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1. Full Text Dendritic cells of the oral mucosa
by Hovav, A.-H
Mucosal Immunology, ISSN 1933-0219, 01/2014, Volume 7, Issue 1, pp. 27 - 37
The oral cavity contains distinct mucosal surfaces, each with its own unique distribution of dendritic cell (DC) subsets. In addition to tissue- specific... 
LICHEN-PLANUS | HUMAN GINGIVAL EPITHELIUM | REGIONAL LYMPH-NODES | REGULATORY T-CELLS | SJOGRENS-SYNDROME | NECROSIS-FACTOR-ALPHA | PERIPHERAL-BLOOD | IMMUNOLOGY | ALVEOLAR BONE LOSS | INFLAMMATORY PERIODONTAL-DISEASE | LANGERHANS CELLS | Smoking - adverse effects | Cell Communication - immunology | Gingiva - immunology | Mouth Diseases - immunology | Mouth Floor - metabolism | Dendritic Cells - immunology | Humans | Immunity, Mucosal | Mouth Mucosa - immunology | Immune Tolerance | Sjogren's Syndrome - immunology | Antigen Presentation - immunology | Lymphoid Tissue | Cell Movement - immunology | Aging - immunology | Gingiva - metabolism | Phenotype | Animals | Mouth Floor - immunology | T-Lymphocytes - metabolism | T-Lymphocytes - immunology | Mice | Dendritic Cells - metabolism
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2. Full Text Mapping of the lingual immune system reveals the presence of both regulatory and effector CD4+ T cells
by Mascarell, L and Lombardi, V and Zimmer, A and Louise, A and Tourdot, S and Van Overtvelt, L and Moingeon, P
Clinical & Experimental Allergy, ISSN 0954-7894, 12/2009, Volume 39, Issue 12, pp. 1910 - 1919
Summary Background Sublingual immunotherapy (SLIT) is safe and reduces both symptoms and medication requirements in patients with type I respiratory allergies.... 
mucosal CD4+ T cell | sublingual immunotherapy | CD103 | antigen presenting cells | mucosal immunity | Antigen presenting cells | Mucosal immunity | Mucosal CD4 | Sublingual immunotherapy | T cell | FC-EPSILON-RI | DENDRITIC CELLS | ALLERGIC RHINITIS | INDUCTION | IMMUNOLOGY | HUMAN ORAL-MUCOSA | mucosal CD4+T cell | ANTIGEN-SPECIFIC TOLERANCE | ALLERGY | STEADY-STATE | T-CELLS | IMMUNOLOGICAL CHANGES | Macrophages - chemistry | Granulocytes - cytology | Spleen - immunology | Antigen-Presenting Cells - cytology | Ovalbumin - immunology | Cell Count | Eosinophils - chemistry | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Peptide Fragments - immunology | Receptors, Antigen, T-Cell - immunology | Tongue - cytology | Mast Cells - chemistry | T-Lymphocytes, Regulatory - chemistry | Toll-Like Receptors - metabolism | Dendritic Cells - chemistry | Tongue - immunology | CD4-Positive T-Lymphocytes - metabolism | Mouth Mucosa - immunology | Mice, Transgenic | Spleen - cytology | Antigen-Presenting Cells - chemistry | Mouth Floor - cytology | Granulocytes - chemistry | Mice | Mice, Inbred BALB C | Receptors, Antigen, T-Cell - genetics | Antigens, Surface - analysis | Muscles - cytology | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Vaccination | Mouth Floor - immunology | Immune Tolerance - immunology | T-Lymphocyte Subsets - chemistry | T-Lymphocytes, Regulatory - cytology | Female | CD4-Positive T-Lymphocytes - chemistry | Mouth Mucosa - cytology | Muscles - immunology | Cytokines - metabolism | CD4-Positive T-Lymphocytes - cytology | Langerhans Cells - chemistry | Thymus Gland - cytology | Macrophages - cytology | Animals | T-Lymphocyte Subsets - metabolism | Mast Cells - cytology | Thymus Gland - immunology | Dendritic Cells - cytology | Eosinophils - cytology | Langerhans Cells - cytology
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3. Full Text Establishment and first characterization of a sublingual epithelial and immune cell co-culture model
by Vacher, Gaëlle and Sublet, Emmanuelle and Gurny, Robert and Borchard, Gerrit
International Journal of Pharmaceutics, ISSN 0378-5173, 03/2015, Volume 482, Issue 1-2, pp. 61 - 67
Co-cultures of human sublingual epithelial cell line, HO-1-u-1 and dendritic cells derived from peripheral blood monocytes form an immunocompetent model of the... 
