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Oncogene, ISSN 0950-9232, 03/2019, Volume 38, Issue 13, pp. 2241 - 2262
The poor outcomes in infant acute lymphoblastic leukemia (ALL) necessitate new treatments. Here we discover that EIF4E protein is elevated in most cases of... 
PROGNOSTIC-FACTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMPROVED SURVIVAL | INITIATION-FACTOR EIF4E | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | ANTIVIRAL DRUG | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | FACTOR 4E | RNA REGULON | CELL-CYCLE | Humans | Ribavirin - therapeutic use | Eukaryotic Initiation Factor-4E - physiology | Child, Preschool | Gene Expression Regulation, Leukemic - drug effects | Infant | Gene Expression Profiling | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Drug Resistance, Neoplasm - genetics | Signal Transduction - drug effects | Microarray Analysis | Cell Line, Tumor | Protein Biosynthesis - drug effects | Multigene Family - drug effects | Pyrroles - therapeutic use | Eukaryotic Initiation Factor-4E - genetics | Molecular Targeted Therapy - methods | Drug Resistance, Neoplasm - drug effects | Cell proliferation | Phosphorylation | AKT1 protein | Acute lymphatic leukemia | Cell survival | Therapeutic applications | Leukemia | L-asparaginase | Myc protein | Lymphatic leukemia | Kinases | Ribavirin | Mcl-1 protein | Proteins | Chemotherapy | Stromal cells | Cell cycle | Xenografts | Bone marrow | Initiation factor eIF-4E | Asparaginase | Cytoplasm | Index Medicus | Infant, KMT2A | Obatoclax | Acute lymphoblastic leukemia | EIF4E
Journal Article
Blood, ISSN 0006-4971, 09/2011, Volume 118, Issue 13, pp. 3579 - 3590
Journal Article
Human Genetics, ISSN 0340-6717, 3/2007, Volume 121, Issue 1, pp. 23 - 34
Journal Article
Molecular Genetics and Genomics, ISSN 1617-4615, 3/2011, Volume 285, Issue 3, pp. 245 - 260
Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 03/2010, Volume 9, Issue 3, pp. 545 - 557
ABT-263 inhibits the antiapoptotic proteins Bcl-2, Bcl-xL, and Bcl-w and has single-agent efficacy in numerous small cell lung carcinoma (SCLC) and... 
APOPTOSIS | CANCER CELLS | SOLID TUMORS | ONCOLOGY | PATIENT SELECTION | GENE-EXPRESSION | CHRONIC LYMPHOCYTIC-LEUKEMIA | DRUG-RESISTANCE | BH3 MIMETIC ABT-737 | PROTEINS | UP-REGULATION | Leukemia - pathology | Prognosis | Oligonucleotide Array Sequence Analysis | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Leukemia - metabolism | Gene Regulatory Networks - drug effects | Lymphoma - metabolism | Small Cell Lung Carcinoma - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Lymphoma - pathology | Antineoplastic Agents - pharmacology | Multigene Family - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Leukemia - genetics | Lung Neoplasms - genetics | Biomarkers, Pharmacological - analysis | Aniline Compounds - pharmacology | Lymphoma - diagnosis | Lymphoma - genetics | Small Cell Lung Carcinoma - genetics | Sulfonamides - pharmacology | Drug Resistance, Neoplasm - genetics | Small Cell Lung Carcinoma - pathology | Sulfonamides - therapeutic use | Cell Line, Tumor | Leukemia - diagnosis | Small Cell Lung Carcinoma - diagnosis | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aniline Compounds - therapeutic use | Lung Neoplasms - diagnosis | Biomarkers, Pharmacological - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Index Medicus
Journal Article
Journal Article
Molecular Genetics and Genomics, ISSN 1617-4615, 5/2012, Volume 287, Issue 5, pp. 389 - 410
The NAC (NAM, ATAF1/2 and CUC2) genes are plant-specific transcriptional factors known to play diverse roles in various plant developmental processes. We... 
Life Sciences | Biochemistry, general | Hormone | Expression profile | Microbial Genetics and Genomics | NILs | Microarray | Stress | Plant Genetics & Genomics | Animal Genetics and Genomics | Cell Biology | TRANSCRIPTION FACTOR FAMILY | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGULATORY NETWORK | SALT TOLERANCE | WATER-DEFICIT | RESPONSIVE GENES | ORYZA-SATIVA | GENETICS & HEREDITY | FUNCTIONAL-ANALYSIS | GRAIN-YIELD | ARABIDOPSIS | REVEALS | Flowering Tops - drug effects | Flowering Tops - genetics | Stress, Physiological - genetics | Oryza - physiology | Plant Roots - genetics | Gene Expression Profiling | Oryza - drug effects | RNA, Plant - genetics | Transcription Factors - genetics | Genetic Complementation Test | Plant Roots - drug effects | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Oryza - growth & development | Oryza - genetics | Plant Leaves - genetics | Droughts | Genes, Regulator | Models, Genetic | Multigene Family - drug effects | Plant Leaves - drug effects | Genes, Plant - drug effects | Plant Growth Regulators - pharmacology | Crosses, Genetic | Biotechnology | Soil moisture | Genes | Plant genetics | Genetic transcription | Hormones | Gene expression | Anopheles | Phytochemistry | Genetic research | Universities and colleges | Rice | Index Medicus | Growth conditions | Transcription factors | Transcription | Gene families | Roots | Acetylcysteine | Leaves | Life cycle | Soil | Genotypes | Original Paper
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0135284 - e0135284
Journal Article
Journal Article