X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
murf1 (183) 183
index medicus (156) 156
animals (128) 128
atrophy (84) 84
mice (83) 83
muscle proteins - metabolism (72) 72
cell biology (68) 68
muscle, skeletal - metabolism (67) 67
atrogin-1 (66) 66
ubiquitin-protein ligases - metabolism (61) 61
skeletal-muscle (60) 60
male (59) 59
gene-expression (56) 56
ubiquitin (56) 56
muscular atrophy - metabolism (55) 55
biochemistry & molecular biology (54) 54
tripartite motif proteins (53) 53
humans (51) 51
muscles (50) 50
muscle, skeletal - pathology (49) 49
proteins (49) 49
proteolysis (49) 49
muscle proteins - genetics (45) 45
gene expression (44) 44
musculoskeletal system (44) 44
physiology (44) 44
skeletal muscle (43) 43
ubiquitin ligases (41) 41
ubiquitin-protein ligases - genetics (39) 39
ligases (38) 38
muscle atrophy (38) 38
rats (38) 38
mafbx (37) 37
expression (36) 36
muscular atrophy - pathology (33) 33
hypertrophy (32) 32
phosphorylation (32) 32
signal transduction (32) 32
article (31) 31
foxo transcription factors (31) 31
skp cullin f-box protein ligases - metabolism (31) 31
protein (29) 29
analysis (27) 27
ubiquitin-proteasome system (27) 27
activation (26) 26
autophagy (26) 26
cell line (26) 26
e3 ligase murf1 (26) 26
female (26) 26
metabolism (26) 26
mice, inbred c57bl (26) 26
in-vivo (25) 25
physiological aspects (25) 25
proteasome endopeptidase complex - metabolism (25) 25
proto-oncogene proteins c-akt - metabolism (24) 24
protein biosynthesis (23) 23
rodents (23) 23
skeletal-muscle atrophy (23) 23
ubiquitin - metabolism (23) 23
skp cullin f-box protein ligases - genetics (22) 22
muscular atrophy - genetics (21) 21
myostatin (21) 21
rna, messenger - metabolism (21) 21
denervation (20) 20
gene expression regulation (20) 20
identification (20) 20
muscle, skeletal - drug effects (20) 20
oxidative stress (20) 20
sarcopenia (20) 20
ubiquitin ligase (20) 20
kinases (19) 19
muscle fibers, skeletal - metabolism (19) 19
muscle wasting (19) 19
protein synthesis (19) 19
research (19) 19
apoptosis (17) 17
dexamethasone (17) 17
genetic aspects (17) 17
life sciences (17) 17
biophysics (16) 16
degradation (16) 16
disease models, animal (16) 16
medicine, research & experimental (16) 16
mice, knockout (16) 16
rats, sprague-dawley (16) 16
signal transduction - drug effects (16) 16
biology (15) 15
insulin (15) 15
muscle fibers, skeletal - drug effects (15) 15
muscle fibers, skeletal - pathology (15) 15
protein-synthesis (15) 15
skeletal muscle atrophy (15) 15
aging (14) 14
cachexia (14) 14
cancer cachexia (14) 14
endocrinology & metabolism (14) 14
heart (14) 14
mechanisms (14) 14
neurosciences (14) 14
signal transduction - physiology (14) 14
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (220) 220
Korean (4) 4
French (2) 2
German (2) 2
Chinese (1) 1
Japanese (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Cellular Physiology, ISSN 0021-9541, 05/2019, Volume 234, Issue 5, pp. 6194 - 6208
Skeletal muscle atrophy/wasting is associated with impaired protein metabolism in diverse physiological and pathophysiological conditions. Elevated levels of... 
atrophy | calpain | cinnamaldehyde | cathepsin | MuRF1/Atrogin1 | oxidative stress
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2019, Volume 234, Issue 5, pp. 6194 - 6208
Skeletal muscle atrophy/wasting is associated with impaired protein metabolism in diverse physiological and pathophysiological conditions. Elevated levels of... 
calpain | MuRF1/Atrogin1 | atrophy | cinnamaldehyde | cathepsin | oxidative stress
Journal Article
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 2018, Volume 28, Issue 4, p. 520
Conessine, a steroidal alkaloid, is a potent histamine H3 antagonist with antimalarial activity. We recently reported that conessine treatment interferes with... 