HO-1-u-1 cells | Dendritic cells | Co-culture | Immunotherapy | Sublingual epithelium | HO-1-u-1 ?cells | IMMUNIZATION | RESPONSES | HO-1-u-1? cells | PARTICLES | ALLERGENS | PHARMACOLOGY & PHARMACY | HUMAN ORAL-MUCOSA | EXPRESSION | Cell Line | Coculture Techniques | Dendritic Cells - immunology | Humans | Epithelial Cells - ultrastructure | Virosomes - immunology | Orthomyxoviridae - immunology | Mouth Floor - cytology | Mouth Floor - immunology | Dendritic Cells - ultrastructure | Epithelial Cells - immunology | Dendritic Cells - cytology | Liposomes | Epithelial Cells - cytology | Cytokines - immunology | Analysis
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4. Incidence of odontogenic phlegmon associated with polymorphic variant 896A/G of gene TLR4, but not with 2258G/A of gene TLR2
by Kuong, Vu V'et and Avetikov, D S and Shlykova, O A and Izmaĭlova, O V and Kaĭdashev, I P
Klinichna khirurhiia, ISSN 0023-2130, 10/2014, Issue 10, p. 54
The problem actuality is caused by significant enhancement of the incidence rate for inflammatory diseases of the head and neck tissues, first of all of the... 
Genetic Predisposition to Disease | Mouth Floor - metabolism | Toll-Like Receptor 2 - genetics | Cellulitis - genetics | Cellulitis - pathology | Gene Frequency | Humans | Middle Aged | Mouth - immunology | Mouth - metabolism | Toll-Like Receptor 4 - genetics | Male | Toll-Like Receptor 4 - immunology | Cellulitis - immunology | Mouth Floor - pathology | Mouth Floor - immunology | DNA Mutational Analysis | Alleles | Mouth - pathology | Toll-Like Receptor 2 - immunology | Adult | Female | Polymorphism, Single Nucleotide
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5. Full Text Distinct expression of perforin and granzyme B in lip and oral cavity squamous cell carcinoma
by Costa, Nádia Lago and Gonçalves, Andréia Souza and Souza‐Lima, Nathália Caroline and Jaime‐Paiva, Luís Gustavo and Junqueira‐Kipnis, Ana Paula and Silva, Tarcília Aparecida and Mendonça, Elismauro Francisco and Batista, Aline Carvalho
Journal of Oral Pathology & Medicine, ISSN 0904-2512, 05/2011, Volume 40, Issue 5, pp. 380 - 384
J Oral Pathol Med (2011) 40: 380–384 Background:  Perforin and granzyme B (GB) are the main constituents of cytotoxic T‐lymphocyte granules, and they have... 
