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Chinese Journal of Cancer, ISSN 1000-467X, 2012, Volume 31, Issue 2, pp. 58 - 72
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 2014, Volume 42, Issue 4, pp. 665 - 674
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e63404 - e63404
Although multidrug-resistance-associated protein-1 (MRP1) is a major contributor to multi-drug resistance (MDR), the regulatory mechanism of Mrp1 still remains... 
OXIDATIVE STRESS | GAMMA-GLUTAMYLCYSTEINE SYNTHETASE | TRANSCRIPTION FACTOR NRF2 | MRP/GS-X PUMP | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR P-GLYCOPROTEIN | ANTICANCER DRUGS | DRUG-RESISTANCE | ADAPTIVE RESPONSE | RESPONSIVE ELEMENT | INDUCIBLE EXPRESSION | Immunohistochemistry | Antioxidants - metabolism | Drug Resistance, Multiple - drug effects | Humans | Lung Neoplasms - metabolism | Molecular Sequence Data | 5' Flanking Region - genetics | Gene Knockdown Techniques | Small Cell Lung Carcinoma - metabolism | Base Sequence | Multidrug Resistance-Associated Proteins - genetics | Antineoplastic Agents - pharmacology | Response Elements - genetics | Gene Expression Regulation, Neoplastic - drug effects | Lung Neoplasms - genetics | Drug Resistance, Multiple - genetics | Signal Transduction - genetics | Small Cell Lung Carcinoma - genetics | Mutation - genetics | Drug Resistance, Neoplasm - genetics | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | NAD(P)H Dehydrogenase (Quinone) - metabolism | Software | Multidrug Resistance-Associated Proteins - metabolism | Drug Resistance, Neoplasm - drug effects | Chemotherapy | Comparative analysis | Drug resistance | Lung cancer | Cancer | Drugs | Oxidative stress | Enzymes | Genes | Multidrug resistance | Regulatory sequences | Drug development | Gene expression | Tissues | Cancer therapies | Proteins | Antioxidants | Pathology | Toxicology | Reporter gene | Correlation analysis | Rodents | Regulatory mechanisms (biology) | Localization | MRP1 protein | Index Medicus
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2012, Volume 265, Issue 3, pp. 316 - 324
Emodin is a poorly bioavailable but promising plant-derived anticancer drug candidate. The low oral bioavailability of emodin is due to its extensive... 
Emodin | UDP-glucuronosyltransferases | Caco-2 cells | Multidrug resistance-associated proteins | Intestinal disposition | BCRP | UGT | MRP | NTP | DMEM | UPLC | UDPGA | TEER | LTC4 | AIC | HBSS | CELL-CULTURE MODEL | TRANSPORTER | FLAVONOIDS | MECHANISMS | IN-VITRO | METABOLISM | ANTHRAQUINONES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ABSORPTION | EXPRESSION | Caco-2 Cells | Propionates - pharmacology | Humans | Biological Availability | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Intestines - metabolism | Intestinal Absorption | Quinolines - pharmacology | Emodin - pharmacokinetics | Biological Transport | Glucuronosyltransferase - metabolism | Leukotriene C4 - pharmacology | Multidrug Resistance-Associated Proteins - metabolism | Intestines - enzymology | Proteins | Physiological aspects | Chemical inhibitors | Permeability | Analysis | Index Medicus | Cell culture | Excretion | MRP protein | UDP-glucuronosyltransferase | Liver | Dipyridamole | Breast cancer | Plants | Antitumor agents | Intestine | Disposition | Metabolic pathways | Protein transport | BIOLOGICAL PATHWAYS | MAMMARY GLANDS | NEOPLASMS | CELL CULTURES | BIOLOGICAL AVAILABILITY | INTESTINES | URIDINE | ANTINEOPLASTIC DRUGS | EXCRETION | 60 APPLIED LIFE SCIENCES | CONCENTRATION RATIO | DIPYRIDAMOLE | LIQUID COLUMN CHROMATOGRAPHY | LIVER | PROTEINS
Journal Article
Journal Article
AMERICAN JOURNAL OF TRANSPLANTATION, ISSN 1600-6135, 05/2005, Volume 5, Issue 5, pp. 987 - 994
In mycophenolate mofetil (MMF)- treated organ transplant recipients, lower mycophenolic acid (MPA) plasma concentrations have been found in cyclosporine (CsA)... 
cyclosporine | CONJUGATE EXPORT PUMP | RAT-LIVER | SURGERY | multidrug resistance-associated protein 2 | ATP-DEPENDENT TRANSPORT | TR-RATS | GLUCURONIDE | tacrolimus | mycophenolic acid | MRP3 | KIDNEY-TRANSPLANT RECIPIENTS | PHARMACOKINETICS | drug interaction | transplantation | EXPRESSION
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 01/2017, Volume 1859, Issue 1, pp. 69 - 79
Multidrug resistance (MDR) is the main cause of diminished success in cancer chemotherapy. ABC transport proteins are considered to be one important factor of... 
MRP1 | ABCC1 | Transport activation | Flux ratio | Activator | ABC transporter | GLUTATHIONE TRANSPORT | BIOCHEMISTRY & MOLECULAR BIOLOGY | GSH EFFLUX | P-GLYCOPROTEIN | SUBSTRATE-SPECIFICITY | BIOPHYSICS | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | CYSTEINE SUBSTITUTIONS | TRANSPORT ACTIVITY | BIOLOGICAL EVALUATION | SELECTIVE INHIBITORS | HUMAN TUMOR-CELLS | Pyrimidines - chemical synthesis | Drug Resistance, Multiple - drug effects | Fluoresceins - metabolism | Humans | Daunorubicin - pharmacology | Fluorescent Dyes - metabolism | Structure-Activity Relationship | Neoplasm Proteins - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | ATP Binding Cassette Transporter, Sub-Family B - agonists | Madin Darby Canine Kidney Cells | Multidrug Resistance-Associated Proteins - genetics | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Purines - chemical synthesis | Gene Expression | Drug Resistance, Multiple - genetics | Purines - pharmacology | Pyrimidines - pharmacology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - agonists | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - genetics | Drug Resistance, Neoplasm - genetics | Pyrroles - pharmacology | Animals | Pyrroles - chemical synthesis | Neoplasm Proteins - agonists | Dogs | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Cell Line, Tumor | Multidrug Resistance-Associated Proteins - agonists | Kinetics | ATP Binding Cassette Transporter, Sub-Family B - genetics | Multidrug Resistance-Associated Proteins - metabolism | Drug Resistance, Neoplasm - drug effects | Alkaloids | Drug resistance in microorganisms | Chemotherapy | Anthracyclines | Carrier proteins | Lung cancer | Cancer | Index Medicus
Journal Article
Journal Article
Journal Article