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1. Full Text Neurochemical binding profiles of novel indole and benzofuran MDMA analogues
by Shimshoni, Jakob A and Shimshoni, Jakob A and Winkler, Ilan and Winkler, Ilan and Golan, Ezekiel and Golan, Ezekiel and Nutt, David and Nutt, David
Naunyn-Schmiedeberg's archives of pharmacology, ISSN 0028-1298, 1/2017, Volume 390, Issue 1, pp. 15 - 24
Neurosciences | Biomedicine | Monoamine receptors | Neurochemical profile | MDMA analogues | Monoamine transporters | Pharmacology/Toxicology | 3,4-Methylenedioxy- N -methylamphetamine (MDMA) | 3,4-Methylenedioxy-N-methylamphetamine (MDMA) | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Tyrosine 3-Monooxygenase - metabolism | Vesicular Monoamine Transport Proteins - metabolism | Receptors, Serotonin, 5-HT2 - chemistry | Stress Disorders, Post-Traumatic - metabolism | Humans | Neurotransmitter Uptake Inhibitors - pharmacology | Benzofurans - pharmacology | Serotonin 5-HT2 Receptor Agonists - pharmacology | Receptors, Serotonin, 5-HT2 - drug effects | Structure-Activity Relationship | Receptors, Serotonin, 5-HT2 - metabolism | Neurotransmitter Uptake Inhibitors - metabolism | Benzofurans - chemistry | Catechol O-Methyltransferase - metabolism | Monoamine Oxidase - chemistry | Indoles - metabolism | Tyrosine 3-Monooxygenase - chemistry | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Stress Disorders, Post-Traumatic - drug therapy | Indoles - pharmacology | N-Methyl-3,4-methylenedioxyamphetamine - chemistry | Radioligand Assay | Serotonin 5-HT2 Receptor Agonists - metabolism | Binding Sites | Monoamine Oxidase Inhibitors - pharmacology | Vesicular Monoamine Transport Proteins - chemistry | Vesicular Monoamine Transport Proteins - antagonists & inhibitors | Serotonin 5-HT2 Receptor Agonists - chemistry | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Neurotransmitter Uptake Inhibitors - chemistry | Monoamine Oxidase Inhibitors - metabolism | Protein Binding | Protein Conformation | Monoamine Oxidase Inhibitors - chemistry | Catechol O-Methyltransferase - chemistry | Indoles - chemistry | Benzofurans - metabolism | Monoamine Oxidase - metabolism | Monoamine oxidase | Batteries | Methamphetamine | Ecstasy (Drug) | Resveratrol | Post-traumatic stress disorder | Index Medicus
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2. Full Text Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation
by Wu, Ming-Yu and Esteban, Gerard and Brogi, Simone and Shionoya, Masahi and Wang, Li and Campiani, Giuseppe and Unzeta, Mercedes and Inokuchi, Tsutomu and Butini, Stefania and Marco-Contelles, Jose
European journal of medicinal chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 864 - 879
Human acetylcholinesterase | MAO-A | Molecular modeling | Human butyrylcholinesterase | Metal chelating properties | ADME+T properties | Antioxidant properties | MAO-B | Alzheimer's disease | Molecular docking | Antioxidants - chemistry | Antioxidants - metabolism | Humans | Structure-Activity Relationship | Monoamine Oxidase Inhibitors - chemical synthesis | Monoamine Oxidase - chemistry | Piperidines - pharmacology | Drug Design | Indans - chemistry | Monoamine Oxidase Inhibitors - pharmacology | Piperidines - chemistry | Chemistry Techniques, Synthetic | Piperidines - metabolism | Chelating Agents - chemistry | Indans - metabolism | Acetylcholinesterase - chemistry | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Chelating Agents - pharmacology | Piperidines - chemical synthesis | Monoamine Oxidase Inhibitors - metabolism | Indans - chemical synthesis | Protein Conformation | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Chelating Agents - chemical synthesis | Chelating Agents - metabolism | Acetylcholinesterase - metabolism | Indans - pharmacology | Monoamine Oxidase - metabolism | Antioxidants | Enzymes | Monoamine oxidase | Analysis | Models | Drug discovery | Target marketing | Index Medicus
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3. Full Text Monoamine oxidase inhibitory activity of methoxy-substituted chalcones
by Mathew, Bijo and Mathew, Githa Elizabeth and Ucar, Gulberk and Joy, Monu and Nafna, E.K and Lohidakshan, Krishnakumar K and Suresh, Jerad
International journal of biological macromolecules, ISSN 0141-8130, 11/2017, Volume 104, Issue Pt A, pp. 1321 - 1329
