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Plant Molecular Biology, ISSN 0167-4412, 4/2003, Volume 51, Issue 6, pp. 925 - 948
The isoprenoid biosynthetic pathway provides intermediates for the synthesis of a multitude of natural products which serve numerous biochemical functions in... 
Life Sciences | Biochemistry, general | Plant Pathology | methylerythritol | Arabidopsis | chlorophyll | Plant Sciences | mevalonate | deoxyxylulose | isoprenoid | Methylerythritol | Chlorophyll | Mevalonate | Isoprenoid | Deoxyxylulose | CATALYZES 3 STEPS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | FARNESYL-DIPHOSPHATE SYNTHASE | ABSCISIC-ACID BIOSYNTHESIS | SYNECHOCYSTIS SP PCC-6803 | PLANT SCIENCES | RAB GERANYLGERANYL TRANSFERASE | NADPH-PROTOCHLOROPHYLLIDE OXIDOREDUCTASE | FUNCTIONAL EXPRESSION | PHYTOCHROME-CHROMOPHORE BIOSYNTHESIS | MOLECULAR-CLONING | Sesquiterpenes - metabolism | Ubiquinone - metabolism | Plastoquinone - metabolism | Vitamin K 1 - metabolism | Protein Prenylation | Terpenes - metabolism | Gibberellins - metabolism | Plastids - metabolism | Abscisic Acid - metabolism | Cholestanols - metabolism | Steroids, Heterocyclic - metabolism | Brassinosteroids | Chromosome Mapping | Mitochondria - metabolism | Chlorophyll - metabolism | Genome, Plant | Tocopherols - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Plastids - enzymology | Genes, Plant - genetics | Carotenoids - metabolism | Monoterpenes - metabolism | Phytosterols - metabolism | Dimethylallyltranstransferase - metabolism | Cytosol - metabolism | Chromosomes, Plant - genetics | Bacteria | Flowers & plants | Metabolism | Natural products
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49701
Paeoniflorin (PF), the principal component of Paeoniae Radix prescribed in traditional Chinese medicine, has been reported to exhibit many pharmacological... 
STROKE | ACTIVATION | PATHWAY | NEUROVASCULAR UNIT | MULTIDISCIPLINARY SCIENCES | FOCAL CEREBRAL-ISCHEMIA | INTRACEREBRAL HEMORRHAGE | NITRIC-OXIDE | MECHANISMS | EXPRESSION | NEUROPROTECTION | Microglia - metabolism | Tumor Necrosis Factor-alpha - blood | Tumor Necrosis Factor-alpha - genetics | Male | NF-kappa B - metabolism | Interleukin-1beta - genetics | Brain - metabolism | Inflammation - metabolism | Bridged-Ring Compounds - pharmacology | Monoterpenes | Neurons - metabolism | Disease Models, Animal | NF-kappa B - antagonists & inhibitors | bcl-2-Associated X Protein - metabolism | Rats | Brain - drug effects | Signal Transduction - drug effects | Brain Ischemia - drug therapy | Benzoates - pharmacology | Brain - pathology | Bridged-Ring Compounds - administration & dosage | Astrocytes - metabolism | Nitric Oxide Synthase Type II - metabolism | Cerebral Infarction - drug therapy | Brain Ischemia - metabolism | Cytochromes c - genetics | Hippocampus - drug effects | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Interleukin-1beta - blood | Proto-Oncogene Proteins c-bcl-2 - metabolism | Lipoxygenase - metabolism | Cerebral Infarction - metabolism | Inflammation - drug therapy | Neurons - drug effects | bcl-2-Associated X Protein - genetics | Cerebral Infarction - pathology | Astrocytes - drug effects | Glucosides - pharmacology | Microglia - drug effects | Cytochromes c - metabolism | Benzoates - administration & dosage | Gene Expression Regulation - drug effects | Animals | Glucosides - administration & dosage | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Cyclooxygenase 2 - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Mitogen-Activated Protein Kinases - metabolism | Occlusion | Neuroprotection | Brain | Inflammatory response | Activation | Kinases | Carotid arteries | Signal transduction | Chinese medicine | Ischemia | Neurodegeneration | Cerebral blood flow | Rodents | Tumor necrosis factor-TNF | Inhibition | NF-κB protein | Stroke | Cytokines | Astrocytes | Traditional Chinese medicine | Extracellular signal-regulated kinase | MAP kinase | JNK protein | Pharmacology | Inflammation | Tumor necrosis factor-α | IL-1β | Nitric-oxide synthase | Microglia | Signaling | Brain research | Liquid oxygen | Hypoxia | Brain damage | Cyclooxygenase-2 | Laboratory animals | Apoptosis | Veins & arteries
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 26, pp. 10865 - 10870
We identified a cis-prenyltransferase gene, neryl diphosphate synthase 1 (NDPS1). that is expressed in cultivated tomato (Solanum lycopersicum) cultivar M82... 
