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European Journal of Neuroscience, ISSN 0953-816X, 04/2017, Volume 45, Issue 7, pp. 922 - 931
Although certain drugs of abuse are known to disrupt brain glucose metabolism (BGluM), the effects of opiates on BGluM are not well characterized. Moreover,... 
brain imaging | brain energy metabolism | opiate addition | drug self‐administration | drug self-administration | 2-DEOXYGLUCOSE | SMALL ANIMAL PET | NALOXONE | NEUROSCIENCES | ADDICTION | DEPENDENCE | POSITRON-EMISSION-TOMOGRAPHY | NUCLEUS | RECEPTORS | WITHDRAWAL | BRAIN | Anesthetics, Inhalation - pharmacology | Fluorodeoxyglucose F18 - pharmacokinetics | Radiopharmaceuticals - pharmacokinetics | Anesthetics, Inhalation - administration & dosage | Isoflurane - pharmacology | Morphine - pharmacology | Substance Withdrawal Syndrome - etiology | Anesthesia, Intravenous - adverse effects | Analgesics, Opioid - pharmacology | Rats | Isoflurane - adverse effects | Male | Anesthetics, Inhalation - adverse effects | Corpus Striatum - metabolism | Rats, Sprague-Dawley | Positron Emission Tomography Computed Tomography | Analgesics, Opioid - adverse effects | Animals | Analgesics, Opioid - administration & dosage | Corpus Striatum - drug effects | Corpus Striatum - diagnostic imaging | Morphine - administration & dosage | Morphine - adverse effects | Glucose metabolism | Brain research | PET imaging | Physiological aspects | Anesthesia | Morphine | Glucose | Dextrose | Cerebellum | Brain | Cortex (olfactory) | Drug abuse | Basal ganglia | Intravenous administration | Mesencephalon | Emission analysis | Stimulation | Opiates | Hypothalamus | Infusion | Computed tomography | Rodents | Neostriatum | Thalamus | Defecation | Jugular vein | Self-administration | Narcotics | Therapeutic applications | Positron emission | Injection | Metabolism | Isoflurane | Ganglia | Emissions control | Positron emission tomography | Hippocampus
Journal Article
The Journal of Bone & Joint Surgery, ISSN 0021-9355, 02/2013, Volume 95, Issue 4, pp. 291 - 296
BACKGROUND:Appropriate pain management affects outcome after hip fracture surgery. Although multimodal pain management is commonly used for pain control for... 
KNEE | SURGERY | DEMENTIA | TOTAL JOINT ARTHROPLASTY | DELIRIUM | HOSPITAL STAY | LOCAL INFILTRATION ANALGESIA | ELDERLY PATIENTS | ORTHOPEDICS | PUMP | CONSUMPTION | POSTOPERATIVE PAIN | Fentanyl - administration & dosage | Single-Blind Method | Hip Fractures - surgery | Pyrazoles - therapeutic use | Prospective Studies | Fentanyl - therapeutic use | Humans | Male | Adrenergic alpha-Agonists - therapeutic use | Arthroplasty, Replacement, Hip - methods | Adrenergic alpha-Agonists - administration & dosage | Epinephrine - therapeutic use | Cyclooxygenase 2 Inhibitors - therapeutic use | Statistics, Nonparametric | Aged, 80 and over | Anesthetics, Local - therapeutic use | Anesthetics, Local - administration & dosage | Oxycodone - therapeutic use | Oxycodone - administration & dosage | Cyclooxygenase 2 Inhibitors - administration & dosage | Pain Management - methods | Analgesics, Opioid - therapeutic use | Anti-Bacterial Agents - administration & dosage | Morphine - administration & dosage | Sulfonamides - administration & dosage | Ketorolac - therapeutic use | Pain, Postoperative - drug therapy | Epinephrine - administration & dosage | Patient Satisfaction | Anti-Bacterial Agents - therapeutic use | Cefmetazole - therapeutic use | Female | Drug Therapy, Combination | Analgesia, Patient-Controlled | Treatment Outcome | Amides - therapeutic use | Celecoxib | Chi-Square Distribution | Pyrazoles - administration & dosage | Sulfonamides - therapeutic use | Analgesics, Opioid - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Injections, Intra-Articular | Aged | Ketorolac - administration & dosage | Pain Measurement | Amides - administration & dosage | Morphine - therapeutic use | Cefmetazole - administration & dosage
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2009, Volume 157, Issue 5, pp. 831 - 843
Background and purpose:  Buprenorphine displays attributes of opioids, but also some features distinct from them. We examined spinal and supraspinal signal... 
