin-1 | H4IIEC3 cells | PPARα | AMP-activated protein kinase | Nicotinamide phosphoribosyltransferase | α-Eleostearic acid | APOPTOSIS | ELEOSTEARIC-ACID | PUNICIC ACID | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PPAR alpha | LINOLENIC ACID | LIVER-DISEASE | PROTEIN-KINASE ACTIVATION | GOURD | NUTRITION & DIETETICS | OIL | alpha-Eleostearic acid | MICE | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Hypolipidemic Agents - metabolism | Momordica charantia - chemistry | Male | Hepatocytes - metabolism | Linoleic Acids, Conjugated - metabolism | Linolenic Acids - metabolism | NAD - chemistry | Non-alcoholic Fatty Liver Disease - blood | Seeds - chemistry | Tumor Cells, Cultured | Sirtuin 1 - chemistry | NAD - metabolism | Linolenic Acids - therapeutic use | Oxidation-Reduction | Signal Transduction | Mice, Inbred C57BL | Rats | Hypertriglyceridemia - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | AMP-Activated Protein Kinases - chemistry | Hypertriglyceridemia - blood | Gene Expression Regulation, Enzymologic | Hypertriglyceridemia - prevention & control | Animals | Non-alcoholic Fatty Liver Disease - prevention & control | PPAR alpha - agonists | Hypolipidemic Agents - therapeutic use | Enzyme Activation | Linoleic Acids, Conjugated - therapeutic use | PPAR alpha - metabolism | Dietary Supplements | Hepatocytes - enzymology | Index Medicus
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 11/2014, Volume 62, Issue 44, pp. 10717 - 10726
This study was designed to evaluate the effects and mechanism of tormentic acid (PTA) on diabetes and dyslipidemia in high-fat (HF)-fed mice. Feeding C57BL/6J... 
antihyperlipidemia | glucose transporter 4 | tormentic acid | AMP-activated protein kinase phosphorylation | antidiabetes | TRANSLOCATION | RAT | FOOD SCIENCE & TECHNOLOGY | FED MICE | LIVER-DISEASE | MOMORDICA-CHARANTIA | OBESITY | INSULIN-RESISTANCE | ENHANCEMENT | AGRICULTURE, MULTIDISCIPLINARY | ROSIGLITAZONE | CHEMISTRY, APPLIED | HEPATIC GLUCOSE-PRODUCTION | AMP-Activated Protein Kinases - metabolism | Hyperlipidemias - genetics | Liver - enzymology | Glucose Transporter Type 4 - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Diet, High-Fat - adverse effects | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Eriobotrya - growth & development | Hyperlipidemias - enzymology | Plant Extracts - administration & dosage | Eriobotrya - chemistry | Phosphorylation - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Muscle, Skeletal - enzymology | Glucose Transporter Type 4 - genetics | Hyperlipidemias - metabolism | Hyperlipidemias - drug therapy | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Diabetes Mellitus, Type 2 - enzymology | Triglycerides - metabolism | Insulin - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Mice | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Triterpenes - administration & dosage | AMP-Activated Protein Kinases - genetics | Index Medicus
Journal Article
Journal Article
Journal Article
Chemistry & Biology, ISSN 1074-5521, 03/2008, Volume 15, Issue 3, pp. 263 - 273
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 04/2017, Volume 97, pp. 544 - 551
Journal Article
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 07/2018, Volume 23, Issue 8, p. 1894
Obesity and nonalcoholic fatty liver disease (NAFLD) are highly prevalent and cause numerous metabolic diseases. However, drugs for the prevention and... 
AMPK | nonalcoholic fatty liver disease | mogrosides | Siraitia grosvenorii | p62 | obesity | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, MULTIDISCIPLINARY | SUGAR | Non-alcoholic Fatty Liver Disease - pathology | AMP-Activated Protein Kinases - metabolism | Liver - pathology | Reactive Oxygen Species - metabolism | Triterpenes - pharmacology | Obesity - drug therapy | Humans | Body Weight - drug effects | Diet, High-Fat - adverse effects | Non-alcoholic Fatty Liver Disease - etiology | Anticholesteremic Agents - chemistry | Male | Saponins - chemistry | Adipose Tissue - metabolism | Sequestosome-1 Protein - agonists | Triterpenes - chemistry | Liver - drug effects | Obesity - etiology | Sequestosome-1 Protein - metabolism | Momordica - chemistry | Liver - metabolism | Adipose Tissue - pathology | Gene Expression Regulation | THP-1 Cells | Non-alcoholic Fatty Liver Disease - metabolism | Anticholesteremic Agents - isolation & purification | Anti-Obesity Agents - isolation & purification | Hep G2 Cells | Non-alcoholic Fatty Liver Disease - drug therapy | Obesity - metabolism | Obesity - pathology | Sequestosome-1 Protein - genetics | Anti-Obesity Agents - chemistry | Organ Size - drug effects | Reactive Oxygen Species - antagonists & inhibitors | Animals | Saponins - isolation & purification | Triterpenes - isolation & purification | Mice | Adipose Tissue - drug effects | Anti-Obesity Agents - pharmacology | AMP-Activated Protein Kinases - genetics | Anticholesteremic Agents - pharmacology | Saponins - pharmacology | Obesity | Saponins | Phosphorylation | Reactive oxygen species | Liver diseases | Fat metabolism | AMP | Liver | Purity | Metabolism | Kinases | AMP-activated protein kinase | Weight | High fat diet | Proteins | Fatty liver | Molecular modelling | Diet | Metabolic disorders | Index Medicus
Journal Article