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Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2006, Volume 281, Issue 43, pp. 32207 - 32216
AMP-activated protein kinase (AMPK) is a heterotrimeric protein kinase that is crucial for cellular energy homeostasis of eukaryotic cells and organisms. Here... 
CELLS | ENERGY HOMEOSTASIS | PHOSPHORYLATION | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | UPSTREAM KINASE | CELLULAR-ENERGY | CREATINE-KINASE | SUBUNIT | BETA | Protein Kinases - metabolism | Protein-Serine-Threonine Kinases - analysis | Phosphorylation | Multienzyme Complexes - metabolism | AMP-Activated Protein Kinases | Aminoimidazole Carboxamide - pharmacology | Recombinant Proteins - isolation & purification | Ribonucleotides - pharmacology | Protein Isoforms - metabolism | Allosteric Regulation - physiology | Adenosine Triphosphate - metabolism | Protein-Serine-Threonine Kinases - metabolism | Recombinant Proteins - metabolism | Adenosine Monophosphate - metabolism | NAD - pharmacology | Protein-Serine-Threonine Kinases - genetics | Glutathione Transferase - metabolism | Multienzyme Complexes - genetics | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Mice | Enzyme Activation | Multienzyme Complexes - analysis | Mutation | In Vitro Techniques | Protein Isoforms - genetics | Multienzyme Complexes | Allosteric Regulation | Protein-Serine-Threonine Kinases | Biochemistry, Molecular Biology | Adenosine Triphosphate | Recombinant Proteins | Adenosine Monophosphate | NAD | Life Sciences | Aminoimidazole Carboxamide | Ribonucleotides | Protein Kinases | Protein Isoforms | Glutathione Transferase
Journal Article
FASEB Journal, ISSN 0892-6638, 07/2005, Volume 19, Issue 9, pp. 1146 - 1148
We tested the hypothesis that 5'AMP-activated protein kinase (AMPK) plays an important role in regulating the acute, exercise-induced activation of metabolic... 
adenosine nucleotides | gene transcription | TRANSCRIPTIONAL ACTIVATION | PGC-1 alpha | inosine monophosphate | MITOCHONDRIAL BIOGENESIS | 5'-AMP-ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | mRNA | GLUCOSE-TRANSPORT | ACETYL-COA CARBOXYLASE | ENERGY DEPRIVATION | CELL BIOLOGY | SUBSTRATE-SPECIFICITY | BIOLOGY | PDK4 | FIBER-TYPE | AICAR | PHYSICAL-ACTIVITY | GLYCOGEN-SYNTHASE KINASE | Protein-Serine-Threonine Kinases - analysis | Protein Kinases - genetics | Ion Channels | Transcriptional Activation | Multienzyme Complexes - metabolism | RNA, Messenger - analysis | Male | Muscle, Skeletal - metabolism | Mitochondrial Proteins | AMP-Activated Protein Kinases | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Inosine Monophosphate - analysis | Trans-Activators - genetics | Female | Transcription, Genetic | Hexokinase - genetics | Glycogen - analysis | Physical Conditioning, Animal | Protein-Serine-Threonine Kinases - metabolism | Adenosine Monophosphate - analysis | Protein-Serine-Threonine Kinases - physiology | Adenosine Triphosphate - analysis | Acetyl-CoA Carboxylase - analysis | Gene Expression Regulation | Mice, Knockout | Carrier Proteins - genetics | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Multienzyme Complexes - physiology | Mice | Transcription Factors | Multienzyme Complexes - analysis | Uncoupling Protein 3
Journal Article
Diabetes, ISSN 0012-1797, 08/2006, Volume 55, Issue 8, pp. 2277 - 2285
Increased Malonyl-CoA Levels in Muscle From Obese and Type 2 Diabetic Subjects Lead to Decreased Fatty Acid Oxidation and Increased Lipogenesis;... 
