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Human antibodies, ISSN 1093-2607, 1997
Journal
Immunopharmacology and immunotoxicology, ISSN 0892-3973, 1987
Journal
Nature (London), ISSN 1476-4687, 2014, Volume 515, Issue 7525, pp. 138 - 142
The isolation of human monoclonal antibodies is providing important insights into the specificities that underlie broad neutralization of HIV-1 (reviewed in ref. 1... 
B-CELLS | SPECIFICITIES | MULTIDISCIPLINARY SCIENCES | SERA | IMMUNODEFICIENCY-VIRUS TYPE-1 | ENV TRIMERS | VULNERABILITY | GP120 | HUMAN MONOCLONAL-ANTIBODIES | CLEAVAGE | DEPENDENT EPITOPE | Immunoglobulin Fab Fragments - ultrastructure | Antibody Specificity | Epitope Mapping | HIV Envelope Protein gp41 - immunology | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Leukocytes, Mononuclear | HIV Envelope Protein gp41 - chemistry | Virus Internalization - drug effects | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | Receptors, CCR5 - metabolism | HIV Antibodies - immunology | Conserved Sequence | Inhibitory Concentration 50 | HIV Envelope Protein gp120 - chemistry | HIV Antibodies - pharmacology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Cell Line | Immunoglobulin Fab Fragments - genetics | HIV-1 - drug effects | Antibodies, Monoclonal - pharmacology | Models, Molecular | Antibodies, Neutralizing - pharmacology | Antibody Affinity | Antibodies, Neutralizing - genetics | HIV Antibodies - chemistry | AIDS Vaccines - chemistry | Antibodies, Monoclonal - genetics | HIV-1 - immunology | Antibodies, Neutralizing - chemistry | Immunoglobulin Fab Fragments - chemistry | Cell Membrane - virology | Epitopes - chemistry | HIV Antibodies - genetics | Immunoglobulin Fab Fragments - immunology | CD4 Antigens - metabolism | Viral antibodies | Care and treatment | Antibodies | Physiological aspects | Genetic aspects | Research | HIV infection | Antigenic determinants | Amino acids | Mutation | Vaccines | Human immunodeficiency virus--HIV | Binding sites | Index Medicus
Journal Article
2005, 1. Aufl., ISBN 3527306889, 618
Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated... 
Antibodies, Catalytic | Monoclonal antibodies | Antibody-enzyme conjugates | Clinical & internal medicine
eBook
Nature (London), ISSN 1476-4687, 2016, Volume 533, Issue 7601, pp. 105 - 109
...) infection, little progress has been made in generating an effective HIV-1 vaccine. Although passive transfer of anti-HIV-1 broadly neutralizing antibodies can protect... 
SIMIAN/HUMAN IMMUNODEFICIENCY VIRUS | POTENT | TRANSMISSION | HIV-1/SIV CHIMERIC VIRUS | BROADLY NEUTRALIZING ANTIBODY | MULTIDISCIPLINARY SCIENCES | IMPROVES PROTECTION | PASSIVE TRANSFER | MACAQUES | INFECTION | MONOCLONAL-ANTIBODIES | HIV Antibodies - blood | Antibodies, Neutralizing - administration & dosage | HIV Infections - prevention & control | AIDS Vaccines - immunology | Macaca mulatta - immunology | Half-Life | Male | Antibodies, Monoclonal - blood | HIV Infections - immunology | Macaca mulatta - virology | Antibodies, Neutralizing - immunology | Immunoglobulin Fc Fragments - immunology | HIV Antibodies - immunology | Time Factors | Female | HIV Infections - transmission | Antibodies, Monoclonal - immunology | Simian Immunodeficiency Virus - immunology | Protein Structure, Tertiary | SAIDS Vaccines - administration & dosage | Immunoglobulin Fc Fragments - chemistry | Antibodies, Neutralizing - genetics | Mutation - genetics | Simian Acquired Immunodeficiency Syndrome - blood | HIV Antibodies - administration & dosage | Simian Acquired Immunodeficiency Syndrome - prevention & control | Antibodies, Monoclonal - genetics | Animals | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Antibodies, Monoclonal - administration & dosage | HIV Antibodies - genetics | AIDS Vaccines - administration & dosage | Immunoglobulin Fc Fragments - genetics | Antibodies, Neutralizing - blood | Prevention | Viral antibodies | Antibodies | Dosage and administration | HIV infection | Patient outcomes | Monoclonal antibodies | Immunoglobulins | Immunization | Vaccines | Human immunodeficiency virus--HIV | Viral infections
Journal Article
Nature, ISSN 0028-0836, 08/2014, Volume 514, Issue 7524, pp. 642 - 645
To protect against human immunodeficiency virus (HIV-1) infection, broadly neutralizing antibodies (bnAbs... 
