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1. Full Text Initial genome sequencing and analysis of multiple myeloma
by Chapman, Michael A and Lawrence, Michael S and Keats, Jonathan J and Cibulskis, Kristian and Sougnez, Carrie and Schinzel, Anna C and Harview, Christina L and Brunet, Jean-Philippe and Ahmann, Gregory J and Adli, Mazhar and Anderson, Kenneth C and Ardlie, Kristin G and Auclair, Daniel and Baker, Angela and Bergsagel, P. Leif and Bernstein, Bradley E and Drier, Yotam and Fonseca, Rafael and Gabriel, Stacey B and Hofmeister, Craig C and Jagannath, Sundar and Jakubowiak, Andrzej J and Krishnan, Amrita and Levy, Joan and Liefeld, Ted and Lonial, Sagar and Mahan, Scott and Mfuko, Bunmi and Monti, Stefano and Perkins, Louise M and Onofrio, Robb and Pugh, Trevor J and Rajkumar, S. Vincent and Ramos, Alex H and Siegel, David S and Sivachenko, Andrey and Stewart, A. Keith and Trudel, Suzanne and Vij, Ravi and Voet, Douglas and Winckler, Wendy and Zimmerman, Todd and Carpten, John and Trent, Jeff and Hahn, William C and Garraway, Levi A and Meyerson, Matthew and Lander, Eric S and Getz, Gad and Golub, Todd R
Nature (London), ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 467 - 472
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Hematologic and hematopoietic diseases | Immunopathology | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Immunoglobulinopathies | Medical sciences | Immunodeficiencies. Immunoglobulinopathies | Ribonucleases - genetics | Ribonucleases - chemistry | Genomics | Humans | Molecular Sequence Data | NF-kappa B - metabolism | DNA Repair - genetics | Multiple Myeloma - drug therapy | DNA Mutational Analysis | Protein Biosynthesis - genetics | Multiple Myeloma - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Amino Acid Sequence | Oncogenes - genetics | Models, Molecular | Exons - genetics | Signal Transduction - genetics | Multiple Myeloma - metabolism | Mutation - genetics | Open Reading Frames - genetics | Genome, Human - genetics | Homeodomain Proteins - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | RNA Processing, Post-Transcriptional - genetics | Proto-Oncogene Proteins B-raf - genetics | CpG Islands - genetics | Blood Coagulation - genetics | Protein Conformation | Histones - metabolism | Transcription, Genetic - genetics | Exosome Multienzyme Ribonuclease Complex | Methylation | Homeostasis - genetics | Multiple Myeloma - genetics | Usage | Multiple myeloma | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Methods | Cancer | Proteins | Pathogenesis | Homeostasis | Genetics | Genomes | Mutation | Kinases | Mass spectrometry | Index Medicus
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2. Full Text Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease
by Fu, Jing and Li, Shirong and Feng, Rentian and Ma, Huihui and Sabeh, Farideh and Roodman, G. David and Wang, Ji and Robinson, Samuel and Guo, X. Edward and Lund, Thomas and Normolle, Daniel and Mapara, Markus Y and Weiss, Stephen J and Lentzsch, Suzanne
The Journal of clinical investigation, ISSN 0021-9738, 05/2016, Volume 126, Issue 5, pp. 1759 - 1772
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Neoplasm Transplantation | Osteoclasts - pathology | Osteolysis - genetics | Humans | Matrix Metalloproteinase 13 - genetics | Male | Neoplasm Proteins - metabolism | Matrix Metalloproteinase 13 - metabolism | Mice, Knockout | Cell Fusion | Multiple Myeloma - pathology | Multiple Myeloma - therapy | Osteolysis - therapy | Animals | Heterografts | Osteolysis - enzymology | Female | Mice | Osteoclasts - enzymology | Multiple Myeloma - enzymology | Neoplasm Proteins - genetics | Multiple Myeloma - genetics | Osteolysis - pathology | Physiological aspects | Complications and side effects | Enzymes | Care and treatment | Research | Multiple myeloma | Studies | Bone diseases | Phosphatase | Index Medicus | Abridged Index Medicus
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3. Full Text The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma
by Glavey, Siobhan V and Manier, Salomon and Natoni, Alessandro and Sacco, Antonio and Moschetta, Michele and Reagan, Michaela R and Murillo, Laura S and Sahin, Ilyas and Wu, Ping and Mishima, Yuji and Zhang, Y and Zhang, Wenjing and Zhang, Yong and Morgan, Gareth and Joshi, Lokesh and Roccaro, Aldo M and Ghobrial, Irene M and O'Dwyer, Michael E
Blood, ISSN 0006-4971, 2014, Volume 124, Issue 11, pp. 1765 - 1776
Life Sciences & Biomedicine | Hematology | Science & Technology | Human Umbilical Vein Endothelial Cells | Bone Marrow Cells - enzymology | Stromal Cells - pathology | Humans | N-Acetylneuraminic Acid - biosynthesis | Cell Survival - genetics | Male | Neoplasm Proteins - metabolism | Gene Knockdown Techniques | Stromal Cells - enzymology | Transendothelial and Transepithelial Migration | N-Acetylneuraminic Acid - genetics | Female | Multiple Myeloma - enzymology | Neoplasm Proteins - genetics | Cell Adhesion - genetics | Bone Marrow Cells - pathology | Sialyltransferases - genetics | Mice, SCID | Sialyltransferases - metabolism | Multiple Myeloma - pathology | Animals | Cell Line, Tumor | Mice | Multiple Myeloma - genetics | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia | 102 | 39 | 29