Conessine | atrogin-1 | MuRF1 | FoxO3a | muscle atrophy
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 07/2019, Volume 431, Issue 15, pp. 2900 - 2909
MuRF1 (TRIM63) is a RING-type E3 ubiquitin ligase with a predicted tripartite TRIM fold. TRIM proteins rely upon the correct placement of an N-terminal RING... 
coiled-coil | PELDOR | TRIM fold | disulfide cross-linking | MuRF1 | SKELETAL-MUSCLE ATROPHY | PROTEIN | DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | MOTIF | FAMILY | Ligases | Crosslinked polymers
Journal Article
FASEB Journal, ISSN 0892-6638, 11/2008, Volume 22, Issue 11, pp. 3836 - 3845
Heat shock protein 70 (Hsp70) is a highly conserved and ubiquitous protein that is reported to provide cytoprotection in various cell types and tissues.... 
Immobilization | Atrogin-1/MAFbx | MuRF1 | DISUSE ATROPHY | OXIDATIVE STRESS | ACTIVATION | immobilization | PROTEIN | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SOLEUS MUSCLE | CELL BIOLOGY | DEPENDENT PROTEOLYSIS | MESSENGER-RNA | BIOLOGY | GENE-EXPRESSION | DEGRADATION | atrogin-1/MAFbx | Research Communications | atrogin-1 | MAFbx
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 08/2019, Volume 17, Issue 1
Spaceflight or microgravity conditions cause myocardial atrophy and dysfunction, contributing to post-flight orthostatic intolerance. However, the underlying... 
Oxidases | Scientific equipment and supplies industry | Angiotensin
Journal Article
Journal of Translational Medicine, 08/2019, Volume 17, Issue 1, pp. 1 - 13
Abstract Background Spaceflight or microgravity conditions cause myocardial atrophy and dysfunction, contributing to post-flight orthostatic intolerance.... 
Losartan | MuRF1 | NADPH oxidase | Angiotensin-II | Microgravity | p47 phox phosphorylation
Journal Article
Journal Article
Journal of Cachexia, Sarcopenia and Muscle, ISSN 2190-5991, 2019
Chronic heart failure (CHF) leads to diaphragm myopathy that significantly impairs quality of life and worsens prognosis. In this study, we aimed to assess the... 
Mitochondrial metabolism | Chronic heart failure | Diaphragm | Muscle wasting | Cardiac cachexia | MuRF1
Journal Article
Molecular Therapy, ISSN 1525-0016, 03/2019, Volume 27, Issue 3, pp. 571 - 583
Our previous study showed that miR-29 attenuates muscle wasting in chronic kidney disease. Other studies found that miR-29 has anti-fibrosis activity. We... 
Yin Yang 1 | α-SMA | TGF-β1 | TRIM63/MuRF1 | TGF-β3 | FBXO32/atrogin-1 | THERAPEUTICS | MEDICINE, RESEARCH & EXPERIMENTAL | RENAL FIBROSIS | TGF-BETA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MYOGENESIS | GENETICS & HEREDITY | MICRORNAS | DELIVERY
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2009, Volume 106, Issue 29, pp. 12103 - 12108
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10263 - 8
It is known that MuRF-1 and atrogin-1/MAFbx mRNA expression is increased in rat soleus muscle under unloading conditions. We aimed to determine the role of... 
SKELETAL-MUSCLE | MURF1 | FOXO | HYPERTROPHY | PROTEIN | ATROPHY | MULTIDISCIPLINARY SCIENCES | UBIQUITIN-PROTEASOME PATHWAY | Polymerase chain reaction | Ubiquitin | Histone deacetylase | Rodents | Unloading | Event-related potentials | Gene expression | Soleus muscle | Histone acetyltransferase
Journal Article
by Wei, YH and Gong, LC and Fu, WW and Xu, SH and Wang, Z and Zhang, J and Ning, E and Chang, H and Wang, HP and Gao, YF
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 11/2018, Volume 233, Issue 11, pp. 8711 - 8722
As a typical hibernator, the Daurian ground squirrel (Spermophilus dauricus) spends considerable time in a state of reduced activity with prolonged fasting.... 
