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mucin-5b - genetics (125) 125
mucin-5b (112) 112
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mucin-2 (25) 25
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The New England Journal of Medicine, ISSN 0028-4793, 04/2011, Volume 364, Issue 16, pp. 1503 - 1512
Journal Article
Thorax, ISSN 0040-6376, 05/2013, Volume 68, Issue 5, pp. 436 - 441
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 03/2018, Volume 58, Issue 3, pp. 299 - 309
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2012, Volume 47, Issue 2, pp. 178 - 185
Mucins are gel-forming proteins that are responsible for the characteristic viscoelastic properties of mucus. Mucin overproduction is a hallmark of asthma, but... 
Protein disulfide isomerase | Mucus | Airway epithelium | Asthma | Endoplasmic reticulum stress | AIRWAY MUCUS HYPERSECRETION | PROTEIN-DISULFIDE-ISOMERASE | protein disulfide isomerase | BIOCHEMISTRY & MOLECULAR BIOLOGY | airway epithelium | IL-4 RECEPTOR | asthma | ENDOPLASMIC-RETICULUM STRESS | endoplasmic reticulum stress | mucus | FAMILY | CELL BIOLOGY | MUC5AC MUCIN | EPITHELIAL-CELLS | RESPIRATORY SYSTEM | COLOCALIZATION | DISEASE | GENE-EXPRESSION | Asthma - metabolism | Mucoproteins - immunology | Bronchial Hyperreactivity - immunology | Mucin-5B - genetics | Humans | Endoplasmic Reticulum - metabolism | Th2 Cells - immunology | Bronchial Hyperreactivity - genetics | Allergens - administration & dosage | Inflammation - metabolism | Allergens - immunology | Mucin 5AC - immunology | Mucoproteins - biosynthesis | Respiratory Mucosa - immunology | Asthma - immunology | Hypersensitivity, Immediate - immunology | Bronchial Hyperreactivity - metabolism | Mucoproteins - genetics | Gene Expression | Mucin-5B - immunology | Hypersensitivity, Immediate - genetics | Mice, Transgenic | Inflammation - immunology | Th2 Cells - metabolism | Asthma - genetics | Proteins - immunology | Proteins - genetics | Mucin-5B - metabolism | Animals | Proteins - metabolism | Hypersensitivity, Immediate - metabolism | Endoplasmic Reticulum - immunology | Mucin 5AC - genetics | Cell Line, Tumor | Inflammation - genetics | Mucin 5AC - metabolism | Mice | Respiratory Mucosa - metabolism | Mucin 5AC - biosynthesis | Mucin-5B - biosynthesis | Mucoproteins - metabolism
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 3, pp. 799 - 810.e7
Background Balanced activation and inhibition of the immune system ensures pathogen clearance while avoiding hyperinflammation. Siglecs, sialic acid–binding... 
Allergy and Immunology | Chronic rhinosinusitis | nuclear factor κB | inflammation | submucosal gland cells | siglecs | glycobiology | mucin 5B | F LIGANDS | ACTIVATION | PROTEIN | RECOGNITION | nuclear factor kappa B | GLYCANS | IMMUNOLOGY | ALLERGY | DEFICIENT | SECRETION | RECEPTORS | Antigens, CD - immunology | RNA, Small Interfering - genetics | Respiratory Mucosa - drug effects | Mucin-5B - genetics | Epithelial Cells - drug effects | Humans | Middle Aged | NF-kappa B - immunology | Male | Antigens, CD - genetics | Lipopolysaccharides | Respiratory Mucosa - pathology | Sialic Acid Binding Immunoglobulin-like Lectins - immunology | Sinusitis - genetics | Sinusitis - immunology | Respiratory Mucosa - immunology | Antigens, Differentiation, B-Lymphocyte - immunology | Sinusitis - pathology | Adult | Female | Mucin-5B - antagonists & inhibitors | Antigens, Differentiation, B-Lymphocyte - genetics | Cell Line | Rhinitis - immunology | Lectins - immunology | Mucin-5B - immunology | Signal Transduction | Gene Expression Regulation | Epithelial Cells - pathology | Tumor Necrosis Factor-alpha | Sialic Acid Binding Immunoglobulin-like Lectins - genetics | Rhinitis - genetics | NF-kappa B - genetics | Epithelial Cells - immunology | Lectins - genetics | Ligands | Primary Cell Culture | Rhinitis - pathology | Chronic Disease | RNA, Small Interfering - metabolism | Binding proteins | Organic acids | Protein binding | Proteins | Sinuses | Plasmids | Laboratories | Otolaryngology | Phosphatase | Immune system | NF-κB | chronic rhinosinusitis | MUC5B
Journal Article
Veterinary Microbiology, ISSN 0378-1135, 03/2013, Volume 162, Issue 2-4, pp. 456 - 470
Cyprinid herpesvirus-3 (CyHV-3) is recognised as a pathogen which causes mass mortality in populations of carp, . One of the characteristic symptoms of the... 