mechanism of action | supraspinal | buprenorphine | analgesia (antinociception) | Supraspinal | Analgesia (antinociception) | Buprenorphine | Mechanism of action | MOLECULAR REARRANGEMENTS | OKADAIC-ACID | ANTISENSE OLIGODEOXYNUCLEOTIDES | MU-OPIOID RECEPTOR | INTRINSIC EFFICACY | SERINE/THREONINE PROTEIN PHOSPHATASES | PARTIAL AGONIST | PHARMACOLOGY & PHARMACY | MORPHINE-THEBAINE GROUP | TAIL-FLICK TEST | INDUCED ANTINOCICEPTION | Fentanyl - administration & dosage | Piperazines - administration & dosage | Narcotic Antagonists - administration & dosage | Serotonin Antagonists - administration & dosage | Phosphoprotein Phosphatases - metabolism | Aminoquinolines - administration & dosage | Injections, Intraventricular | Oligonucleotides, Antisense - metabolism | Male | Opioid Peptides - administration & dosage | Pain - chemically induced | Adrenergic alpha-Antagonists - administration & dosage | Pain - metabolism | GTP-Binding Proteins - genetics | Okadaic Acid - administration & dosage | Brain - metabolism | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Benzamides - administration & dosage | Pain Threshold - drug effects | Anesthetics, Local - administration & dosage | Pertussis Toxin - administration & dosage | Receptor, Serotonin, 5-HT1A - metabolism | Disease Models, Animal | Receptors, Opioid - metabolism | Injections, Spinal | Pyridines - administration & dosage | Pain - prevention & control | Phosphoprotein Phosphatases - antagonists & inhibitors | Yohimbine - administration & dosage | Brain - drug effects | Buprenorphine - administration & dosage | Animals | Signal Transduction - drug effects | Analgesics, Opioid - administration & dosage | Acetylcholine | Mice | Naloxone - administration & dosage | Pain Measurement | Morphine - administration & dosage | Receptors, Opioid - drug effects | Serotonin 5-HT1 Receptor Antagonists | GTP-Binding Proteins - metabolism | Index Medicus | Research Papers
Journal Article
Journal Article
ANAESTHESIA AND INTENSIVE CARE, ISSN 0310-057X, 06/2005, Volume 33, Issue 3, pp. 311 - 322
The clinical utility of most analgesic drugs is altered in the presence of patients with impaired renal or hepatic function not simply because of altered... 
acute pain | MORPHINE | ORTHOTOPIC LIVER-TRANSPLANTATION | CONTROLLED ANALGESIA | hepatic function | VALPROATE | CARBAMAZEPINE | FAILURE | DISPOSITION | PLASMA | PHARMACOKINETICS | hepatic failure | review | renal function | ANESTHESIOLOGY | REMIFENTANIL | analgesia : renal failure | CRITICAL CARE MEDICINE | Kidney Failure, Chronic - physiopathology | Analgesics - therapeutic use | Pain - drug therapy | Humans | Half-Life | Biological Availability | Metabolic Clearance Rate | Analgesics - pharmacokinetics | Liver Diseases - physiopathology | Liver Diseases - metabolism | Contraindications | Kidney Failure, Chronic - metabolism | Methadone, pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal, adverse effects | Piperidines, pharmacokinetics | Hydrocodone, pharmacokinetics | Fentanyl, pharmacokinetics | Pain, complications | Buprenorphine, pharmacokinetics | Hydrocodone, administration and dosage | Carbamazepine, pharmacokinetics | Acute Disease | Ketamine, pharmacokinetics | Sufentanil, pharmacokinetics | Propoxyphene, pharmacokinetics | Acetaminophen, adverse effects | Clonidine, administration and dosage | Morphine, administration and dosage | Oxycodone, administration and dosage | Propoxyphene, administration and dosage | Hydromorphone, administration and dosage | Methadone, administration and dosage | Alfentanil, pharmacokinetics | Buprenorphine, administration and dosage | Codeine, pharmacokinetics | Meperidine, pharmacokinetics | Sufentanil, administration and dosage | Anesthetics, Local, therapeutic use | Codeine, administration and dosage | Mexiletine, pharmacokinetics | Mexiletine, administration and dosage | Anti-Inflammatory Agents, Non-Steroidal, therapeutic use | Liver Failure, complications | Alfentanil, administration and dosage | Piperidines, administration and dosage | Pain, drug therapy | Ketamine, administration and dosage | Fentanyl, administration and dosage | Carbamazepine, administration and dosage | Hydromorphone, pharmacokinetics | Ketorolac, pharmacokinetics | Analgesics, Opioid, therapeutic use | Ketorolac, administration and dosage | Tramadol, administration and dosage | Morphine, pharmacokinetics | Valproic Acid, pharmacokinetics | Acetaminophen, administration and dosage | Valproic Acid, administration and dosage | Tramadol, pharmacokinetics | Acetic Acids | Kidney Failure, complications | Antidepressive Agents, Tricyclic, therapeutic use | Meperidine, administration and dosage | Clonidine, pharmacokinetics | Analgesics, Non-Narcotic, therapeutic use | Oxycodone, pharmacokinetics | Valproic Acid, adverse effects | Analgesia: renal failure, renal function, hepatic failure, hepatic function, review | Acute pain
Journal Article
JAMA, ISSN 0098-7484, 11/2003, Volume 290, Issue 18, pp. 2411 - 2418
Journal Article
Journal Article