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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 13097 - 13102
Skin homeostasis is critical to preserve animal integrity. Although the skin of most vertebrates is known to contain a skin-associated lymphoid tissue (SALT),... 
Immunoglobulins | Microbiota | B lymphocytes | Antibodies | Bacteria | Skin | Mucus | Infections | Parasites | Mammals | Evolution | Ichthyophthirius multifiliis | Cutaneous | Mucosal immunoglobulin | cutaneous | COLLECTION | IGA | RAINBOW-TROUT | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | mucosal immunoglobulin | evolution | IDENTIFICATION | DERMATOLOGY | B-CELLS | IMMUNOGLOBULIN-A | LYMPHOID-TISSUE | FISH | Immunity, Mucosal - immunology | Skin - microbiology | Immunoglobulins - immunology | Mucous Membrane - parasitology | Immunoglobulin M - immunology | Fish Diseases - parasitology | Host-Pathogen Interactions - immunology | Lymphoid Tissue - immunology | Hymenostomatida - immunology | Epidermis - parasitology | Gastrointestinal Tract - immunology | Bacteria - immunology | Flow Cytometry | Oncorhynchus mykiss - microbiology | Epidermis - microbiology | Immunoglobulins - blood | Fish Diseases - immunology | B-Lymphocyte Subsets - immunology | Oncorhynchus mykiss - immunology | Oncorhynchus mykiss - parasitology | Skin - immunology | Fish Diseases - microbiology | Skin - parasitology | Host-Parasite Interactions - immunology | Blotting, Western | Animals | B-Lymphocytes - immunology | Immunoglobulin M - blood | Epidermis - immunology | Mucous Membrane - immunology | Hymenostomatida - physiology | Microscopy, Fluorescence | Mucous Membrane - microbiology | Physiological aspects | Homeostasis | Immune response | Research | Teleostei | Biological Sciences
Journal Article
Immunological Reviews, ISSN 0105-2896, 07/2011, Volume 242, Issue 1, pp. 205 - 219
The adoption of the concept that asthma is primarily a disease most frequently associated with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the... 
remodeling | environmental injury | phenotypes | inflammation | origins | progression | asthma | epithelium | Progression | Origins | Phenotypes | Environmental injury | Inflammation | Epithelium | Remodeling | Asthma | RETICULAR BASEMENT-MEMBRANE | CHEMOKINE RECEPTOR 4 | DENDRITIC CELLS | INCREASED EXPRESSION | IMMUNOLOGY | CHILDHOOD ASTHMA | THYMIC STROMAL LYMPHOPOIETIN | TIGHT JUNCTIONS | EPIDERMAL-GROWTH-FACTOR | GOBLET CELL HYPERPLASIA | BRONCHIAL-ASTHMA | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | Hypersensitivity - immunology | Infant | Th2 Cells - immunology | Rhinovirus - physiology | Hypersensitivity - drug therapy | Airway Remodeling - immunology | Picornaviridae Infections - virology | Epithelium - immunology | Signal Transduction - immunology | Allergens - immunology | Asthma - immunology | Anti-Inflammatory Agents - therapeutic use | Adult | Respiratory Tract Infections - virology | Rhinovirus - immunology | Child | Respiratory System - immunology | Cytokines - immunology | Adaptive Immunity | Epithelium - drug effects | Picornaviridae Infections - immunology | Asthma - physiopathology | Epithelium - metabolism | Inflammation - immunology | Immunity, Innate | Asthma - drug therapy | Th2 Cells - metabolism | Mice, Knockout | Animals | Hypersensitivity - physiopathology | Epithelial Cells - immunology | Respiratory System - drug effects | Respiratory Tract Infections - immunology | Respiratory System - physiopathology | Mice | Mucus - immunology | Allergens | Allergy | Dendritic cells | Asthma in children | Development and progression | Disease susceptibility | Health aspects | Allergic reaction | Hypersensitivity | Helper cells | Lymphocytes T | Atopy | Respiratory tract | Bronchoconstriction | Respiratory tract diseases | Microenvironments | Children | Pollutants | Growth factors | Adoption
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2002, Volume 169, Issue 1, pp. 443 - 453
We have biologically characterized two new members of the IL-17 cytokine family: IL-17F and IL-25. In contrast to conventional in vitro screening approaches,... 
