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Cancer Cell, ISSN 1535-6108, 04/2016, Volume 29, Issue 4, pp. 508 - 522
The childhood brain tumor, medulloblastoma, includes four subtypes with very different prognoses. Here, we show that paracrine signals driven by mutant... 
LUNG-CANCER | ANGIOGENESIS | ONCOLOGY | PATHWAY | IN-VIVO | VINCRISTINE | TUMOR | CNS | CENTRAL-NERVOUS-SYSTEM | SUBGROUPS | CHEMOTHERAPY | CELL BIOLOGY | Humans | Neoplasm Proteins - physiology | Cerebellar Neoplasms - blood supply | Culture Media, Conditioned - pharmacology | Genetic Vectors - therapeutic use | Medulloblastoma - secretion | Recombinant Fusion Proteins - metabolism | Endothelium, Vascular - ultrastructure | Cerebellar Neoplasms - secretion | Wnt Proteins - genetics | Membrane Proteins - physiology | Pericytes - pathology | Glucose Transporter Type 1 - physiology | Antineoplastic Agents - pharmacokinetics | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Vincristine - pharmacokinetics | Disease Models, Animal | Carrier Proteins - physiology | Cerebellar Neoplasms - drug therapy | Transduction, Genetic | Genetic Association Studies | Genotype | Mice, Transgenic | Cerebellar Neoplasms - genetics | Tight Junctions - ultrastructure | Animals | Wnt Signaling Pathway - drug effects | Endothelium, Vascular - metabolism | Paracrine Communication - drug effects | Vincristine - therapeutic use | Medulloblastoma - blood supply | Mice | Wnt Proteins - physiology | Medulloblastoma - drug therapy | Drug Resistance, Neoplasm - physiology | Medulloblastoma - classification | Blood-Brain Barrier | Chemotherapy | Medulloblastoma | Brain tumors | Genetic aspects | Permeability | Cells | Cancer | Neurophysiology | Endothelium | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7323, pp. 557 - 561
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2010, Volume 24, Issue 4, pp. 1023 - 1034
Recently T-helper 17 (Th17) cells were demonstrated to disrupt the blood-brain barrier (BBB) by the action of IL-17A. The aim of the present study was to... 
Neuroinflammation | Multiple sclerosis | Reactive oxygen species | LIGHT-CHAIN KINASE | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS LESIONS | multiple sclerosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROVESSEL ENDOTHELIAL-CELLS | T-CELL | SPHINGOSINE 1-PHOSPHATE | FREE-RADICALS | CELL BIOLOGY | MEDICAL PROGRESS | neuroinflammation | reactive oxygen species | IL-17 | BIOLOGY | CENTRAL-NERVOUS-SYSTEM | Reactive Oxygen Species - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Interleukin-17 - immunology | NADPH Oxidases - metabolism | Oxidative Stress - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | NADPH Oxidases - immunology | Interleukin-17 - pharmacology | Occludin | Antibodies, Neutralizing - immunology | Reactive Oxygen Species - immunology | T-Lymphocytes, Helper-Inducer - immunology | Membrane Proteins - metabolism | T-Lymphocytes, Helper-Inducer - pathology | Xanthine Oxidase - metabolism | Blood-Brain Barrier - immunology | Myosin-Light-Chain Kinase | Encephalomyelitis, Autoimmune, Experimental - pathology | T-Lymphocytes, Helper-Inducer - metabolism | Endothelial Cells - metabolism | Enzyme Inhibitors - pharmacology | Antibodies, Neutralizing - pharmacology | Membrane Proteins - immunology | Xanthine Oxidase - immunology | Down-Regulation - drug effects | Blood-Brain Barrier - metabolism | Naphthalenes - pharmacology | Azepines - pharmacology | Endothelial Cells - immunology | Blood-Brain Barrier - pathology | Interleukin-17 - metabolism | Animals | Interleukin-17 - antagonists & inhibitors | Down-Regulation - immunology | Mice | Mice, Inbred BALB C | Oxidative Stress - drug effects | Endothelial Cells - pathology | Cell Line, Transformed | Index Medicus
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6063, pp. 1727 - 1731
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2012, Volume 8, Issue 10, pp. e1002982 - e1002982
Plasmodium falciparum malaria is responsible for nearly one million annual deaths worldwide. Because of the difficulty in monitoring the pathogenesis of... 
INTERCELLULAR-ADHESION MOLECULE-1 | SEVERE FALCIPARUM-MALARIA | PARASITE SEQUESTRATION | MICROBIOLOGY | VASCULAR-PERMEABILITY | PLASMODIUM-BERGHEI INFECTION | TUMOR-NECROSIS-FACTOR | MURINE MALARIA | VIROLOGY | IN-VIVO | ENDOTHELIAL CELL-INTERACTIONS | CENTRAL-NERVOUS-SYSTEM | PARASITOLOGY | Malaria, Cerebral - pathology | Blood-Brain Barrier - physiopathology | Lymphocyte Function-Associated Antigen-1 - metabolism | Mice, Inbred CBA | Parasitemia | Plasmodium berghei - pathogenicity | Cerebral Hemorrhage - etiology | Disease Models, Animal | Lipopolysaccharide Receptors - biosynthesis | Propylene Glycols - pharmacology | Blood-Brain Barrier - immunology | Cerebral Hemorrhage - drug therapy | Fingolimod Hydrochloride | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Sphingosine - pharmacology | Blood-Brain Barrier - pathology | Plasmodium yoelii - pathogenicity | Sphingosine - analogs & derivatives | Animals | Malaria, Cerebral - drug therapy | Plasmodium falciparum - pathogenicity | Mice | Mice, Inbred BALB C | Benzamides | Neuroimmunomodulation | Immunology | Blood-brain barrier | Malaria | Cerebrum | Physiological aspects | Development and progression | Research | Virulence (Microbiology) | Health aspects | Coma | Pediatrics | Pathogenesis | Mortality | Time series | Parasites | Blood | Endothelium | Medicine | Pathology | Blood platelets | Fatalities | Arrests | Index Medicus
Journal Article