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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 291 - 16
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 09/2017, Volume 19, Issue S1, pp. 76 - 89
Lipid metabolism dysregulation underlies chronic pathologies such as obesity, diabetes and cancer. Besides their role in structure and energy storage, lipids... 
metabolic syndrome | adipose browning | lipid metabolism | monoacylglycerol | ABHD6 | endocannabinoids | 2‐AG | insulin secretion | lipolysis | α/β Hydrolase domain containing 6 | energy metabolism | 2-AG | ADIPOSE TRIGLYCERIDE LIPASE | HORMONE-SENSITIVE LIPASE | Hydrolase domain containing 6 | HYDROLASE DOMAIN 6 | MONOGLYCERIDE LIPASE | ENDOCANNABINOID SYSTEM | STIMULATED INSULIN-SECRETION | GLUCAGON-LIKE PEPTIDE-1 | PROTEIN-COUPLED RECEPTOR | INTRACELLULAR LIPOLYSIS | ENDOCRINOLOGY & METABOLISM | CANNABINOID RECEPTOR-LIGAND | Endocannabinoids - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Obesity - drug therapy | Receptors, G-Protein-Coupled - metabolism | Monoacylglycerol Lipases - antagonists & inhibitors | Humans | Substrate Specificity | Metabolic Syndrome - metabolism | Monoacylglycerol Lipases - chemistry | Diabetes Mellitus, Type 2 - metabolism | Receptors, G-Protein-Coupled - agonists | Metabolic Syndrome - drug therapy | Monoacylglycerol Lipases - genetics | Monoacylglycerol Lipases - metabolism | TRPV Cation Channels - metabolism | Arachidonic Acids - metabolism | Peroxisome Proliferator-Activated Receptors - agonists | Peroxisome Proliferator-Activated Receptors - genetics | Metabolic Syndrome - enzymology | Second Messenger Systems - drug effects | Nerve Tissue Proteins - agonists | TRPV Cation Channels - agonists | Diabetes Mellitus, Type 2 - enzymology | Enzyme Inhibitors - pharmacology | Glycerides - metabolism | Organ Specificity | Enzyme Inhibitors - therapeutic use | Monoglycerides - metabolism | Nerve Tissue Proteins - genetics | TRPV Cation Channels - genetics | Obesity - metabolism | Nerve Tissue Proteins - metabolism | Animals | Models, Biological | Peroxisome Proliferator-Activated Receptors - metabolism | Ligands | Obesity - enzymology | Receptors, G-Protein-Coupled - genetics | Diabetes Mellitus, Type 2 - drug therapy | Energy Metabolism - drug effects | Lipase | Metabolism | Lipids
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e43962
The function of small intestinal monoacylglycerol lipase (MGL) is unknown. Its expression in this tissue is surprising because one of the primary functions of... 
DIACYLGLYCEROL ACYLTRANSFERASE | ENZYME | METABOLISM | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | MONOGLYCERIDE LIPASE | MICE | PLASMA LEPTIN | TRIGLYCERIDE SYNTHESIS | DIETARY-FAT INTAKE | RAT ADIPOSE-TISSUE | Endocannabinoids - metabolism | Basal Metabolism - physiology | Mice, Transgenic | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Agouti-Related Protein - metabolism | Obesity - genetics | Monoacylglycerol Lipases - genetics | Eating - physiology | Obesity - metabolism | Triglycerides - metabolism | Brain - metabolism | Neuropeptide Y - metabolism | Pro-Opiomelanocortin - metabolism | Monoacylglycerol Lipases - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Arachidonic Acids - metabolism | Animals | Adiposity - physiology | Appetite - physiology | Mice | Intestine, Small - metabolism | Energy Metabolism - physiology | Obesity | Physiological aspects | Genetic aspects | Research | Lipase | Endocannabinoids | Risk factors | Metabolic rate | Adipose tissue | Body fat | Mucosa | Body weight | Lipids | Genomes | Small intestine | Proteins | Energy | Transgenic animals | Rodents | Lean body mass | Enzymes | Phenotypes | Transgenic mice | Glycerol | Energy expenditure | Triglycerides | Metabolism | Gene expression | Fatty acids | Body weight gain | Energy balance | Overexpression | Diet | Body mass | Food intake | Insulin resistance | Diabetes
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2013, Volume 25, Issue 4, pp. 364 - 373
ALIX plays a role in nucleocapsid release during viral infection, as does lysobisphosphatidic acid (LBPA). However, the mechanism remains unclear. Here we... 