lip squamous cell carcinoma | granzyme B | perforin | oral squamous cell carcinoma | Lip squamous cell carcinoma | Granzyme B | Oral squamous cell carcinoma | Perforin | CANCER-PATIENTS | DENTISTRY, ORAL SURGERY & MEDICINE | PATHOLOGY | LYMPHOCYTES | Lichen Planus, Oral - metabolism | Carcinoma, Squamous Cell - metabolism | Humans | Middle Aged | Leukoplakia, Oral - metabolism | Male | Mouth Neoplasms - metabolism | Case-Control Studies | Mouth Floor - immunology | Statistics, Nonparametric | Adult | Female | Granzymes - biosynthesis | Lip Neoplasms - metabolism | Mouth Floor - metabolism | Lip Neoplasms - immunology | Carcinoma, Squamous Cell - immunology | Mouth Neoplasms - immunology | Cheilitis - metabolism | Mouth Mucosa - metabolism | T-Lymphocytes, Cytotoxic - chemistry | T-Lymphocytes, Cytotoxic - metabolism | Lymphocyte Count | Aged | Apoptosis - physiology | Perforin - biosynthesis | Immunohistochemistry | Proteins | Squamous cell carcinoma | Oncology, Experimental | Development and progression | Research | Public health | Cancer
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6. Full Text Sensitivity and Specificity of Fluorescent Immunoguided Neoplasm Detection in Head and Neck Cancer Xenografts
by Kulbersh, Brian D and Duncan, Ryan D and Magnuson, J. Scott and Skipper, Joni B and Zinn, Kurt and Rosenthal, Eben L
Archives of Otolaryngology–Head & Neck Surgery, ISSN 0886-4470, 05/2007, Volume 133, Issue 5, pp. 511 - 515
OBJECTIVES To determine whether fluorescently labeled anti–epidermal growth factor (EGFR) antibody could be used to detect residual disease and to guide... 
SURGERY | GROWTH-FACTOR RECEPTOR | CETUXIMAB | THERAPY | OTORHINOLARYNGOLOGY | LYMPH-NODES | ANTIBODY | COMBINATION | EXPRESSION | CARCINOMA | RADIATION | PLEURAL SPACE | Immunohistochemistry | Neoplasm, Residual - pathology | Staining and Labeling - methods | Diagnosis, Differential | Carcinoma, Squamous Cell - pathology | Fluorescent Antibody Technique - methods | Humans | Antibodies, Anti-Idiotypic - immunology | Transplantation, Heterologous | Carcinoma, Squamous Cell - immunology | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - immunology | Mouth Floor - pathology | Animals | Mouth Floor - immunology | Sensitivity and Specificity | Cell Line, Tumor | Neoplasm, Residual - immunology | Epidermal Growth Factor - immunology | Mice | Antibodies, Monoclonal - immunology | Disease Models, Animal | Usage | Patient outcomes | Xenotransplantation | Head and neck cancer | Fluorescent antibody technique | Research | Immunofluorescence
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7. Full Text Antigen-bearing dendritic cells from the sublingual mucosa recirculate to distant systemic lymphoid organs to prime mucosal CD8 T cells
by Hervouet, C and Luci, C and Bekri, S and Juhel, T and Bihl, F and Braud, V.M and Czerkinsky, C and Anjuère, F
Mucosal Immunology, ISSN 1933-0219, 2014, Volume 7, Issue 2, pp. 280 - 291
Effector T cells are described to be primed in the lymph nodes draining the site of immunization and to recirculate to effector sites. Sublingual immunization... 
IMMUNIZATION | NODES | IMMUNE-RESPONSES | IN-VIVO | MICE | IMMUNOLOGY | ANTIBODY-RESPONSES | B-SUBUNIT | LANGERHANS CELLS | CHOLERA-TOXIN | GENITAL-TRACT | Cell Communication - immunology | Dendritic Cells - immunology | Mouth Mucosa - immunology | Lymph Nodes - immunology | Lymphoid Tissue - immunology | Cell Movement - immunology | Mouth Floor | Animals | Time Factors | CD8-Positive T-Lymphocytes - metabolism | Antigens - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Dendritic Cells - metabolism
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8. Full Text Sublingual Immunotherapy
by Frew, Anthony J
The New England Journal of Medicine, ISSN 0028-4793, 05/2008, Volume 358, Issue 21, pp. 2259 - 2264
A 28-year-old man presents with allergic rhinitis, primarily due to grass pollen, that has not previously responded to antihistamines and nasal sprays. A trial... 
