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1. Full Text Deciding on the Best Multiple Sclerosis Therapy: Tough Choices
by Berger, Joseph R and Markowitz, Clyde
JAMA Neurology, ISSN 2168-6149, 12/2018, Volume 75, Issue 12, pp. 1461 - 1462
As of January 1, 2018, there are 18 US Food and Drug Administration (FDA)–approved therapies for relapsing-remitting multiple sclerosis (MS) with more on the... 
CLINICAL NEUROLOGY | Exhausting | Neurology | Regulatory agencies | Multiple sclerosis | Medical treatment | Fatigue | FDA approval | Medical diagnosis | Risk analysis | Disease control
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2. Full Text Quality Assessment in Multiple Sclerosis Therapy (QUASIMS)
: A comparison of interferon beta therapies for relapsing-remitting multiple sclerosis
by Limmroth, Volker and Malessa, Rolf and Zettl, Uwe Klaus and Koehler, Jürgen and Japp, Gudrun and Haller, Peter and Elias, Wolfgang and Obhof, Winfried and Viehöver, Andrea and Meier, Uwe and Brosig, Arne and Hasford, Joerg and Putzki, Norman and Kalski, Gabriele and Wernsdörfer, Colin and QUASIMS Study Group and for the QUASIMS Study Group
Journal of Neurology, ISSN 0340-5354, 1/2007, Volume 254, Issue 1, pp. 67 - 77
Interferon beta (IFNβ) preparations are the most frequently prescribed therapies for patients with relapsing multiple sclerosis (MS). Several open-label... 
interferon beta | Neurology | Neurosciences | Medicine & Public Health | multiple sclerosis | disease-modifying therapy | Neuroradiology | Disease-modifying therapy | Multiple sclerosis | Interferon beta | MULTICENTER | DOUBLE-BLIND | MAGNETIC-RESONANCE | EXPERIENCE | PLACEBO-CONTROLLED TRIAL | CLINICAL NEUROLOGY | Disability Evaluation | Severity of Illness Index | Drug Administration Schedule | Outcome Assessment (Health Care) | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Humans | Middle Aged | Male | Dose-Response Relationship, Drug | Interferon-beta - therapeutic use | Adolescent | Observation - methods | Adult | Female | Retrospective Studies | Cohort Studies | Immunologic Factors - therapeutic use | Care and treatment | Relapse | Health aspects | Diseases | Index Medicus
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3. Full Text The new era of multiple sclerosis therapy
by Olsson, T
Journal of Internal Medicine, ISSN 0954-6820, 04/2014, Volume 275, Issue 4, pp. 382 - 386
CRITERIA | MEDICINE, GENERAL & INTERNAL | SMOKING | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | INCREASED RISK | AGE | Adjuvants, Immunologic - therapeutic use | Multiple Sclerosis - therapy | Humans | Immunosuppressive Agents - therapeutic use | Multiple Sclerosis - drug therapy | Multiple sclerosis | Index Medicus
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4. Full Text Symptomatic treatment of multiple sclerosis: Multiple Sclerosis Therapy Consensus Group (MSTCG) of the German Multiple Sclerosis Society
by Henze, T and Rieckmann, P and Toyka, K.V and Multiple Sclerosis Therapy Consensus Group of the German Multiple Sclerosis Society
European Neurology, ISSN 0014-3022, 10/2006, Volume 56, Issue 2, pp. 78 - 105
Besides immunomodulation and immunosuppression, the specific treatment of symptoms is an essential component of the overall management of multiple sclerosis... 
Symptomatic treatment | Multiple sclerosis | Consensus guidelines | Expert opinion | Evidence-based medicine | Multiple Sclerosis - complications | Multiple Sclerosis - therapy | Humans | Index Medicus
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5. Full Text Calming Down Mast Cells with Ketotifen: A Potential Strategy for Multiple Sclerosis Therapy?
by Pinke, Karen Henriette and Zorzella-Pezavento, Sofia Fernanda Gonçalves and de Campos Fraga-Silva, Thais Fernanda and Mimura, Luiza Ayumi Nishiyama and de Oliveira, Larissa Ragozo Cardoso and Ishikawa, Larissa Lumi Watanabe and Fernandes, Ana Angélica Henrique and Lara, Vanessa Soares and Sartori, Alexandrina
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, ISSN 1933-7213, 08/2019, pp. 1 - 17
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by extensive inflammation, demyelination, axonal loss... 
