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1. Full Text Cancer in patients with motor neuron disease, multiple sclerosis and Parkinson's disease: record linkage studies
by Fois, Alessandro F and Wotton, Clare J and Yeates, David and Turner, Martin R and Goldacre, Michael J
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 02/2010, Volume 81, Issue 2, pp. 215 - 221
ObjectiveTo determine the risk of cancer before and after the diagnosis of motor neuron disease (MND), multiple sclerosis (MS) and Parkinson's disease... 
ANTIBODIES | SURGERY | DIAGNOSIS | MELANOMA | PSYCHIATRY | TUMOR | RISK | LYMPHOMA | SMOKING | AMYOTROPHIC-LATERAL-SCLEROSIS | CARCINOMA | CLINICAL NEUROLOGY | Parkinson Disease - pathology | Prevalence | Humans | Middle Aged | Male | Motor Neuron Disease - epidemiology | Multiple Sclerosis - epidemiology | Incidence | Motor Neuron Disease - pathology | Young Adult | Magnetic Resonance Imaging | Aged, 80 and over | Multiple Sclerosis - pathology | Parkinson Disease - epidemiology | Adult | Female | Aged | Neoplasms - pathology | Neoplasms - epidemiology | Multiple sclerosis | Parkinson's disease | Demographic aspects | Patient outcomes | Research | Risk factors | Cancer
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2. Full Text Global, regional, and national burden of motor neuron diseases 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
by Logroscino, Giancarlo and Piccininni, Marco and Marin, Benoît and Nichols, Emma and Abd-Allah, Foad and Abdelalim, Ahmed and Alahdab, Fares and Asgedom, Solomon Weldegebreal and Awasthi, Ashish and Chaiah, Yazan and Daryani, Ahmad and Do, Huyen Phuc and Dubey, Manisha and Elbaz, Alexis and Eskandarieh, Sharareh and Farhadi, Farzaneh and Farzadfar, Farshad and Fereshtehnejad, Seyed-Mohammad and Fernandes, Eduarda and Filip, Irina and Foreman, Kyle J and Gebre, Abadi Kahsu and Gnedovskaya, Elena V and Hamidi, Samer and Hay, Simon I and Irvani, Seyed Sina Naghibi and Ji, John S and Kasaeian, Amir and Kim, Yun Jin and Mantovani, Lorenzo Giovanni and Mashamba-Thompson, Tivani Phosa and Mehndiratta, Man Mohan and Mokdad, Ali H and Nagel, Gabriele and Nguyen, Trang Huyen and Nixon, Molly R and Olagunju, Andrew T and Owolabi, Mayowa Ojo and Piradov, Michael A and Qorbani, Mostafa and Radfar, Amir and Reiner, Robert C and Sahraian, Mohammad Ali and Sarvi, Shahabeddin and Sharif, Mehdi and Temsah, Omar and Tran, Bach Xuan and Truong, Nu Thi and Venketasubramanian, Narayanaswamy and Winkler, Andrea Sylvia and Yimer, Ebrahim M and Feigin, Valery L and Vos, Theo and Murray, Christopher J L and GBD 2016 Motor Neuron Dis Collabor and GBD 2016 Motor Neuron Disease Collaborators
The Lancet Neurology, ISSN 1474-4422, 12/2018, Volume 17, Issue 12, pp. 1083 - 1097
Understanding how prevalence, incidence, and mortality of motor neuron diseases change over time and by location is crucial for understanding the causes of... 