RHINITIS | MEDICINE, GENERAL & INTERNAL | EFFICACY | SAFETY | DOUBLE-BLIND | POLLEN | RHINOCONJUNCTIVITIS | GRASS ALLERGEN TABLETS | ANAPHYLAXIS | BURDEN | EXTRACT | Poaceae - immunology | Humans | Male | Pollen - immunology | Rhinitis, Allergic, Seasonal - immunology | Plant Extracts - administration & dosage | Rhinitis, Allergic, Seasonal - therapy | Mouth Floor | Allergens - immunology | Interleukins - immunology | Adult | Desensitization, Immunologic - methods | Plant Extracts - adverse effects | Case studies | Care and treatment | Diagnosis | Hay-fever | Health aspects | Immunotherapy | Ear diseases | Nose | Allergies
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9. Full Text Small oral squamous cell carcinomas with nodal lymphogenic metastasis show increased infiltration of M2 polarized macrophages – An immunohistochemical analysis
by Weber, Manuel and Büttner-Herold, Maike and Hyckel, Peter and Moebius, Patrick and Distel, Luitpold and Ries, Jutta and Amann, Kerstin and Neukam, Friedrich W and Wehrhan, Falk
Journal of Cranio-Maxillo-Facial Surgery, ISSN 1010-5182, 2014, Volume 42, Issue 7, pp. 1087 - 1094
Abstract Background In solid malignancies the influence of immunological parameters – especially of macrophages – on invasiveness, metastatic potential and... 
Surgery | oscc | Oral squamous cell carcinoma | Oral cancer | Macrophage polarization | Macrophage polarization oscc | SURGERY | PROGNOSIS | DENTISTRY, ORAL SURGERY & MEDICINE | TUMOR-ASSOCIATED MACROPHAGES | TARGETS | CANCER | EXPRESSION | PLASTICITY | Carcinoma, Squamous Cell - pathology | Cell Count | Humans | Middle Aged | Receptors, Cell Surface - analysis | Male | Antigens, CD - analysis | Mouth Floor - pathology | Neoplasm Grading | Lymphatic Metastasis - pathology | Female | Receptors, Scavenger - analysis | Chemotaxis - immunology | Macrophages - immunology | Cell Polarity - immunology | Epithelium - pathology | Macrophages - classification | Connective Tissue - pathology | Macrophages - pathology | Alveolar Process - pathology | CD11c Antigen - analysis | Receptors, Immunologic - analysis | Tongue Neoplasms - pathology | Antigens, Differentiation, Myelomonocytic - analysis | Mouth Neoplasms - pathology | Carcinoma, Squamous Cell - secondary | Neoplasm Staging | Squamous cell carcinoma | Metastasis | Macrophages | Analysis
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10. Full Text Effect of photobiomodulation treatment in the sublingual, radial artery region, and along the spinal column in individuals with multiple sclerosis: Protocol for a randomized, controlled, double-blind, clinical trial
by da Silva, Tamiris and da Silva, Fernanda Cordeiro and Gomes, Andréa Oliver and Viana, Ariane Oliveira and Gonçalves, Marcela Letícia Leal and Rodrigues, Maria Fernanda Setúbal Destro and Horliana, Anna Carolina Ratto Tempestini and da Silva, Daniela de Fátima Teixeira and Chavantes, Maria Cristina and Fragoso, Yara Dadalti and Branco, Luciana Prats and Motta, Lara Jansiski and Fernandes, Kristianne Porta Santos and Mesquita-Ferrari, Raquel Agnelli and Bussadori, Sandra Kalil
Medicine, ISSN 0025-7974, 05/2018, Volume 97, Issue 19, p. e0627
Background:Multiple sclerosis (MS) is an autoimmune disease, for which the forms of treatment are medication and rehabilitation. However, in vitro and in vivo... 
photobiomodulation | CELLS | MEDICINE, GENERAL & INTERNAL | multiple sclerosis | physical therapy | low-level laser therapy | oxidative stress | Low-Level Light Therapy - methods | Double-Blind Method | Mouth Floor - radiation effects | Humans | Monitoring, Physiologic - methods | Multiple Sclerosis - immunology | Spinal Cord - radiation effects | Inflammation - immunology | Oxidative Stress - radiation effects | Multiple Sclerosis - therapy | Research Design | Development and progression | Multiple sclerosis | Care and treatment | Patient outcomes | Methods | Phototherapy
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11. Full Text Severe anaphylaxis to kiwi fruit: Immunologic changes related to successful sublingual allergen immunotherapy
by Mempel, Martin and Rakoski, Jürgen and Ring, Johannes and Ollert, Markus
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 06/2003, Volume 111, Issue 6, pp. 1406 - 1409
  SPTs and serologic analysis for specific IgE against a variety of other allergens, including birch pollen and latex, showed negative results. Because of the... 