HALF-LIFE | CHALLENGE | IMMUNITY | TRANSPORT | NEUTRALIZING ANTIBODIES | HUMAN IGG1 | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MONOCLONAL-ANTIBODIES | HIV-1 VACCINE | HIV Antibodies - blood | Antibodies, Neutralizing - analysis | HIV Infections - prevention & control | Immunity, Mucosal - immunology | Antibody-Dependent Cell Cytotoxicity - immunology | Half-Life | Administration, Rectal | Antibody Affinity - immunology | Male | HIV - immunology | Macaca mulatta | Antibodies, Viral - blood | Receptors, IgG - metabolism | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | HIV Envelope Protein gp160 - chemistry | Antibodies, Viral - analysis | HIV - chemistry | Intestinal Mucosa - immunology | Female | Transcytosis | Simian Immunodeficiency Virus - immunology | HIV Antibodies - analysis | Mutagenesis, Site-Directed | Histocompatibility Antigens Class I - immunology | Antibody Affinity - genetics | Antibodies, Neutralizing - genetics | Binding Sites - genetics | Receptors, IgG - immunology | Rectum - immunology | Simian Acquired Immunodeficiency Syndrome - prevention & control | Animals | Receptors, Fc - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Immunization, Passive | Antibodies, Viral - immunology | HIV Envelope Protein gp160 - immunology | Mice | HIV Antibodies - genetics | Antibodies, Neutralizing - blood | Antibodies, Viral - genetics | CD4 Antigens - metabolism | Viral antibodies | Infection | Prevention | Fc receptors | Protein research | Antibodies | Primates | Research | Simian immunodeficiency virus | Health aspects | T cell receptors | Physiology | Mutation | Human immunodeficiency virus--HIV | Viral infections | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 561, Issue 7724, pp. 479 - 484
.... Here we report on a phase 1b clinical trial in which a combination of 3BNC117 and 10-1074, two potent monoclonal anti-HIV-1 broadly neutralizing antibodies that target independent sites on the HIV-1... 
SHIV INFECTION | PRIMARY HIV-INFECTION | RESERVOIR | DURABLE CONTROL | BROADLY NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | PASSIVE TRANSFER | IN-VIVO | TREATMENT INTERRUPTION | T-CELLS | HUMANIZED MICE | Antibodies, Neutralizing - administration & dosage | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Drug Resistance, Viral | Antibodies, Monoclonal - therapeutic use | Male | Phylogeny | Anti-HIV Agents - administration & dosage | Young Adult | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - adverse effects | HIV Antibodies - immunology | HIV-1 - isolation & purification | Antibodies, Neutralizing - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Antibodies, Neutralizing - adverse effects | Female | HIV Antibodies - therapeutic use | Historically Controlled Study | Antibodies, Monoclonal - immunology | Carrier State - immunology | HIV Infections - virology | Viremia - drug therapy | HIV Antibodies - administration & dosage | Carrier State - virology | HIV-1 - immunology | Viremia - virology | Antibodies, Monoclonal - administration & dosage | Viremia - prevention & control | Adolescent | Carrier State - drug therapy | HIV Infections - drug therapy | Viremia - immunology | Aged | HIV Envelope Protein gp160 - immunology | Infusions, Intravenous | Binding Sites, Antibody | Virus Activation - immunology | Virus Latency - immunology | Anti-HIV Agents - immunology | Drug Combinations | Physiological aspects | HIV patients | Care and treatment | Drug therapy, Combination | HIV antibodies | Antiretroviral drugs | Therapy | Antiviral agents | Interruption | Immunoglobulins | Viremia | Clinical trials | Viruses | Infections | Genomes | Antiretroviral therapy | Antiretroviral agents | Lymphocytes | Human immunodeficiency virus--HIV | Monoclonal antibodies | Drug therapy | Bioinformatics | Binding sites
Journal Article
Nature immunology, ISSN 1529-2916, 2016, Volume 17, Issue 9, pp. 1102 - 1108
.... Here we investigated the serological cross-reaction between the two viruses. Plasma immune to DENV showed substantial cross-reaction to ZIKV and was able to drive antibody-dependent enhancement (ADE) of ZIKV infection... 