REDUCED FREQUENCY | POPULATION | SPINAL MUSCULAR-ATROPHY | PROGNOSIS | ALS | SMOKING | AMYOTROPHIC-LATERAL-SCLEROSIS | HEXANUCLEOTIDE REPEAT | EPIDEMIOLOGY | CLINICAL NEUROLOGY | FEATURES | Age Distribution | Prevalence | Global Burden of Disease - statistics & numerical data | Humans | Middle Aged | Male | Motor Neuron Disease - epidemiology | Cause of Death | Incidence | Life Expectancy | Bayes Theorem | Aged, 80 and over | Female | Aged | Disabled Persons | Medical research | Nervous system diseases | Neurons | Analysis | Mortality | Medicine, Experimental | Risk factors | Amyotrophic lateral sclerosis | Epidemiology | Spinal muscular atrophy | Studies | Hereditary spastic paraplegia | Paraplegia | Motor neuron diseases | Cell death | Paralysis | Spastic paraplegia | Health risk assessment | Bayesian analysis | Age | Life Sciences | Santé publique et épidémiologie
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3. Full Text Genetic epidemiology of motor neuron disease-associated variants in the Scottish population
by Black, Holly A and Leighton, Danielle J and Cleary, Elaine M and Rose, Elaine and Stephenson, Laura and Colville, Shuna and Ross, David and Warner, Jon and Porteous, Mary and Gorrie, George H and Swingler, Robert and Goldstein, David and Harms, Matthew B and Connick, Peter and Pal, Suvankar and Aitman, Timothy J and Chandran, Siddharthan
Neurobiology of Aging, ISSN 0197-4580, 2017, Volume 51, pp. 178.e11 - 178.e20
Abstract Genetic understanding of motor neuron disease (MND) has evolved greatly in the past 10 years, including the recent identification of association... 
Neurology | Internal Medicine | Amyotrophic lateral sclerosis | NEK1 | TBK1 | Motor neuron disease | EL-ESCORIAL | REPEAT EXPANSION | FRONTOTEMPORAL DEMENTIA | PHENOTYPE | CLINICAL CHARACTERISTICS | AMYOTROPHIC-LATERAL-SCLEROSIS | C9ORF72 | NEUROSCIENCES | FAMILIAL ALS | GERIATRICS & GERONTOLOGY | MUTATIONS | SUPEROXIDE-DISMUTASE | Genetic Predisposition to Disease - genetics | Genetic Association Studies | Humans | Middle Aged | Protein-Serine-Threonine Kinases - genetics | Genotype | Male | Scotland - epidemiology | Motor Neuron Disease - epidemiology | Young Adult | Phenotype | Motor Neuron Disease - genetics | Adolescent | Age of Onset | Aged, 80 and over | Adult | Female | Aged | Genetic Variation - genetics | NIMA-Related Kinase 1 - genetics | Genetic research | Neurons | Epidemiology | Medicine, Experimental | Medical research | Genetic Report Abstract
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4. Full Text Population based epidemiology of amyotrophic lateral sclerosis using capture–recapture methodology
by Huisman, Mark H B and de Jong, Sonja W and van Doormaal, Perry T C and Weinreich, Stephanie S and Schelhaas, H Jurgen and van der Kooi, Anneke J and de Visser, Marianne and Veldink, Jan H and van den Berg, Leonard H
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 10/2011, Volume 82, Issue 10, pp. 1165 - 1170
BackgroundVariation in the incidence rate in epidemiological studies on amyotrophic lateral sclerosis (ALS) may be due to a small population size and under... 
SURVIVAL | SURGERY | COUNTIES | IRELAND | PSYCHIATRY | ALS | COHORT | MOTOR-NEURON DISEASE | PREVALENCE | KIFAP3 | FRANCE | CLINICAL NEUROLOGY | Bulbar Palsy, Progressive - epidemiology | Prospective Studies | Age Factors | Cross-Sectional Studies | Humans | Middle Aged | Muscular Atrophy, Spinal - epidemiology | Male | Motor Neuron Disease - epidemiology | Incidence | Netherlands | Sex Factors | Female | Aged | Population Surveillance | Amyotrophic Lateral Sclerosis - epidemiology | Cohort Studies | Amyotrophic lateral sclerosis | Diagnosis | Research | Epidemiology
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5. Full Text Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study
by van Blitterswijk, Marka, PhD and DeJesus-Hernandez, Mariely, BS and Niemantsverdriet, Ellis, BS and Murray, Melissa E, PhD and Heckman, Michael G, MS and Diehl, Nancy N, BS and Brown, Patricia H, MS and Baker, Matthew C, BSc and Finch, NiCole A, MS and Bauer, Peter O, PhD and Serrano, Geidy, PhD and Beach, Thomas G, Prof and Josephs, Keith A, Prof and Knopman, David S, Prof and Petersen, Ronald C, Prof and Boeve, Bradley F, Prof and Graff-Radford, Neill R, Prof and Boylan, Kevin B, MD and Petrucelli, Leonard, Prof and Dickson, Dennis W, Prof and Rademakers, Rosa, Dr
Lancet Neurology, The, ISSN 1474-4422, 2013, Volume 12, Issue 10, pp. 978 - 988
Summary Background Hexanucleotide repeat expansions in chromosome 9 open reading frame 72 ( C9ORF72 ) are the most common known genetic cause of frontotemporal... 
