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1. Full Text Therapy-induced tumour secretomes promote resistance and tumour progression
by Obenauf, Anna C and Zou, Yilong and Ji, Andrew L and Vanharanta, Sakari and Shu, Weiping and Shi, Hubing and Kong, Xiangju and Bosenberg, Marcus C and Wiesner, Thomas and Rosen, Neal and Lo, Roger S and Massagué, Joan
Nature (London), ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 368 - 372
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Clone Cells - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Proto-Oncogene Proteins c-fos - deficiency | Adenocarcinoma - metabolism | Anaplastic Lymphoma Kinase | Neoplasm Metastasis - drug therapy | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Proto-Oncogene Proteins c-akt - metabolism | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | ErbB Receptors - antagonists & inhibitors | Melanoma - pathology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Adenocarcinoma - drug therapy | Disease Progression | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Cell Movement - drug effects | Animals | Clone Cells - pathology | Metabolome - drug effects | Signal Transduction - drug effects | Neoplasm Metastasis - pathology | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Pharmaceutical research | Care and treatment | Oncology, Experimental | Dosage and administration | Research | Drug therapy | Drug resistance | Antineoplastic agents | Tumors | Cancer | Melanoma | Mutation | Metastasis | Kinases | Cancer therapies | Index Medicus
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2. Full Text Promotion of Dental Pulp Cell Migration and Pulp Repair by a Bioceramic Putty Involving FGFR-mediated Signaling Pathways
by Zhang, J and Zhu, L.X and Cheng, X and Lin, Y and Yan, P and Peng, B
Journal of dental research, ISSN 0022-0345, 6/2015, Volume 94, Issue 6, pp. 853 - 862
proto-oncogene proteins c-akt | extracellular signal-regulated MAP kinase | cell movement | focal adhesion kinase | JNK mitogen-activated protein kinase | dental pulp capping | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Receptors, Fibroblast Growth Factor - drug effects | Nanoparticles - chemistry | Stress Fibers - drug effects | Mitogen-Activated Protein Kinase 1 - drug effects | Mitogen-Activated Protein Kinase 3 - drug effects | Paxillin - drug effects | Pulp Capping and Pulpectomy Agents - pharmacology | Wound Healing - drug effects | Calcium Compounds - pharmacology | Silicates - pharmacology | JNK Mitogen-Activated Protein Kinases - drug effects | Dentinogenesis - drug effects | Cells, Cultured | Dental Pulp - cytology | Rats | Dental Pulp - drug effects | Materials Testing | Dentin, Secondary - drug effects | Focal Adhesion Kinase 1 - drug effects | Cell Movement - drug effects | Focal Adhesions - drug effects | Oxides - pharmacology | p38 Mitogen-Activated Protein Kinases - drug effects | Animals | Ceramics - chemistry | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Membrane Proteins - drug effects | Aluminum Compounds - pharmacology | Vinculin - drug effects | Drug Combinations | Proto-Oncogene Proteins c-akt - drug effects | Dentin | Fibroblast growth factor | Transcription factors | Vertical migrations | c-Jun protein | Extracellular signal-regulated kinase | MAP kinase | AKT protein | Kinases | Experiments | Cell adhesion & migration | Nanoparticles | Signal transduction | Protein kinase | Vinculin | Focal adhesion kinase | Immunofluorescence | Paxillin | Cell migration | Apoptosis | Fibroblast growth factor receptors | Dental pulp | Index Medicus | Dentistry
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3. Full Text Effects of Recombinant Dentin Sialoprotein in Dental Pulp Cells
by Lee, S.-Y and Kim, S.-Y and Park, S.-H and Kim, J.-J and Jang, J.-H and Kim, E.-C
Journal of dental research, ISSN 0022-0345, 4/2012, Volume 91, Issue 4, pp. 407 - 412
