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Developmental Biology, ISSN 0012-1606, 10/2012, Volume 370, Issue 2, pp. 237 - 249
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15181 - 15192
Journal Article
Cell Stem Cell, ISSN 1934-5909, 06/2016, Volume 18, Issue 6, pp. 769 - 781
Leber congenital amaurosis (LCA) is an inherited retinal dystrophy that causes childhood blindness. Photoreceptors are especially sensitive to an intronic... 
LEBER CONGENITAL AMAUROSIS | TRANSITION ZONE | GENE | MUTATION | TRANSCRIPTION | RETINA | MODEL | CEP290 | CENTROSOMAL PROTEIN | PHOTORECEPTORS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Leber Congenital Amaurosis - pathology | Optic Disk - cytology | Retinal Pigment Epithelium - metabolism | Humans | Blindness - pathology | Male | Organogenesis - drug effects | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Retinal Pigment Epithelium - pathology | Retinal Pigment Epithelium - ultrastructure | RNA Splicing - genetics | Antigens, Neoplasm - metabolism | Cilia - drug effects | Inheritance Patterns - genetics | Blindness - therapy | Induced Pluripotent Stem Cells - cytology | Neoplasm Proteins - genetics | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Retinal Pigment Epithelium - drug effects | rab GTP-Binding Proteins - metabolism | Antigens, Neoplasm - genetics | RNA Splicing - drug effects | Photoreceptor Cells, Vertebrate - ultrastructure | Induced Pluripotent Stem Cells - drug effects | RNA, Messenger - genetics | Exons - genetics | Fibroblasts - pathology | Cilia - metabolism | Eye Proteins - metabolism | Cell Differentiation - drug effects | Fibroblasts - drug effects | Morpholinos - pharmacology | Opsins - metabolism | Photoreceptor Cells, Vertebrate - metabolism | Photoreceptor Cells, Vertebrate - pathology
Journal Article
Development (Cambridge), ISSN 0950-1991, 06/2013, Volume 140, Issue 12, pp. 2632 - 2642
The first haematopoietic stem cells share a common origin with the dorsal aorta and derive from putative adult haemangioblasts in the dorsal lateral plate... 
Gene regulatory network | Haemangioblast | Haematopoietic stem cell | ETS | Scl | VEGF | TRANSCRIPTION FACTORS | VASCULAR DEVELOPMENT | ZEBRAFISH EMBRYOS | DEVELOPMENTAL BIOLOGY | EMBRYONIC BLOOD | HEMATOPOIETIC DEVELOPMENT | ENDOTHELIAL PROGENITORS | GENOME-WIDE ANALYSIS | GENE-EXPRESSION | FLK1 EXPRESSION | DORSAL AORTA | Hemangioblasts - cytology | Proto-Oncogene Proteins c-ets - genetics | Xenopus Proteins - genetics | Hemangioblasts - metabolism | Transcriptional Activation | Embryo, Nonmammalian - metabolism | Vascular Endothelial Growth Factor A - metabolism | Gene Regulatory Networks | Vascular Endothelial Growth Factor A - genetics | Embryo, Nonmammalian - drug effects | Somites - cytology | Vascular Endothelial Growth Factor Receptor-2 - genetics | DNA-Binding Proteins - metabolism | Proto-Oncogene Protein c-fli-1 - metabolism | Cloning, Molecular | Proto-Oncogene Proteins c-ets - metabolism | Xenopus laevis - blood | GATA2 Transcription Factor - genetics | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Somites - metabolism | Proto-Oncogene Protein c-fli-1 - genetics | Signal Transduction | Morpholinos - administration & dosage | Repressor Proteins - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Proto-Oncogene Proteins - genetics | Hematopoietic Stem Cells - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Blotting, Western | Transcription Factors - metabolism | Cell Lineage | Animals | Xenopus laevis - metabolism | Hematopoietic Stem Cells - cytology | GATA2 Transcription Factor - metabolism | Morpholinos - pharmacology | Xenopus Proteins - metabolism | Stem Cells and Regeneration
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132567
Mitochondrial flash (mitoflash) is a highly-conserved, universal, and physiological mitochondrial activity in isolated mitochondria, intact cells, and live... 