Enzymes | Sesquiterpenes | Genes | Monoterpenes | Trichomes | Biosynthesis | Diphosphates | Plants | Terpenes | Chromosomes | Terpene synthases | Specialized metabolism | Plant biochemistry | Cis-prenyltransferases | Biochemical diversity | ARABIDOPSIS-THALIANA | plant biochemistry | SAGE SALVIA-OFFICINALIS | MULTIDISCIPLINARY SCIENCES | DOLICHOL BIOSYNTHESIS | specialized metabolism | cis-prenyltransferases | terpene synthases | PYROPHOSPHATE SYNTHETASE | biochemical diversity | LYCOPERSICON-ESCULENTUM | CIS-PRENYLTRANSFERASE | CDNA ISOLATION | SESQUITERPENE BIOSYNTHESIS | KEY ENZYME | BACTERIAL EXPRESSION | Diphosphates - metabolism | Polyisoprenyl Phosphates - chemistry | Gas Chromatography-Mass Spectrometry | Alkyl and Aryl Transferases - metabolism | DNA, Complementary - genetics | Molecular Sequence Data | Substrate Specificity | Lycopersicon esculentum - enzymology | Organophosphorus Compounds - metabolism | Plant Epidermis - metabolism | Hemiterpenes - metabolism | Dimethylallyltranstransferase - genetics | Alkyl and Aryl Transferases - genetics | Cloning, Molecular | Gene Expression Regulation, Plant | Lycopersicon esculentum - genetics | Molecular Structure | Plant Proteins - metabolism | Diterpenes - metabolism | Plant Epidermis - enzymology | Diterpenes - chemistry | Hemiterpenes - chemistry | Lycopersicon esculentum - metabolism | Gene Library | Organophosphorus Compounds - chemistry | Biosynthetic Pathways | Reverse Transcriptase Polymerase Chain Reaction | Polyisoprenyl Phosphates - metabolism | Sequence Analysis, DNA | Diphosphates - chemistry | Plant Proteins - genetics | Monoterpenes - metabolism | Dimethylallyltranstransferase - metabolism | Monoterpenes - analysis | Monoterpenes - chemistry | DNA, Complementary - chemistry | Kinetics | Tomatoes | Chemical properties | Research | Pyrophosphates | Biological Sciences
Journal Article
Neuropharmacology, ISSN 0028-3908, 04/2017, Volume 116, pp. 412 - 420
Paeoniflorin (PF) is a major bioactive ingredient in roots that has low toxicity and has been shown to have neuroprotective effects. Our in vitro experiments... 
Paeoniflorin | Neuroprotective effect | Parkinson's disease | Phosphatidylinositol 3-kinase (PI3K)/Akt | OXIDATIVE STRESS | TYROSINE-HYDROXYLASE | SIGNAL PATHWAY | C57BL/6 MICE | KINASE | DEATH | DOPAMINERGIC NEUROTOXICITY | NEUROSCIENCES | ADENOSINE A RECEPTOR | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | PC12 CELLS | Dopamine Plasma Membrane Transport Proteins - metabolism | Motor Activity - physiology | Tyrosine 3-Monooxygenase - metabolism | Caspase 9 - metabolism | Substantia Nigra - pathology | Dopaminergic Neurons - pathology | Caspase 3 - metabolism | Motor Activity - drug effects | Male | Phosphatidylinositol 3-Kinases - metabolism | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Monoterpenes - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Neuroprotective Agents - pharmacology | Dopaminergic Neurons - metabolism | Dopaminergic Neurons - drug effects | MPTP Poisoning - pathology | bcl-Associated Death Protein - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Corpus Striatum - pathology | Cell Survival - physiology | Dopamine - metabolism | Cell Survival - drug effects | Monoamine Oxidase Inhibitors - pharmacology | Glucosides - pharmacology | Mice, Inbred C57BL | MPTP Poisoning - drug therapy | Substantia Nigra - drug effects | Animals | MPTP Poisoning - metabolism | Corpus Striatum - drug effects | Monoamine Oxidase - metabolism | Tyrosine | Analysis | Monoamine oxidase
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7322, pp. 461 - 467
Journal Article
The Plant Cell, ISSN 1040-4651, 12/2003, Volume 15, Issue 12, pp. 2866 - 2884
Volatile components, such as terpenoids, are emitted from aerial parts of plants and play a major role in the interaction between plants and their environment.... 
