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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2015, Volume 35, Issue 12, pp. 2605 - 2616
OBJECTIVE—Kawasaki disease (KD) is the most common cause of acute vasculitis and acquired cardiac disease among US children. We have previously shown that both... 
dendritic cells | interleukin-1 | mucocutaneous lymph node syndrome | MyD88 | Endothelial cells | protein | endothelial cells | ELEMENT-BINDING PROTEIN-2 | ACTIVATION | RECEPTOR | CORONARY-ARTERY ANEURYSMS | NLRP3 INFLAMMASOME | POLYMORPHISM | ACUTE-PHASE | INTRAVENOUS IMMUNOGLOBULIN | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ASSOCIATION | Lactobacillus casei | Mucocutaneous Lymph Node Syndrome - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Stromal Cells - pathology | Caspase 1 - metabolism | Interleukin-1alpha - metabolism | Aortitis - chemically induced | Aorta - metabolism | Coronary Vessels - metabolism | Cell Wall | DNA-Binding Proteins - metabolism | Receptors, Interleukin-1 Type I - metabolism | Interleukin-1beta - metabolism | Bone Marrow Transplantation | Coronary Artery Disease - pathology | Aortitis - pathology | Dendritic Cells - metabolism | Disease Models, Animal | Mucocutaneous Lymph Node Syndrome - pathology | Coronary Vessels - pathology | Signal Transduction | Coronary Artery Disease - chemically induced | Endothelial Cells - metabolism | Mucocutaneous Lymph Node Syndrome - chemically induced | Coronary Artery Disease - metabolism | Mice, Inbred C57BL | Stromal Cells - metabolism | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Aortitis - genetics | DNA-Binding Proteins - genetics | Transplantation Chimera | Mice, Knockout | Aorta - pathology | Mucocutaneous Lymph Node Syndrome - genetics | Aortitis - metabolism | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Coronary Artery Disease - genetics | Receptors, Interleukin-1 Type I - genetics | Myeloid Differentiation Factor 88 - metabolism | Bone Marrow Cells - metabolism | coronary artery vasculitis | Kawasaki disease | IL-1
Journal Article
PLOS MEDICINE, ISSN 1549-1277, 07/2019, Volume 16, Issue 7, p. e1002844
Background Kawasaki disease is an acute vasculitis that primarily affects children younger than 5 years of age. Its etiology is unknown. The United States... 
STATEMENT | LONG-TERM MANAGEMENT | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | HEALTH-PROFESSIONALS | COMMITTEE | United States - epidemiology | Age Factors | Risk Assessment | Adverse Drug Reaction Reporting Systems | Mucocutaneous Lymph Node Syndrome - chemically induced | Humans | Risk Factors | Infant | Male | Pneumococcal Vaccines - administration & dosage | Vaccination - adverse effects | Mucocutaneous Lymph Node Syndrome - epidemiology | Time Factors | Patient Safety | Female | Immunization Schedule | Pneumococcal Vaccines - adverse effects | Mucocutaneous Lymph Node Syndrome - diagnosis | Infant, Newborn | United States Food and Drug Administration | Dosage and administration | Kawasaki disease | Demographic aspects | Pneumococcal vaccine | Patient outcomes | Risk factors | Vaccination of children | Vaccination | Medical records | Development and progression | Research | Children | Intervals | Conjugates | Regulatory agencies | Control methods | Population studies | Vaccines | Medical schools | Streptococcus infections | Vasculitis | Etiology | Safety engineering | Classification | Control charts | Population | Safety | Drug dosages | Supervision | Age | Food | Medical personnel | Immunization | Enrollments | Health care policy | Health risks | Disease control | Investigations | Medicine | Disease prevention | Health maintenance organizations--HMOs | Surveillance | Software | Mucocutaneous lymph node syndrome | Risk management | Health maintenance organizations | HMOs
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, p. e0144603
Background Kawasaki disease (KD) is also known as multiple mucocutaneous lymph node syndrome of systemic vasculitis and is a leading cause of coronary artery... 