Oxidative stress | Multiple sclerosis | Immunization | Animal models | Oligodendrocyte-myelin glycoprotein | Encephalomyelitis | Cytokines | Central nervous system | Lymphocytes T | Permeability | Gene expression | Drug development | Experimental allergic encephalomyelitis | Cell activation | Gliosis | Demyelination | Immunopathogenesis | Mast cells | Autoimmune diseases | Index Medicus
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6. Full Text Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: Implications for multiple sclerosis therapy
by Mondal, Susanta and Pahan, Kalipada
PLoS ONE, ISSN 1932-6203, 01/2015, Volume 10, Issue 1, pp. e0116566 - e0116566
Upregulation and/or maintenance of regulatory T cells (Tregs) during an autoimmune insult may have therapeutic efficacy in autoimmune diseases. Although... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IL-12P40 HOMODIMER | ACID | METABOLITE SODIUM BENZOATE | MULTIDISCIPLINARY SCIENCES | INHIBITS ADOPTIVE TRANSFER | NITRIC-OXIDE | CENTRAL-NERVOUS-SYSTEM | FOXP3 | CUTTING EDGE | TH17 CELLS | Plant Extracts - chemistry | T-Lymphocytes, Regulatory - metabolism | Spinal Cord - metabolism | Plant Extracts - pharmacology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Incidence | Myelin Sheath - metabolism | T-Lymphocytes, Regulatory - immunology | Th17 Cells - metabolism | Spinal Cord - pathology | T-Lymphocytes, Regulatory - cytology | Female | Th17 Cells - cytology | Demyelinating Diseases - pathology | Disease Models, Animal | Administration, Oral | Cinnamomum zeylanicum - chemistry | Cinnamomum zeylanicum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Mice, Transgenic | Blood-Brain Barrier - metabolism | Animals | Encephalomyelitis, Autoimmune, Experimental - epidemiology | Myelin Proteolipid Protein - genetics | Multiple Sclerosis - immunology | Th17 Cells - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Plant Extracts - therapeutic use | Multiple Sclerosis - drug therapy | Multiple sclerosis | Care and treatment | Research | Encephalomyelitis | Health aspects | Nitric oxide | Drugs | Spinal cord | Central nervous system | Antibodies | Lymphocytes T | Adoptive transfer | Powder | Sclerosis | T-cell receptor | Blood-brain barrier | Myelin proteolipid protein | Demyelination | Lymphocytes | CD25 antigen | Inhibition | Cinnamon | Myelin | Immunoregulation | Immunomodulation | Oral administration | Transgenic mice | Gene expression | Experimental allergic encephalomyelitis | Side effects | Autoimmune diseases | Index Medicus
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7. Full Text Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: Implications for multiple sclerosis therapy
by Navarrete, Carmen and Carrillo-Salinas, Francisco and Palomares, Belén and Mecha, Miriam and Jiménez-Jiménez, Carla and Mestre, Leyre and Feliú, Ana and Bellido, Maria L and Fiebich, Bernd L and Appendino, Giovanni and Calzado, Marco A and Guaza, Carmen and Muñoz, Eduardo
Journal of Neuroinflammation, ISSN 1742-2094, 03/2018, Volume 15, Issue 1, pp. 64 - 64
Background: Multiple sclerosis (MS) is characterized by a combination of inflammatory and neurodegenerative processes variously dominant in different stages of... 
Arginase 1 | Cannabinoids | Multiple sclerosis | PHDs | EPO | VEGF | HIF-1α | NERVOUS-SYSTEM | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | ERYTHROPOIETIN | HIF-1 alpha | CNS REMYELINATION | NITRIC-OXIDE SYNTHASE | MACROPHAGES | OLIGODENDROCYTE PRECURSOR CELLS | IMMUNOLOGY | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | CEREBRAL ENDOTHELIAL-CELLS | GROWTH-FACTOR | Microglia - metabolism | Cell Hypoxia - physiology | Humans | Arginase - metabolism | Neovascularization, Pathologic | Male | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Cell Movement - genetics | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Female | Cell Polarity - drug effects | Disease Models, Animal | Quinones - metabolism | Encephalomyelitis, Autoimmune, Experimental - physiopathology | Cytokines - metabolism | Microglia - drug effects | Endothelial Cells - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Arginase - genetics | Gene Expression Regulation - drug effects | Cell Polarity - genetics | Animals | Macrophages - drug effects | Mice | Cell Line, Transformed | Endothelial Cells - drug effects | Regeneration | Care and treatment | Transcription factors | Immune response | Development and progression | Nervous system | Genetic aspects | Health aspects | Index Medicus
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8. Full Text The future of multiple sclerosis therapy
by Kieseier, Bernd C and Wiendl, Heinz and Hartung, Hans-Peter and Stüve, Olaf
Pharmacological Research, ISSN 1043-6618, 2009, Volume 60, Issue 4, pp. 207 - 211
Multiple sclerosis (MS) represents the prototypic inflammatory autoimmune disorder of the central nervous system and the most common cause of neurological... 
