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Nature Immunology, ISSN 1529-2908, 03/2017, Volume 18, Issue 4, pp. 402 - 411
Journal Article
PLoS Biology, ISSN 1544-9173, 06/2017, Volume 15, Issue 6, p. e2001930
Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and Streptococcus pyogenes. They target a large fraction of T cell pools to set in... 
NKT CELLS | INVARIANT T-CELLS | GAMMA PRODUCTION | STAPHYLOCOCCAL-ENTEROTOXIN-B | ALPHA-CHAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | TOXIC-SHOCK-SYNDROME | BINDING | MR1 | MHC CLASS-II | CD1D-INDEPENDENT ACTIVATION | Superantigens - toxicity | Leukocytes, Mononuclear - metabolism | Enterotoxins - secretion | Enterotoxins - toxicity | Transplantation Chimera - immunology | Humans | Superantigens - metabolism | Mucosal-Associated Invariant T Cells - immunology | Mucosal-Associated Invariant T Cells - metabolism | Clonal Anergy - drug effects | Bone Marrow Cells - immunology | Leukocytes, Mononuclear - immunology | Bone Marrow Cells - drug effects | Female | Mucosal-Associated Invariant T Cells - cytology | Antigens, Bacterial - toxicity | Staphylococcus aureus - metabolism | Cell Line | Mucosal-Associated Invariant T Cells - drug effects | Leukocytes, Mononuclear - drug effects | Specific Pathogen-Free Organisms | Bone Marrow Cells - cytology | Streptococcus pyogenes - immunology | Cells, Cultured | Mice, Transgenic | Streptococcus pyogenes - metabolism | Immunity, Innate | Mice, SCID | Mice, Knockout | Transplantation Chimera - metabolism | Models, Immunological | Animals | Transplantation Chimera - blood | Lymphocyte Activation - drug effects | Hybridomas | Leukocytes, Mononuclear - cytology | Mice, Inbred NOD | Staphylococcus aureus - immunology | Mice | Antigens, Bacterial - metabolism | Bone Marrow Cells - metabolism | Crosses, Genetic | Klebsiella | Anergy | Mucosa | Colleges & universities | Antiinfectives and antibacterials | Invariants | Proteins | T-cell receptor | Genotype & phenotype | Signal transduction | Cell activation | Illnesses | Surgery | Bone marrow | Medical research | Cytokines | Enterotoxin B | Interleukin 12 | T cell receptors | Roles | Pools | Gene expression | Interleukin 18 | Immunosuppression | Major histocompatibility complex | Sag | Sepsis | Affinity | Animal models | Pneumonia | Interleukin | Editing | Lymphocytes T | Infections | Activation | CD223 antigen | Kinases | Immunology | E coli | Lymphocytes | Bacteria | Tumor necrosis factor-TNF | Chimeras | Bacterial infections | Transgenic mice | Inflammation | Streptococcus | Exotoxins | Cell death | Exhaustion | Writing | Interferon | Histocompatibility antigen HLA | Apoptosis
Journal Article
Gastroenterology, ISSN 0016-5085, 11/2017, Volume 153, Issue 5, pp. 1392 - 1403.e2
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0159243
textabstractObjective Mucosal-associated invariant T (MAIT) cells comprise a subpopulation of T cells that can be activated by bacterial products and cytokines... 
RESPONSES | INVARIANT T-CELLS | INTERFERON | ACTIVATION | NK CELLS | ROLES | MULTIDISCIPLINARY SCIENCES | INFECTION | INDUCTION | HEPATITIS-C | EXHAUSTION | Mucosal-Associated Invariant T Cells - drug effects | Antiviral Agents - therapeutic use | Coinfection - drug therapy | Coinfection - immunology | Humans | Middle Aged | Male | Hepatitis C, Chronic - complications | Interferon-gamma - metabolism | Hepatitis C, Chronic - drug therapy | Coinfection - virology | Case-Control Studies | Killer Cells, Natural - physiology | HIV Infections - immunology | Flow Cytometry | HIV Infections - complications | Hepatitis C, Chronic - immunology | Lymphocyte Count | Adult | Anti-HIV Agents - therapeutic use | HIV Infections - drug therapy | Aged | Mucosal-Associated Invariant T Cells - physiology | Physiological aspects | Development and progression | Genetic aspects | Research | Hepatitis C | T cells | HIV infection | Therapy | Phenotypes | Bacterial infections | Cytokines | Internal medicine | Mucosa | Chronic infection | Infections | Lymphocytes T | T cell receptors | Patients | Blood | α-Interferon | Hepatitis | Infectious diseases | Immunology | Lymphocytes | CD38 antigen | Hepatology | Human immunodeficiency virus--HIV | γ-Interferon | Gastroenterology | Sampling methods | Interferon | HIV | Human immunodeficiency virus
Journal Article
PLOS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0171139
Silymarin (SM), and its flavonolignan components, alter cellular metabolism and inhibit inflammatory status in human liver and T cell lines. In this study, we... 