APOPTOSIS | SUPEROXIDE FLASHES | ELEMENT | INHIBITION | MULTIDISCIPLINARY SCIENCES | MOUSE | FISH ORYZIAS-LATIPES | PROLIFERATION | PERMEABILITY TRANSITION | Superoxide Dismutase - genetics | Mitochondrial Dynamics - genetics | Actins - metabolism | Muscle, Skeletal - metabolism | Muscular Dystrophies - genetics | Recombinant Fusion Proteins - metabolism | Time-Lapse Imaging | Actins - genetics | Gene Expression Regulation, Developmental | Muscle Proteins - metabolism | Muscle Proteins - antagonists & inhibitors | Membrane Proteins - metabolism | NADP - metabolism | Genes, Reporter | Superoxide Dismutase - metabolism | Disease Models, Animal | Muscular Dystrophies - metabolism | Morpholinos - genetics | Signal Transduction | Animals, Genetically Modified | Membrane Proteins - genetics | Zebrafish Proteins - metabolism | Zebrafish Proteins - antagonists & inhibitors | Bacterial Proteins - genetics | Zebrafish | Mitochondria - metabolism | Mitochondria - pathology | Muscular Dystrophies - pathology | Muscle Proteins - genetics | Morpholinos - metabolism | Animals | Membrane Proteins - antagonists & inhibitors | Embryo, Nonmammalian | Muscle Development - genetics | Recombinant Fusion Proteins - genetics | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Muscle, Skeletal - pathology | Zebrafish Proteins - genetics | Luminescent Proteins - metabolism | Muscles | Physiological aspects | Animal genetic engineering | Mitochondrial DNA | Biotechnology | Laboratories | Transgenic | Homeostasis | Cardiomyocytes | Permeability | Remodeling | Metabolism | Muscular dystrophy | Skeletal muscle | NAD | Medicine | Morphogenesis | Musculoskeletal system | Mitochondria | Bioenergetics | Rodents | Cell cycle | Genetics | Physiology | Life sciences | Dystrophy
Journal Article
Journal Article
Developmental Biology, ISSN 0012-1606, 01/2013, Volume 373, Issue 2, pp. 267 - 280
During lung development, proper epithelial cell arrangements are critical for the formation of an arborized network of tubes. Each tube requires a lumen, the... 
Scribble | Branching morphogenesis | Lumen | Polarity | PCP | Lung | LOCALIZATION | PROTEIN | NEURAL-TUBE DEFECTS | DEVELOPMENTAL BIOLOGY | MOUSE MUTANT | ADHESION | VANGL2 | DISRUPTION | INTERACTS | EXPRESSION | PLANAR POLARITY | Epithelial Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Epithelial Cells - drug effects | Zonula Occludens-2 Protein - metabolism | rhoA GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Protein Transport - drug effects | Lung - cytology | Adherens Junctions - metabolism | Gene Knockdown Techniques | Epithelium - embryology | Protein Binding - drug effects | Mammals - embryology | Cell Membrane - metabolism | Cell Polarity - drug effects | Lung - metabolism | Epithelial Cells - cytology | Imaging, Three-Dimensional | Cell Membrane - drug effects | Tight Junctions - drug effects | Tight Junctions - metabolism | Epithelium - drug effects | Epithelium - metabolism | beta Catenin - metabolism | Nerve Tissue Proteins - metabolism | Animals | Models, Biological | Lung - drug effects | Adherens Junctions - drug effects | Cell Communication - drug effects | Morpholinos - pharmacology | Cytoskeleton - metabolism | Morphogenesis - drug effects | Lung - embryology | Mice | Cytoskeleton - drug effects | Animal genetics | Proteins | Developmental biology | From the Society for Developmental Biology
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 12/2016, Volume 94, Issue 12, pp. 1373 - 1384
Cumulative evidence suggests the importance of organelle homeostasis in regulating metabolic functions in response to various cellular stresses. Particularly,... 
Human Genetics | Fis1 | Mitochondria | Biomedicine | Chondrocytes | Lysosome | Peroxisome | Internal Medicine | Zebrafish | Molecular Medicine | Osteoarthritis | Apoptosis | MEDICINE, RESEARCH & EXPERIMENTAL | LIPID-METABOLISM | CAUSES MITOCHONDRIAL | DISORDERS | AUTOPHAGY | DIVISION | CELL-DEATH | MESSENGER-RNA | BIOGENESIS | DISEASE | GENETICS & HEREDITY | DYSFUNCTION | RNA, Small Interfering - genetics | Apoptosis - drug effects | Humans | MicroRNAs - metabolism | Mitochondrial Proteins - genetics | Zebrafish - embryology | Autophagy - drug effects | Peroxisomes - drug effects | Chloroquine - pharmacology | Chondrocytes - drug effects | Lysosomes - metabolism | Cartilage, Articular - metabolism | Mitochondrial Proteins - metabolism | Membrane Proteins - metabolism | Osteoarthritis - pathology | Chondrocytes - metabolism | Lysosomes - drug effects | Chondrocytes - pathology | Lysosome-Associated Membrane Glycoproteins - metabolism | Morpholinos - genetics | Signal Transduction | Membrane Proteins - genetics | Mitochondrial Proteins - antagonists & inhibitors | Gene Expression Regulation | Osteoarthritis - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Osteoarthritis - genetics | Peroxisomes - metabolism | Zebrafish - genetics | Cartilage, Articular - pathology | Morpholinos - metabolism | Animals | Membrane Proteins - antagonists & inhibitors | Zebrafish - metabolism | Embryo, Nonmammalian | Lysosome-Associated Membrane Glycoproteins - genetics | MicroRNAs - genetics | Primary Cell Culture | Cartilage, Articular - drug effects | RNA, Small Interfering - metabolism | Gene mutations | Physiological aspects | Development and progression | Genetic aspects | Research | Cartilage cells
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1252 - 1258
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 2005
Journal Article
Nucleic Acid Therapeutics, ISSN 2159-3337, 06/2018, Volume 28, Issue 3, pp. 178 - 193
RNA interference (RNAi) is a fundamental cellular process for the posttranscriptional regulation of gene expression. RNAi can exogenously be modulated by small... 