Multiple sclerosis | Immunosuppression | Injectables | Immunomodulation | Oral therapy | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | LAQUINIMOD ABR-215062 | ORAL FINGOLIMOD FTY720 | PROGRESSIVE MS | CONTROLLED PHASE IIB | CLADRIBINE | SPHINGOSINE 1-PHOSPHATE RECEPTORS | IMMUNOMODULATOR | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | DISEASE-MODIFYING THERAPIES | Antibodies, Neoplasm - therapeutic use | Injections, Intravenous | Humans | Antibodies, Monoclonal - therapeutic use | Fumarates - administration & dosage | Toluidines - administration & dosage | Interferon-beta - therapeutic use | Antibodies, Monoclonal, Humanized | Sphingosine - administration & dosage | Injections, Subcutaneous | Propylene Glycols - therapeutic use | Quinolones - therapeutic use | Crotonates - administration & dosage | Interferon-beta - administration & dosage | Toluidines - therapeutic use | Administration, Oral | Fumarates - therapeutic use | Immunologic Factors - administration & dosage | Fingolimod Hydrochloride | Alemtuzumab | Antibodies, Neoplasm - administration & dosage | Cladribine - administration & dosage | Crotonates - therapeutic use | Quinolones - administration & dosage | Sphingosine - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Propylene Glycols - administration & dosage | Cladribine - therapeutic use | Sphingosine - therapeutic use | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy | Monoclonal antibodies | Immunotherapy | Index Medicus
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9. Full Text Natalizumab discontinuation in the increasing complexity of multiple sclerosis therapy
by Sormani, Maria Pia and Stefano, Nicola De
Neurology, ISSN 0028-3878, 04/2014, Volume 82, Issue 17, pp. 1484 - 1485
The infusion of 300 mg of natalizumab every 4 weeks is an effective therapy for reducing disease activity in relapsing-remitting multiple sclerosis (MS).(1,2)... 
TRIAL | RISK STRATIFICATION | CLINICAL NEUROLOGY | Antibodies, Monoclonal, Humanized - therapeutic use | Natalizumab | Humans | Female | Male | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy | Index Medicus | Abridged Index Medicus
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10. Full Text Activation of endogenous neural stem cells for multiple sclerosis therapy
by Michailidou, Iliana and de Vries, Helga E and Hol, Elly M and van Strien, Miriam E
Frontiers in Neuroscience, ISSN 1662-4548, 2015, Volume 8, pp. 454 - 454
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system, leading to severe neurological deficits. Current MS treatment... 
Therapy | Neural stem cells | Multiple sclerosis | Gliogenesis | Neurogenesis | PROGENITOR CELLS | HUMAN BRAIN | CNS REMYELINATION | neural stem cells | multiple sclerosis | therapy | OLIGODENDROCYTE PRECURSOR CELLS | SUBVENTRICULAR ZONE | NEUROSCIENCES | ADULT SVZ | gliogenesis | MYELIN REPAIR | DEMYELINATED AXONS | neurogenesis | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | Multiple Sclerosis | Neural Stem Cells
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11. Induced stem cells as a novel multiple sclerosis therapy
by Xie, Chong and Liu, Yan-Qun and Guan, Yang-Tai and Zhang, Guang-Xian
Current Stem Cell Research and Therapy, ISSN 1574-888X, 05/2016, Volume 11, Issue 4, pp. 313 - 320
Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an... 
Direct transdifferentiation | Multiple sclerosis | Induced pluripotent stem cells | Experimental autoimmune encephalomyelitis | Neural stem cells | Remyelination | Mesenchymal stem cells | MOUSE FIBROBLASTS | PROGENITOR CELLS | neural stem cells | multiple sclerosis | FUNCTIONAL-NEURONS | BONE-MARROW | DIRECT CONVERSION | AUTOIMMUNE ENCEPHALOMYELITIS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | experimental autoimmune encephalomyelitis | mesenchymal stem cells | induced pluripotent stem cells | GENERATION | PLACEBO-CONTROLLED TRIAL | DIAGNOSTIC-CRITERIA | NEURAL PRECURSOR CELLS | remyelination
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12. What nurses know-- multiple sclerosis
by Saunders, Carol
2011, What nurses know, ISBN 9781932603897, xii, 144 p..