dental pulp | growth | differentiation | dentin sialoprotein | BMP-2 | noggin | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Bone Morphogenetic Proteins - antagonists & inhibitors | Bone Morphogenetic Protein 2 - drug effects | Phosphoproteins - pharmacology | Humans | Smad8 Protein - drug effects | Recombinant Proteins | Dose-Response Relationship, Drug | Tooth Calcification - drug effects | Transforming Growth Factor beta - drug effects | Time Factors | Sialoglycoproteins - pharmacology | Carrier Proteins - pharmacology | RNA, Messenger - drug effects | JNK Mitogen-Activated Protein Kinases - drug effects | Cell Line | NF-KappaB Inhibitor alpha | NF-kappa B - antagonists & inhibitors | Oncogene Protein v-akt - drug effects | Dental Pulp - cytology | Extracellular Matrix Proteins - pharmacology | Dental Pulp - drug effects | I-kappa B Proteins - drug effects | Alkaline Phosphatase - drug effects | Cell Movement - drug effects | Smad5 Protein - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Odontoblasts - drug effects | Transcription Factor RelA - drug effects | Cell Proliferation - drug effects | Smad1 Protein - drug effects | Cell proliferation | Dentin | Phosphorylation | Smad protein | Transcription factors | Calcium | AKT protein | mRNA | Kinases | Cell adhesion & migration | Proteins | Signal transduction | Cell growth | Mineralization | Dentin sialoprotein | NF-κB protein | Genetic disorders | Bone morphogenetic protein 2 | Tissue engineering | Extracellular signal-regulated kinase | c-Jun protein | MAP kinase | JNK protein | Dspp protein | Noggin protein | Cell differentiation | Gene expression | Nuclear transport | Stem cells | Mutation | Cell migration | Dental pulp | Index Medicus | Dentistry
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4. Full Text Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1
by Au Yeung, Chi Lam and Co, Ngai-Na and Tsuruga, Tetsushi and Yeung, Tsz-Lun and Kwan, Suet-Ying and Leung, Cecilia S and Li, Yong and Lu, Edward S and Kwan, Kenny and Wong, Kwong-Kwok and Schmandt, Rosemarie and Lu, Karen H and Mok, Samuel C
Nature communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, pp. 11150 - 11150
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Exosomes - drug effects | Exosomes - metabolism | Paclitaxel - pharmacology | Apoptosis - drug effects | Humans | Ovarian Neoplasms - pathology | MicroRNAs - metabolism | Adipocytes - drug effects | Ovarian Neoplasms - genetics | Stromal Cells - drug effects | Female | Ovarian Neoplasms - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Ovarian Neoplasms - drug therapy | Fibroblasts - metabolism | Neoplasm Invasiveness | Stromal Cells - metabolism | Fibroblasts - pathology | Adipocytes - pathology | Paclitaxel - therapeutic use | Apoptotic Protease-Activating Factor 1 - metabolism | Cell Movement - drug effects | Drug Resistance, Neoplasm - genetics | Adipocytes - metabolism | Fibroblasts - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Drug Resistance, Neoplasm - drug effects | Index Medicus
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5. Full Text Differential response of human adipose tissue-derived mesenchymal stem cells, dermal fibroblasts, and keratinocytes to burn wound exudates: Potential role of skin-specific chemokine CCL27
by Van Den Broek, Lenie J and Kroeze, Kim L and Waaijman, Taco and Breetveld, Melanie and Sampat-Sardjoepersad, Shakun C and Niessen, Frank B and Middelkoop, Esther and Scheper, Rik J and Gibbs, Susan
Tissue engineering. Part A, ISSN 1937-3341, 01/2014, Volume 20, Issue 1-2, pp. 197 - 209