Leaves | Terpenoids | Sesquiterpenes | Monoterpenes | Biosynthesis | Plants | Flowers | Metabolism | Transgenic plants | Plastids | SESQUITERPENE CYCLASE GENE | S-LINALOOL | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT SCIENCES | CELL BIOLOGY | CDNA ISOLATION | ISOPRENOID BIOSYNTHESIS | THALIANA | FUNCTIONAL EXPRESSION | DIPHOSPHATE SYNTHASE | LINALOOL SYNTHASE GENE | GLANDULAR TRICHOMES | MONOTERPENE BIOSYNTHESIS | Aphids - growth & development | Sesquiterpenes - metabolism | Alkyl and Aryl Transferases - metabolism | Terpenes - chemistry | Terpenes - metabolism | Alkyl and Aryl Transferases - genetics | Volatilization | Gene Expression Regulation, Plant | Plant Proteins - metabolism | Chicory - metabolism | Hydroxylation | Plants, Genetically Modified - genetics | Sesquiterpenes, Germacrane - metabolism | Glycosylation | Polyisoprenyl Phosphates - metabolism | Chloroplasts - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Plant Proteins - genetics | Animals | Plants, Genetically Modified - metabolism | Monoterpenes - metabolism | Plants, Genetically Modified - parasitology | Monoterpenes - chemistry | Arabidopsis - parasitology | Arabidopsis | Genetically modified plants | Research | FaNES1 gene | isoprenoid biosynthesis | sesquiterpene cyclase gene | cdna isolation | glandular trichomes | thaliana | diphosphate synthase | monoterpene biosynthesis | linalool synthase gene | functional expression | s-linalool
Journal Article
Nature, ISSN 0028-0836, 12/2012, Volume 491, Issue 7427, pp. 138 - 142
Journal Article
Plant Cell, ISSN 1040-4651, 10/2015, Volume 27, Issue 10, pp. 2972 - 2990
Journal Article
New Phytologist, ISSN 0028-646X, 2016, Volume 209, Issue 2, pp. 679 - 690
Journal Article
Journal of Experimental Botany, ISSN 0022-0957, 1/2012, Volume 63, Issue 5, pp. 1951 - 1967
Flowers of the kiwifruit species produce a mixture of sesquiterpenes derived from farnesyl diphosphate (FDP) and monoterpenes derived from geranyl diphosphate... 
Enzymes | Terpenoids | Sesquiterpenes | Biosynthesis | Monoterpenes | Plants | Diphosphates | Flowers | Terpenes | Gross domestic product | RESEARCH PAPER | nerolidol | farnesol | Actinidia | terpene | terpene synthase | floral volatiles | kiwifruit | MOLECULAR-BIOLOGY | S-LINALOOL | TERPENOID BIOSYNTHESIS | PHOSPHATE-PATHWAY | PLANT SCIENCES | COA REDUCTASE | REDUCTASE-ACTIVITY | ISOPRENOID BIOSYNTHESIS | HIGHER-PLANTS | SNAPDRAGON FLOWERS | ALPHA-FARNESENE | Diphosphates - metabolism | Farnesol - metabolism | Sesquiterpenes - metabolism | Oils, Volatile - analysis | Flowers - metabolism | Alkyl and Aryl Transferases - metabolism | Molecular Sequence Data | Substrate Specificity | Phylogeny | Recombinant Proteins | Farnesol - analysis | Alkyl and Aryl Transferases - genetics | Sesquiterpenes - analysis | Base Sequence | Oils, Volatile - metabolism | Plant Proteins - metabolism | Actinidia - enzymology | Diterpenes - metabolism | Plant Leaves - enzymology | Flowers - enzymology | Tobacco - metabolism | Actinidia - metabolism | Gene Expression Regulation, Plant - genetics | Polyisoprenyl Phosphates - metabolism | Sequence Analysis, DNA | Arabidopsis - metabolism | Actinidia - genetics | Arabidopsis - genetics | Plant Proteins - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Tobacco - genetics | Monoterpenes - metabolism | Monoterpenes - analysis | Kinetics | Flowers - genetics | Research Papers
Journal Article