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Nature, ISSN 0028-0836, 06/2010, Volume 465, Issue 7299, pp. 788 - 792
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 37, pp. 13535 - 13540
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 19, pp. 7499 - 7504
We describe a method for light-inducible and tissue-selective cell ablation using a genetically encoded photosensitizer, miniSOG (mini singlet oxygen... 
Locomotion | Motor neurons | Larvae | Genetic code | Interneurons | Neurons | Transgenic animals | Medical genetics | Fluorescence | Convulsions | Reactive oxygen species | Optogenetics | Pre-motor interneurons | Light inducible | ZEBRAFISH | PHOTOSENSITIZER | MULTIDISCIPLINARY SCIENCES | locomotion | optogenetics | SENSITIVITY | GLUTAMATE-RECEPTOR | TOXIN GENE | INACTIVATION | light inducible | pre-motor interneurons | reactive oxygen species | C-ELEGANS | EXPRESSION | TRANSGENIC MICE | CIRCUIT | Cell Death - radiation effects | Caenorhabditis elegans Proteins - metabolism | Neurons - cytology | Motor Neurons - radiation effects | Singlet Oxygen - metabolism | Caspases - metabolism | Time Factors | Light | Motor Neurons - cytology | Interneurons - cytology | Membrane Proteins - metabolism | Neurons - metabolism | Interneurons - radiation effects | Receptors, Nicotinic - metabolism | Caenorhabditis elegans - metabolism | Flavoproteins - metabolism | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Caspases - genetics | Flavoproteins - genetics | Membrane Proteins - genetics | Mitochondria - metabolism | Cell Survival - radiation effects | Motor Neurons - metabolism | Microscopy, Confocal | Animals | Caenorhabditis elegans - cytology | Interneurons - metabolism | Luminescent Proteins - genetics | Neurons - radiation effects | Caenorhabditis elegans Proteins - genetics | Dose-Response Relationship, Radiation | Receptors, Nicotinic - genetics | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Physiological aspects | Caenorhabditis elegans | Research | Active oxygen | Cells | Proteins | Nematodes | Amino acids | Oxygen | Index Medicus | Phagocytes | Mitochondria | Developmental stages | Acetylcholine receptors | Caspase | Illumination | Mutation | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 10/2004, Volume 431, Issue 7010, pp. 869 - 873
In Drosophila, a 'clock' situated in the brain controls circadian rhythms of locomotor activity. This clock relies on several groups of neurons that express... 
CIRCADIAN PACEMAKER CELLS | NERVOUS-SYSTEM | BEHAVIORAL RHYTHMS | GENE | MULTIDISCIPLINARY SCIENCES | PERIOD | MUTATION | NEUROPEPTIDE | OSCILLATIONS | PROJECTIONS | MELANOGASTER | Darkness | Motor Activity - physiology | Drosophila melanogaster - physiology | Drosophila Proteins - metabolism | Brain - physiology | Drosophila melanogaster - genetics | Behavior, Animal - radiation effects | Motor Activity - radiation effects | Biological Clocks - radiation effects | Light | Neurons - physiology | Neuropeptides - genetics | Circadian Rhythm - radiation effects | Drosophila melanogaster - radiation effects | Nuclear Proteins - genetics | Brain - cytology | Gene Expression | Circadian Rhythm - genetics | Behavior, Animal - physiology | Neuropeptides - metabolism | Nuclear Proteins - metabolism | Brain - radiation effects | Circadian Rhythm - physiology | Period Circadian Proteins | Motor Activity - genetics | Animals | Biological Clocks - physiology | Biological Clocks - genetics | Drosophila Proteins - genetics | Neurons - radiation effects | Proteins | Neurology | Peptides | Insects | Neurons | Circadian rhythm | Biological clocks | Index Medicus | Brain | Drosophila Proteins | Neurons and Cognition | Neuropeptides | Motor Activity | Circadian Rhythm | Nuclear Proteins | Behavior, Animal | Life Sciences | Biological Clocks | Drosophila melanogaster
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0169506 - e0169506
Differentiated neurons can be rapidly acquired, within days, by inducing stem cells to express neurogenic transcription factors. We developed a protocol to... 