Reversibility | Monoamine oxidase | Substrate cavity | Entrance cavity | Chalcone | Molecular docking | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Polymer Science | Science & Technology | Chalcones - chemistry | Monoamine Oxidase Inhibitors - pharmacology | Catalytic Domain | Humans | Blood-Brain Barrier - metabolism | Hep G2 Cells | Chalcones - metabolism | Monoamine Oxidase - chemistry | Monoamine Oxidase Inhibitors - toxicity | Chalcones - toxicity | Chalcones - pharmacology | Drug Design | Monoamine Oxidase Inhibitors - metabolism | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Monoamine Oxidase - metabolism | Drugstores | Butylene | Pharmacy | Index Medicus
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4. Full Text New Frontiers in Selective Human MAO-B Inhibitors
by Carradori, Simone and Silvestri, Romano
Journal of medicinal chemistry, ISSN 0022-2623, 09/2015, Volume 58, Issue 17, pp. 6717 - 6732
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Monoamine Oxidase Inhibitors - pharmacology | Isoenzymes - genetics | Humans | Isoenzymes - chemistry | Structure-Activity Relationship | Monoamine Oxidase - genetics | Polymorphism, Genetic | Monoamine Oxidase - chemistry | Isoenzymes - metabolism | Protein Conformation | Monoamine Oxidase Inhibitors - chemistry | Isoenzymes - antagonists & inhibitors | Monoamine Oxidase - metabolism | Index Medicus
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5. Inhibitor design for monoamine oxidases
by Ramsay, Rona R
Current pharmaceutical design, ISSN 1381-6128, 2013, Volume 19, Issue 14, pp. 2529 - 2539
Steady-state kinetic analysis | Redox state | Monoamine oxidase | Structure-based drug design | Neurotransmitter levels | Covalently-bound FAD | Anti-depressant | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Monoamine Oxidase Inhibitors - therapeutic use | Monoamine Oxidase Inhibitors - pharmacology | Humans | Models, Molecular | Substrate Specificity | Monoamine Oxidase - genetics | Monoamine Oxidase - chemistry | Drug Design | Molecular Structure | Monoamine Oxidase Inhibitors - chemistry | Kinetics | Binding Sites | Monoamine Oxidase - metabolism
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6. Full Text Potent inhibitions of monoamine oxidase A and B by acacetin and its 7-O-(6-O-malonylglucoside) derivative from Agastache rugosa
by Lee, Hyun Woo and Ryu, Hyung Won and Baek, Seung Cheol and Kang, Myung-Gyun and Park, Daeui and Han, Hyoung-Yun and An, Ju Hyeon and Oh, Sei-Ryang and Kim, Hoon
International journal of biological macromolecules, ISSN 0141-8130, 11/2017, Volume 104, Issue Pt A, pp. 547 - 553
Acacetin 7-O-(6-O-malonylglucoside) | Acacetin | Monoamine oxidase inhibition | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Polymer Science | Science & Technology | Monoamine Oxidase Inhibitors - pharmacology | Agastache - chemistry | Flavones - metabolism | Humans | Structure-Activity Relationship | Flavones - chemistry | Monoamine Oxidase - chemistry | Monoamine Oxidase Inhibitors - metabolism | Glucosides - chemistry | Inhibitory Concentration 50 | Protein Conformation | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Flavones - pharmacology | Monoamine Oxidase - metabolism | Monoamine oxidase | Research institutes | Index Medicus
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7. Full Text The therapeutic potential of monoamine oxidase inhibitors
by Tipton, Keith F and Edmondson, Dale and Youdim, Moussa B. H
Nature reviews. Neuroscience, ISSN 1471-003X, 04/2006, Volume 7, Issue 4, pp. 295 - 309
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Behavioral psychophysiology | Psychology. Psychoanalysis. Psychiatry | Psychology. Psychophysiology | Electrophysiology | Biological and medical sciences | General aspects. Models. Methods | Monoamine Oxidase Inhibitors - therapeutic use | Monoamine Oxidase Inhibitors - pharmacology | Humans | Structure-Activity Relationship | Neurodegenerative Diseases - drug therapy | Monoamine Oxidase - chemistry | Animals | Signal Transduction - drug effects | Models, Biological | Monoamine Oxidase Inhibitors - metabolism | Signal Transduction - physiology | Monoamine Oxidase Inhibitors - chemistry | Cerebral Cortex - drug effects | Monoamine Oxidase - metabolism | Neurodegenerative Diseases - classification | Index Medicus
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