LONG-TERM MANAGEMENT | DIAGNOSIS | CORONARY-ARTERY LESIONS | INTRAVENOUS IMMUNOGLOBULIN | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN TREATMENT FAILURE | CARDIOVASCULAR-DISEASE | RESISTANCE | HEALTH-PROFESSIONALS | ENDOCARDITIS | RHEUMATIC-FEVER | Mucocutaneous Lymph Node Syndrome - drug therapy | Humans | Anemia - chemically induced | Child, Preschool | Hepcidins - blood | Male | Treatment Outcome | Dose-Response Relationship, Drug | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Immunoglobulins, Intravenous - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Aspirin - adverse effects | Female | Aspirin - therapeutic use | Leukocyte Count | Retrospective Studies | C-Reactive Protein - analysis | Drug Therapy, Combination | Child | Hemoglobins - analysis | Immunologic Factors - therapeutic use | Mucocutaneous Lymph Node Syndrome - blood | Complications and side effects | Aspirin | Kawasaki disease | Anemia | Patient outcomes | Dosage and administration | Research | Drug therapy | Risk factors | Pediatrics | Intravenous administration | Bleeding | Vasculitis | Hemoglobin | Gallbladder | Children | Lesions | Systemic vasculitis | Drug dosages | Immunoglobulins | Coronary artery | Data processing | Inflammation | Health care facilities | Patients | Fever | White blood cells | Medicine | Hospitals | Coronary vessels | Mucocutaneous lymph node syndrome | Hepcidin | Veins & arteries | Medical services
Journal Article
Journal of Vascular Research, ISSN 1018-1172, 01/2017, Volume 53, Issue 5-6, pp. 340 - 348
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2016, Volume 36, Issue 5, pp. 886 - 897
OBJECTIVE—Kawasaki disease (KD) is the most common cause of acquired cardiac disease in US children. In addition to coronary artery abnormalities and... 
vasculitis | caspase-1 | abdominal aortic aneurysm | aortitis | dilatation | CORONARY ARTERITIS | IL-1 | INFLAMMASOME ACTIVATION | NLRP3 INFLAMMASOME | CHILDREN | IL-1-ALPHA | INTRAVENOUS IMMUNOGLOBULIN | PERIPHERAL VASCULAR DISEASE | MACROPHAGE ELASTASE | IL-1-BETA | HEMATOLOGY | INSIGHTS | Aortic Aneurysm, Abdominal - prevention & control | Cell Proliferation | Humans | Male | Gene Expression Profiling | Interleukin-1beta - genetics | Aorta, Abdominal - drug effects | Interleukin-1beta - deficiency | Aortic Aneurysm, Abdominal - metabolism | Time Factors | Interleukin-1beta - metabolism | Interleukin-1alpha - genetics | Interleukin 1 Receptor Antagonist Protein - pharmacology | Aortitis - pathology | Dilatation, Pathologic | Disease Models, Animal | Macrophages - pathology | Mucocutaneous Lymph Node Syndrome - chemically induced | Genotype | Mice, Knockout | Aortitis - metabolism | Macrophages - metabolism | Phenotype | Signal Transduction - drug effects | Caspase 1 - deficiency | Interleukin-1alpha - deficiency | Lactobacillus casei | Muscle, Smooth, Vascular - metabolism | Myocytes, Smooth Muscle - pathology | Interleukin-1alpha - metabolism | Cell Wall | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Receptors, Interleukin-1 Type I - metabolism | Mucocutaneous Lymph Node Syndrome - complications | Female | Aorta, Abdominal - pathology | Aorta, Abdominal - metabolism | Myocytes, Smooth Muscle - metabolism | Aortic Aneurysm, Abdominal - pathology | Receptors, Interleukin-1 Type I - deficiency | Elastin - metabolism | Mucocutaneous Lymph Node Syndrome - drug therapy | Mice, Inbred C57BL | Aortitis - genetics | Aortic Aneurysm, Abdominal - genetics | NLR Family, Pyrin Domain-Containing 3 Protein - deficiency | Muscle, Smooth, Vascular - pathology | Animals | Caspase 1 - genetics | Receptors, Interleukin-1 Type I - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, p. e38635
Background: Kawasaki disease (KD) of unknown immunopathogenesis is an acute febrile systemic vasculitis and the leading cause of acquired heart diseases in... 