"This book discusses what MS is, and what it is not, and how people can live very full and meaningful lives with a diagnosis of MS. MS is a chronic condition,... 
Multiple sclerosis | HEALTH & FITNESS / Diseases / General
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13. Full Text The italian pharmacovigilance program: An observational study of adverse effects of natalizumab in multiple sclerosis therapy
by Giacoppo, Sabrina and Ruscica, Maria and Grimaldi, Luigi Maria and Bramanti, Placido and Mazzon, Emanuela
Medical Science Monitor, ISSN 1234-1010, 09/2017, Volume 23, pp. 4230 - 4240
Background: This study shows the results of a regional pharmacovigilance program on Natalizumab therapy in relapsing-remitting multiple sclerosis (RR-MS)... 
Relapsing-remitting | Multiple sclerosis | Drug-related side effects and adverse reactions | Antibodies | Humanized | Monoclonal | Pharmacovigilance | MEDICINE, RESEARCH & EXPERIMENTAL | Antibodies, Monoclonal, Humanized | CELLS | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | Multiple Sclerosis, Relapsing-Remitting | EFFICACY | Drug-Related Side Effects and Adverse Reactions | 1ST-LINE | FAILURE | Antibodies, Monoclonal, Humanized - therapeutic use | Risk Assessment | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Natalizumab - adverse effects | Male | Adult | Female | Italy | Aged | Cohort Studies | Multiple Sclerosis - drug therapy | Index Medicus
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14. Full Text Patient preferences for disease-modifying drugs in multiple sclerosis therapy: a choice-based conjoint analysis
by Utz, Kathrin S and Hoog, Jana and Wentrup, Andreas and Berg, Sebastian and Lämmer, Alexandra and Jainsch, Britta and Waschbisch, Anne and Lee, De-Hyung and Linker, Ralf A and Schenk, Thomas
Therapeutic Advances in Neurological Disorders, ISSN 1756-2856, 11/2014, Volume 7, Issue 6, pp. 263 - 275
Objectives: With an increasing number of disease-modifying treatments (DMTs) for multiple sclerosis (MS), patient preferences will gain importance in the... 
parenteral | patient preference | choice-based conjoint analysis | oral | treatment frequency | multiple sclerosis | BENEFIT | CLINICAL NEUROLOGY | Original Research
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15. Multiple sclerosis
: diagnosis and therapy
by Weiner, Howard L and Stankiewicz, James M
2012, ISBN 0470654635
Multiple sclerosis | Etiology | therapy
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16. Full Text Defining the clinical course of multiple sclerosis The 2013 revisions
by Lublin, F.D and Reingold, S.C and Cohen, J.A and Cutter, G.R and Sorensen, P.S and Thompson, A.J and Wolinsky, J.S and Balcer, L.J and Banwell, B and Barkhof, F and Bebo, B and Calabresi, P.A and Clanet, M and Comi, G and Fox, R.J and Freedman, M.S and Goodman, A.D and Inglese, M and Kappos, L and Kieseier, B.C and Lincoln, J.A and Lubetzki, C and Miller, A.E and Montalban, X and O'Connor, P.W and Petkau, J and Pozzilli, C and Rudick, R.A and Sormani, M.P and Stuve, O and Waubant, E and Polman, C.H
Neurology, ISSN 0028-3878, 2014, Volume 83, Issue 3, pp. 278 - 286
Accurate clinical course descriptions (phenotypes) of multiple sclerosis (MS) are important for communication, prognostication, design and recruitment of... 
PATHOGENESIS | RADIOLOGICALLY ISOLATED SYNDROME | DIAGNOSIS | CONVERSION | DISEASE | SPINAL-CORD | FOLLOW-UP | NATURAL-HISTORY | BRAIN MRI | CLINICAL NEUROLOGY | Multiple Sclerosis - physiopathology | Humans | Clinical Trials as Topic - standards | Societies, Medical - standards | Multiple Sclerosis - therapy | Consensus | Multiple Sclerosis - classification | Index Medicus | Abridged Index Medicus | Views & Reviews
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