ANTIBODIES | DOUBLE-BLIND | POLLEN | RHINOCONJUNCTIVITIS | IMMUNOLOGY | ALLERGY | Allergens - therapeutic use | Anaphylaxis - etiology | Administration, Oral | Humans | Anaphylaxis - therapy | Actinidia - immunology | Actinidia - adverse effects | Blotting, Western | Fruit - adverse effects | Immunoglobulin E - blood | Cross Reactions | Plant Extracts - administration & dosage | Allergens - administration & dosage | Mouth Floor | Immunoglobulin E - immunology | Anaphylaxis - immunology | Adult | Anaphylaxis - diagnosis | Female | Plant Extracts - therapeutic use | Desensitization, Immunologic | Allergens | Allergy | Allergic reaction | Immunotherapy | Medical research | Allergies | Fruits
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12. Full Text The Expression of GM-CSF and Osteopontin in Immunocompetent Cells Precedes the Odontoblast Differentiation Following Allogenic Tooth Transplantation in Mice
by Saito, Kotaro and Nakatomi, Mitsushiro and Ida-Yonemochi, Hiroko and Kenmotsu, Shin-ichi and Ohshima, Hayato
Journal of Histochemistry & Cytochemistry, ISSN 0022-1554, 5/2011, Volume 59, Issue 5, pp. 518 - 529
Dental pulp elaborates both bone and dentin under pathological conditions such as tooth replantation/transplantation. This study aims to clarify the expression... 
Odontoblasts | Osteopontin | Histocompatibility antigens class II | Transplantation | Mice (inbred ICR) | Cell differentiation | Granulocyte macrophage colony-stimulating factor | Dental pulp | histocompatibility antigens class II | granulocyte macrophage colony-stimulating factor | DENTAL-PULP DIFFERENTIATION | RAT MOLARS | cell differentiation | HEALING-PROCESS | osteopontin | REGENERATION | TISSUE | dental pulp | REPLANTATION | mice (inbred ICR) | CELL BIOLOGY | RESPONSES | DENTINOGENESIS | transplantation | odontoblasts | CAVITY PREPARATION | MOUSE MOLARS | Immunohistochemistry | Molar - transplantation | Odontoblasts - metabolism | Dental Pulp - immunology | Dendritic Cells - immunology | Dentin - metabolism | Dental Pulp - cytology | Mice, Inbred ICR | Transplantation, Homologous | Molar - immunology | Macrophages - metabolism | Animals | In Situ Hybridization | Dentin - cytology | Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis | Molar - cytology | Osteopontin - biosynthesis | Histocompatibility Antigens Class II - metabolism | Cell Differentiation | Mice | Odontoblasts - cytology | Mouth Floor - surgery | Dendritic Cells - metabolism | Macrophages - immunology
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13. Full Text Extensive Sublingual Epidermoid Cyst - Diagnosis by Immunohistological Analysis and Proof by Podoplanin
by Assaf, AT and Heiland, M and Blessmann, M and Friedrich, RE and Zustin, J and Al-Dam, A
IN VIVO, ISSN 0258-851X, 03/2012, Volume 26, Issue 2, pp. 323 - 326
Aim: We present the case of a surgically treated 39-year-old man with diagnosis of a giant sublingual internal epidermoid cyst. Usually, such dermoid or... 
