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monophenol monooxygenase - antagonists & inhibitors (1449) 1449
index medicus (905) 905
monophenol monooxygenase - metabolism (863) 863
animals (789) 789
tyrosinase (674) 674
enzyme inhibitors - pharmacology (658) 658
humans (549) 549
biochemistry & molecular biology (505) 505
mice (504) 504
melanins - biosynthesis (411) 411
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chemistry, medicinal (394) 394
melanogenesis (363) 363
agaricales - enzymology (337) 337
kinetics (316) 316
pharmacology & pharmacy (303) 303
mushroom tyrosinase (293) 293
cell line, tumor (276) 276
mechanism (249) 249
plant extracts - pharmacology (243) 243
molecular structure (238) 238
melanin (223) 223
structure-activity relationship (222) 222
chemistry, applied (220) 220
pigmentation (209) 209
melanocytes - drug effects (206) 206
dose-response relationship, drug (204) 204
antioxidants - pharmacology (203) 203
dermatology (202) 202
skin (202) 202
food science & technology (199) 199
melanins - antagonists & inhibitors (194) 194
monophenol monooxygenase - chemistry (194) 194
plant extracts - chemistry (194) 194
acid (186) 186
melanins - metabolism (177) 177
cell survival - drug effects (174) 174
melanoma (174) 174
analysis (171) 171
melanocytes - metabolism (166) 166
inhibition (160) 160
chemistry, organic (156) 156
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monophenol monooxygenase - genetics (150) 150
enzyme inhibitors - isolation & purification (148) 148
in-vitro (144) 144
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antioxidant (140) 140
flavonoids (139) 139
cell biology (132) 132
melanocytes (131) 131
chemistry, multidisciplinary (127) 127
antioxidants (122) 122
derivatives (121) 121
inhibitory concentration 50 (119) 119
tyrosinase inhibitor (119) 119
kojic acid (118) 118
melanoma, experimental - metabolism (116) 116
cell line (115) 115
oxidation-reduction (115) 115
antioxidants - chemistry (114) 114
biotechnology & applied microbiology (113) 113
cells, cultured (109) 109
molecular docking simulation (106) 106
tyrosinase inhibitors (104) 104
skin pigmentation - drug effects (101) 101
inhibitors (100) 100
plant sciences (99) 99
tumor cells, cultured (95) 95
expression (91) 91
constituents (87) 87
antioxidant activity (86) 86
human melanocytes (86) 86
pyrones - pharmacology (83) 83
biosynthesis (82) 82
flavonoids - pharmacology (82) 82
melanocytes - enzymology (82) 82
skin - drug effects (82) 82
melanoma, experimental - pathology (80) 80
chemistry (78) 78
microphthalmia-associated transcription factor - metabolism (77) 77
models, molecular (76) 76
enzyme activation - drug effects (75) 75
phenols - pharmacology (75) 75
fungal proteins - antagonists & inhibitors (74) 74
melanoma - metabolism (74) 74
chromatography, high pressure liquid (73) 73
plant extracts - isolation & purification (73) 73
female (71) 71
proteins (70) 70
activation (69) 69
free radical scavengers - pharmacology (69) 69
agriculture, multidisciplinary (68) 68
catechol oxidase - antagonists & inhibitors (68) 68
free radicals (68) 68
plant leaves - chemistry (68) 68
protein binding (68) 68
enzyme inhibitors - metabolism (67) 67
melanocytes - cytology (67) 67
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Journal Article
PLOS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e91809
Condensed tannins from Ficus virens leaves, fruit, and stem bark were isolated and their structures characterized by C-13 nuclear magnetic resonance... 
SKIN PIGMENTATION | IN-VITRO | TOF MS ANALYSIS | MUSHROOM TYROSINASE | KINETICS | MULTIDISCIPLINARY SCIENCES | LEAVES | DOPAMINE | IONS | HPLC | RADICAL SCAVENGING ACTIVITY | Oxidoreductases - antagonists & inhibitors | Plant Extracts - chemistry | Plant Extracts - pharmacology | Molecular Conformation | Chelating Agents - chemistry | Models, Molecular | Substrate Specificity | Monophenol Monooxygenase - antagonists & inhibitors | Chelating Agents - pharmacology | Proanthocyanidins - chemistry | Copper - chemistry | Proanthocyanidins - pharmacology | Nuclear Magnetic Resonance, Biomolecular | Molecular Structure | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Catalysis | Ficus - chemistry | Monophenol Monooxygenase - chemistry | Polymerization | Biological products | Ionization | Mass spectrometry | Quinone | High performance liquid chromatography | Tannic acid | Procyanidins | Nuclear magnetic resonance--NMR | Enzyme activity | Molecular structure | Ecosystems | Bark | Fluorescence | Molecular docking | Fruits | Wetlands | Leaves | Quinones | Tannins | Enzymatic activity | Lasers | Education | Life sciences | Inhibition | Copper | Hydroxyl groups | Food | Spectroscopy | Enzymes | Free radicals | Ions | Mass spectroscopy | Desorption | Liquid chromatography | High-performance liquid chromatography | Quenching | Flavonoids | Phytochemicals | Molecular modelling | Inhibitors | Scientific imaging | Chelates | Tyrosinase | Nuclear magnetic resonance | NMR
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 07/2018, Volume 138, Issue 7, pp. 1601 - 1608
Tyrosinase is the rate-limiting enzyme of melanin production and, accordingly, is the most prominent target for inhibiting hyperpigmentation. Numerous... 
OXIDATION | MECHANISM | ACTIVE-SITE | 4-SUBSTITUTED RESORCINOLS | DEPIGMENTATION | 4-N-BUTYLRESORCINOL | RHODODENDROL | HYDROQUINONE | MAMMALIAN TYROSINASE | CYTOTOXICITY | DERMATOLOGY | Fungal Proteins - chemistry | Species Specificity | Monophenol Monooxygenase - isolation & purification | Skin - metabolism | Humans | Middle Aged | Skin Lightening Preparations - administration & dosage | Substrate Specificity | Male | Fungal Proteins - antagonists & inhibitors | Monophenol Monooxygenase - antagonists & inhibitors | Melanins - metabolism | Monophenol Monooxygenase - metabolism | Enzyme Inhibitors - administration & dosage | Recombinant Proteins - isolation & purification | Enzyme Inhibitors - chemistry | HEK293 Cells | Inhibitory Concentration 50 | Female | Molecular Structure | Skin Aging - physiology | Monophenol Monooxygenase - chemistry | High-Throughput Screening Assays - methods | Recombinant Proteins - metabolism | Drug Evaluation, Preclinical - methods | Tissue Culture Techniques | Skin Aging - drug effects | Enzyme Inhibitors - pharmacology | Recombinant Proteins - chemistry | Skin Lightening Preparations - chemistry | Hyperpigmentation - drug therapy | Treatment Outcome | Skin Lightening Preparations - pharmacology | Animals | Aged | Molecular Docking Simulation | Skin - drug effects | Agaricales - chemistry | Fungal Proteins - metabolism
Journal Article
Journal of Natural Products, ISSN 0163-3864, 02/2016, Volume 79, Issue 2, pp. 281 - 292
Journal Article
Journal Article