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Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2017, Volume 61, Issue 4
The nucleotide (p) ppGpp is a key regulator of bacterial metabolism, growth, stress tolerance, and virulence. During amino acid starvation, the Escherichia... 
Persistence | Antibiotics | Thiostrepton | Ribosomes | Tolerance | Trimethoprim | ppGpp | Mupirocin | β-lactam | RelA | BACTERIAL PERSISTENCE | AMINOACYL-TRANSFER-RNA | mupirocin | ELONGATION-FACTOR-G | ESCHERICHIA-COLI | thiostrepton | MICROBIOLOGY | beta-lactam | PROTEIN-SYNTHESIS | ribosomes | trimethoprim | BACILLUS-SUBTILIS | STRINGENT RESPONSE | persistence | PHARMACOLOGY & PHARMACY | STAPHYLOCOCCUS-AUREUS | antibiotics | RIBONUCLEIC-ACID SYNTHESIS | tolerance | GUANOSINE TETRAPHOSPHATE | Trimethoprim - pharmacology | Thiostrepton - pharmacology | Ligases - genetics | Ribosomes - metabolism | Guanosine Tetraphosphate - metabolism | Drug Interactions | Isoleucine-tRNA Ligase - genetics | Chloramphenicol - pharmacology | Escherichia coli - metabolism | RNA, Transfer - genetics | Guanosine Tetraphosphate - analogs & derivatives | Subcellular Fractions - drug effects | RNA, Transfer - metabolism | Tetracycline - pharmacology | Drug Tolerance | Ligases - metabolism | Escherichia coli - chemistry | Mupirocin - pharmacology | Subcellular Fractions - metabolism | Tetrahydrofolate Dehydrogenase - metabolism | beta-Lactams - pharmacology | Ligases - antagonists & inhibitors | Escherichia coli - genetics | Ribosomes - drug effects | Protein Biosynthesis - drug effects | Anti-Bacterial Agents - pharmacology | Subcellular Fractions - chemistry | Tetrahydrofolate Dehydrogenase - genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology
Journal Article
Pediatric Pulmonology, ISSN 8755-6863, 03/2014, Volume 49, Issue 3, pp. 230 - 237
ObjectivesThe prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in cystic fibrosis (CF) patients in the United States is approximately 25%.... 
hospital MRSA | spa | staphylococcal cassette chromosome | Panton‐Valentine leukocidin | typing | mec | multi‐center study | community MRSA | Panton-Valentine leukocidin | spa-typing | multi-center study | staphylococcal cassette chromosome mec | STRAINS | PREVALENCE | RESISTANT STAPHYLOCOCCUS-AUREUS | COMMUNITY | ERA | RESPIRATORY SYSTEM | PEDIATRICS | INFECTION | CULTURES | EPIDEMIOLOGY | Linezolid | Sputum - microbiology | Pneumonia, Staphylococcal - complications | Minocycline - pharmacology | United States | Humans | Minocycline - analogs & derivatives | Child, Preschool | Acetamides - pharmacology | Male | Pneumonia, Staphylococcal - microbiology | Staphylococcal Infections - complications | Molecular Typing | Microbial Sensitivity Tests | Penicillin-Binding Proteins | Bacterial Toxins - genetics | Female | Staphylococcal Infections - microbiology | Fusidic Acid - pharmacology | Child | Methicillin-Resistant Staphylococcus aureus - genetics | Pharynx - microbiology | Staphylococcal Protein A - genetics | Bronchoscopy | Leukocidins - genetics | Staphylococcal Infections - drug therapy | Cystic Fibrosis - microbiology | Fosfomycin - pharmacology | Methicillin-Resistant Staphylococcus aureus - drug effects | Tetracycline - pharmacology | Bacterial Proteins - genetics | Cystic Fibrosis - complications | Mupirocin - pharmacology | Sequence Analysis, DNA | DNA, Bacterial - genetics | Trimethoprim, Sulfamethoxazole Drug Combination - pharmacology | Oxazolidinones - pharmacology | Adolescent | Exotoxins - genetics | Anti-Bacterial Agents - pharmacology | Cohort Studies | Analysis | Staphylococcus aureus infections | Cystic fibrosis | Cross infection | Nosocomial infections | Antibacterial agents | Staphylococcus aureus
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2015, Volume 5, Issue 1, pp. 11596 - 11596
Novel antimicrobials and new approaches to developing them are urgently needed. Repurposing already-approved drugs with well-characterized toxicology and... 
SOFT-TISSUE INFECTIONS | IN-VITRO | ANTIBIOTICS | CA-MRSA SKIN | ANTIOXIDANT | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | COMPOUND | DRUGS | AUREUS | EXPRESSION | Methicillin Resistance - drug effects | Skin - microbiology | Skin - metabolism | Humans | Biofilms - growth & development | Host-Pathogen Interactions - drug effects | Organoselenium Compounds - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Microbial Sensitivity Tests | Female | Staphylococcal Infections - microbiology | Biofilms - drug effects | Methicillin-Resistant Staphylococcus aureus - physiology | Cell Survival - drug effects | Staphylococcal Infections - drug therapy | Methicillin-Resistant Staphylococcus aureus - drug effects | Cells, Cultured | Drug Repositioning | Azoles - pharmacology | Mupirocin - pharmacology | Drug Synergism | Daptomycin - pharmacology | Bacterial Toxins - metabolism | Methicillin-Resistant Staphylococcus aureus - metabolism | Animals | Keratinocytes - drug effects | Anti-Bacterial Agents - pharmacology | Mice, Inbred BALB C | Skin - drug effects | Cytokines | Therapeutic applications | Clinical isolates | Staphylococcus infections | Protein biosynthesis | Antimicrobial agents | Inflammation | Vancomycin | Tumor necrosis factor-α | Drug resistance | Bactericidal activity | Methicillin | Interleukin 6 | Biofilms | Interleukin 1 | Tumor necrosis factor-TNF | Skin diseases | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2013, Volume 57, Issue 1, pp. 559 - 568
Journal Article
Journal Article