Neurology | Frontotemporal Dementia - genetics | Cross-Sectional Studies | Frontal Lobe - metabolism | Comorbidity | DNA Repeat Expansion - genetics | Cerebellum - metabolism | Humans | Middle Aged | Genotype | Male | Motor Neuron Disease - epidemiology | Cerebellum - pathology | Motor Neuron Disease - pathology | Proteins - genetics | Phenotype | Motor Neuron Disease - genetics | Age of Onset | Female | Aged | C9orf72 Protein | Frontotemporal Dementia - epidemiology | Frontal Lobe - pathology | Cohort Studies | Frontotemporal Dementia - pathology | Neurosciences | Dementia
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6. Full Text Toward an epidemiology of poststroke spasticity
by Wissel, Jörg and Manack, Aubrey and Brainin, Michael
Neurology, ISSN 0028-3878, 01/2013, Volume 80, Issue 3, pp. S13 - S19
Poststroke spasticity (PSS)-related disability is emerging as a significant health issue for stroke survivors. There is a need for predictors and early... 
RECOVERY | MUSCLE | TIME-COURSE | PREVALENCE | SCALE | 1ST-EVER STROKE | ISCHEMIC-STROKE | ASSOCIATION | VALIDITY | CLINICAL NEUROLOGY | Muscle Spasticity - psychology | Prevalence | Humans | Stroke - complications | Motor Neuron Disease - epidemiology | Muscle Spasticity - therapy | Time Factors | Disabled Persons - statistics & numerical data | Stroke - epidemiology | Contracture - prevention & control | Stroke - therapy | Psychomotor Performance | Severity of Illness Index | Muscle Spasticity - epidemiology | Acute Disease | Stroke - psychology | Risk Factors | Motion Therapy, Continuous Passive | Treatment Outcome | Disabled Persons - psychology | Muscle Spasticity - etiology | Disabled Persons - rehabilitation | Muscle Spasticity - diagnosis | Quality of Life | Muscle Spasticity - physiopathology | Chronic Disease | Motor Neuron Disease - diagnosis | Adaptation, Psychological | Contracture - etiology
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7. Full Text Phenotypic heterogeneity of amyotrophic lateral sclerosis: a population based study
by Chiò, Adriano and Calvo, Andrea and Moglia, Cristina and Mazzini, Letizia and Mora, Gabriele and PARALS Study Grp and PARALS study group
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 07/2011, Volume 82, Issue 7, pp. 740 - 746
BackgroundDifferent amyotrophic lateral sclerosis (ALS) phenotypes have been recognised, marked by a varying involvement of spinal and bulbar upper and lower... 
SURGERY | DIAGNOSIS | PROGNOSTIC-FACTORS | PSYCHIATRY | ALS | CLINICAL-FEATURES | MODEL | NATURAL-HISTORY | CLINICAL NEUROLOGY | DISEASE ONSET | DEGENERATION | MUTATIONS | PROGRESSION | Age Factors | Amyotrophic Lateral Sclerosis - physiopathology | Humans | Middle Aged | Male | Motor Neuron Disease - epidemiology | Upper Extremity - innervation | Female | Registries | Lower Extremity - innervation | Motor Neuron Disease - etiology | Muscle Weakness - etiology | Dysarthria - etiology | Motor Neurons - physiology | Survival | Disease Progression | Upper Extremity - physiopathology | Phenotype | Amyotrophic Lateral Sclerosis - classification | Age of Onset | Sex Factors | Lower Extremity - physiopathology | Tracheostomy | Aged | Respiratory Mechanics | Amyotrophic Lateral Sclerosis - epidemiology | Motor neurons | Care and treatment | Analysis | Physiological aspects | Amyotrophic lateral sclerosis | Research
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8. Full Text Small-fiber neuropathy in patients with ALS
by Weis, J and Katona, I and Müller-Newen, G and Sommer, C and Necula, G and Hendrich, C and Ludolph, A.C and Sperfeld, A.-D
Neurology, ISSN 0028-3878, 06/2011, Volume 76, Issue 23, pp. 2024 - 2029
Objective: To investigate the involvement of the epidermal small sensory fibers in the neurodegenerative process in amyotrophic lateral sclerosis (ALS).... 