NEUTRALIZING ANTIBODIES | IMMUNOLOGY | CHIKUNGUNYA VIRUS | OUTBREAK | BRAZIL | BRAIN | Immunodominant Epitopes - immunology | Antibody-Dependent Enhancement | Epitope Mapping | Humans | Child, Preschool | Male | Antibodies, Viral - blood | Microcephaly - epidemiology | Antibodies, Monoclonal - blood | Antibodies, Neutralizing - immunology | South America - epidemiology | Immunodominant Epitopes - metabolism | Guillain-Barre Syndrome - epidemiology | Viral Envelope Proteins - metabolism | Female | Dengue - immunology | Child | Antibodies, Monoclonal - immunology | Zika Virus - physiology | Cells, Cultured | Dengue - epidemiology | Cross Reactions | Zika Virus Infection - epidemiology | Virus Replication | Adolescent | Protein Binding | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Dengue Virus - physiology | Viral Envelope Proteins - immunology | Antibodies, Neutralizing - blood | Medical research | Immune response | Comorbidity | Dengue | Medicine, Experimental | Development and progression | Research | Observations | South America | Populations and Evolution | Viral Envelope Proteins | Zika Virus Infection | Microcephaly | Guillain-Barre Syndrome | Life Sciences | Computer Science | Genetics | Bioinformatics | Antibodies, Neutralizing | Parasitology | Quantitative Methods | Zika Virus | Antibodies, Monoclonal | Antibodies, Viral | Dengue Virus | Virology | Microbiology and Parasitology | Santé publique et épidémiologie | Immunodominant Epitopes | Human genetics
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2011, Volume 334, Issue 6059, pp. 1097 - 1103
The HIV envelope (Env) protein gpl20 is protected from antibody recognition by a dense glycan shield... 
Polysaccharides | HIV | Neutralizing antibodies | RESEARCH ARTICLES | Antibodies | Viruses | Trimers | Epitopes | Grants | Binding sites | Crystal structure | PANEL | TRIMERS | MULTIDISCIPLINARY SCIENCES | IMMUNOGENS | ENVELOPE GLYCOPROTEIN COMPLEX | GP120 | HUMAN-IMMUNODEFICIENCY-VIRUS | MONOCLONAL-ANTIBODIES | TYPE-1 | Antibody Specificity | Mannose - immunology | Disaccharides - metabolism | Humans | Antibodies, Neutralizing - metabolism | Crystallography, X-Ray | Disaccharides - chemistry | Mannosides - chemistry | HIV Envelope Protein gp120 - metabolism | HIV Envelope Protein gp120 - immunology | Mannose - metabolism | Antibodies, Neutralizing - immunology | HIV-1 - physiology | HIV Antibodies - immunology | Immunoglobulin Fab Fragments - metabolism | Oligosaccharides - chemistry | Polysaccharides - chemistry | HIV Envelope Protein gp120 - chemistry | Mannose - chemistry | HIV Antibodies - metabolism | Protein Structure, Tertiary | Cell Line | Models, Molecular | Antibodies, Neutralizing - genetics | Glycosylation | Polysaccharides - immunology | Oligosaccharides - metabolism | HIV Antibodies - chemistry | Polysaccharides - metabolism | HIV-1 - immunology | Hydrogen Bonding | Antibodies, Neutralizing - chemistry | Immunoglobulin Fab Fragments - chemistry | Oligosaccharides - immunology | Protein Conformation | Mannosides - metabolism | HIV Antibodies - genetics | Immunoglobulin Fab Fragments - immunology | Mutation | Binding Sites, Antibody | Carbohydrate Conformation | Viral antibodies | Physiological aspects | Development and progression | Glycoproteins | HIV (Viruses) | Health aspects | Proteins | Antigens | Immunoglobulins | Human immunodeficiency virus--HIV
Journal Article
2009, 1. Aufl., ISBN 0470117915, xv, 889
70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies...