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Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1241 - 1245
Aβ (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory... 
Oligomers | Yeasts | Endocytosis | Receptors | Neurons | Secretion | RESEARCH ARTICLES | Predisposing factors | Cell membranes | Alzheimers disease | Genetic screening | COMMON VARIANTS | CELLS | IDENTIFIES VARIANTS | MEMBRANE | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM | ALPHA-SYNUCLEIN | SACCHAROMYCES-CEREVISIAE | PEPTIDE | OLIGOMERS | GENOME-WIDE ASSOCIATION | Genetic Testing | Saccharomyces cerevisiae - genetics | Humans | Protein Multimerization | Secretory Pathway | Glutamates - metabolism | Saccharomyces cerevisiae - metabolism | Monomeric Clathrin Assembly Proteins - genetics | Amyloid beta-Peptides - genetics | Monomeric Clathrin Assembly Proteins - metabolism | Amyloid beta-Peptides - metabolism | Neurons - physiology | Cell Membrane - metabolism | Peptide Fragments - genetics | Peptide Fragments - metabolism | Caenorhabditis elegans - metabolism | Disease Susceptibility | Genetic Association Studies | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Risk Factors | Cells, Cultured | Rats | Saccharomyces cerevisiae Proteins - genetics | Clathrin - metabolism | Protein Transport | Saccharomyces cerevisiae - cytology | Peptide Fragments - chemistry | Animals | Caenorhabditis elegans - cytology | Alzheimer Disease - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cytoskeleton - metabolism | Amyloid beta-Peptides - chemistry | Alzheimer Disease - genetics | Saccharomyces cerevisiae - growth & development | Index Medicus | Basic Medicine | Other Basic Medicine | peptide | membrane | Medical and Health Sciences | Medicin och hälsovetenskap | oligomers | alpha-synuclein | saccharomyces cerevisiae | cells | identifies variants | Medicinska och farmaceutiska grundvetenskaper | Annan medicinsk grundvetenskap | genome-wide association | endoplasmic reticulum | common variants
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 42, pp. 17071 - 17076
Journal Article
by Deloukas, Panagiotis and Hamshere, Marian L and Lovestone, Simon and Mead, Simon and Nöthen, Markus M and Gerrish, Amy and O'Donovan, Michael and Hüll, Michael and Hardy, John and Hampel, Harald and Passmore, Peter A and Engelborghs, Sebastiaan and Abraham, Richard and Thomas, Charlene and Moskvina, Valentina and Brayne, Carol and Lawlor, Brian and Bass, Nicholas J and McQuillin, Andrew and Holmans, Peter A and Jones, Nicola and Pahwa, Jaspreet Singh and Morgan, Kevin and Klopp, Norman and Schürmann, Britta and Carrasquillo, Minerva M and Jessen, Frank and Tsolaki, Magda and McGuinness, Bernadette and Van Broeckhoven, Christine and De Deyn, Peter P and Cruchaga, Carlos and Mayo, Kevin and Wichmann, H-Erich and Brown, Kristelle S and Fox, Nick and Proitsi, Petroula and Mühleisen, Thomas W and Lupton, Michelle K and Lynch, Aoibhinn and Williams, Julie and Singleton, Andrew B and Moebus, Susanne and Dowzell, Kimberley and Livingston, Gill and Powell, John and Todd, Stephen and Wiltfang, Jens and Kornhuber, Johannes and Shaw, Christopher E and Pankratz, V Shane and Owen, Michael J and Holmes, Clive and Kehoe, Patrick G and Al-Chalabi, Ammar and Morgan, Angharad R and Heuser, Isabella and Williams, Amy and Mann, David and Gurling, Hugh and Kauwe, John S K and Goate, Alison M and Frölich, Lutz and Rubinsztein, David C and Love, Seth and Rossor, Martin and Rujescu, Dan and Hollingworth, Paul and Bettens, Karolien and Younkin, Steven G and Nowotny, Petra and Dichgans, Martin and Smith, A David and Collinge, John and van den Bussche, Hendrik and Gwilliam, Rhian and Guerreiro, Rita and Jöckel, Karl-Heinz and Sims, Rebecca and Morris, John C and Gill, Michael and Craig, David and Sleegers, Kristel and Harold, Denise and Stretton, Alexandra and Maier, Wolfgang
Nature Genetics, ISSN 1061-4036, 10/2009, Volume 41, Issue 10, pp. 1088 - 1093
Journal Article
Haematologica, ISSN 0390-6078, 2015, Volume 100, Issue 4, pp. 439 - 451
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 6/2009, Volume 185, Issue 6, pp. 1097 - 1110
Journal Article