Claudins | Cyprinid herpesvirus 3 | Antimicrobial peptides | Mucins | Interferon | Inflammation | Bacterial flora | Skin infection | MICROBIOLOGY | FUNCTIONAL-CHARACTERIZATION | EPITHELIAL-CELLS | TELEOST FISH | GENE-EXPRESSION | KOI HERPESVIRUS | VETERINARY SCIENCES | TIGHT JUNCTION PROTEINS | ATLANTIC SALMON | APOLIPOPROTEIN-A-I | INNATE IMMUNITY | Up-Regulation | Epithelial Cells - metabolism | Skin - microbiology | Mucin-5B - genetics | Skin - metabolism | Antimicrobial Cationic Peptides - biosynthesis | Claudins - biosynthesis | Herpesviridae Infections - veterinary | Interleukin-1beta - genetics | Antimicrobial Cationic Peptides - metabolism | Herpesviridae Infections - pathology | Interferon Type I - biosynthesis | Claudins - metabolism | Interleukin-1beta - metabolism | Herpesviridae Infections - metabolism | Interferon Type I - metabolism | RNA, Bacterial - genetics | Antimicrobial Cationic Peptides - genetics | Skin - virology | Skin - pathology | Claudins - genetics | Goblet Cells - virology | Carps | Skin Diseases, Viral - metabolism | Skin Diseases, Viral - virology | Herpesviridae Infections - virology | Fish Diseases - genetics | Fish Diseases - pathology | Mucin-5B - metabolism | Animals | Fish Diseases - virology | RNA, Ribosomal, 16S - biosynthesis | Nitric Oxide Synthase Type II - genetics | Virus Replication | RNA, Bacterial - biosynthesis | Epithelial Cells - virology | Herpesviridae - physiology | Skin Diseases, Viral - pathology | Interferon Type I - genetics | RNA, Ribosomal, 16S - genetics | Skin Diseases, Viral - veterinary | Mucin-5B - biosynthesis | Fish Diseases - metabolism | Goblet Cells - cytology | Nitric Oxide Synthase Type II - metabolism | Bacterial infections | Peptides | Genes | Development and progression | Disease susceptibility | Biological response modifiers | Risk factors | Virus diseases | Messenger RNA | Fishes | Skin | Universities and colleges | Health aspects
Journal Article
by Juge, Pierre-Antoine and Lee, Joyce S and Ebstein, Esther and Furukawa, Hiroshi and Dobrinskikh, Evgenia and Gazal, Steven and Kannengiesser, Caroline and Ottaviani, Sébastien and Oka, Shomi and Tohma, Shigeto and Tsuchiya, Naoyuki and Rojas-Serrano, Jorge and González-Pérez, Montserrat I and Mejía, Mayra and Buendía-Roldán, Ivette and Falfán-Valencia, Ramcés and Ambrocio-Ortiz, Enrique and Manali, Effrosyni and Papiris, Spyros A and Karageorgas, Theofanis and Boumpas, Dimitrios and Antoniou, Katarina and van Moorsel, Coline H.M and van der Vis, Joanne and de Man, Yaël A and Grutters, Jan C and Wang, Yaping and Borie, Raphaël and Wemeau-Stervinou, Lidwine and Wallaert, Benoît and Flipo, René-Marc and Nunes, Hilario and Valeyre, Dominique and Saidenberg-Kermanac’h, Nathalie and Boissier, Marie-Christophe and Marchand-Adam, Sylvain and Frazier, Aline and Richette, Pascal and Allanore, Yannick and Sibilia, Jean and Dromer, Claire and Richez, Christophe and Schaeverbeke, Thierry and Lioté, Huguette and Thabut, Gabriel and Nathan, Nadia and Amselem, Serge and Soubrier, Martin and Cottin, Vincent and Clément, Annick and Deane, Kevin and Walts, Avram D and Fingerlin, Tasha and Fischer, Aryeh and Ryu, Jay H and Matteson, Eric L and Niewold, Timothy B and Assayag, Deborah and Gross, Andrew and Wolters, Paul and Schwarz, Marvin I and Holers, Michael and Solomon, Joshua J and Doyle, Tracy and Rosas, Ivan O and Blauwendraat, Cornelis and Nalls, Mike A and Debray, Marie-Pierre and Boileau, Catherine and Crestani, Bruno and Schwartz, David A and Dieudé, Philippe
The New England Journal of Medicine, ISSN 0028-4793, 12/2018, Volume 379, Issue 23, pp. 2209 - 2219
In this study, a gain-of-function variant in the promoter of MUC5B that was previously found to be associated with idiopathic pulmonary fibrosis was associated... 
MORTALITY | CRITERIA | MEDICINE, GENERAL & INTERNAL | PREDICTORS | SUSCEPTIBILITY | CLASSIFICATION | COHORT | POLYMORPHISM | IDIOPATHIC PULMONARY-FIBROSIS | PNEUMONIA | ASSOCIATION | Genetic aspects | Pulmonary fibrosis | Diagnosis | Research | Rheumatoid arthritis | Consortia | Pneumonia | Computed tomography | Lung diseases | Rheumatology | Fibrosis | Population | Health risk assessment | Population genetics
Journal Article