PERIPHERAL MOTOR | AXONAL SWELLINGS | DISTAL AXONOPATHY | EPIDERMAL NERVE-FIBERS | MOUSE MODEL | NORMATIVE-REFERENCE | AMYOTROPHIC-LATERAL-SCLEROSIS | MOTOR-NEURON DISEASE | SKIN BIOPSY | SENSORY NEURONS | CLINICAL NEUROLOGY | Motor Neuron Disease - etiology | Peripheral Nervous System Diseases - epidemiology | Peripheral Nervous System Diseases - etiology | Sensory Receptor Cells - pathology | Hereditary Sensory and Motor Neuropathy - pathology | Humans | Middle Aged | Male | Motor Neuron Disease - epidemiology | Skin Diseases - pathology | Amyotrophic Lateral Sclerosis - complications | Motor Neuron Disease - pathology | Skin Diseases - etiology | Amyotrophic Lateral Sclerosis - pathology | Hereditary Sensory and Motor Neuropathy - etiology | Nerve Fibers, Myelinated - pathology | Adult | Female | Aged | Peripheral Nervous System Diseases - pathology | Skin Diseases - epidemiology | Amyotrophic Lateral Sclerosis - epidemiology | Hereditary Sensory and Motor Neuropathy - epidemiology
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9. Full Text Analysis of the CHCHD10 gene in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Spain
by Dols-Icardo, Oriol and Nebot, Irene and Gorostidi, Ana and Ortega-Cubero, Sara and Hernández, Isabel and Rojas-García, Ricard and García-Redondo, Alberto and Povedano, Monica and Lladó, Albert and Álvarez, Victoria and Sánchez-Juan, Pascual and Pardo, Julio and Jericó, Ivonne and Vázquez-Costa, Juan and Sevilla, Teresa and Cardona, Fernando and Indakoechea, Begoña and Moreno, Fermín and Fernández-Torrón, Roberto and Muñoz-Llahuna, Laia and Moreno-Grau, Sonia and Rosende-Roca, Maiteé and Vela, Álvaro and Muñoz-Blanco, José Luís and Combarros, Onofre and Coto, Eliecer and Alcolea, Daniel and Fortea, Juan and Lleó, Alberto and Sánchez-Valle, Raquel and Esteban-Pérez, Jesús and Ruiz, Agustín and Pastor, Pau and López De Munain, Adolfo and Pérez-Tur, Jordi and Clarimón, Jordi and Dementia Genetics Spanish Consorti and Dementia Genetics Spanish Consortium (DEGESCO)
Brain, ISSN 0006-8950, 12/2015, Volume 138, Issue 12, pp. e400 - U24
NEUROSCIENCES | CLINICAL NEUROLOGY | MUTATIONS | Frontotemporal Dementia - genetics | Motor Neuron Disease - complications | Amyotrophic Lateral Sclerosis - genetics | Humans | Male | Mitochondrial Proteins - genetics | Motor Neuron Disease - epidemiology | Case-Control Studies | Frontotemporal Dementia - complications | Motor Neuron Disease - genetics | Spain - epidemiology | Age of Onset | Female | Aged | Mutation | Frontotemporal Dementia - epidemiology | Amyotrophic Lateral Sclerosis - epidemiology
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10. Full Text Farming and incidence of motor neuron disease: French nationwide study
by Kab, S and Moisan, F and Elbaz, A
European Journal of Neurology, ISSN 1351-5101, 09/2017, Volume 24, Issue 9, pp. 1191 - 1195
Background and purpose The association of farming with motor neuron disease (MND) is unclear, with conflicting studies. We performed a French nationwide study... 
