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The Lancet (British edition), ISSN 0140-6736, 08/2016, Volume 388, Issue 10047, pp. 919 - 931
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 06/2010, Volume 107, Issue 29, pp. 13111 - 13116
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 06/2011, Volume 108, Issue 25, pp. 10337 - 10342
Spinal muscular atrophy (SMA), caused by the deletion of the SMN1 gene, is the leading genetic cause of infant mortality... 
Axons | Motor neurons | Growth cones | Neuroscience | Messenger RNA | RNA | Neurons | Antibodies | Gene expression regulation | SMN complex proteins | Neuritin | Local protein synthesis | Embryonic lethal abnormal vision drosophila-like 4 (ELAV-L4) | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | ELAV-Like Protein 4 | Humans | RNA, Messenger - metabolism | Zebrafish - embryology | Recombinant Fusion Proteins - metabolism | Embryo, Mammalian - anatomy & histology | Motor Neurons - cytology | Survival of Motor Neuron 1 Protein - genetics | Neuropeptides - genetics | Animals, Genetically Modified | RNA, Messenger - genetics | Cells, Cultured | ELAV Proteins - metabolism | Axons - metabolism | Neuropeptides - metabolism | Survival of Motor Neuron 1 Protein - metabolism | Nerve Tissue Proteins - genetics | GPI-Linked Proteins - metabolism | Motor Neurons - metabolism | Nerve Tissue Proteins - metabolism | Embryo, Mammalian - physiology | Animals | Axons - pathology | Recombinant Fusion Proteins - genetics | Zebrafish - physiology | Mice | ELAV Proteins - genetics | GPI-Linked Proteins - genetics | Gene mutations | Physiological aspects | Genetic aspects | Research | Health aspects | Risk factors | Spinal muscular atrophy | Index Medicus | Spinal cord | Translation | Cell survival | Mental disorders | Axonogenesis | Mortality | SMN protein | survival | Mass spectroscopy | Infants | Gene deletion | infant mortality | HuD protein | Proteins | Pathology | RNA-binding protein | Actin | Neuromuscular junctions | spinal muscular atrophy | Axon guidance | Mass spectrometry | Biological Sciences | neuritin | embryonic lethal abnormal vision Drosophila-like 4 (ELAV-L4) | local protein synthesis
Journal Article
Neurobiology of disease, ISSN 0969-9961, 03/2012, Volume 45, Issue 3, pp. 939 - 953
Abstract Parkinson's disease (PD) is characterised by the progressive loss of nigral dopamine neurons and the presence of synucleinopathy. Overexpression of α... 
Neurology | Motor deficit | Parkinson's disease | Adeno-associated viral vector | Rat | alpha-Synuclein | Alpha-Synuclein | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Dependovirus - genetics | Tyrosine 3-Monooxygenase - metabolism | Antiparkinson Agents - pharmacology | Vesicular Monoamine Transport Proteins - metabolism | Dopaminergic Neurons - pathology | Neurodegenerative Diseases - etiology | Cell Count | Humans | Stereotyped Behavior - drug effects | Green Fluorescent Proteins - genetics | Parkinson Disease - drug therapy | Chromatography, High Pressure Liquid | Antiparkinson Agents - therapeutic use | Time Factors | Dopaminergic Neurons - metabolism | Female | alpha-Synuclein - genetics | Dopamine - metabolism | Disease Models, Animal | Mesencephalon - pathology | Stereotyped Behavior - physiology | Levodopa - pharmacology | Parkinson Disease - complications | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation - genetics | Levodopa - therapeutic use | Amphetamine - pharmacology | ELAV Proteins - metabolism | Rats | Neurodegenerative Diseases - genetics | Parkinson Disease - genetics | Rats, Sprague-Dawley | Disease Progression | Nerve Tissue Proteins - metabolism | Behavioral Symptoms - genetics | Animals | Analysis of Variance | Genetic Vectors - physiology | alpha-Synuclein - metabolism | Regulatory Elements, Transcriptional - genetics | Behavioral Symptoms - etiology | Index Medicus | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 11/2011, Volume 31, Issue 46, pp. 16619 - 16636
.... Truncation mutation of the Dnmt3a catalytic domain and Dnmt3a RNAi blocked apoptosis of cultured neurons... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Propionates - pharmacology | Amyloid Precursor Protein Secretases - genetics | Cytosine - analogs & derivatives | RNA, Small Interfering - genetics | Central Nervous System - metabolism | Age Factors | Apoptosis - drug effects | 5-Methylcytosine - analogs & derivatives | Humans | Caspase 3 - metabolism | Gene Expression Regulation, Developmental - genetics | Apoptosis - genetics | Green Fluorescent Proteins - genetics | Aspartic Acid Endopeptidases - genetics | Central Nervous System - growth & development | Transfection | Epigenomics - methods | Cytosine - metabolism | Tryptophan - analogs & derivatives | Indoles - pharmacology | Superoxide Dismutase - metabolism | Disease Models, Animal | Motor Neurons - physiology | DNA (Cytosine-5-)-Methyltransferase 1 | Enzyme Inhibitors - pharmacology | Gene Expression Regulation, Developmental - drug effects | Sciatic Neuropathy - pathology | Mice, Transgenic | Up-Regulation - genetics | DNA Methylation - genetics | Mutation - genetics | Up-Regulation - drug effects | DNA (Cytosine-5-)-Methyltransferases - genetics | Amyloid Precursor Protein Secretases - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | Phthalimides | Aspartic Acid Endopeptidases - metabolism | Mice | Camptothecin - pharmacology | Sciatic Neuropathy - metabolism | Cell Line, Transformed | RNA, Small Interfering - metabolism | Index Medicus
Journal Article