Epidermoid cyst | MEDICINE, RESEARCH & EXPERIMENTAL | FLOOR | MRI | MOUTH | DERMOID CYST | ENDOTHELIAL-CELLS | SQUAMOUS-CELL CARCINOMA | EXPRESSION | sublingual | podoplanin (D2-40) | Membrane Glycoproteins - analysis | Antibody Specificity | Mouth Diseases - surgery | Epidermal Cyst - surgery | Humans | Epidermal Cyst - diagnostic imaging | Mouth Diseases - diagnostic imaging | Epidermal Cyst - metabolism | Male | Immunoenzyme Techniques | Mouth Floor | Snoring - etiology | Epidermal Cyst - diagnosis | Adult | Deglutition Disorders - etiology | Membrane Glycoproteins - immunology | Mouth Diseases - metabolism | Antibodies, Monoclonal - immunology | Antibodies, Monoclonal, Murine-Derived - immunology | Epidermal Cyst - epidemiology | Radiography | Magnetic Resonance Imaging | Mouth Diseases - diagnosis | Epidermal Cyst - pathology | Biomarkers | Mouth Diseases - pathology | Podoplanin (D2-40) | Sublingual
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14. Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth
by Monteiro-Amado, Flávio and Castro-Silva, Igor Iuco and Lima, Cristina Jardelino de and Soares, Fernando Augusto and Kowalski, Luiz Paulo and Granjeiro, José Mauro
Brazilian dental journal, 2013, Volume 24, Issue 1, p. 3
The aim of this study was to evaluate the immunoexpression of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth... 
Humans | Middle Aged | Neovascularization, Pathologic | Male | Immunoenzyme Techniques | Matrix Metalloproteinase 9 - metabolism | Mouth Floor - pathology | Mouth Neoplasms - blood supply | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Statistics, Nonparametric | Aged, 80 and over | Microvessels | Adult | Female | Matrix Metalloproteinase 2 - analysis | Retrospective Studies | Mouth Neoplasms - enzymology | Carcinoma, Squamous Cell - enzymology | Matrix Metalloproteinase 2 - metabolism | Neoplasm Invasiveness | Kaplan-Meier Estimate | Matrix Metalloproteinase 9 - analysis | Platelet Endothelial Cell Adhesion Molecule-1 - analysis | Lymphatic Metastasis | Chi-Square Distribution | Carcinoma, Squamous Cell - immunology | Mouth Floor - blood supply | Mouth Neoplasms - immunology | Mouth Floor - enzymology | Carcinoma, Squamous Cell - blood supply | Aged | Neoplasm Staging
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15. Mandibular third molar displaced in the sublingual space: clinical management and medicolegal considerations
by Varvara, G and Murmura, G and Cardelli, P and De Angelis, D and Caputi, S and Sinjari, B and Piattelli, M
Journal of biological regulators and homeostatic agents, ISSN 0393-974X, 04/2016, Volume 30, Issue 2, pp. 609 - 613
This paper describes the management of a failed mandibular third molar extraction, resulting in tooth displacement in the sublingual space, the discussion of... 
cone-beam computed tomography | SURGERY | MEDICINE, RESEARCH & EXPERIMENTAL | accidental displacement | PHYSIOLOGY | mandibular third molar | medicolegal considerations | ENDOCRINOLOGY & METABOLISM | IMMUNOLOGY | Radiography, Panoramic | Foreign Bodies - diagnostic imaging | Mandible | Mouth Floor | Humans | Adult | Male | Foreign Bodies - therapy | Molar, Third | Cone-Beam Computed Tomography | Tooth Extraction - adverse effects
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16. Full Text Migration and immunological reaction after the administration of αGalCer-pulsed antigen-presenting cells into the submucosa of patients with head and neck cancer
by Kurosaki, Motoyoshi and Kurosaki, Motoyoshi and Horiguchi, Shigetoshi and Horiguchi, Shigetoshi and Yamasaki, Kazuki and Yamasaki, Kazuki and Uchida, Yoshitaka and Uchida, Yoshitaka and Motohashi, Shinichiro and Motohashi, Shinichiro and Nakayama, Toshinori and Nakayama, Toshinori and Sugimoto, Akira and Sugimoto, Akira and Okamoto, Yoshitaka and Okamoto, Yoshitaka
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 2/2011, Volume 60, Issue 2, pp. 207 - 215
Antigen-presenting cells (APCs) play a crucial role in the induction of immune responses. However, the optimal administration route of tumor-specific APCs for... 
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