Cell & Tissue Engineering | Engineering | Materials Science | Life Sciences & Biomedicine | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Cell Biology | Organ Specificity - drug effects | Fibroblasts - secretion | Humans | Adipose Tissue - cytology | Male | Monocytes - metabolism | Exudates and Transudates - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Adult | Wound Healing - drug effects | Chemokine CCL27 - metabolism | Fibroblasts - metabolism | Mesenchymal Stromal Cells - drug effects | Dermis - metabolism | Endothelial Cells - metabolism | Solubility | Keratinocytes - secretion | Mesenchymal Stromal Cells - metabolism | Mesenchymal Stromal Cells - secretion | Recombinant Proteins - pharmacology | Monocytes - drug effects | Cell Movement - drug effects | Keratinocytes - drug effects | Keratinocytes - metabolism | Burns - pathology | Fibroblasts - drug effects | Dermis - pathology | Cell Proliferation - drug effects | Endothelial Cells - drug effects | Wound healing | Cellular biology | Burns | Tissue engineering | Chemokines | Stem cells | Index Medicus | Original
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6. Full Text The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo
by Heine, Annkristin and Heine, Annkristin and Held, Stefanie Andrea Erika and Held, Stefanie Andrea Erika and Daecke, Solveig Nora and Daecke, Solveig Nora and Wallner, Stephanie and Wallner, Stephanie and Yajnanarayana, Sowmya Parampalli and Yajnanarayana, Sowmya Parampalli and Kurts, Christian and Kurts, Christian and Wolf, Dominik and Wolf, Dominik and Brossart, Peter and Brossart, Peter
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 7, pp. 1192 - 1202
Life Sciences & Biomedicine | Hematology | Science & Technology | Apoptosis - drug effects | Monocytes - cytology | Dendritic Cells - immunology | Humans | Monocytes - metabolism | Spleen - drug effects | T-Lymphocytes, Cytotoxic - drug effects | Flow Cytometry | Bone Marrow - metabolism | Dendritic Cells - drug effects | Dendritic Cells - metabolism | Bone Marrow - drug effects | Pyrazoles - pharmacology | T-Lymphocytes, Cytotoxic - immunology | Antigen-Presenting Cells - metabolism | Cytokines - metabolism | Antigen-Presenting Cells - drug effects | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Spleen - cytology | Cell Adhesion - drug effects | Antigen-Presenting Cells - immunology | Blotting, Western | Janus Kinases - antagonists & inhibitors | Monocytes - drug effects | Cell Movement - drug effects | Animals | Spleen - metabolism | T-Lymphocytes, Cytotoxic - metabolism | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | In Vitro Techniques | Index Medicus | Abridged Index Medicus
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7. Full Text Combined effects of mineral trioxide aggregate and human placental extract on rat pulp tissue and growth, differentiation and angiogenesis in human dental pulp cells
by Chang, Seok-Woo and Kim, Ji-Youn and Kim, Mi-Joo and Kim, Ga-Hyun and Yi, Jin-Kyu and Lee, Deok-Won and Kum, Kee-Yeon and Kim, Eun-Cheol
Acta odontologica Scandinavica, ISSN 0001-6357, 05/2016, Volume 74, Issue 4, pp. 298 - 306
odontogenic differentiation | Angiogenesis | human dental pulp cells | human placental extract | MTA | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Neovascularization, Physiologic - drug effects | Placental Extracts - therapeutic use | Humans | Capillaries - drug effects | Male | Silicates - therapeutic use | Aluminum Compounds - therapeutic use | Calcium Compounds - therapeutic use | MAP Kinase Kinase 4 - drug effects | Odontoblasts - cytology | Dental Pulp - blood supply | TOR Serine-Threonine Kinases - drug effects | Calcium Compounds - pharmacology | Silicates - pharmacology | Oxides - therapeutic use | Pulp Capping and Pulpectomy Agents - therapeutic use | Cell Line | Human Umbilical Vein Endothelial Cells - drug effects | Calcification, Physiologic - drug effects | Dental Pulp - cytology | Rats | Dental Pulp - drug effects | Dentin, Secondary - drug effects | Rats, Sprague-Dawley | Alkaline Phosphatase - drug effects | Placental Extracts - pharmacology | Cell Movement - drug effects | Oxides - pharmacology | p38 Mitogen-Activated Protein Kinases - drug effects | Animals | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Odontoblasts - drug effects | Aluminum Compounds - pharmacology | Cell Proliferation - drug effects | Mitogen-Activated Protein Kinases - drug effects | Drug Combinations | NF-kappa B - drug effects | Proto-Oncogene Proteins c-akt - drug effects | Index Medicus | Dentistry