ACC, acetyl-CoA carboxylase | FAT/CD36, fatty acid translocator membrane glycoprotein 36 | AMPK, AMP-activated protein kinase | FATP, fatty acid transport protein | MCD, malonyl-CoA decarboxylase | ALBP, adipocyte lipid-binding protein | METABOLIC SYNDROME | ACTIVATED PROTEIN-KINASE | PLASMA ADIPONECTIN | ENDOCRINOLOGY & METABOLISM | AMP-KINASE | GLOBULAR ADIPONECTIN | COENZYME-A | EXPRESSION | HUMAN SKELETAL-MUSCLE | INDUCED INSULIN-RESISTANCE | ADIPOSE-TISSUE | Protein-Serine-Threonine Kinases - analysis | Humans | Middle Aged | Mitochondria, Muscle - metabolism | Multienzyme Complexes - metabolism | Male | Diabetes Mellitus, Type 2 - metabolism | Lipids - biosynthesis | AMP-Activated Protein Kinases | Thiazolidinediones - therapeutic use | Triglycerides - analysis | Acyl Coenzyme A - analysis | Muscle, Skeletal - chemistry | Adult | Female | Fatty Acids - metabolism | Protein-Serine-Threonine Kinases - metabolism | Hypoglycemic Agents - therapeutic use | Oxidation-Reduction | Fatty Acid Transport Proteins - analysis | Acetyl-CoA Carboxylase - analysis | Insulin Resistance | Carboxy-Lyases - analysis | Obesity - metabolism | Glucose Clamp Technique | Multienzyme Complexes - analysis | Malonyl Coenzyme A - analysis | Type 2 diabetes | Care and treatment | Genetic aspects | Research | Diabetes | Gene expression | Health aspects
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 04/2009, Volume 29, Issue 8, pp. 2155 - 2167
Journal Article
Brazilian Journal of Medical and Biological Research, ISSN 0100-879X, 2018, Volume 51, Issue 11, p. e7660
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 2019, Volume 76, Issue 12, pp. 2329 - 2348
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2005, Volume 11, Issue 7, pp. 2552 - 2560
Purpose: Human leukocyte antigen (HLA) class I antigen defects, which are frequently present in head and neck squamous cell carcinoma (HNSCC) cells may provide... 
MHC class I | prognostic marker | antigen processing | head and neck cancer | LYMPH-NODE METASTASES | HLA CLASS-I | ONCOLOGY | LARYNGEAL CARCINOMAS | DOWN-REGULATION | HIGH-FREQUENCY | TUMOR-CELLS | MAJOR HISTOCOMPATIBILITY COMPLEX | EXPRESSION | CANCER | EFFECTOR-CELLS | Immunohistochemistry | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | HLA Antigens - genetics | Histocompatibility Antigens Class I - analysis | Proteasome Endopeptidase Complex | Head and Neck Neoplasms - metabolism | ATP-Binding Cassette, Sub-Family B, Member 3 | Cysteine Endopeptidases - analysis | ATP-Binding Cassette Transporters - genetics | Adult | Female | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Cell Line | Histocompatibility Antigens Class I - genetics | Multienzyme Complexes - genetics | Down-Regulation - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | ATP-Binding Cassette Transporters - analysis | Head and Neck Neoplasms - pathology | HLA Antigens - analysis | Cysteine Endopeptidases - genetics | Survival Analysis | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Aged | Multienzyme Complexes - analysis | ATP-Binding Cassette Sub-Family B Member 2 | Interferon-gamma - pharmacology
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0169259
We describe a gentle and rapid method to purify the intact multiprotein DNA replication complex using free flow electrophoresis (FFE). In particular, we... 
IN-VITRO | MULTIDISCIPLINARY SCIENCES | TCA CYCLE ENZYMES | RESOLUTION | CELL-CYCLE | SEPARATION | IDENTIFICATION | SYNTHESOME | MEMBRANE-PROTEIN COMPLEXES | MASS-SPECTROMETRY | LIVING CELLS | DNA-Directed DNA Polymerase - isolation & purification | DNA Polymerase III - isolation & purification | DNA-Directed DNA Polymerase - analysis | Humans | DNA Polymerase II - isolation & purification | Cell Extracts - chemistry | DNA Replication | Proliferating Cell Nuclear Antigen - analysis | Replication Protein A - isolation & purification | Simian virus 40 - genetics | Replication Origin - genetics | Replication Protein C - isolation & purification | Cell Line, Tumor | Antigens, Viral, Tumor - genetics | Electrophoresis - methods | HeLa Cells | Multienzyme Complexes - analysis | DNA Polymerase I - isolation & purification | Multienzyme Complexes - isolation & purification | DNA Topoisomerases, Type I - isolation & purification | Electrophoresis | DNA replication | Usage | Research | Mass spectrometry | Drugs | DNA polymerase | Antigen T (large) | Viruses | Biochemistry | Biosynthesis | DNA repair | Gene sequencing | Proteins | Spectrometry | Cell cycle | Proliferating cell nuclear antigen | Replication factor C | Free flow | Deoxyribonucleic acid--DNA | Antigens | Enzymes | Elution | Gels | Cyclin-dependent kinases | DNA topoisomerase | Glycerol | Replication protein A | Protein A | Chromatography | DNA biosynthesis | Polymerase | Replication origins | Cellular biology | Electrophoretic mobility | Replication | DNA-directed DNA polymerase | Methods | DNA sequencing | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Journal Article