ENDOSOMES | ALIX/AIP1 | CYTOKINESIS | TRANSPORT | LIGAND DOCKING | ESCRT MACHINERY | HIV-1 RELEASE | DEVELOPMENTAL BIOLOGY | SEPARATION | MEMBRANE-PROTEINS | DOMAINS | CELL BIOLOGY | Lysophospholipids - metabolism | RNA, Small Interfering - genetics | Calcium - metabolism | Humans | Protein Multimerization | Endosomal Sorting Complexes Required for Transport - genetics | Molecular Sequence Data | Endosomes - metabolism | Virus Internalization | Escherichia coli - metabolism | Cell Cycle Proteins - genetics | Cell Membrane - metabolism | Phospholipids - metabolism | Binding Sites | Calcium-Binding Proteins - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Biophysical Phenomena | Protein Structure, Secondary | Cell Cycle Proteins - metabolism | Endosomal Sorting Complexes Required for Transport - metabolism | Models, Molecular | Recombinant Proteins - genetics | Monoglycerides - metabolism | Protein Interaction Mapping | Algorithms | Animals | Escherichia coli - genetics | Vesiculovirus - metabolism | Hydrophobic and Hydrophilic Interactions | Protein Binding | Cell Membrane - virology | Cytosol - metabolism | Liposomes - metabolism | HeLa Cells | Vesiculovirus - physiology | Calcium-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Virus diseases | Binding proteins | Health aspects | Infection control | Protein binding
Journal Article
Science, ISSN 0036-8075, 1/2004, Volume 303, Issue 5657, pp. 531 - 534
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2011, Volume 7, Issue 9, p. e1002232
The highly pathogenic Old World arenavirus Lassa virus (LASV) and the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) use a-dystroglycan as a... 
ALPHA-DYSTROGLYCAN | ENDOCYTIC PATHWAY | DENDRITIC CELLS | RECEPTOR | MICROBIOLOGY | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | VIROLOGY | LASSA FEVER | GROWTH-FACTOR | INFLUENZA-VIRUS | VESICULAR STOMATITIS-VIRUS | MONOCLONAL-ANTIBODIES | PARASITOLOGY | Lysophospholipids - metabolism | Vacuolar Proton-Translocating ATPases - genetics | Phosphatidylinositol Phosphates - metabolism | Receptors, Virus - metabolism | Humans | Cercopithecus aethiops | Dystroglycans - metabolism | Endosomal Sorting Complexes Required for Transport - genetics | Immunoblotting | Vacuolar Proton-Translocating ATPases - metabolism | Viral Proteins - metabolism | Endosomes - metabolism | Virus Internalization | DNA-Binding Proteins - metabolism | Endocytosis | Multivesicular Bodies - virology | Biological Transport | RNA Interference | Lymphocytic choriomeningitis virus - pathogenicity | HEK293 Cells | Real-Time Polymerase Chain Reaction | Cell Line | ATPases Associated with Diverse Cellular Activities | Cricetinae | Endosomal Sorting Complexes Required for Transport - metabolism | Viral Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Monoglycerides - metabolism | Lassa virus - pathogenicity | Transcription Factors - metabolism | Animals | Mutation | Transferrin - metabolism | Physiological aspects | Glycoproteins | Arenaviruses | Research | Health aspects | Cells | Biomedical research | Plasmids | Colleges & universities | Viruses | Grants | Experiments
Journal Article
Diabetologia, ISSN 0012-186X, 12/2016, Volume 59, Issue 12, pp. 2645 - 2653
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 09/2014, Volume 43, Issue 19, pp. 6859 - 6869
The endocannabinoid system, most popularly known as the target of the psychoactive component of marijuana, Delta super(9)-tetrahydrocannabinol (THC), is a... 
Networks | Enzymes | Inhibitors | Eyes | Derivatives | Lipase | Metabolism | Diseases
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 9/2014, Volume 43, Issue 19, pp. 6859 - 6869
Journal Article