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8. Full Text The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance
by Han, Fei and Li, Chien-Feng and Cai, Zhen and Zhang, Xian and Jin, Guoxiang and Zhang, Wei-Na and Xu, Chuan and Wang, Chi-Yun and Morrow, John and Zhang, Shuxing and Xu, Dazhi and Wang, Guihua and Lin, Hui-Kuan
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4728 - 16
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Human Umbilical Vein Endothelial Cells - metabolism | Calcium - metabolism | Humans | Carcinogenesis - metabolism | Glycolysis - drug effects | Neovascularization, Pathologic - pathology | Ubiquitination - drug effects | Adenylate Kinase - metabolism | Stress, Physiological - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Fibroblasts - metabolism | Cell Survival - drug effects | ErbB Receptors - metabolism | Enzyme Activation - drug effects | Phosphoserine - metabolism | S-Phase Kinase-Associated Proteins - metabolism | Disease Progression | Carcinogenesis - drug effects | Carcinogenesis - pathology | Cell Movement - drug effects | Animals | Signal Transduction - drug effects | Fibroblasts - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Kinase - metabolism | Cell Line, Tumor | Mice | Epidermal Growth Factor - pharmacology | Drug Resistance, Neoplasm - drug effects | Stresses | Phosphorylation | Animal models | Cell survival | AKT protein | Activation | Breast cancer | Glucose | Drug resistance | 1-Phosphatidylinositol 3-kinase | Ubiquitination | Epidermal growth factor | Skp2 protein | Calcium-binding protein | Tumorigenesis | Growth factors | Calmodulin | Ubiquitin-protein ligase | Calcium ions | Cancer | Tumors | Index Medicus
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9. Full Text Regeneration of Hippocampal Pyramidal Neurons after Ischemic Brain Injury by Recruitment of Endogenous Neural Progenitors
by Nakatomi, Hirofumi and Kuriu, Toshihiko and Okabe, Shigeo and Yamamoto, Shin-ichi and Hatano, Osamu and Kawahara, Nobutaka and Tamura, Akira and Kirino, Takaaki and Nakafuku, Masato
Cell (Cambridge), ISSN 0092-8674, 2002, Volume 110, Issue 4, pp. 429 - 441
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neural Pathways - drug effects | Recovery of Function - drug effects | Nerve Regeneration - physiology | Neuronal Plasticity - drug effects | Male | Dendrites - ultrastructure | Nerve Degeneration - metabolism | Neuronal Plasticity - physiology | Recovery of Function - physiology | Hippocampus - ultrastructure | Pyramidal Cells - drug effects | Organ Culture Techniques | Dendrites - drug effects | Synapses - drug effects | Neural Pathways - growth & development | Rats | Synapses - ultrastructure | Brain Ischemia - physiopathology | Cell Division - drug effects | Stem Cells - ultrastructure | Cell Division - physiology | Cell Movement - drug effects | Brain Ischemia - drug therapy | Nerve Regeneration - drug effects | Growth Substances - pharmacology | Pyramidal Cells - metabolism | Rats, Wistar | Microtubule-Associated Proteins - metabolism | Nerve Degeneration - physiopathology | Brain Ischemia - metabolism | Hippocampus - drug effects | Stem Cells - metabolism | Excitatory Postsynaptic Potentials - drug effects | Cell Movement - physiology | Excitatory Postsynaptic Potentials - physiology | Synapses - metabolism | Up-Regulation - physiology | Hippocampus - growth & development | Pyramidal Cells - ultrastructure | Dendrites - metabolism | Transcription Factors - genetics | Microscopy, Electron | Transcription Factors - metabolism | Up-Regulation - drug effects | Animals | Growth Substances - therapeutic use | Stem Cells - drug effects | Neural Pathways - ultrastructure | Nerve Degeneration - drug therapy | Neural circuitry | Neurons | Growth | Physiological aspects | Hippocampus (Brain) | Developmental neurology | Research | Index Medicus
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