agriculture | epidemiology | motor neuron disease | Parkinson's disease | farmers | occupational | RISK-FACTORS | METAANALYSIS | PARKINSON DISEASE | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | CLINICAL NEUROLOGY | France - epidemiology | Risk Assessment | Humans | Middle Aged | Pesticides | Farmers - statistics & numerical data | Male | Motor Neuron Disease - epidemiology | Incidence | Agriculture - statistics & numerical data | Health Surveys | Smoking - epidemiology | Aged, 80 and over | Parkinson Disease - epidemiology | Adult | Female | Aged | Medical research | Farmers | National health insurance | Neurons | Analysis | Agricultural industry | Medicine, Experimental | Agriculture | Epidemiology | Sensitivity analysis | Neurodegenerative diseases | Adjustment | Motor task performance | Occupational exposure | Confidence intervals | Motor neuron diseases | Workers | Farms | Insurance | Risk assessment | Movement disorders | Smoking | Farming
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11. Full Text Geographic distributions of motor neuron disease mortality and well water use in U.S. counties
by Schwartz, Gary G and Rundquist, Bradley C and Simon, Isaac J and Swartz, Sami E
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 04/2017, Volume 18, Issue 3-4, pp. 279 - 283
Objective: We recently reported that U.S. mortality rates for motor neuron disease (MND) at the level of the state are associated with well water use. However,... 
well water | Amyotrophic lateral sclerosis | spatial epidemiology | UNITED-STATES | ENVIRONMENT | LEGIONNAIRES-DISEASE | AMYOTROPHIC-LATERAL-SCLEROSIS | AGREEMENT | CLINICAL NEUROLOGY | United States - epidemiology | Motor Neuron Disease - mortality | Prevalence | Humans | Water Supply | Motor Neuron Disease - epidemiology | Amyotrophic Lateral Sclerosis - epidemiology
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12. Full Text Motor neuron disease mortality rates in New Zealand 1992-2013
by Cao, Maize C and Chancellor, Andrew and Charleston, Alison and Dragunow, Mike and Scotter, Emma L
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 04/2018, Volume 19, Issue 3-4, pp. 285 - 293
Background: We determined the mortality rates of motor neuron disease (MND) in New Zealand over 22 years from 1992 to 2013. Previous studies have found an... 
New Zealand | epidemiology | motor neuron disease | amyotrophic lateral sclerosis | Mortality | UNITED-STATES | POPULATION | ALS | DEATH | TIME | AMYOTROPHIC-LATERAL-SCLEROSIS | CLINICAL NEUROLOGY | AGE | International Classification of Diseases | Meta-Analysis as Topic | Age Distribution | Humans | Middle Aged | Male | Motor Neuron Disease - epidemiology | Death Certificates | Motor Neuron Disease - mortality | Sex Factors | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Longitudinal Studies | New Zealand - epidemiology
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13. Full Text Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population‐based study
by Alonso, A and Logroscino, G and Jick, S. S and Hernán, M. A
European Journal of Neurology, ISSN 1351-5101, 06/2009, Volume 16, Issue 6, pp. 745 - 751
Background and purpose:  To estimate the incidence and lifetime risk of motor neuron disease (MND) in a population‐based sample in the United Kingdom.... 
lifetime risk | incidence | motor neuron disease | Lifetime risk | Motor neuron disease | Incidence | MORTALITY | ALS | AMYOTROPHIC-LATERAL-SCLEROSIS | VALIDITY | NEUROSCIENCES | PRACTICE RESEARCH DATABASE | CLINICAL NEUROLOGY | Age Distribution | Age Factors | Humans | Middle Aged | Risk Factors | Male | Motor Neuron Disease - epidemiology | Databases as Topic | Young Adult | Aged, 80 and over | Sex Distribution | Adult | Cause of Death - trends | Female | Aged | United Kingdom - epidemiology | Cohort Studies | Medicine, Experimental | Medical research | Family medicine | Physicians (General practice) | Neurons | Public health
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