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4. Full Text Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
by Obeng, Esther A and Carlson, Louise M and Gutman, Delia M and Harrington Jr, William J and Lee, Kelvin P and Boise, Lawrence H
Blood, ISSN 0006-4971, 06/2006, Volume 107, Issue 12, pp. 4907 - 4916
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Chemotherapy | Pharmacology. Drug treatments | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Antineoplastic agents | Endoplasmic Reticulum - enzymology | Cell Survival - drug effects | Bortezomib | Apoptosis - drug effects | Neoplasm Proteins - biosynthesis | Humans | Pyrazines - therapeutic use | Boronic Acids - therapeutic use | Protein Folding | Plasma Cells - pathology | Plasma Cells - enzymology | Protease Inhibitors - pharmacology | Multiple Myeloma - drug therapy | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Line, Tumor | Proteasome Endopeptidase Complex - metabolism | Multiple Myeloma - enzymology | Protease Inhibitors - therapeutic use | Proteasome Inhibitors | Pyrazines - pharmacology | Boronic Acids - pharmacology | Index Medicus | Abridged Index Medicus | Neoplasia
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5. Full Text The proteasome and proteasome inhibitors in multiple myeloma
by Gandolfi, Sara and Laubach, Jacob P and Hideshima, Teru and Chauhan, Dharminder and Anderson, Kenneth C and Richardson, Paul G
Cancer and metastasis reviews, ISSN 0167-7659, 12/2017, Volume 36, Issue 4, pp. 561 - 584
Biomedicine, general | Biomedicine | Proteasome inhibitor | Multiple myeloma | Tumor progression | Cancer Research | Oncology | 20S proteasome | Ubiquitin-proteasome system | Life Sciences & Biomedicine | Science & Technology | Multiple Myeloma - drug therapy | Proteasome Inhibitors - pharmacology | Humans | Proteasome Inhibitors - administration & dosage | Drug Resistance, Neoplasm | Proteasome Endopeptidase Complex - metabolism | Multiple Myeloma - enzymology | Randomized Controlled Trials as Topic | Ubiquitin | Chemotherapy | Biological products | Monoclonal antibodies | Development and progression | Drug approval | Cancer | Drugs | NF-κB protein | Histone deacetylase | Bortezomib | Immunomodulation | Pathogenesis | Downstream effects | Growth factor receptors | FDA approval | Proteasome inhibitors | Proteins | Angiogenesis | Signaling | Receptors | Biological effects | Inhibitors | Protease inhibitors | Protein folding | Reagents | Inhibition | Endoplasmic reticulum | Index Medicus
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6. Full Text Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma
by Lamy, Laurence and Ngo, Vu N and Emre, N.C. Tolga and Shaffer, Arthur L and Yang, Yandan and Tian, Erming and Nair, Vinod and Kruhlak, Michael J and Zingone, Adriana and Landgren, Ola and Staudt, Louis M
Cancer cell, ISSN 1535-6108, 04/2013, Volume 23, Issue 4, pp. 435 - 449
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Survival - drug effects | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Humans | Caspase 10 - metabolism | Autophagy - physiology | Autophagy - drug effects | Gene Knockdown Techniques | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | RNA Interference | Caspase 10 - genetics | Cell Line, Tumor | Apoptosis - physiology | Multiple Myeloma - enzymology | Cell Survival - physiology | Multiple Myeloma - genetics | Biochemistry | RNA | Proteases | Cell death | Multiple myeloma | Index Medicus
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7. Full Text Low expression of hexokinase-2 is associated with false-negative FDG–positron emission tomography in multiple myeloma
by Rasche, Leo and Angtuaco, Edgardo and McDonald, James E and Buros, Amy and Stein, Caleb and Pawlyn, Charlotte and Thanendrarajan, Sharmilan and Schinke, Carolina and Samant, Rohan and Yaccoby, Shmuel and Walker, Brian A and Epstein, Joshua and Zangari, Maurizio and Van Rhee, Frits and Meissner, Tobias and Goldschmidt, Hartmut and Hemminki, Kari and Houlston, Richard and Barlogie, Bart and Davies, Faith E and Morgan, Gareth J and Weinhold, Niels
Blood, ISSN 0006-4971, 07/2017, Volume 130, Issue 1, pp. 30 - 34
Life Sciences & Biomedicine | Hematology | Science & Technology | Fluorodeoxyglucose F18 - administration & dosage | Multiple Myeloma - diagnostic imaging | Gene Expression Regulation, Enzymologic - drug effects | Hexokinase - biosynthesis | Neoplasm Proteins - biosynthesis | Humans | Female | Male | Positron-Emission Tomography | Gene Expression Regulation, Neoplastic - drug effects | False Positive Reactions | Multiple Myeloma - enzymology | Index Medicus | Abridged Index Medicus | Clinical Trials and Observations | Brief Report | 102 | Clinical Medicine | Hematologi | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Cancer and Oncology | Cancer och onkologi
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