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Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e63404 - e63404
Although multidrug-resistance-associated protein-1 (MRP1) is a major contributor to multi-drug resistance (MDR), the regulatory mechanism of Mrp1 still remains... 
OXIDATIVE STRESS | GAMMA-GLUTAMYLCYSTEINE SYNTHETASE | TRANSCRIPTION FACTOR NRF2 | MRP/GS-X PUMP | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR P-GLYCOPROTEIN | ANTICANCER DRUGS | DRUG-RESISTANCE | ADAPTIVE RESPONSE | RESPONSIVE ELEMENT | INDUCIBLE EXPRESSION | Immunohistochemistry | Antioxidants - metabolism | Drug Resistance, Multiple - drug effects | Humans | Lung Neoplasms - metabolism | Molecular Sequence Data | 5' Flanking Region - genetics | Gene Knockdown Techniques | Small Cell Lung Carcinoma - metabolism | Base Sequence | Multidrug Resistance-Associated Proteins - genetics | Antineoplastic Agents - pharmacology | Response Elements - genetics | Gene Expression Regulation, Neoplastic - drug effects | Lung Neoplasms - genetics | Drug Resistance, Multiple - genetics | Signal Transduction - genetics | Small Cell Lung Carcinoma - genetics | Mutation - genetics | Drug Resistance, Neoplasm - genetics | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | NAD(P)H Dehydrogenase (Quinone) - metabolism | Software | Multidrug Resistance-Associated Proteins - metabolism | Drug Resistance, Neoplasm - drug effects | Chemotherapy | Comparative analysis | Drug resistance | Lung cancer | Cancer | Drugs | Oxidative stress | Enzymes | Genes | Multidrug resistance | Regulatory sequences | Drug development | Gene expression | Tissues | Cancer therapies | Proteins | Antioxidants | Pathology | Toxicology | Reporter gene | Correlation analysis | Rodents | Regulatory mechanisms (biology) | Localization | MRP1 protein | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2002, Volume 277, Issue 4, pp. 2908 - 2915
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 500, Issue 7460, pp. 102 - 106
The multidrug efflux transporter AcrB and its homologues are important in the multidrug resistance of Gram-negative pathogens(1,2). However, despite efforts to... 
GRAM-NEGATIVE BACTERIA | EFFLUX PUMP INHIBITORS | PSEUDOMONAS-AERUGINOSA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | RESISTANCE | TRANSPORTER ACRB | BINDING POCKET | SITE-DIRECTED MUTAGENESIS | STRATEGIES | Pyridines - chemistry | Protein Multimerization | Crystallography, X-Ray | Pyrimidinones - metabolism | Pyrimidines - chemistry | Pyrimidines - metabolism | Pyrimidinones - chemistry | Pseudomonas aeruginosa - metabolism | Anti-Bacterial Agents - chemistry | Membrane Transport Proteins - metabolism | Pyrimidinones - pharmacology | Escherichia coli Proteins - antagonists & inhibitors | Binding Sites | Bacterial Outer Membrane Proteins - antagonists & inhibitors | Multidrug Resistance-Associated Proteins - chemistry | Bacterial Outer Membrane Proteins - chemistry | Models, Molecular | Anti-Bacterial Agents - metabolism | Escherichia coli Proteins - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Pyrimidines - pharmacology | Escherichia coli - chemistry | Rotation | Membrane Transport Proteins - chemistry | Pseudomonas aeruginosa - chemistry | Pyridines - metabolism | Bacterial Outer Membrane Proteins - metabolism | Hydrophobic and Hydrophilic Interactions | Anti-Bacterial Agents - pharmacology | Pyridines - pharmacology | Escherichia coli Proteins - chemistry | Multidrug Resistance-Associated Proteins - metabolism | Drug resistance in microorganisms | Pseudomonas aeruginosa | Research | Structure | Identification and classification | Crystals | Physiological aspects | Microbiological research | Biological transport | Proteins | Antibiotics | Bacteriology | Crystal structure | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 49, pp. 21187 - 21192
Journal Article
Nature Communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10731 - 10731
Journal Article