IMMUNOGLOBULIN TREATMENT | GAMMA-GLOBULIN TREATMENT | LYMPH-NODE SYNDROME | SYSTEMIC INJECTION | BIOLOGY | AQUEOUS SUSPENSION | ANIMAL-MODEL | TRANSCRIPTIONAL REGULATION | LESIONS | CASEI CELL-WALLS | TREATMENT FAILURE | gamma-Globulins - administration & dosage | Toll-Like Receptor 2 - genetics | Mucocutaneous Lymph Node Syndrome - metabolism | Coronary Artery Disease - chemically induced | Humans | Gene Expression Regulation | Child, Preschool | Infant | Male | Monocytes - metabolism | Toll-Like Receptor 2 - biosynthesis | Lipopolysaccharide Receptors - metabolism | Mucocutaneous Lymph Node Syndrome - genetics | Animals | Cell Wall - metabolism | Myocardium - metabolism | Coronary Artery Disease - genetics | Lactobacillus casei - metabolism | Female | Mice | Mice, Inbred BALB C | Disease Models, Animal | Prevention | Interleukins | Analysis | Children | Heart diseases | Histochemistry | Diseases | Pediatrics | Intravenous administration | Aneurysms | CD14 antigen | Arteritis | Proteins | Cell activation | Histopathology | Immunopathogenesis | Bioindicators | Systemic vasculitis | Drug dosages | Gamma globulin | Pericarditis | Medical research | Immunoglobulins | Echocardiography | Cytokines | Abnormalities | Patients | Augmentation | Studies | Pathology | Hospitals | Monocyte chemoattractant protein | TLR2 protein | Interleukin 10 | Plasma levels | Cardiovascular diseases | Interleukin | Arthritis | Interleukin 6 | Kawasaki disease | Vasculitis | Toll-like receptors | Immune system | Immune response | Cell walls | Lactobacilli | Inflammation | Coronary artery disease | Medicine | Myocarditis | Monocytes | Globulins | Coronary vessels | Mucocutaneous lymph node syndrome | Veins & arteries
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 22, pp. 2578 - 2583
Journal Article
Endocrine Journal, ISSN 0918-8959, 2014, Volume 62, Issue 2, pp. 145 - 151
Combination treatment with intravenous immunoglobulin (IVIG) plus prednisolone, newly designed for children with severe Kawasaki disease (KD), reduces coronary... 
Kawasaki disease | CRH stimulation test | Adrenal suppression | Prednisolone | CORTICOTROPIN-RELEASING HORMONE | LONG-TERM | MORTALITY | DEXAMETHASONE | RECOVERY | ACUTE LYMPHOBLASTIC-LEUKEMIA | GROWTH | ENDOCRINOLOGY & METABOLISM | SHORT-TERM | DOSE GLUCOCORTICOID THERAPY | AXIS | Adrenocorticotropic Hormone - antagonists & inhibitors | Japan - epidemiology | Prednisolone - adverse effects | Glucocorticoids - therapeutic use | Prospective Studies | Adrenal Insufficiency - epidemiology | Humans | Hydrocortisone - secretion | Immunoglobulins, Intravenous - adverse effects | Child, Preschool | Hydrocortisone - therapeutic use | Infant | Male | Risk | Incidence | Anti-Inflammatory Agents - adverse effects | Anti-Inflammatory Agents - therapeutic use | Female | Adrenal Glands - secretion | Prednisolone - therapeutic use | Adrenal Glands - drug effects | Hydrocortisone - blood | Child | Adrenocorticotropic Hormone - blood | Glucocorticoids - adverse effects | Mucocutaneous Lymph Node Syndrome - blood | Pituitary-Adrenal System - secretion | Pituitary-Adrenal System - physiopathology | Mucocutaneous Lymph Node Syndrome - drug therapy | Mucocutaneous Lymph Node Syndrome - physiopathology | Pituitary-Adrenal System - drug effects | Mucocutaneous Lymph Node Syndrome - therapy | Adrenal Insufficiency - prevention & control | Combined Modality Therapy - adverse effects | Adrenocorticotropic Hormone - secretion | Hydrocortisone - adverse effects | Immunoglobulins, Intravenous - therapeutic use | Adrenal Glands - physiopathology | Adrenal Insufficiency - chemically induced | Hydrocortisone - antagonists & inhibitors
Journal Article
Pediatric Infectious Disease Journal, ISSN 0891-3668, 05/2010, Volume 29, Issue 5, pp. 430 - 433
Journal Article