miRNA | siRNA | oligonucleotides | Shiga toxin B-subunit | immunotherapy | checkpoint inhibitor | MEDICINE, RESEARCH & EXPERIMENTAL | IN-VIVO DELIVERY | CHEMISTRY, MEDICINAL | MOLECULAR-WEIGHT PROTAMINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSFECTION EFFICIENCY | ANTISENSE OLIGONUCLEOTIDE | CELL-PENETRATING PEPTIDES | SIRNA-BASED THERAPEUTICS | ENDOSOMAL ESCAPE | SMALL INTERFERING RNA | TOXIN T-DOMAIN | DUCHENNE MUSCULAR-DYSTROPHY | Neoplasms - metabolism | Oligonucleotides - chemistry | RNA, Small Interfering - genetics | Nanoparticles - chemistry | Humans | Oligonucleotides, Antisense - metabolism | MicroRNAs - metabolism | Endosomes - metabolism | Lipids - chemistry | Neoplasms - therapy | Biological Transport | Neoplasms - genetics | Amyloidosis - genetics | Nanoparticles - metabolism | Phosphorothioate Oligonucleotides - chemistry | Cell-Penetrating Peptides - chemistry | Gene Transfer Techniques | Amyloidosis - therapy | Amyloidosis - pathology | Peptide Nucleic Acids - metabolism | Morpholinos - chemistry | Morpholinos - metabolism | Oligonucleotides - metabolism | Animals | Oligonucleotides, Antisense - genetics | Cytosol - metabolism | Phosphorothioate Oligonucleotides - metabolism | MicroRNAs - genetics | Peptide Nucleic Acids - chemistry | Neoplasms - pathology | Amyloidosis - metabolism | Cell-Penetrating Peptides - metabolism | Genetic Therapy - methods | RNA, Small Interfering - metabolism | Translocation | Post-transcription | Enzymes | Peptides | RNA-mediated interference | Oligonucleotides | MiRNA | Lipids | Antisense oligonucleotides | Pharmacology | Biology | RNA polymerase | Nucleic acids | Gene expression | Chemical compounds | Nanoparticles | Proteins | Organic chemistry | Plasma proteins | Acids | Ribonucleic acids | Biomolecules | Pharmacokinetics
Journal Article
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2012, Volume 32, Issue 9, pp. E104 - E116
Objective-Endothelial sphingosine-1-phosphate (S1P) receptor-1 (S1P1) affects different vascular functions, including blood vessel maturation and permeability.... 
endothelial barrier | sphingosine-1-phosphate | zebrafish | Eph receptor | VE-cadherin | ANTAGONIST | ANGIOGENESIS | CHEMOTAXIS | VASCULAR-PERMEABILITY | SPHINGOSINE 1-PHOSPHATE | IN-VIVO | PERIPHERAL VASCULAR DISEASE | DIFFERENTIATION | HEMATOLOGY | CELL | EXPRESSION | Receptors, Lysosphingolipid - antagonists & inhibitors | Veins - embryology | Cadherins - metabolism | Cricetulus | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Oligonucleotides, Antisense - metabolism | Capillary Permeability - drug effects | Green Fluorescent Proteins - genetics | Phosphoproteins - metabolism | Zebrafish - embryology | Antigens, CD - metabolism | Transfection | RNA Interference | Gene Expression Regulation, Developmental | Receptors, Lysosphingolipid - genetics | Membrane Proteins - metabolism | Receptors, Lysosphingolipid - metabolism | CHO Cells | Tight Junctions - metabolism | Cricetinae | Human Umbilical Vein Endothelial Cells - drug effects | Animals, Genetically Modified | Endothelial Cells - metabolism | Zebrafish Proteins - metabolism | Zebrafish Proteins - antagonists & inhibitors | Receptor, EphB4 - metabolism | Zebrafish - genetics | Veins - drug effects | Morpholinos - metabolism | Organophosphonates - pharmacology | Animals | Zonula Occludens-1 Protein | Green Fluorescent Proteins - biosynthesis | Veins - metabolism | Zebrafish - metabolism | Anilides - pharmacology | Zebrafish Proteins - genetics | Endothelial Cells - drug effects
Journal Article