RECEPTOR-GAMMA CHAIN | LYMPHOID DEVELOPMENT | ANTIBODY | ASTHMA | GENE-THERAPY | AIRWAY HYPERRESPONSIVENESS | DEFICIENT MICE | IMMUNOLOGY | IDENTIFICATION | CELL | EXPRESSION | Interleukin-13 - physiology | Bronchial Hyperreactivity - immunology | Humans | Pulmonary Eosinophilia - genetics | Pulmonary Eosinophilia - virology | Interleukin-17 - physiology | Male | Th2 Cells - immunology | Lymphocyte Subsets - immunology | Leukocytosis - virology | Cell Movement - immunology | Th1 Cells - metabolism | RNA, Messenger - biosynthesis | Growth Substances - genetics | Interleukins | Adenoviridae - immunology | Growth Substances - administration & dosage | Amino Acid Sequence | Leukocytosis - immunology | Interleukin-17 - genetics | Neutrophils - virology | Intestinal Diseases, Parasitic - immunology | Mice, Knockout | Mice | Mice, Inbred BALB C | Amino Acid Motifs - genetics | Strongylida Infections - genetics | Molecular Sequence Data | Interleukin-5 - biosynthesis | Th1 Cells - immunology | Hematopoietic Stem Cells - immunology | Interleukin-17 - chemistry | Intestinal Diseases, Parasitic - genetics | Growth Substances - chemistry | Strongylida Infections - immunology | Basophils - immunology | Adenoviridae - genetics | Killer Cells, Natural - immunology | Female | Mucus - metabolism | Interleukin-5 - physiology | Lung - metabolism | Pulmonary Eosinophilia - immunology | Mast Cells - immunology | Lung - pathology | Mice, Inbred C57BL | Aspergillosis - genetics | Neutrophils - immunology | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Interleukin-17 - biosynthesis | Administration, Intranasal | Th2 Cells - metabolism | Sequence Homology, Amino Acid | Animals | Amino Acid Motifs - immunology | Growth Substances - physiology | Inflammation - genetics | Genetic Vectors | Leukocytosis - genetics | Granulocytes - immunology | Lung - immunology | Aspergillosis - immunology
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 2011, Volume 35, Issue 12, pp. 1388 - 1399
Protein–carbohydrate interactions mediated by lectins have been recognized as key components of innate immunity in vertebrates and invertebrates, not only for... 
Self/non-self recognition | Regulatory functions | Complement activation | Lectins | Innate immunity | Fish | Effector | SKIN MUCUS | BASS MORONE-SAXATILIS | C-TYPE LECTIN | ZEBRAFISH DANIO-RERIO | IMMUNOLOGY | CATFISH ICTALURUS-PUNCTATUS | PENTRAXIN-LIKE PROTEIN | CARP CYPRINUS-CARPIO | ZOOLOGY | RHAMNOSE-BINDING LECTIN | F-TYPE LECTIN | TROUT ONCORHYNCHUS-MYKISS | Antigens, Viral - metabolism | Vertebrates - immunology | Antigens, Bacterial - immunology | Complement System Proteins - immunology | Complement Activation - immunology | Fishes - immunology | Opsonin Proteins - genetics | Fish Proteins - genetics | Lectins - metabolism | Bacteria - immunology | Antifreeze Proteins - immunology | Protein Structure, Quaternary | Lectins - chemistry | Adaptive Immunity | Protein Structure, Tertiary | Opsonin Proteins - immunology | Fish Proteins - chemistry | Fish Proteins - immunology | Lectins - immunology | Gene Expression Regulation - immunology | Phagocytosis - immunology | Fish Proteins - metabolism | Models, Molecular | Viruses - immunology | Immunity, Innate | Organ Specificity | Fish Proteins - classification | Lectins - classification | Antifreeze Proteins - genetics | Antigens, Viral - immunology | Animals | Invertebrates - immunology | Lectins - genetics | Antigens, Bacterial - metabolism | Analysis | non-self recognition | Self
Journal Article
Journal Article
Molecular Immunology, ISSN 0161-5890, 12/2013, Volume 56, Issue 4, pp. 317 - 327
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 2, pp. 429 - 439.e8
Background Early-life human rhinovirus infection has been linked to asthma development in high-risk infants and children. Nevertheless, the role of rhinovirus... 