MOTOR-NEURONS | OPTICAL CONTROL | IN-VITRO | MINIATURE SYNAPTIC EVENTS | VISUAL FUNCTION | MULTIDISCIPLINARY SCIENCES | FAMILIAL ALZHEIMERS-DISEASE | PATCH-CLAMP | AMPA RECEPTOR | ASTROGLIAL CELLS | HIPPOCAMPAL-NEURONS | Excitatory Postsynaptic Potentials - radiation effects | Electrophysiological Phenomena - radiation effects | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Synapses - radiation effects | Neurons - cytology | Synapsins - metabolism | Induced Pluripotent Stem Cells - radiation effects | Astrocytes - radiation effects | Synapses - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Time Factors | Light | Neurogenesis - radiation effects | Neurons - metabolism | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Astrocytes - cytology | Cell Differentiation - radiation effects | Cells, Cultured | Rats | Nerve Tissue Proteins - metabolism | Receptors, Kainic Acid - metabolism | Animals | Neurons - radiation effects | Astrocytes - metabolism | Gene expression | Neurons | Analysis | Stem cells | Medical research | Transcription factors | Maturation | Synaptogenesis | Glutamic acid receptors (ionotropic) | Spatial discrimination | Cultures | N-Methyl-D-aspartic acid receptors | Biophysics | Kinases | Neurogenesis | Neurogenin | Consortia | Antibiotics | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid | Temporal resolution | Cocaine | Glutamatergic transmission | Pluripotency | Neurotransmission | Synapses | Index Medicus
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2008, Volume 64, Issue 4, pp. 293 - 301
Background Depression and anxiety disorders have been linked to dysfunction of the hypothalamo-pituitary-adrenal (HPA) axis and structural changes within the... 
Psychiatry | unpredictable chronic mild stress | x-irradiation | Corticotrophin-releasing factor | fluoxetine | depression | vasopressin | ADULT HIPPOCAMPUS | PSYCHIATRY | corticotrophin-releasing factor | CHRONIC MILD STRESS | CEREBRAL METABOLITES | CELL-PROLIFERATION | MAJOR DEPRESSION | NEUROSCIENCES | PREFRONTAL CORTEX | FLUOXETINE TREATMENT | FACTOR RECEPTOR ANTAGONIST | HYDROCHLORIDE SSR125543A | DENTATE GYRUS | Depression - pathology | Motor Activity - drug effects | Male | Hemibody Irradiation - methods | Pyrrolidines - pharmacology | Depression - drug therapy | Hemibody Irradiation - adverse effects | Time Factors | Exploratory Behavior - radiation effects | Reaction Time - drug effects | Exploratory Behavior - drug effects | Thiazines - pharmacology | Behavior, Animal - drug effects | Indoles - pharmacology | Antidepressive Agents - pharmacology | Bromodeoxyuridine - metabolism | Neurons - drug effects | Hydrocarbons, Halogenated - pharmacology | Disease Models, Animal | Antidepressive Agents - classification | Hippocampus - pathology | Corticotropin-Releasing Hormone - metabolism | Antidepressive Agents - therapeutic use | Animals | Cell Count - methods | Analysis of Variance | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Biogenic Monoamines - metabolism | Neurons - radiation effects | Cell Proliferation - radiation effects | Reaction Time - radiation effects | Anxiety | Pituitary hormones | Stress (Psychology) | Fluoxetine | Analysis | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e40937 - e40937
Essentially any behavior in simple and complex animals depends on neuronal network function. Currently, the best-defined system to study neuronal circuits is... 
NERVOUS-SYSTEM | MANIPULATION | AVOIDANCE | MULTIDISCIPLINARY SCIENCES | SYNAPTIC-TRANSMISSION | ASH NEURONS | CHANNELRHODOPSIN-2 | OPTOGENETIC ANALYSIS | OPTICAL INTERROGATION | BEHAVIORS | CIRCUIT | Muscle Cells - drug effects | Optogenetics | Nerve Net - drug effects | Nerve Net - physiology | Cholinergic Neurons - physiology | Caenorhabditis elegans - physiology | Proton Pumps - pharmacology | Light | Neurons - physiology | Nociception - drug effects | Halorhodopsins - pharmacology | Nerve Net - radiation effects | Neurons - drug effects | Motor Neurons - drug effects | Archaeal Proteins - pharmacology | Locomotion - drug effects | Proton Pumps - radiation effects | Motor Neurons - physiology | Touch - drug effects | Cholinergic Neurons - drug effects | Caenorhabditis elegans - radiation effects | Muscle Cells - physiology | Animals | Caenorhabditis elegans - drug effects | Signal Transduction - drug effects | Muscle Cells - radiation effects | Fungal Proteins - pharmacology | Neurons - radiation effects | Neurons | Animal behavior | Nematoda | Membrane proteins | Protons | Bioengineering | Interneurons | Dopamine | Arches | Electrophysiology | Nervous system | Biochemistry | Interdisciplinary aspects | Ashes | Light (illumination) | Signaling | Microorganisms | Pumps | Neural networks | Rodents | Sensory neurons | Nematodes | Illumination | Life sciences | Behavior | Inhibition | Worms | Index Medicus
Journal Article