INVARIANT T-CELLS | IN-VITRO | VIRUS-INFECTION | MULTIDISCIPLINARY SCIENCES | HIV-INFECTED INDIVIDUALS | CHRONIC HEPATITIS-C | ANTIRETROVIRAL THERAPY | CHRONIC VIRAL-INFECTION | MICROBIAL TRANSLOCATION | HCV INFECTION | DISEASE PROGRESSION | Biomarkers - metabolism | Leukocytes, Mononuclear - metabolism | Mucosal-Associated Invariant T Cells - drug effects | Leukocytes, Mononuclear - drug effects | Pathogen-Associated Molecular Pattern Molecules - metabolism | Receptors, Antigen, T-Cell - metabolism | Humans | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | HIV Infections - immunology | Inflammation - metabolism | Mucosal-Associated Invariant T Cells - metabolism | Flow Cytometry | Lymphocyte Activation - drug effects | T-Lymphocyte Subsets - drug effects | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | CD8-Positive T-Lymphocytes - metabolism | Silymarin - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Inflammation | Milk thistle | Research | T cells | HIV infection | CD8 antigen | Liver | Mucosa | Chronic infection | Activation | Lymphocytes T | T-cell receptor | Cell activation | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Immune system | Immunological memory | Cytokines | Immunoregulation | Markers | T cell receptors | Metabolism | CD4 antigen | Monocytes | Silymarin | Hepatocytes | Exhaustion | Cell lines | Stem cells | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Clinical and Experimental Medicine, ISSN 1591-8890, 11/2016, Volume 16, Issue 4, pp. 529 - 537
Immune reconstitution after high-dose chemotherapy and stem cell transplantation plays a key role in restoring immunocompetence including defense against... 
Autologous peripheral blood stem cell transplantation | Medicine & Public Health | Hematology | Complications | Myeloablative chemotherapy | MAIT cells | Internal Medicine | Oncology | Recovery | MEDICINE, RESEARCH & EXPERIMENTAL | CD8(+) | DEFINES | MR1 | SUBSET | AGE | Hematologic Neoplasms - therapy | Myeloablative Agonists - pharmacology | Podophyllotoxin - pharmacology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Cytarabine - pharmacology | Age Factors | Peripheral Blood Stem Cell Transplantation - methods | Humans | Middle Aged | Male | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Mucosal-Associated Invariant T Cells - metabolism | C-Reactive Protein - metabolism | Podophyllotoxin - administration & dosage | Female | Melphalan - pharmacology | Transplantation Conditioning - methods | Mucosal-Associated Invariant T Cells - drug effects | Carmustine - pharmacology | Transplantation, Autologous - methods | Cytarabine - administration & dosage | Melphalan - administration & dosage | Hematologic Neoplasms - blood | Myeloablative Agonists - administration & dosage | Hematologic Neoplasms - immunology | Carmustine - administration & dosage | Chemotherapy | Transplantation | T cells | Hematopoietic stem cells | Stem cells | Cancer | Transplants & implants | Cellular biology | Lymphocytes
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 11/2017, Volume 102, Issue 5, pp. 1261 - 1269
Human MAIT cells have the capacity to provide help to B cells through induction of plasmablast differentiation and antibody production. Mucosal‐associated... 
B cell help | plasmablast | antibody | MR‐1 | Plasmablast | Antibody | MR-1 | GAMMA | ACTIVATION | RECEPTOR HETEROGENEITY | MECHANISM | INNATE | PROLIFERATION | ANTIGENS | IMMUNOLOGY | MR1 | CELL BIOLOGY | IMMUNE-RESPONSES | HEMATOLOGY | Cell Communication - immunology | Formaldehyde - chemistry | Immunoglobulin A - biosynthesis | Coculture Techniques | Escherichia coli - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Immunity, Mucosal | Mucosal-Associated Invariant T Cells - immunology | Interleukins - genetics | Immunoglobulin G - biosynthesis | Interleukins - immunology | Minor Histocompatibility Antigens - genetics | Tumor Necrosis Factor-alpha - immunology | Interferon-gamma - genetics | Mucosal-Associated Invariant T Cells - cytology | Formaldehyde - toxicity | Minor Histocompatibility Antigens - immunology | B-Lymphocytes - cytology | Gene Expression | Interleukin-6 - genetics | Signal Transduction | Cell Separation | Gene Expression Regulation - immunology | Lymphocyte Activation | Histocompatibility Antigens Class I - immunology | Escherichia coli - immunology | Histocompatibility Antigens Class I - genetics | Escherichia coli - chemistry | B-Lymphocytes - immunology | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukin-6 - immunology | Polymers - toxicity | Immunologic Memory | Polymers - chemistry | Primary Cell Culture | Interleukin-10 - immunology | Immunoglobulin M - biosynthesis | Lymphocyte receptors | Immunoglobulin M | Memory cells | Immunological memory | Cytokines | Immunoglobulin G | Mucosa | Lymphocytes T | Immunoglobulin A | Invariants | Interleukin 6 | Major histocompatibility complex | Lymphocytes B | Differentiation | Host Defense & Pathophysiology
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0161786
Journal Article
Liver International, ISSN 1478-3223, 03/2018, Volume 38, Issue 3, pp. 458 - 468
Journal Article