Allergy and Immunology | neonatal | mouse | IL-25 | type 2 innate lymphoid cells | rhinovirus | Asthma | ALLERGIC INFLAMMATION | IMMUNITY | EARLY-LIFE | DENDRITIC CELLS | RISK | IMMUNOLOGY | VIRAL-INFECTIONS | ALLERGY | RESPIRATORY-SYNCYTIAL-VIRUS | MICE | TH2 | Interleukin-12 Subunit p40 - genetics | Cell Proliferation | Age Factors | Humans | Tumor Necrosis Factor-alpha - genetics | Interleukin-13 - immunology | Respiratory Hypersensitivity - pathology | Interleukins - genetics | Interleukin-13 - genetics | Lymphocytes - immunology | Interleukins - immunology | Tumor Necrosis Factor-alpha - immunology | Interferon-gamma - genetics | Interleukin-12 Subunit p40 - immunology | Rhinovirus - immunology | Child | Picornaviridae Infections - pathology | Animals, Newborn | Lung - pathology | Picornaviridae Infections - immunology | Signal Transduction | Gene Expression Regulation | Respiratory Hypersensitivity - complications | Antibodies, Neutralizing - pharmacology | Respiratory Hypersensitivity - immunology | Interleukins - antagonists & inhibitors | Lymphocytes - pathology | Animals | Interferon-gamma - immunology | Mice | Mucus - immunology | Picornaviridae Infections - complications | Lung - immunology | Infants (Newborn) | Antigens | Flow cytometry | Lymphocytes | Cloning | Infections | Colds | Gene expression | Immune system
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e102606
The human hCLCA1 and its murine ortholog mCLCA3 (calcium-activated chloride channel regulators) are exclusively expressed in mucus cells and linked to... 
ACTIVATED CHLORIDE CHANNEL | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | AIRWAY EPITHELIUM | MUCUS OVERPRODUCTION | ACUTE LUNG INJURY | ASTHMA | CYSTIC-FIBROSIS | MODEL | EXPRESSION | Lung - microbiology | Mucoproteins - immunology | Interleukin-17 - immunology | Bronchoalveolar Lavage Fluid - immunology | Capillary Permeability - immunology | Chloride Channels - genetics | Pneumonia, Staphylococcal - microbiology | Cell Movement - immunology | Leukocytes - immunology | RNA, Messenger - biosynthesis | Female | Bronchoalveolar Lavage Fluid - cytology | Staphylococcal Infections - microbiology | Cytokines - immunology | Disease Models, Animal | Mucoproteins - genetics | Neutrophil Infiltration - immunology | Pneumonia, Staphylococcal - immunology | Lung - pathology | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Cytokines - secretion | Neutrophils - immunology | Chemokine CXCL1 - biosynthesis | Inflammation | Interleukin-17 - biosynthesis | Random Allocation | Chloride Channels - immunology | Mice, Knockout | Mucins - biosynthesis | Chemokine CXCL1 - immunology | Immunity, Innate - immunology | Animals | Staphylococcus aureus - immunology | Mice | Staphylococcus aureus - growth & development | Lung - immunology | Pneumonia | Bacterial infections | RNA | Cytokines | Bacterial pneumonia | Mucins | Staphylococcus aureus infections | Permeability | Comparative analysis | Staphylococcus aureus | Asthma | Regulators | Immune clearance | Mucus | Immunity | Recruitment | Proteins | Histopathology | Respiratory tract diseases | Chronic obstructive pulmonary disease | Nosocomial infections | Pathogens | Pulmonary arteries | Bronchus | Leukocytes (neutrophilic) | Gene expression | Chloride channels (calcium-gated) | Interleukin 17 | Pathology | Metaplasia | Infectious diseases | Fibrosis | Immigration | Infiltration | Cell migration | Calcium | Inflammatory response | Homology | Innate immunity | Infections | Kinases | Macrophages | Rodents | Bacteria | Alveoli | Immune response | Lung diseases | Staphylococcus infections | Cystic fibrosis | Calcium chloride | White blood cells | Signaling | Lungs | Cell number | Laboratory animals | Viral infections
Journal Article
Journal Article