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IUBMB Life, ISSN 1521-6543, 01/2012, Volume 64, Issue 1, pp. 1 - 9
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 2/2016, Volume 94, Issue 2, pp. 155 - 171
Journal Article
Journal Article
Journal Article
by Rusu, Victor and Hoch, Eitan and Mercader, Josep M and Tenen, Danielle E and Gymrek, Melissa and Hartigan, Christina R and DeRan, Michael and von Grotthuss, Marcin and Fontanillas, Pierre and Spooner, Alexandra and Guzman, Gaelen and Deik, Amy A and Pierce, Kerry A and Dennis, Courtney and Clish, Clary B and Carr, Steven A and Wagner, Bridget K and Schenone, Monica and Ng, Maggie C.Y and Chen, Brian H and Chen, Guanjie and Chen, Wei-Min and Chen, Y-D Ida and Shriner, Daniel and Li, Jiang and Guo, Xiuqing and Liu, Jiankang and Liu, Yongmei and Liu, Simin and Bielinski, Suzette J and Yanek, Lisa R and Nalls, Michael A and Comeau, Mary E and Rasmussen-Torvik, Laura J and Jensen, Richard A and Evans, Michele K and Evans, Daniel S and Sun, Yan V and An, Ping and Patel, Sanjay R and Lu, Yingchang and Long, Jirong and Armstrong, Loren L and Wagenknecht, Lynne and Yang, Lingyao and Snively, Beverly M and Palmer, Nicholette D and Mudgal, Poorva and Langefeld, Carl D and Keene, Keith L and Freedman, Barry I and Mychaleckyj, Josyf C and Nayak, Uma and Raffel, Leslie J and Goodarzi, Mark O and Taylor, Herman A and Correa, Adolfo and Sims, Mario and Couper, David and Pankow, James S and Boerwinkle, Eric and Adeyemo, Adebowale and Doumatey, Ayo and Mathias, Rasika A and Vaidya, Dhananjay and Singleton, Andrew B and Zonderman, Alan B and Igo, Robert P and Sedor, John R and Kabagambe, Edmond K and Siscovick, David S and McKnight, Barbara and Rice, Kenneth and Hsueh, Wen-Chi and Zhao, Wei and Bielak, Lawrence F and Kraja, Aldi and Province, Michael A and Bottinger, Erwin P and Gottesman, Omri and Cai, Qiuyin and Zheng, Wei and Blot, William J and Lowe, William L and Pacheco, Jennifer A and Crawford, Dana C and Grundberg, Elin and Rich, Stephen S and Hayes, M. Geoffrey and Shu, Xiao-Ou and Loos, Ruth J.F and Borecki, Ingrid B and Peyser, Patricia A and Cummings, Steven R and Psaty, Bruce M and Fornage, Myriam and Iyengar, Sudha K and Becker, Diane M and Kao, W.H. Linda and Wilson, James G and ... and MEDIA Consortium and SIGMA T2D Consortium
Cell, ISSN 0092-8674, 06/2017, Volume 170, Issue 1, pp. 199 - 212.e20
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2016, Volume 892, pp. 229 - 251
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2015, Volume 466, Issue 1, pp. 177 - 188
The proton-linked monocarboxylate transporters (MCTs) are required for lactic acid transport into and out of all mammalian cells. Thus, they play an essential... 
Xenopus oocytes | Lactate transport | Molecular modelling | Molecular dynamics (MD) simulations | Monocarboxylate transporter 1 (MCT1) | Monocarboxylate transporter 4 (MCT4) | TRANSMEMBRANE HELICES | molecular modelling | monocarboxylate transporter 4 (MCT4) | BIOCHEMISTRY & MOLECULAR BIOLOGY | PYRUVATE TRANSPORT | lactate transport | molecular dynamics (MD) simulations | MONOCARBOXYLATE | ANCILLARY PROTEIN | SKELETAL-MUSCLE | INHIBITION | monocarboxylate transporter 1 (MCT1) | HUMAN-ERYTHROCYTES | ASCITES TUMOR-CELLS | LACTIC-ACID EFFLUX | Humans | Oocytes - cytology | Monocarboxylic Acid Transporters - antagonists & inhibitors | Monocarboxylic Acid Transporters - metabolism | Biological Transport | Symporters - antagonists & inhibitors | Muscle Proteins - metabolism | Female | Binding Sites | Uracil - chemistry | Monocarboxylic Acid Transporters - chemistry | Recombinant Proteins - metabolism | Gene Expression | Lactic Acid - chemistry | Mutagenesis, Site-Directed | Oocytes - metabolism | Lactic Acid - metabolism | Xenopus laevis | Rats | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Symporters - chemistry | Amino Acids | Symporters - metabolism | Muscle Proteins - genetics | Animals | Symporters - genetics | Protein Binding | Mice | Molecular Docking Simulation | Muscle Proteins - chemistry | Monocarboxylic Acid Transporters - genetics | Thiophenes - chemistry | Amino Acid Substitution | Uracil - analogs & derivatives | Index Medicus | OPLS–AA, optimized potentials for liquid simulations–all atoms | WT, wild-type | MCT, monocarboxylate transporter | CHC, α-cyano-4-hydroxycinnamate | POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | DIDS, 4,4′-diisothiocyano-2,2′-stilbenedisulfonic acid | MD, molecular dynamics | SPC, simple point charge | TM, transmembrane helix | SDM, site-directed mutagenesis
Journal Article
Journal Article