PHYSIOLOGY | ATROPHY | MuRF1 | SOLEUS MUSCLE | NF-B | hibernation | DISUSE | UBIQUITIN LIGASES | PROTEIN-SYNTHESIS | CELL BIOLOGY | disuse muscle atrophy | SKELETAL-MUSCLE | FACTOR-I IGF-1 | GENE-EXPRESSION | skeletal muscle | BIOCHEMICAL-PROPERTIES | Fasting | RNA | Proteolysis | Analysis
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, ISSN 0363-6143, 04/2014, Volume 306, Issue 8, pp. C762 - C767
The muscle-specific ring finger protein 1 (MuRF1) gene is required for most types of skeletal muscle atrophy yet we have little understanding of its... 
FoxO | CACHEXIA | PHYSIOLOGY | PROTEIN | HSP70 | MuRF1 | NF-kB | KAPPA-B | UBIQUITIN LIGASES | muscle wasting | CELL BIOLOGY | SKELETAL-MUSCLE | METABOLISM | GENE-EXPRESSION | MICE | unloading
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2009, Volume 296, Issue 6, pp. 1258 - 1270
Myostatin is a negative regulator of skeletal muscle size, previously shown to inhibit muscle cell differentiation. Myostatin requires both Smad2 and Smad3... 
MAFbx | Mammalian target of rapamycin complex signaling | MuRF1 | S6 kinase | Smad signaling | Human skeletal muscle cells | Transducer of regulated Ca | responsive element-binding protein activity | MuRF-1 | Atrogin | Transforming growth factor-β-like molecules | IGF-I | PHYSIOLOGY | ATROPHY | RAPID DISUSE | human skeletal muscle cells | transforming growth factor-beta-like molecules | SKELETAL-MUSCLE HYPERTROPHY | FOXO TRANSCRIPTION FACTORS | UBIQUITIN LIGASES | transducer of regulated Ca2+-responsive element-binding protein activity | CELL BIOLOGY | atrogin | PATHWAY | GROWTH | GENE-EXPRESSION | mammalian target of rapamycin complex signaling | CONDITIONAL ACTIVATION | Activin Receptors, Type I - antagonists & inhibitors | Protein Kinases - metabolism | Phosphorylation | Protein Kinases - genetics | Humans | Smad3 Protein - metabolism | Muscle Fibers, Skeletal - drug effects | Tripartite Motif Proteins | Smad3 Protein - genetics | Transfection | RNA Interference | Myoblasts, Skeletal - pathology | Smad2 Protein - genetics | Muscle Proteins - metabolism | Dioxoles - pharmacology | Regulatory-Associated Protein of mTOR | Benzamides - pharmacology | Myostatin - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Cell Size - drug effects | Cells, Cultured | Smad2 Protein - metabolism | Ubiquitin-Protein Ligases - metabolism | Organ Size | Activin Receptors, Type I - metabolism | Myoblasts, Skeletal - enzymology | SKP Cullin F-Box Protein Ligases - metabolism | Mice, SCID | Myostatin - antagonists & inhibitors | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Cell Differentiation - drug effects | Follistatin - pharmacology | Muscle Fibers, Skeletal - pathology | Creatine Kinase - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | TOR Serine-Threonine Kinases | Myoblasts, Skeletal - drug effects | Insulin-Like Growth Factor I - metabolism | Muscle Fibers, Skeletal - enzymology | RNA, Small Interfering - metabolism | Abdominal surgery | Musculoskeletal system | Signal transduction | Cell growth | Kinases | Gene expression | Cells | Index Medicus
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2018, Volume 233, Issue 11, pp. 8711 - 8722
We investigated the effects of hibernation inactivity on the IKKβ/NF‐κB/MuRF1 signaling pathway in different types of skeletal and cardiac muscles in Daurian... 
disuse muscle atrophy | NF‐κB | hibernation | skeletal muscle | MuRF1 | NF-κB | Ubiquitin | Cardiac muscle | Muscles | Squirrels | Gene expression | Skeletal muscle | Proteins | Atrophy | Signal transduction | Signaling | Ground squirrels | Hibernation | Arousal | Plasticity | Protein expression | Plastic properties | Ubiquitin-protein ligase
Journal Article